PUBLISHER: Grand View Research | PRODUCT CODE: 1790427
PUBLISHER: Grand View Research | PRODUCT CODE: 1790427
Antibiotics Market Summary
The global antibiotics market size was estimated at USD 53.07 billion in 2024 and is projected to reach USD 74.07 billion by 2033, growing at a CAGR of 3.71% from 2025 to 2033, major factor contributing to market growth. The antibiotics market is driven by the prevalence of bacterial infections.
Respiratory tract infections (RTIs), such as pneumonia and bronchitis, are among the most widespread, for instance, in May 2025, the CDC estimated that the U.S. experienced between 47-82 million flu illnesses, 21 million medical visits, and 640,000 hospitalizations, based on data from 2024 - 2025. These preliminary figures, derived from weekly influenza surveillance and mathematical modeling, reflect the season's disease burden, often leading to secondary bacterial infections requiring antibiotics. Urinary tract infections (UTIs) follow closely, with over 150 million cases annually worldwide, according to BMC Infectious Diseases, making them a leading cause of antibiotic use. Skin and soft tissue infections (SSTIs), such as cellulitis, are also significant, especially in outpatient care. Hospital-acquired infections (HAIs), including Clostridium difficile and methicillin-resistant Staphylococcus aureus (MRSA), further increase demand. These infections are fueled by urbanization, aging populations, and rising antimicrobial resistance (AMR), which reduces the efficacy of existing treatments. High infection rates in developing regions with limited healthcare access further amplify the need for antibiotics, sustaining market growth despite resistance challenges.
Research and development (R&D) in antibiotics face hurdles due to high costs and low profitability. Developing new antibiotics is expensive, with clinical trials and regulatory demands adding to the burden, while short treatment durations limit returns. However, initiatives such as in April 2025, CARB-X awarded ArrePath USD 3.7 million to develop a novel antibiotic targeting multidrug-resistant Enterobacterales, focusing on complicated urinary tract infections. Using an AI-driven platform, ArrePath identified inhibitors with a unique mechanism, potentially offering oral and IV treatment options to combat antimicrobial resistance effectively. For example, Pfizer partnered with AbbVie in 2023 to develop novel antibiotic combinations, sharing costs and risks. The Global AMR R&D Hub also coordinates international efforts to bolster the antibiotic pipeline. Despite these measures, challenges persist, as resistance develops quickly, reducing the lifespan of new drugs. Sustained public-private collaboration is critical to overcoming these barriers and ensuring the development of effective antibiotics to combat rising resistance.
Key players in the antibiotics market employ strategies such as mergers, partnerships, and innovation to stay competitive. In February 2025, key biotech deals included Novartis acquiring Anthos Therapeutics for up to $2.15 billion ($925 million upfront) for its stroke prevention program, Eli Lilly buying Organovo's FXR program for inflammatory bowel disease (terms undisclosed), and the merger of Alumis and Acelyrin, focusing on immune-mediated diseases with a $737 million cash runway. In 2023, Merck invested over USD 674 million partnering with Exscientia to apply AI in drug development, manufacturing, and regulatory processes. Additionally, Merck joined forces with BenevolentAI, investing hundreds of millions more in AI drug discovery platforms. Smaller firms like Entasis Therapeutics, which gained FDA approval for Xacduro in 2023 for pneumonia, target niche markets. Companies such as GSK also promote antibiotic stewardship to encourage responsible use. However, generic competition and the need for constant innovation amid resistance pressures challenge profitability. These developments reflect a dynamic market where firms balance cost management with the pursuit of novel antibiotics to maintain their edge.
Global Antibiotics Market Report Segmentation
This report forecasts revenue growth at global, regional & country levels and provides an analysis on the industry trends in each of the sub-segments from 2021 to 2033. For the purpose of this study, Grand View Research has segmented the global antibiotics market report on the basis of drug class, type, action mechanism, and region: