PUBLISHER: Fairfield Market Research | PRODUCT CODE: 1410516
PUBLISHER: Fairfield Market Research | PRODUCT CODE: 1410516
In 2024, the global tumour-induced osteomalacia market recorded impressive revenue of US$ 135 Mn and the market is poised for further advancement, projecting to attain US$ 173 Mn by the year 2031.
The field of medical research continually seeks to address unmet medical needs, and breakthroughs in cellular biology have illuminated pathways towards novel therapeutics. Small molecules like inhibitors are becoming pivotal in comprehending cellular microenvironments and signaling pathways. These molecules offer improved patient tolerability alongside treatment efficacy.
Notably, the tumour-induced osteomalacia treatment landscape boasts a limited clinical pipeline, with only one approved drug, Crystiva, manufactured by Ultragenix Pharmaceuticals and Kyowa Hakko Kirin Co., Ltd., along with its small molecule inhibitor Fibroblast growth factor 23 (FGF-23). This scarcity presents an opportune arena for pharmaceutical companies to invest in pioneering drug discoveries for underserved targets.
The cost of treating tumour-induced osteomalacia can be substantial, hindering market expansion. Surgical procedures for tumour removal can cost between US$ 50,000 to US$ 100,000 in the U.S., with the annual expense for all treatments reaching billions.
Additionally, pricing sensitivity in emerging markets presents barriers to addressing rare diseases. Strict regulations governing cancer and immunological drugs on a global scale, including adherence to FDA and other standards, pose further challenges.
The U.S. accounted for a significant market share in the global tumour-induced osteomalacia market in 2024. Its prominence can be attributed to a highly developed research infrastructure, strong collaborations between research institutes and hospitals, and dedicated programs and funds allocated for orphan drug development and rare disease research.
Japan is poised to exhibit growth in the global tumour-induced osteomalacia market with the emergence of new treatment modalities, post-marketing approvals, and the adoption of drugs approved by the FDA and EU. For instance, in August 2022, the European Commission granted Kyowa Kirin authorization to use CRYSVITA® (burosumab) as a therapy for tumor-induced osteomalacia.
India, with a notable market share in 2024, is projected to expand in the global tumour-induced osteomalacia market. Its burgeoning patient base and growing economy offer substantial opportunities for drug manufacturers, despite pricing competition. India presents lucrative prospects for manufacturing collaborations in the tumour-induced osteomalacia market space.
Leading pharmaceutical companies focus on partnerships to expand product portfolios. Emerging markets see continuous R&D investments, facilitating the development of new pharmaceuticals and drug combinations.
Burosumab -twza
Cinarcalcet
Calcium
Active Vitamin D (Calcitriol/α-calcitriol)
Phosphorus
Elevated Blood Fibroblast Growth Factor 23 (FGF-23)
Serum Calcium, PTH, Vitamin D
Hyperphosphaturia (Secondary Effects of FDF-23)
Hypophosphatemia (Secondary Effects of FDF-23)
Magnetic Resonance Imaging (MRI)
Computed Tomography (CT Scans)
Vitamin D Metabolism and Deficiency
Osteoporosis
Renal Osteodystrophy
Others