PUBLISHER: Fortune Business Insights Pvt. Ltd. | PRODUCT CODE: 2149250
PUBLISHER: Fortune Business Insights Pvt. Ltd. | PRODUCT CODE: 2149250
The global protein assays market size was valued at USD 2.74 billion in 2025 and is projected to grow from USD 2.94 billion in 2026 to USD 5.15 billion by 2034, exhibiting a CAGR of 7.29% during the forecast period. North America dominated the global protein assays market with a 51.82% share in 2025, valued at USD 1.42 billion. Protein assays are essential for measuring protein concentration and supporting drug discovery, proteomics, clinical diagnostics, biomarker analysis, enzyme studies, and biological research.
The market is expanding due to increasing biotechnology research, development of protein therapeutics, growing proteomics activities, and rising investments in pharmaceutical and biotechnology companies. Funding activities are also supporting innovation, including Spear Bio Inc.'s USD 45.0 million Series A funding in July 2024 to accelerate protein research and disease-diagnostic products.
MARKET DRIVERS
Increasing Development of Protein Therapeutics to Propel Market Growth
The growing development of protein-based drugs by pharmaceutical and biotechnology companies is increasing demand for protein assays in research, development, quality control, and therapeutic evaluation. Growing applications in oncology, autoimmune, genetic, and metabolic diseases are further supporting adoption.
MARKET RESTRAINTS
Product Recalls of Protein Assay Instruments to Restrict Market Growth
Recalls involving assay instruments and reagents can reduce customer confidence and negatively affect product adoption. In August 2023, the FDA reported a Class 2 recall involving the Siemens Atellica CH Total Protein II assay because of reagent carryover issues.
MARKET OPPORTUNITIES
Development of MS-Compatible Assays to Create Growth Opportunities
The development of mass-spectrometry-compatible assays is creating opportunities to improve sensitivity, dynamic range, accuracy, and workflow efficiency. In August 2025, Precision Quantomics launched MSQ-DILI, an LC-MS/MS-based assay kit while expanding quantitative proteomics services.
PROTEIN ASSAYS MARKET TRENDS
Integration with Automation and AI-Based Platforms
Automation and AI are increasingly being integrated into laboratory workflows to reduce manual effort, improve consistency, and accelerate protein analysis. In July 2025, Merck KGaA launched the AAW Automated Assay Workstation powered by Opentrons for automated laboratory experiments.
MARKET CHALLENGES
Limited Availability of Skilled Personnel
Protein assay procedures require specialized technical knowledge and trained laboratory personnel. Shortages of skilled professionals may limit implementation and scalability across research institutions and clinical laboratories.
SEGMENTATION ANALYSIS
By Product Type
The market is segmented into kits, reagents & consumables, and instruments. Kits accounted for the dominant share, supported by increasing adoption in protein assays and biomarker testing. Product launches, including Abselion's 2025 expansion of its Amperia assay portfolio, are supporting segment growth.
By Technology
The technology segment includes colorimetric, fluorometric, luminescent, ELISA-based, and other protein quantification methods. Colorimetric protein quantification led with a 35.9% share in 2025, supported by affordability and compatibility with routine laboratory workflows. Fluorometric protein quantification is projected to grow at a 11.30% CAGR, driven by demand for accurate protein analysis.
By Application
Drug discovery & development, proteomics & molecular biology, clinical diagnostics & disease research, and others comprise the application segments. Drug discovery & development held the leading position with a 33.5% share in 2025. Proteomics & molecular biology is expected to expand at a 9.91% CAGR.
By End User
Pharmaceutical & biotechnology companies, academic & research institutes, clinical & diagnostic laboratories, and others form the end-user segments. Pharmaceutical & biotechnology companies accounted for 39.3% in 2025, supported by growing drug discovery activities. Academic & research institutes are projected to grow at a 5.99% CAGR.
PROTEIN ASSAYS MARKET REGIONAL OUTLOOK
North America
North America dominated with 51.82% share in 2025, valued at USD 1.42 billion, and is expected to reach USD 1.63 billion in 2026. The U.S. market was estimated at USD 1.35 billion in 2025, supported by advanced research infrastructure, proteomics activities, and funding.
Europe
Europe represented approximately 25.91%, valued at USD 0.71 billion in 2025, with a projected CAGR of 7.08%. The U.K., Germany, and France were valued at USD 0.16 billion, USD 0.14 billion, and USD 0.11 billion, respectively, in 2025.
Asia Pacific
Asia Pacific accounted for approximately 16.06%, valued at USD 0.44 billion in 2025. China and India were each estimated at approximately USD 0.08 billion. Increasing research activities and biotechnology development are supporting regional expansion.
Latin America and Middle East & Africa
Latin America was valued at approximately USD 0.11 billion in 2025, while the GCC market reached approximately USD 0.03 billion. Both regions are expected to experience moderate growth.
COMPETITIVE LANDSCAPE
The market has a fragmented competitive structure, with companies strengthening their portfolios through research, product launches, and technological development. Key players include Thermo Fisher Scientific Inc., Bio-Rad Laboratories, Abcam Limited, Agilent, Merck KGaA, PerkinElmer, Promega Corporation, and Takara Bio.
KEY INDUSTRY DEVELOPMENTS
In September 2025, Quantum-Si launched its V4 Sequencing Kit for protein sequencing and analysis. Illumina introduced Illumina Protein Prep for large-scale proteomics discovery. In February 2025, Alamar Biosciences launched its NULISAqpcr Custom Assay Development Kit. Syncell raised USD 30 million in December 2024 to commercialize its Microscoop spatial proteomics platform, while Agilent launched an automated parallel capillary electrophoresis system in January 2024.
REPORT COVERAGE
The protein assays market report covers market size and forecast for 2025, 2026, and 2034, market dynamics, drivers, restraints, opportunities, trends, challenges, segmentation by product type, technology, application, and end user, regional analysis, competitive landscape, and key industry developments.
CONCLUSION
The global protein assays market is projected to expand from USD 2.74 billion in 2025 to USD 2.94 billion in 2026 and USD 5.15 billion by 2034, at a 7.29% CAGR. Growth will be supported by expanding protein therapeutics research, proteomics, biotechnology investments, automation, AI-enabled laboratory workflows, and advanced assay technologies. North America remains the leading regional market, while fluorometric technologies, proteomics applications, and innovative MS-compatible assays are expected to create additional opportunities through 2034.
Segmentation By Product Type, Technology, Application, End User, and Region
By Product Type
By Technology
By Application
By End User
By Region