Global Protein Detection Quantification Market - 2022-2029

Market Overview

Protein detection quantification market size was valued at US$ 2.25 billion in 2021 and is estimated to reach US$ XX million by 2029, growing at a CAGR of 9.60% during the forecast period (2022-2029).

Detection and subsequent quantification of proteins is a vital step in the understanding of post-translational modifications. It assists in understanding the functions of complex networks of peptides for use in medicine and cell biology. Increased demand for quantification of protein in laboratories that are engaged with various activities. These laboratories' activities range from drug dosing and clinical diagnostic testing to protein characterization and are likely to influence industrial growth in the years to come.

Market Dynamics

The global protein detection quantification market growth driven by certain factors such as by rising number of traumatic injuries drives the market. The market growth is also majorly driven by the increasing need to understand chronic diseases at a molecular level and develop therapeutic solutions to encourage these organizations to fund research and development programs are among the key factors driving the market growth.

Increasing need to understand chronic diseases at a molecular level and develop therapeutic solutions to encourage these organizations to fund research and development programs., is expected to drive the market during the forecast period

Public Health Genomics at the National Cancer Institute (NCI) promotes personalized medicine and genomics into public health cancer research to reduce cancer burden across the globe.

Governments are encouraging research activities by raising funds in the proteomics industry. Thus, the protein detection and quantification market are anticipated to grow significantly in the coming years. The presence of organizations such as the Human Proteome Organization, National Cancer Institute (NCI), and Genomic Health Inc. promotes funding to support R&D and product development exercises about the field of proteomics.

Furthermore, proteomic studies carried out for finding the mechanism of physical and chemical degradation pathways of biologics are anticipated to propel progress. In addition to advancements, the development of next-generation protein concentration estimation techniques is expected to drive the market with potential avenues.

Besides, various candidate biomarkers developed through proteomics and genomics research can serve as predictive indexes for producing safer and more effective drugs. In the discovery stage, differential proteomic analysis with the help of mass spectrometry enables the recognition of candidates linked with a specific mechanism relevant to disease progression and affected by drug treatment.

Although technological advancements continue to take place for simplification protein estimation, the high cost of technology and assays are anticipated to restrict the usage of these assays and technologies under certain circumstances. For instance, Mass Spectroscopy (MS), which is often used for functional proteomics, is considered expensive and slow by researchers. In targeted MS, custom antibodies are required for each target to perform immunoaffinity enrichment of peptides. This process is observed to be expensive as well as lengthy.

The increasing need to comprehend various chronic diseases at a molecular level and then develop therapeutic solutions is estimated to support these organizations in investing in research and development programs. Besides, Public Health Genomics at the National Cancer Institute (NCI) boosts the incorporation of genomics and personalized medicine into the research of public health cancer to diminish the burden of cancer all over the world.

COVID-19 Impact Analysis

The COVID-19 outbreak has negatively affected the growth of the market. The centers are closed, and the laboratories are busy with the COVID-19 test, which will hamper the forecast period's market growth.

Industry Analysis

The global protein detection quantification market provides in-depth analysis of the market based on various industry factors such as porter's five force analysis, supply chain analysis, regulatory analysis, pricing analysis etc.

Segment Analysis

The colorimetric assays segment is expected to grow at the fastest CAGR during the forecast period (2022-2029)

The colorimetric assays segment held the largest market share due to its convenience rate and wide availability of the reagents for its implementation. Colorimetric assays are based on the binding of a specific dye to the rhamnolipid.

Colorimetric assays help distinguish a particular enzyme from another, quantitate catalytic activity, and inhibit this activity, generate proliferative and toxicity profiles, and even determine the concentration of proteins in solution. They are a simple and convenient way to visualize biological processes.

In colorimetric assays, the substrate is converted by the enzyme into a soluble, colored reaction product. This allows precise determination of the enzyme activity by optical density, such as peroxidase activity is measured by reducing the substrate in the presence of hydrogen peroxide, producing a soluble chromogen that is measured with a spectrophotometer. These colorimetric assay methods are often used for microtiter plate-based ELISAs in combination with an automated spectrophotometer.

The testing of protein concentration was done using citrate buffer with tetra bromophenol blue, and the change of color observed was from yellow to blue. These are well-known colorimetric assays commonly used in urine analysis. The different chemicals and enzymes were spotted at the last step of the device fabrication and left to dry in the detection zones. Similar glucose and protein tests were tried on devices patterned with different methods.

Kinases and phosphatases mediate various cellular processes like metabolism, gene transcription and translation, protein-protein interactions, and apoptosis through protein phosphorylation and dephosphorylation. For this reason, many different technologies, including various colorimetric assays, exist to detect these enzymes and their activity. This factor will drive the growth of the market in the forecast period.

Geographical Analysis

North America region holds the largest market share of the global protein detection quantification market

North America dominated the global protein detection quantification market and is expected to grow at the highest CAGR during the forecast period. The region is estimated to be driven by the US mainly due to leading market players in the country and a well-established healthcare framework in the US. A combination of factors such as developed infrastructure, an increase in R&D investment, and growing cases of various diseases in the region are the factors attributed to the market growth in the U.S.

Competitive Landscape

The global protein detection quantification market is highly competitive with the presence of several international and local markets. Product diversification, revenue generation, and opportunities intensify Merck & Co., Inc., Danaher, RayBiotech, Inc., Innovate, Shimadzu Corporation, and PerkinElmer Inc, Bio-Rad Laboratories, Inc., Thermo Fisher Scientific, and GE Healthcare are the leading market players with significant market share. The major players are using product development, novel product launches, market expansion, and product diversification strategies for holding their position in the market.

The companies enter into collaborations, mergers, strategic partnerships, and acquisitions to expand their presence and meet the rising demand for protein detection quantification worldwide. For instance, In August 2020, Oil-Dri Corporation of America, the leading manufacturer of sorbent minerals, parent company to Amlan International, announces that the European Patent Office has issued Patent EP 2906238. The patent covers the unique formulation of two existing mineral-based natural feed additives, Varium for poultry and NeoPrime for swine, that help global animal protein producers thrive in an era of antibiotic-free production.

Key Companies to Watch

Bio-Rad Laboratories

Overview: Bio-Rad Laboratories, Inc. is an American company that continued to produce innovative and useful products in the healthcare industry that assist life science researchers in accelerating the discovery process, and medical diagnostic labs obtain faster better results.

Product Portfolio: DC Protein Assay Reagents Package- Reagent pack for colorimetric assays, includes 250 ml alkaline copper tartrate, 2 L dilute Folin reagent, 5 ml surfactant solution; 450 assays.

The global protein detection quantification market report would provide an access to an approx. 40+ market data table, 45+ figures and 180 pages.