PUBLISHER: Grand View Research | PRODUCT CODE: 1908669
PUBLISHER: Grand View Research | PRODUCT CODE: 1908669
The global plant-based API market size was estimated at USD 31.78 billion in 2024 and is projected to reach USD 53.21 billion by 2033, growing at a CAGR of 5.9% from 2025 to 2033. The market is progressing steadily as pharmaceutical companies shift toward natural-origin ingredients supported by strong therapeutic relevance.
Demand is increasing as patients and clinicians show greater confidence in botanical actives that deliver cleaner impurity profiles and favorable safety outcomes. For instance, in September 2025, Current Issues in Molecular Biology published a review describing how metabolic engineering raised terpenoid production, including paclitaxel, by 25-fold and enhanced artemisinin yield by 38% in engineered systems. Multi-omics approaches, including genomics, transcriptomics, and metabolomics, revealed key biosynthetic genes and regulatory networks. Meanwhile, CRISPR tools, enzyme engineering, and subcellular targeting addressed the low natural yields, which often fall below 0.05% dry weight.
The review highlighted challenges such as metabolic flux balancing, cytotoxicity, and scale-up costs, proposing a roadmap to translate lab-scale terpenoid production into industrial manufacturing. This growing interest is encouraging manufacturers to upgrade extraction and purification systems that ensure uniform potency and regulatory compliance across production batches. Drug developers are strengthening pipelines that feature phyto-derived compounds for chronic and lifestyle-driven conditions, which helps establish consistent market momentum. The industry is further supported by scalable cultivation networks that secure dependable raw material availability, allowing producers to maintain continuous output and deliver a stable supply across global markets.
Global Plant-based API Market Report Segmentation
This report forecasts revenue growth at the global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, Grand View Research has segmented the global plant-based API market report based on molecule type, end use, and region: