PUBLISHER: Global Industry Analysts, Inc. | PRODUCT CODE: 1794671
PUBLISHER: Global Industry Analysts, Inc. | PRODUCT CODE: 1794671
Global Pulmonary Embolism Therapeutics Market to Reach US$40.6 Billion by 2030
The global market for Pulmonary Embolism Therapeutics estimated at US$22.1 Billion in the year 2024, is expected to reach US$40.6 Billion by 2030, growing at a CAGR of 10.7% over the analysis period 2024-2030. Oral Administration, one of the segments analyzed in the report, is expected to record a 12.0% CAGR and reach US$27.2 Billion by the end of the analysis period. Growth in the Parenteral Administration segment is estimated at 8.2% CAGR over the analysis period.
The U.S. Market is Estimated at US$6.0 Billion While China is Forecast to Grow at 14.7% CAGR
The Pulmonary Embolism Therapeutics market in the U.S. is estimated at US$6.0 Billion in the year 2024. China, the world's second largest economy, is forecast to reach a projected market size of US$8.5 Billion by the year 2030 trailing a CAGR of 14.7% over the analysis period 2024-2030. Among the other noteworthy geographic markets are Japan and Canada, each forecast to grow at a CAGR of 7.5% and 9.5% respectively over the analysis period. Within Europe, Germany is forecast to grow at approximately 8.4% CAGR.
Global Pulmonary Embolism Therapeutics Market - Key Trends & Drivers Summarized
Why Is Pulmonary Embolism Therapy Becoming a Priority in Acute and Preventive Care Frameworks?
Pulmonary embolism (PE), characterized by a blockage in the pulmonary arteries due to a blood clot, represents one of the most life-threatening cardiovascular emergencies globally. Despite its high morbidity and mortality rates, PE is frequently underdiagnosed due to its varied clinical presentation, ranging from asymptomatic episodes to sudden death. Advances in imaging techniques, improved diagnostic algorithms, and increased clinical awareness have led to rising incidence rates-necessitating scalable and stage-specific therapeutic options.
The management of PE spans acute intervention, stabilization, and long-term recurrence prevention. Treatment regimens are driven by risk stratification models such as the Pulmonary Embolism Severity Index (PESI), determining whether patients require hospitalization or outpatient care. High-risk PE patients, particularly those with hemodynamic instability, are often managed with systemic thrombolysis or catheter-directed thrombolysis. The standard of care for most low to intermediate-risk cases includes anticoagulant therapy with agents such as low-molecular-weight heparin (LMWH), direct oral anticoagulants (DOACs), or unfractionated heparin (UFH).
Which Drug Classes and Intervention Technologies Are Shaping the Current Treatment Landscape?
Anticoagulants remain the cornerstone of pulmonary embolism therapy. The transition from traditional Vitamin K antagonists like warfarin to DOACs such as rivaroxaban, apixaban, and edoxaban has transformed outpatient management by offering fixed dosing, reduced monitoring, and fewer dietary interactions. These agents are now preferred for the majority of non-massive PE cases and have demonstrated comparable efficacy with better safety profiles. LMWH is still widely used in initial hospital-based care and in special populations such as cancer patients and pregnant women.
Thrombolytic therapy, while effective in dissolving clots, carries a significant risk of bleeding and is generally reserved for high-risk PE with right ventricular dysfunction. Newer catheter-directed thrombolysis systems, such as the EKOS endovascular system, deliver targeted thrombolytics directly to the clot, minimizing systemic exposure. Mechanical thrombectomy devices are being deployed in select cases to remove large clots with reduced hemorrhagic risk. Inferior vena cava (IVC) filters, although controversial due to complications, are occasionally used in patients with contraindications to anticoagulation. The development of hybrid protocols combining pharmacological and interventional therapies is becoming increasingly common.
How Are Clinical Guidelines, Patient Stratification, and Health System Protocols Influencing Market Trends?
Updated clinical guidelines from bodies such as the American College of Chest Physicians (ACCP), European Society of Cardiology (ESC), and National Institute for Health and Care Excellence (NICE) emphasize early discharge, outpatient management, and personalized treatment planning. These protocols reflect advances in diagnostic tools, including D-dimer assays, CT pulmonary angiography, and point-of-care ultrasound, which facilitate rapid risk assessment and triaging. The emergence of PE response teams (PERTs) in hospitals is also transforming decision-making by bringing together multidisciplinary teams to optimize individualized care.
Further, health systems are adopting digital tools for anticoagulant dose tracking, adherence monitoring, and telehealth consultations-especially important in chronic PE or post-discharge settings. Registries such as the International Cooperative Pulmonary Embolism Registry (ICOPER) and RIETE provide valuable real-world data on treatment outcomes and guide evidence-based refinements in care standards. Special attention is being directed toward long-term complications such as chronic thromboembolic pulmonary hypertension (CTEPH), which necessitates surgical or balloon pulmonary angioplasty interventions.
What Factors Are Driving the Growth of the Global Pulmonary Embolism Therapeutics Market?
The growth in the global pulmonary embolism therapeutics market is driven by increasing incidence of thromboembolic events, rising adoption of DOACs, and expansion of interventional technologies. Sedentary lifestyles, obesity, malignancies, and post-operative complications are contributing to the growing burden of venous thromboembolism (VTE), with PE accounting for a significant share of emergency admissions worldwide. Improved awareness among healthcare professionals and patients has led to earlier detection and broader treatment coverage.
Pharmaceutical innovation continues to shape market expansion. Pipeline candidates targeting Factor XI and Factor XII pathways aim to reduce thrombotic risk with minimal bleeding complications, which could further improve treatment options for vulnerable populations. Additionally, AI-powered diagnostic tools and predictive analytics platforms are being tested to identify high-risk individuals proactively. Healthcare infrastructure development in emerging economies is expanding access to timely PE diagnosis and management.
Key industry participants include Bayer AG, Bristol-Myers Squibb, Pfizer, Boehringer Ingelheim, Johnson & Johnson (Janssen), Inari Medical, and Penumbra Inc. Strategic partnerships between pharma and device companies are accelerating the integration of therapeutic and interventional care models. As risk stratification protocols, outpatient management, and precision medicine approaches mature, the pulmonary embolism therapeutics market is poised for robust growth across both pharmacological and procedural domains.
SCOPE OF STUDY:
The report analyzes the Pulmonary Embolism Therapeutics market in terms of units by the following Segments, and Geographic Regions/Countries:
Segments:
Administration Route (Oral Administration, Parenteral Administration); Application (Hospitals Application, Ambulatory Surgery Centers Application, Research Institutes Application)
Geographic Regions/Countries:
World; United States; Canada; Japan; China; Europe (France; Germany; Italy; United Kingdom; Spain; Russia; and Rest of Europe); Asia-Pacific (Australia; India; South Korea; and Rest of Asia-Pacific); Latin America (Argentina; Brazil; Mexico; and Rest of Latin America); Middle East (Iran; Israel; Saudi Arabia; United Arab Emirates; and Rest of Middle East); and Africa.
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