PUBLISHER: Grand View Research | PRODUCT CODE: 1888591
PUBLISHER: Grand View Research | PRODUCT CODE: 1888591
The global pulmonary arterial hypertension market size was estimated at USD 8.02 billion in 2024 and is projected to reach USD 13.34 billion by 2033, growing at a CAGR of 5.9% from 2025 to 2033. The market growth is majorly attributed to increasing support from government & healthcare authorities for new drug development, rising prevalence of pulmonary arterial hypertension, and favorable reimbursement policies.
In addition, substantial research and development activities in the field of pulmonary arterial hypertension are also projected to have a positive impact on the market's growth. For instance, in December 2023, a group of researchers form Cedars-Sinai revealed that unique-cell based approach is well suited for treatment of pulmonary arterial hypertension. Currently, the study in phase I of clinical trials.
The PAH market thrives on significant investments from industry leaders and governments, targeting the unmet needs of this rare condition. Growth is driven by increasing PAH incidence linked to lifestyle factors such as smoking and HIV, alongside aging populations. Government policies, such as the U.S. Orphan Drug Act, incentivize drug development, boosting market expansion. Enhanced diagnostic capabilities and awareness further accelerate demand for effective therapies.
Prostacyclin and analogs, holding 47.11% of 2024 revenue, remain pivotal, with drugs such as epoprostenol and selexipag offers vasodilation benefits. Their ability to improve pulmonary blood flow and patient quality of life underpins their market leadership. Innovations like oral formulations enhance accessibility, and drive segment growth through improved patient adherence.
Sotatercept (Winrevair) has been FDA approved in March 2024 for the treatment of adults with pulmonary arterial hypertension (PAH). It is the first activin signaling inhibitor approved for PAH, shown to increase exercise capacity, improve WHO functional class, and reduce the risk of clinical worsening events.
Emerging technologies, such as the Remunity Pump launched in 2021, revolutionize drug delivery, offering subcutaneous treprostinil administration. Digital health tools, including wearables, enable real-time monitoring, personalizing PAH management. These advancements, paired with a strong R&D pipeline, promise to reshape treatment paradigms and sustain market momentum through 2033.
Global Pulmonary Arterial Hypertension Market Report Segmentation
This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, Grand View Research has segmented the global pulmonary arterial hypertension market report based on drug class, type, route of administration, and region: