PUBLISHER: Global Industry Analysts, Inc. | PRODUCT CODE: 1733958
PUBLISHER: Global Industry Analysts, Inc. | PRODUCT CODE: 1733958
Global In-Vivo CRO Market to Reach US$7.2 Billion by 2030
The global market for In-Vivo CRO estimated at US$4.6 Billion in the year 2024, is expected to reach US$7.2 Billion by 2030, growing at a CAGR of 7.8% over the analysis period 2024-2030. Small Molecules, one of the segments analyzed in the report, is expected to record a 9.0% CAGR and reach US$5.1 Billion by the end of the analysis period. Growth in the Large Molecules segment is estimated at 5.3% CAGR over the analysis period.
The U.S. Market is Estimated at US$1.2 Billion While China is Forecast to Grow at 12.4% CAGR
The In-Vivo CRO market in the U.S. is estimated at US$1.2 Billion in the year 2024. China, the world's second largest economy, is forecast to reach a projected market size of US$1.5 Billion by the year 2030 trailing a CAGR of 12.4% over the analysis period 2024-2030. Among the other noteworthy geographic markets are Japan and Canada, each forecast to grow at a CAGR of 3.8% and 7.6% respectively over the analysis period. Within Europe, Germany is forecast to grow at approximately 5.2% CAGR.
Global In-Vivo CRO Market - Key Trends & Drivers Summarized
Why Are In-Vivo CRO Services Gaining Strategic Importance in Drug Development?
In-vivo contract research organizations (CROs) play a critical role in the pharmaceutical and biotechnology industries by providing outsourced preclinical and early-stage research services involving live animal models. These studies are essential to evaluate the pharmacokinetics, pharmacodynamics, efficacy, and safety of drug candidates before progressing to human trials. As regulatory scrutiny and drug development costs rise, sponsors are increasingly turning to specialized in-vivo CROs for their technical expertise, regulatory knowledge, and capacity to accelerate timelines while ensuring scientific rigor.
The rising complexity of therapeutics-including biologics, gene therapies, and personalized medicines-requires more sophisticated animal testing protocols that many in-house facilities cannot adequately support. In-vivo CROs offer customized study designs, validated models for specific disease indications, and advanced imaging and telemetry capabilities. Their ability to manage genetically engineered animal models, conduct toxicology studies, and support investigational new drug (IND) submissions makes them indispensable partners in preclinical research pipelines.
How Are Technology and Specialization Advancing the Capabilities of In-Vivo CROs?
Technological innovation is reshaping the landscape of in-vivo research services, enabling CROs to deliver higher accuracy, reproducibility, and insight into complex biological responses. Real-time imaging technologies such as MRI, PET, and optical imaging allow for non-invasive monitoring of disease progression and therapeutic impact. Advanced telemetry systems enable continuous measurement of vital signs, behavioral changes, and physiological parameters, reducing the number of animals required while improving data quality.
CROs are also expanding their portfolios to include specialized disease models-such as oncology, autoimmune disorders, rare diseases, and CNS pathologies-tailored to meet the evolving needs of biopharma companies. The development of humanized mouse models and transgenic strains has made it possible to conduct more translational research, bridging the gap between animal and human responses. Integration of digital lab notebooks, automated data capture systems, and AI-based data analysis tools is further increasing operational efficiency and scientific accuracy across in-vivo studies.
Which Segments and Regions Are Driving the Expansion of the In-Vivo CRO Market?
Pharmaceutical and biotechnology companies are the primary clients fueling demand for in-vivo CRO services, especially mid-size and emerging biotech firms that rely heavily on external partners due to limited internal R&D infrastructure. Increasing demand is also seen from academic research institutions and government-sponsored initiatives focused on translational medicine, vaccine development, and rare disease research. The oncology and CNS therapeutic areas represent the largest application segments, owing to the extensive animal modeling required to study tumor behavior and neurological functions.
North America dominates the global in-vivo CRO market, supported by a robust biopharmaceutical R&D ecosystem, established regulatory frameworks, and a high concentration of contract research infrastructure. Europe follows closely, with strong demand across Germany, the UK, and France. Asia-Pacific is emerging as a high-growth region, led by China and India, where cost advantages, regulatory reforms, and expanding local biopharma sectors are attracting outsourcing activity. Additionally, growing interest in ethical animal research and adherence to Good Laboratory Practice (GLP) standards in these regions is helping align local CROs with global clients’ expectations.
The Growth in the In-Vivo CRO Market Is Driven by Several Factors…
It is driven by the increasing complexity of drug candidates, which necessitates advanced animal modeling to evaluate safety and efficacy prior to clinical trials. Biopharmaceutical companies are increasingly outsourcing in-vivo studies to reduce fixed R&D costs, access specialized expertise, and accelerate timelines in competitive therapeutic areas. The expanding pipeline of biologics, cell and gene therapies, and novel delivery systems further amplifies the need for sophisticated in-vivo capabilities that can simulate human-like responses.
In parallel, advances in non-invasive imaging, telemetry, and disease model customization are enhancing the value proposition of in-vivo CROs, making them strategic partners in early-stage decision-making. Regulatory emphasis on well-documented, ethically conducted animal studies-especially for IND filings-continues to reinforce the importance of standardized, GLP-compliant service providers. Furthermore, the increasing demand for personalized and orphan drugs is creating a need for more targeted and adaptable in-vivo studies. These combined factors are ensuring steady and sustained growth of the in-vivo CRO market as a critical enabler of modern drug discovery and development.
SCOPE OF STUDY:
The report analyzes the In-Vivo CRO market in terms of units by the following Segments, and Geographic Regions/Countries:
Segments:
Type of Molecule (Small Molecules, Large Molecules); Therapeutic Area (Oncology, Cardiology, Diabetes, Autoimmune / Inflammation Conditions, Infectious Diseases, CNS Conditions, Other Therapeutic Areas); Service Type (Preclinical Testing, Clinical Research Services, Laboratory Services, Consulting Services, Other Service Types)
Geographic Regions/Countries:
World; United States; Canada; Japan; China; Europe (France; Germany; Italy; United Kingdom; Spain; Russia; and Rest of Europe); Asia-Pacific (Australia; India; South Korea; and Rest of Asia-Pacific); Latin America (Argentina; Brazil; Mexico; and Rest of Latin America); Middle East (Iran; Israel; Saudi Arabia; United Arab Emirates; and Rest of Middle East); and Africa.
Select Competitors (Total 39 Featured) -
TARIFF IMPACT FACTOR
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APRIL 2025: NEGOTIATION PHASE
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JULY 2025 FINAL TARIFF RESET
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Reciprocal and Bilateral Trade & Tariff Impact Analyses:
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