PUBLISHER: GlobalData | PRODUCT CODE: 2071421
PUBLISHER: GlobalData | PRODUCT CODE: 2071421
Chronic Kidney Disease: Epidemiology Report and Forecast to 2035
Chronic kidney disease (CKD), or chronic renal disease (International Classification of Diseases 10th Revision [ICD-10] code = N18), is a condition characterized by a gradual loss of kidney function over time. This leads to the accumulation of excess fluid and waste in the body. In the early stages, CKD is a largely asymptomatic condition. As the disease progresses, symptoms worsen and eventually lead to kidney failure (Centers for Disease Control and Prevention, 2024). Advanced CKD can lead to dangerous levels of fluid, electrolytes, and waste accumulating in the body (Bentall, 2025). The glomerular filtration rate (GFR), a key measure of kidney function, is determined by the amount of creatinine in the blood. The Kidney Disease Improving Global Outcomes (KDIGO) classification system is considered the standard for GFR measurement and the diagnosis of CKD (Levin et al., 2013).
In the 7MM, the total prevalent cases of CKD are expected to increase from 118,878,006 cases in 2025 to 129,339,791 cases in 2035, at an annual growth rate (AGR) of 0.88%. In 2035, the US will have the highest number of total prevalent cases of CKD in the 7MM, with 44,637,257 cases, and Italy will have the fewest total prevalent cases of CKD with 3,866,846 cases. The diagnosed prevalent cases of CKD are expected to increase from 23,472,472 cases in 2025 to 25,418,095 cases in 2035, at an AGR of 0.83%. In 2035, Japan will have the highest number of diagnosed prevalent cases of CKD in the 7MM, with 5,852,016 cases, and Italy will have the fewest diagnosed prevalent cases of CKD with 957,683 cases. GlobalData epidemiologists attribute the increase in the total and diagnosed prevalent cases of CKD to changes in population dynamics and the diagnosis rate in each market.
Scope
- This report provides an overview of the risk factors, comorbidities, and global and historical trends for CKD in the seven major pharmaceutical markets (7MM: US, France, Germany, Italy, Spain, UK, and Japan).
- It includes a 10-year epidemiological forecast for the total prevalent cases and diagnosed prevalent cases of CKD. The total and diagnosed prevalent cases of CKD are further segmented by age (18-29 years, 30-39 years, and by 10-year age groups up to 80 years and older), sex, and stage (stage I, stage II, stage IIIa, stage IIIb, stage IV, and stage V).
- The diagnosed prevalent cases of CKD are also segmented by dialysis-dependent (including both hemodialysis and peritoneal dialysis) and non-dialysis dependent. The model associated with this report also provides the diagnosed prevalent cases of CKD by comorbidities (hypertension, diabetes, and cardiovascular disease [CVD]).
- This epidemiology forecast for CKD is supported by data obtained from peer-reviewed articles and population-based studies. The forecast methodology was kept consistent across 7MM to allow for a meaningful comparison of the forecasted diagnosed prevalent cases of CKD across these markets.
Table of Contents
Table of Contents
List of Tables
List of Figures
1 Executive Summary
- 1.1 Catalyst
- 1.2 Related reports
- 1.3 Upcoming reports
2 Epidemiology
- 2.1 Disease background
- 2.2 Risk factors and comorbidities
- 2.3 Global and historical trends
- 2.4 7MM forecast methodology
- 2.4.1 Sources
- 2.4.2 Forecast assumptions and methods
- 2.4.3 Forecast assumptions and methods: total prevalent cases of CKD
- 2.4.4 Forecast assumptions and methods: total prevalent cases of CKD by stage
- 2.4.5 Diagnosed prevalent cases of CKD
- 2.4.6 Diagnosed prevalent cases of CKD by stage
- 2.4.7 Diagnosed prevalent cases of CKD based on dialysis dependence
- 2.5 Epidemiological forecast for CKD (2025-35)
- 2.5.1 Total prevalent cases of CKD
- 2.5.2 Total prevalent cases of CKD by stage
- 2.5.3 Diagnosed prevalent cases of CKD
- 2.5.4 Age-specific diagnosed prevalent cases of CKD
- 2.5.5 Sex-specific diagnosed prevalent cases of CKD
- 2.5.6 Diagnosed prevalent cases of CKD by stage
- 2.5.7 Diagnosed prevalent cases of CKD by dialysis dependence
- 2.6 Discussion
- 2.6.1 Epidemiological forecast insight
- 2.6.2 Limitations of the analysis
- 2.6.3 Strengths of the analysis
3 Appendix
- 3.1 Bibliography
- 3.2 About the Authors
- 3.2.1 Epidemiologist
- 3.2.2 Reviewers
- 3.2.3 Vice President of Disease Intelligence and Epidemiology
- 3.2.4 Global Head of Pharma Research, Analysis, and Competitive Intelligence
- About GlobalData
- Contact Us
List of Table
List of Tables
- Table 1: Summary of updated data types
- Table 2: KDIGO classification of CKD
- Table 3: Risk factors and comorbidities for CKD
List of Figure
List of Figures
- Figure 1: 7MM, total prevalent cases of CKD, both sexes, N, age >=18 years, 2025 and 2035
- Figure 2: 7MM, diagnosed prevalent cases of CKD, both sexes, N, >=18 years, 2025 and 2035
- Figure 3: 7MM, total prevalence of CKD, men and women, %, >=18 years, 2015-35
- Figure 4: 7MM, diagnosed prevalence of CKD, men and women, %, >=18 years, 2015-35
- Figure 5: 7MM, sources used to forecast the total prevalent cases of CKD
- Figure 6: 7MM, sources used to forecast the total prevalent cases of CKD by stage
- Figure 7: 7MM, sources used to forecast the diagnosed prevalent cases of CKD
- Figure 8: 7MM, sources used to forecast the diagnosed prevalent cases of CKD by stage
- Figure 9: 7MM, sources used to forecast the diagnosed prevalent cases of CKD by dialysis dependence
- Figure 10: 7MM, total prevalent cases of CKD, N, both sexes, ages >=18 years, 2025
- Figure 11: 7MM, total prevalent cases of CKD by stage, N, both sexes, ages >=18 years, 2025
- Figure 12: 7MM, diagnosed prevalent cases of CKD, N, both sexes, ages >=18 years, 2025
- Figure 13: 7MM, diagnosed prevalent cases of CKD by age, N, both sexes, 2025
- Figure 14: 7MM, diagnosed prevalent cases of CKD by sex, N, ages >=18 years, 2025
- Figure 15: 7MM, diagnosed prevalent cases of CKD by stage, N, ages >=18 years, 2025
- Figure 16: 7MM, diagnosed prevalent cases of CKD by dialysis dependence, N, both sexes, ages >=18 years, 2025
- Figure 17: 7MM, diagnosed prevalent cases of CKD based on dialysis-dependence subtype, N, both sexes, ages >=18 years, 2025
