PUBLISHER: Fortune Business Insights Pvt. Ltd. | PRODUCT CODE: 1884070
PUBLISHER: Fortune Business Insights Pvt. Ltd. | PRODUCT CODE: 1884070
The global hepatitis A vaccines market is witnessing strong growth due to rising disease prevalence, expanding immunization programs, and increasing government initiatives aimed at preventing hepatitis A infections. According to the report, the market size reached USD 1.24 billion in 2024, is expected to grow to USD 1.26 billion in 2025, and is projected to rise significantly to USD 2.57 billion by 2032, registering a robust CAGR of 10.7% during the forecast period. With a 50% market share in 2024, North America remained the dominant region, reflecting advanced healthcare systems and strong adoption of immunization practices.
Hepatitis A is a viral liver infection transmitted primarily through contaminated food and water or via close personal contact. Symptoms range from fever, nausea, and abdominal discomfort to jaundice and acute liver failure. The infection is particularly prevalent in low- and middle-income regions due to insufficient sanitation, poor hygiene, and restricted access to clean water. As vaccination is the most effective preventive measure, demand for hepatitis A vaccines continues to grow worldwide. Leading companies such as GSK plc, Sanofi, Merck & Co., Inc., and SINOVAC offer globally approved vaccines, contributing to increasing immunization coverage.
Market Drivers
Growing Prevalence of Hepatitis A
Rising hepatitis A cases globally are driving vaccine uptake. Poor sanitation, contaminated water sources, and limited hygiene practices continue to be major risk factors. In Uzbekistan, for example, 9,507 hepatitis A infections among children were reported in the first two months of 2024, highlighting the urgent need for vaccination programs in high-risk regions.
Increased Government Immunization Initiatives
Governments worldwide are expanding national vaccination programs to prevent outbreaks and minimize healthcare expenditures. In the EU/EEA, 4,548 cases were reported in 2022, prompting authorities to reinforce vaccination strategies.
Market Restraints
High Vaccine Costs and Limited Access
Production of hepatitis A vaccines requires cold-chain logistics and stringent regulatory compliance, elevating overall costs. This restricts access in low-income countries. In Mexico, the cost per dose is USD 935.7, and full immunization requires two doses-making the vaccine unaffordable for many. This affordability gap continues to hinder global eradication efforts.
Market Opportunities
Indigenous Vaccine Development in Emerging Markets
Countries such as India and China are investing in domestic vaccine development to reduce reliance on imports. In January 2024, Indian Immunologicals Ltd launched Havisure, India's first indigenously developed hepatitis A vaccine, significantly improving accessibility and affordability. Such regional innovations are expected to create substantial market opportunities through 2032.
Market Challenges
Cold-Chain Inefficiencies
Hepatitis A vaccines must be stored between 2°C and 8°C. Many lower-income regions lack adequate cold-chain infrastructure, resulting in vaccine wastage and reduced immunization coverage. These limitations remain a key barrier to market expansion.
Market Trends
Rising Demand for Traveler Immunization
With global travel increasing, the demand for hepatitis A vaccination among travelers has grown significantly. Travel clinics and pharmacies in high-income countries report strong vaccine uptake as travelers visit hepatitis A-endemic nations. South Korea, for example, strongly recommends at least one dose before travel to at-risk regions.
Segmentation Overview
By Type
The inactivated vaccine segment dominated the market in 2024 due to global approvals and wide availability. In 2023, SINOVAC's inactivated vaccine Healive gained regulatory approval in Kyrgyzstan. Live attenuated vaccines, though effective, remain regionally concentrated in India and China.
By Age Group
The pediatric segment led the market due to established vaccination protocols. The U.S. CDC recommends routine vaccination for all children aged 12-23 months.
By Form
Solution-based vaccines such as Vaqta (Merck) and Havrix (GSK) hold the majority share due to ease of administration. Lyophilized powders remain important for extended shelf life and storage benefits.
By Distribution Channel
Government suppliers dominated in 2024, driven by large-scale procurement programs. In 2025, GAVI allocated USD 250 million to enhance vaccine access in low-income countries.
North America - USD 0.62 Billion in 2024
North America led the global market, supported by high vaccination rates and rising disease incidence. The U.S. alone recorded 44,660 outbreak cases between 2016 and 2020, fueling vaccine demand.
Asia Pacific
Second-largest market with the highest projected CAGR. India, for instance, reported over 6,000 cases in the first half of 2024, prompting rapid vaccine adoption.
Europe
Strong government immunization programs and recent vaccine initiatives contribute to steady growth.
Latin America & Middle East/Africa
Despite lower market shares, rising awareness and targeted health campaigns support gradual adoption.
Conclusion
With the market valued at USD 1.24 billion in 2024, expected to reach USD 1.26 billion in 2025, and projected to attain USD 2.57 billion by 2032, the global hepatitis A vaccines market is positioned for substantial long-term expansion. Increasing disease burden, rising vaccination initiatives, and new indigenous vaccine developments will collectively drive growth throughout the forecast period.
Segmentation By Type
By Age Group
By Form
By Distribution Channel
By Region