PUBLISHER: Grand View Research | PRODUCT CODE: 1842007
PUBLISHER: Grand View Research | PRODUCT CODE: 1842007
The global intraoperative radiation therapy market size was estimated at USD 121.74 million in 2024 and is projected to reach USD 247.14 million by 2033, growing at a CAGR of 8.2% from 2025 to 2033. The intraoperative radiation therapy (IORT) market is expanding in response to the rising cancer burden.
According to the World Health Organization's report published in February 2024, there were 20 million new cases and 9.7 million deaths reported in 2022. IORT devices, including mobile linear accelerators, compact X-ray platforms, and brachytherapy systems, enable precise delivery of radiation directly to the tumor bed during surgery. This targeted approach reduces exposure to surrounding healthy tissues and minimizes local recurrence risks. With 53.5 million patients living within five years of a cancer diagnosis, hospitals, and specialty centers are increasingly adopting these devices to improve long-term outcomes. The lifetime cancer risk of 1 in 5 people further highlights the need for patient-centric devices that streamline treatment and improve adherence.
Breast and colorectal cancers are key drivers for IORT device adoption due to their high incidence rates. In 2022, breast cancer accounted for 2.3 million new cases (11.6%), while colorectal cancer contributed 1.9 million new cases (9.6%). Hospitals are deploying electron-based IORT systems, low-energy X-ray devices, and applicator-guided brachytherapy tools to deliver high-dose intraoperative radiation in a single session. This reduces the need for extended postoperative radiotherapy. These devices improve local tumor control, shorten treatment timelines, and reduce hospitalization costs. Patient convenience and workflow efficiency are critical advantages, encouraging wider integration of IORT systems in surgical oncology suites globally across hospitals and specialty centers.
The IORT device market is expected to grow as the global cancer burden rises, with over 35 million new cases predicted by 2050, representing a 77% increase from 2022. Population growth, aging, and lifestyle risk factors such as tobacco, alcohol, obesity, and environmental exposures drive this surge. High HDI countries are projected to see the most significant absolute increase, with 4.8 million additional cases, while low HDI countries could experience a 142% proportional increase and medium HDI countries 99%. The projected doubling of cancer mortality in these regions underscores the need for advanced devices capable of delivering precise, efficient treatment. The growing adoption of electron accelerators, X-ray IORT systems, and brachytherapy devices will be central to addressing rising clinical demand worldwide.
The 2022 global cancer incidence data reveals significant regional disparities, with Asia reporting the highest cases (≈9.8 million), followed by Europe (4.47M), North America (2.67M), Africa (1.55M), and Latin America/Caribbean (1.18M). This highlights the urgent need for region-specific cancer management and advanced therapies. Intraoperative Radiation Therapy (IORT), delivering targeted radiation during surgery, offers precise treatment while minimizing healthy tissue exposure, particularly valuable in high-incidence regions such as Asia and Europe. Rising cancer rates in North America and Africa also boost demand for advanced modalities. Adoption of IORT can shorten treatment duration, reduce hospitalization costs, and enhance patient outcomes. Expanding healthcare infrastructure, favorable reimbursement policies, and innovations in compact IORT systems are expected to drive global market growth.
Global Intraoperative Radiation Therapy Market Report Segmentation
This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, Grand View Research has segmented the global intraoperative radiation therapy market report based on technology, application, end-use, and region: