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PUBLISHER: GlobalData | PRODUCT CODE: 1780418
PUBLISHER: GlobalData | PRODUCT CODE: 1780418
HER2-Negative Breast Cancer: Epidemiology Forecast to 2034
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PAGES: 85 Pages
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Breast cancer is a malignant tumor originating within the breast tissue. The most common type of breast cancer is invasive breast cancer, which originates from the milk ducts and invades the surrounding breast tissue (Cancer Research UK, 2023a). As it progresses, the cancer can metastasize to other parts of the body via the bloodstream and lymphatic system (American Cancer Society, 2022). According to the World Health Organization (WHO), breast cancer was the most common diagnosed cancer in women in 157 out of 185 countries in 2022 and is the leading cause of cancer death in women globally (IARC, 2020; WHO, 2024). Risk factors include prolonged exposure to endogenous/exogenous sex hormones; gene mutations; a family history of breast cancer; being overweight or obese; physical inactivity; high alcohol consumption; early menarche; late menopause; and clinical factors, such as biopsy-confirmed atypical hyperplasia and having a high breast tissue and bone density (IARC, 2020; American Cancer Society, 2022).
Scope
- HER2-Negative Breast Cancer: Epidemiology Report and Model provide an overview of the risk factors, comorbidities, and the global and historical trends of HER2-negative (HER2-) breast cancer in the eight major markets (8MM: US, France, Germany, Italy, Spain, UK, Japan, and urban China).
- The report includes a 10-year epidemiology forecast for the diagnosed incident cases of all invasive breast cancer, diagnosed incident cases of HER2- breast cancer, and five-year diagnosed prevalent cases of HER2- breast cancer. The diagnosed incident cases of all invasive breast cancer among women are segmented by age (18 years and older), and hormone receptor (HR) status (HER2-/HR+ and HER2-/HR-). The diagnosed incident cases of HER2- breast cancer among women are segmented by stage at diagnosis (stages I, II, I-II, III, and IV). Five-year diagnosed prevalent cases of invasive HER2- breast cancer are segmented by progression to metastatic disease; stage (stages I-II, III, and IV); menopausal status (HER2-/HR+ only); tumor resection; HR positivity (HER2-/HR+ only); mutations and biomarkers; and other HER2 activating mutations.
Reasons to Buy
HER2- breast cancer Epidemiology series will allow you to -
- Develop business strategies by understanding the trends shaping and driving the global HER2- breast cancer markets.
- Quantify patient populations in the global HER2- breast cancer markets to improve product design, pricing, and launch plans.
- Organize sales and marketing efforts by identifying the age groups, HER2- subtypes, breast cancer stages, and genetic groups that present the best opportunities for HER2- breast cancer therapeutics in each of the markets covered.
- Understand magnitude of the HER2- breast cancer population by age, HR status, stage, tumor resection and genetic groups.
Product Code: GDHCER340-25
Table of Contents
Table of Contents
List of Tables
List of Figures
- About GlobalData
1 HER2-Negative (HER2-) Breast Cancer: Executive Summary
- 1.1 Catalyst
- 1.2 Related reports
- 1.3 Upcoming reports
2 Epidemiology
- 2.1 Disease background
- 2.2 Risk factors and comorbidities
- 2.3 Global and historical trends
- 2.4 8MM forecast methodology
- 2.4.1 Sources
- 2.4.2 Forecast assumptions and methods
- 2.4.3 Forecast assumptions and methods: diagnosed incident cases of all invasive breast cancer and HER2- breast cancer
- 2.4.4 Forecast assumptions and methods: diagnosed incident cases of invasive HER2- breast cancer by stage at diagnosis
- 2.4.5 Forecast assumptions and methods: five-year diagnosed prevalent cases of invasive HER2- breast cancer
- 2.4.6 Forecast assumptions and methods: five-year diagnosed prevalent cases of invasive HER2- breast cancer by stage
- 2.4.7 Forecast assumptions and methods: five-year diagnosed prevalent cases of invasive HER2- breast cancer with progression to metastatic disease
- 2.4.8 Forecast assumptions and methods: five-year diagnosed prevalent cases of invasive HER2-/HR+ breast cancer by menopausal status
- 2.4.9 Forecast assumptions and methods: five-year diagnosed prevalent cases of invasive HER2- breast cancer with resectable tumors
- 2.4.10 Forecast assumptions and methods: five-year diagnosed prevalent cases of invasive HER2-/HR+ breast cancer by HR positivity
- 2.4.11 Forecast assumptions and methods: five-year diagnosed prevalent cases of invasive HER2- breast cancer by mutations and biomarkers
- 2.4.12 Forecast assumptions and methods: diagnosed five-year diagnosed prevalent cases of invasive HER2- breast cancer with other HER2 activating mutations
- 2.5 Epidemiological forecast for invasive HER2- breast cancer (2024-34)
- 2.5.1 Diagnosed incident cases of all invasive breast cancer
- 2.5.2 Age-specific diagnosed incident cases of all invasive breast cancer
- 2.5.3 Diagnosed incident cases of invasive HER2-/HR+ breast cancer
- 2.5.4 Diagnosed incident cases of invasive HER2-/HR- breast cancer
- 2.5.5 Diagnosed incident cases of invasive HER2-/HR+ breast cancer and invasive HER2-/HR- breast cancer by stage at diagnosis
- 2.5.6 Five-year diagnosed prevalent cases of invasive HER2-/HR+ breast cancer
- 2.5.7 Five-year diagnosed prevalent cases of invasive HER2-/HR- breast cancer
- 2.5.8 Five-year diagnosed prevalent cases of invasive HER2- breast cancer by stage
- 2.5.9 Five-year diagnosed prevalent cases of invasive HER2- breast cancer with progression to metastatic disease
- 2.5.10 Five-year diagnosed prevalent cases of invasive HER2-/HR+ breast cancer by menopausal status
- 2.5.11 Five-year diagnosed prevalent cases of invasive HER2-/HR+ and HER2-/HR- breast cancer by resectable tumors
- 2.5.12 Five-year diagnosed prevalent cases of invasive HER2-/HR+ breast cancer by HR positivity
- 2.5.13 Five-year diagnosed prevalent cases of invasive HER2- breast cancer by mutations and biomarkers
- 2.5.14 Five-year diagnosed prevalent cases of invasive HER2- breast cancer with other HER2 activating mutations
- 2.6 Discussion
- 2.6.1 Epidemiological forecast insight
- 2.6.2 Limitations of the analysis
- 2.6.3 Strengths of the analysis
3 Appendix
- 3.1 Bibliography
- 3.2 Primary research - prescriber survey
- 3.3 About the authors
- 3.3.1 Epidemiologist
- 3.3.2 Reviewers
- 3.3.3 Vice President of Disease Intelligence and Epidemiology
- 3.3.4 Global Head of Pharma Research, Analysis, and Competitive Intelligence
- Contact Us
Product Code: GDHCER340-25
List of Table
List of Tables
- Table 1: Summary of newly added data types
- Table 2: Summary of updated data types
- Table 3: Risk factors and comorbidities for HER2- breast cancer
- Table 4: 8MM, five-year diagnosed prevalent cases of invasive HER2-/HR+ breast cancer by mutations and biomarkers, N, women, ages >=18 years, 2024
- Table 5: 8MM, five-year diagnosed prevalent cases of invasive HER2-/HR- breast cancer by mutations and biomarkers, N, women, ages >=18 years, 2024
- Table 6: 8MM, five-year diagnosed prevalent cases of invasive HER2-/HR+ breast cancer with other HER2 activating mutations, N, women, ages >=18 years, 2024
- Table 7: 8MM, five-year prevalent cases of invasive HER2-/HR- breast cancer with other HER2 activating mutations, N, women, ages >=18 years, 2024
- Table 8: High-prescribing physicians surveyed, by country
List of Figure
List of Figures
- Figure 1: 8MM, diagnosed incident cases of invasive HER2- breast cancer, women, N, ages >=18 years, 2024 and 2034
- Figure 2: 8MM, five-year diagnosed prevalent cases of invasive HER2- breast cancer, women, N, ages >=18 years, 2024 and 2034
- Figure 3: 8MM, diagnosed incidence of invasive HER2- breast cancer, women, cases per 100,000 population, ages >=18 years, 2014-34
- Figure 4: 8MM, five-year diagnosed prevalence of invasive HER2- breast cancer, women, %, ages >=18 years, 2018-34
- Figure 5: 8MM, sources used to forecast the diagnosed incident cases of all invasive breast cancer
- Figure 6: 8MM, sources used and not used to forecast the diagnosed incident cases of invasive HER2- breast cancer
- Figure 7: 8MM, sources used and not used to forecast the diagnosed incident cases of invasive HER2- breast cancer by stage at diagnosis
- Figure 8: 8MM, sources used to forecast the five-year diagnosed prevalent cases of invasive HER2- breast cancer
- Figure 9: 8MM, sources used to forecast the five-year diagnosed prevalent cases of invasive HER2-/HR+ breast cancer by menopausal status
- Figure 10: 8MM, sources used to forecast the five-year diagnosed prevalent cases of invasive HER2- breast cancer by resectable tumors
- Figure 11: 8MM, sources used to forecast the five-year diagnosed prevalent cases of invasive HER2-/HR+ breast cancer by HR positivity
- Figure 12: 8MM, sources used to forecast the five-year diagnosed prevalent cases of invasive HER2- breast cancer by mutations and biomarkers
- Figure 13: 8MM, sources used to forecast the five-year diagnosed prevalent cases of invasive HER2- breast cancer with other HER2 activating mutations in the 8MM
- Figure 14: 8MM, diagnosed incident cases of all invasive breast cancer, N, women, ages >=18 years, 2024
- Figure 15: 8MM, diagnosed incident cases of all invasive breast cancer by age, N, women, 2024
- Figure 16: 8MM, diagnosed incident cases of invasive HER2-/HR+ breast cancer, N, women, ages >=18 years, 2024
- Figure 17: 8MM, diagnosed incident cases of invasive HER2-/HR- breast cancer, N, women, ages >=18 years, 2024
- Figure 18: 8MM, diagnosed incident cases of invasive HER2-/HR+ breast cancer by stage at diagnosis, N, women, ages >=18 years, 2024
- Figure 19: 8MM, diagnosed incident cases of invasive HER2-/HR- breast cancer by stage at diagnosis, N, women, ages >=18 years, 2024
- Figure 20: 8MM, five-year diagnosed prevalent cases of invasive HER2-/HR+ breast cancer, N, women, ages >=18 years, 2024
- Figure 21: 8MM, five-year diagnosed prevalent cases of invasive HER2-/HR- breast cancer, N, women, ages >=18 years, 2024
- Figure 22: 8MM, five-year diagnosed prevalent cases of invasive HER2-/HR+ breast cancer by stage, N, women, ages >=18 years, 2024
- Figure 23: 8MM, five-year diagnosed prevalent cases of invasive HER2-/HR- breast cancer by stage, N, women, ages >=18 years, 2024
- Figure 24: 8MM, five-year diagnosed prevalent cases of invasive HER2-/HR+ breast cancer with progression to metastatic disease, N, women, ages >=18 years, 2024
- Figure 25: 8MM, five-year diagnosed prevalent cases of invasive HER2-/HR- breast cancer with progression to metastatic disease, N, women, ages >=18 years, 2024
- Figure 26: 8MM, five-year diagnosed prevalent cases of invasive HER2-/HR+ breast cancer by menopausal status, N, women, ages >=18 years, 2024
- Figure 27: 8MM, five-year diagnosed prevalent cases of invasive HER2-/HR+ breast cancer by resectable tumors, N, women, ages >=18 years, 2024
- Figure 28: 8MM, five-year diagnosed prevalent cases of invasive HER2-/HR- breast cancer by resectable tumors, N, women, ages >=18 years, 2024
- Figure 29: 8MM, five-year diagnosed prevalent cases of invasive HER2-/HR+ breast cancer by HR positivity, N, women, ages >=18 years, 2024
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