PUBLISHER: IMARC | PRODUCT CODE: 1820076
PUBLISHER: IMARC | PRODUCT CODE: 1820076
Natural Killer Cells Therapeutics Market Report by Therapeutics, Application, End User, and Region 2025-2033
The global natural killer cells therapeutics market size reached USD 3.2 Billion in 2024. Looking forward, IMARC Group expects the market to reach USD 8.6 Billion by 2033, exhibiting a growth rate (CAGR) of 11.8% during 2025-2033. The rising risks of developing cancer, along with the expanding geriatric population, are propelling the market.
Natural Killer Cells Therapeutics Market Trends:
Increasing Popularity of Combination Therapies
Combining NK cell therapies with other treatment modalities to enhance therapeutic efficacy is gaining extensive traction. For example, Innate Pharma's Lumoxiti, an anti-CD22 immunotoxin, is adopted in conjunction with NK cells to destroy and target CD22-expressing cancer cells in hairy cell leukemia. Moreover, this approach leverages the strengths of both therapies. Besides this, in May 2024, Coeptis Therapeutics Holdings, Inc., a biopharmaceutical company developing innovative cell therapy platforms for autoimmune, cancer, and infectious diseases, introduced SNAP-CAR NK cells to target multiple antigens.
Growing Regulatory Approval
The rising focus among government agencies on enhancing the reliability and efficiency of NK cell production is acting as a significant growth-inducing factor. Furthermore, they are encouraging the translation of laboratory research into viable clinical therapies, which will continue to fuel the market over the foreseeable future. For example, in April 2024, Ingenium Therapeutics, a leading innovator in next-generation NK cell therapies, received an Orphan Drug Designation from the U.S. Food and Drug Administration (FDA) for the treatment of acute myeloid leukemia (AML).
Rising Demand for Real-Time Monitoring
The widespread integration of real-time monitoring and data analytics into NK cell therapy development is enhancing treatment precision and patient outcomes. Moreover, platforms like Bio-Techne's Ella system enable precise monitoring of cytokine production during NK cell expansion, thereby ensuring optimal cell functionality. Real-time analytics also allow researchers to adjust culture conditions dynamically, which aids in improving the quality and effectiveness of the NK cells produced. This is positively influencing the market.
Global Natural Killer Cells Therapeutics Industry Segmentation:
Breakup by Therapeutics:
- NK Cell Therapies
- NK Cell Directed Antibodies
Currently, NK cell directed antibodies hold the majority of the total market share
NK cell directed antibodies target natural killer cells to enhance their ability to recognize and destroy cancer cells. For example, Affimed's AFM13, a bispecific NK cell engager, targets CD30 on cancer cells and CD16A on NK cells.
Breakup by Application:
- Cancer
- Gastrointestinal Diseases
- Immunoproliferative Disorders
- Others
Cancer currently exhibits a clear dominance in the market
The inflating need for effective cancer treatments drives the segment's growth. Recent product launches have underscored the potential of NK cell-based therapies in oncology. For instance, Fate Therapeutics' FT596 is an off-the-shelf, iPSC-derived NK cell therapy designed to target multiple cancer types, including B-cell malignancies.
Breakup by End User:
- Hospitals
- Research Centers and Institutes
- Others
Currently, research centers and institutes hold the majority of the total market share
Research centers and institutes offer high-quality reagents and technologies that streamline NK cell research, which is increasing the natural killer cells therapeutics market share. For example, Bio-Techne's Cloudz Human NK Cell Expansion Kit allows researchers to expand NK cells ex vivo efficiently.
Breakup by Region:
- North America
- United States
- Canada
- Asia-Pacific
- China
- Japan
- India
- South Korea
- Australia
- Indonesia
- Others
- Europe
- Germany
- France
- United Kingdom
- Italy
- Spain
- Russia
- Others
- Latin America
- Brazil
- Mexico
- Others
- Middle East and Africa
North America exhibits a clear dominance in the market
The market research report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, North America accounted for the largest market share.
Advancements in biotechnology and a strong focus on innovative cancer treatments are primarily catalyzing the market in North America. According to the IMARC, the United States cancer immunotherapy market size is projected to exhibit a growth rate (CAGR) of 10.90% during 2024-2032. Besides this, collaborations between biotech firms are strengthening the regional market.
Competitive Landscape:
The market research report has provided a comprehensive analysis of the competitive landscape. Detailed profiles of all major market companies have also been provided. Some of the key players in the market include:
- Affimed GmbH
- Bristol-Myers Squibb Company
- Fate Therapeutics
- Fortress Biotech Inc.
- Glycostem Therapeutics
- Innate Pharma S.A.
- Kuur Therapeutics Inc. (Athenex Inc.)
- Nkarta Inc.
- Takeda Pharmaceutical Company Limited
- Ziopharm Oncology Inc.
Key Questions Answered in This Report
- 1.What was the size of the global natural killer cells therapeutics market in 2024?
- 2.What is the expected growth rate of the global natural killer cells therapeutics market during 2025-2033?
- 3.What are the key factors driving the global natural killer cells therapeutics market?
- 4.What has been the impact of COVID-19 on the global natural killer cells therapeutics market?
- 5.What is the breakup of the global natural killer cells therapeutics market based on the therapeutics?
- 6.What is the breakup of the global natural killer cells therapeutics market based on the application?
- 7.What is the breakup of the global natural killer cells therapeutics market based on the end user?
- 8.What are the key regions in the global natural killer cells therapeutics market?
- 9.Who are the key players/companies in the global natural killer cells therapeutics market?
Table of Contents
1 Preface
2 Scope and Methodology
- 2.1 Objectives of the Study
- 2.2 Stakeholders
- 2.3 Data Sources
- 2.3.1 Primary Sources
- 2.3.2 Secondary Sources
- 2.4 Market Estimation
- 2.4.1 Bottom-Up Approach
- 2.4.2 Top-Down Approach
- 2.5 Forecasting Methodology
3 Executive Summary
4 Introduction
- 4.1 Overview
- 4.2 Key Industry Trends
5 Global Natural Killer Cells Therapeutics Market
- 5.1 Market Overview
- 5.2 Market Performance
- 5.3 Impact of COVID-19
- 5.4 Market Forecast
6 Market Breakup by Therapeutics
- 6.1 NK Cell Therapies
- 6.1.1 Market Trends
- 6.1.2 Market Forecast
- 6.2 NK Cell Directed Antibodies
- 6.2.1 Market Trends
- 6.2.2 Market Forecast
7 Market Breakup by Application
- 7.1 Cancer
- 7.1.1 Market Trends
- 7.1.2 Market Forecast
- 7.2 Gastrointestinal Diseases
- 7.2.1 Market Trends
- 7.2.2 Market Forecast
- 7.3 Immunoproliferative Disorders
- 7.3.1 Market Trends
- 7.3.2 Market Forecast
- 7.4 Others
- 7.4.1 Market Trends
- 7.4.2 Market Forecast
8 Market Breakup by End User
- 8.1 Hospitals
- 8.1.1 Market Trends
- 8.1.2 Market Forecast
- 8.2 Research Centers and Institutes
- 8.2.1 Market Trends
- 8.2.2 Market Forecast
- 8.3 Others
- 8.3.1 Market Trends
- 8.3.2 Market Forecast
9 Market Breakup by Region
- 9.1 North America
- 9.1.1 United States
- 9.1.1.1 Market Trends
- 9.1.1.2 Market Forecast
- 9.1.2 Canada
- 9.1.2.1 Market Trends
- 9.1.2.2 Market Forecast
- 9.1.1 United States
- 9.2 Asia-Pacific
- 9.2.1 China
- 9.2.1.1 Market Trends
- 9.2.1.2 Market Forecast
- 9.2.2 Japan
- 9.2.2.1 Market Trends
- 9.2.2.2 Market Forecast
- 9.2.3 India
- 9.2.3.1 Market Trends
- 9.2.3.2 Market Forecast
- 9.2.4 South Korea
- 9.2.4.1 Market Trends
- 9.2.4.2 Market Forecast
- 9.2.5 Australia
- 9.2.5.1 Market Trends
- 9.2.5.2 Market Forecast
- 9.2.6 Indonesia
- 9.2.6.1 Market Trends
- 9.2.6.2 Market Forecast
- 9.2.7 Others
- 9.2.7.1 Market Trends
- 9.2.7.2 Market Forecast
- 9.2.1 China
- 9.3 Europe
- 9.3.1 Germany
- 9.3.1.1 Market Trends
- 9.3.1.2 Market Forecast
- 9.3.2 France
- 9.3.2.1 Market Trends
- 9.3.2.2 Market Forecast
- 9.3.3 United Kingdom
- 9.3.3.1 Market Trends
- 9.3.3.2 Market Forecast
- 9.3.4 Italy
- 9.3.4.1 Market Trends
- 9.3.4.2 Market Forecast
- 9.3.5 Spain
- 9.3.5.1 Market Trends
- 9.3.5.2 Market Forecast
- 9.3.6 Russia
- 9.3.6.1 Market Trends
- 9.3.6.2 Market Forecast
- 9.3.7 Others
- 9.3.7.1 Market Trends
- 9.3.7.2 Market Forecast
- 9.3.1 Germany
- 9.4 Latin America
- 9.4.1 Brazil
- 9.4.1.1 Market Trends
- 9.4.1.2 Market Forecast
- 9.4.2 Mexico
- 9.4.2.1 Market Trends
- 9.4.2.2 Market Forecast
- 9.4.3 Others
- 9.4.3.1 Market Trends
- 9.4.3.2 Market Forecast
- 9.4.1 Brazil
- 9.5 Middle East and Africa
- 9.5.1 Market Trends
- 9.5.2 Market Breakup by Country
- 9.5.3 Market Forecast
10 SWOT Analysis
- 10.1 Overview
- 10.2 Strengths
- 10.3 Weaknesses
- 10.4 Opportunities
- 10.5 Threats
11 Value Chain Analysis
12 Porters Five Forces Analysis
- 12.1 Overview
- 12.2 Bargaining Power of Buyers
- 12.3 Bargaining Power of Suppliers
- 12.4 Degree of Competition
- 12.5 Threat of New Entrants
- 12.6 Threat of Substitutes
13 Price Analysis
14 Competitive Landscape
- 14.1 Market Structure
- 14.2 Key Players
- 14.3 Profiles of Key Players
- 14.3.1 Affimed GmbH
- 14.3.1.1 Company Overview
- 14.3.1.2 Product Portfolio
- 14.3.1.3 Financials
- 14.3.2 Bristol-Myers Squibb Company
- 14.3.2.1 Company Overview
- 14.3.2.2 Product Portfolio
- 14.3.2.3 Financials
- 14.3.2.4 SWOT Analysis
- 14.3.3 Fate Therapeutics
- 14.3.3.1 Company Overview
- 14.3.3.2 Product Portfolio
- 14.3.3.3 Financials
- 14.3.4 Fortress Biotech Inc.
- 14.3.4.1 Company Overview
- 14.3.4.2 Product Portfolio
- 14.3.4.3 Financials
- 14.3.5 Glycostem Therapeutics
- 14.3.5.1 Company Overview
- 14.3.5.2 Product Portfolio
- 14.3.6 Innate Pharma S.A.
- 14.3.6.1 Company Overview
- 14.3.6.2 Product Portfolio
- 14.3.6.3 Financials
- 14.3.7 Kuur Therapeutics Inc. (Athenex Inc.)
- 14.3.7.1 Company Overview
- 14.3.7.2 Product Portfolio
- 14.3.8 Nkarta Inc.
- 14.3.8.1 Company Overview
- 14.3.8.2 Product Portfolio
- 14.3.8.3 Financials
- 14.3.9 Takeda Pharmaceutical Company Limited
- 14.3.9.1 Company Overview
- 14.3.9.2 Product Portfolio
- 14.3.9.3 Financials
- 14.3.9.4 SWOT Analysis
- 14.3.10 Ziopharm Oncology Inc.
- 14.3.10.1 Company Overview
- 14.3.10.2 Product Portfolio
- 14.3.10.3 Financials
- 14.3.1 Affimed GmbH
List of Figures
- Figure 1: Global: Natural Killer Cells Therapeutics Market: Major Drivers and Challenges
- Figure 2: Global: Natural Killer Cells Therapeutics Market: Sales Value (in Billion USD), 2019-2024
- Figure 3: Global: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Billion USD), 2025-2033
- Figure 4: Global: Natural Killer Cells Therapeutics Market: Breakup by Therapeutics (in %), 2024
- Figure 5: Global: Natural Killer Cells Therapeutics Market: Breakup by Application (in %), 2024
- Figure 6: Global: Natural Killer Cells Therapeutics Market: Breakup by End User (in %), 2024
- Figure 7: Global: Natural Killer Cells Therapeutics Market: Breakup by Region (in %), 2024
- Figure 8: Global: Natural Killer Cells Therapeutics (NK Cell Therapies) Market: Sales Value (in Million USD), 2019 & 2024
- Figure 9: Global: Natural Killer Cells Therapeutics (NK Cell Therapies) Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 10: Global: Natural Killer Cells Therapeutics (NK Cell Directed Antibodies) Market: Sales Value (in Million USD), 2019 & 2024
- Figure 11: Global: Natural Killer Cells Therapeutics (NK Cell Directed Antibodies) Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 12: Global: Natural Killer Cells Therapeutics (Cancer) Market: Sales Value (in Million USD), 2019 & 2024
- Figure 13: Global: Natural Killer Cells Therapeutics (Cancer) Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 14: Global: Natural Killer Cells Therapeutics (Gastrointestinal Diseases) Market: Sales Value (in Million USD), 2019 & 2024
- Figure 15: Global: Natural Killer Cells Therapeutics (Gastrointestinal Diseases) Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 16: Global: Natural Killer Cells Therapeutics (Immunoproliferative Disorders) Market: Sales Value (in Million USD), 2019 & 2024
- Figure 17: Global: Natural Killer Cells Therapeutics (Immunoproliferative Disorders) Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 18: Global: Natural Killer Cells Therapeutics (Other Applications) Market: Sales Value (in Million USD), 2019 & 2024
- Figure 19: Global: Natural Killer Cells Therapeutics (Other Applications) Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 20: Global: Natural Killer Cells Therapeutics (Hospitals) Market: Sales Value (in Million USD), 2019 & 2024
- Figure 21: Global: Natural Killer Cells Therapeutics (Hospitals) Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 22: Global: Natural Killer Cells Therapeutics (Research Centers and Institutes ) Market: Sales Value (in Million USD), 2019 & 2024
- Figure 23: Global: Natural Killer Cells Therapeutics (Research Centers and Institutes ) Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 24: Global: Natural Killer Cells Therapeutics (Other End Users) Market: Sales Value (in Million USD), 2019 & 2024
- Figure 25: Global: Natural Killer Cells Therapeutics (Other End Users) Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 26: North America: Natural Killer Cells Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
- Figure 27: North America: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 28: United States: Natural Killer Cells Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
- Figure 29: United States: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 30: Canada: Natural Killer Cells Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
- Figure 31: Canada: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 32: Asia-Pacific: Natural Killer Cells Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
- Figure 33: Asia-Pacific: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 34: China: Natural Killer Cells Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
- Figure 35: China: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 36: Japan: Natural Killer Cells Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
- Figure 37: Japan: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 38: India: Natural Killer Cells Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
- Figure 39: India: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 40: South Korea: Natural Killer Cells Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
- Figure 41: South Korea: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 42: Australia: Natural Killer Cells Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
- Figure 43: Australia: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 44: Indonesia: Natural Killer Cells Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
- Figure 45: Indonesia: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 46: Others: Natural Killer Cells Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
- Figure 47: Others: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 48: Europe: Natural Killer Cells Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
- Figure 49: Europe: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 50: Germany: Natural Killer Cells Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
- Figure 51: Germany: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 52: France: Natural Killer Cells Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
- Figure 53: France: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 54: United Kingdom: Natural Killer Cells Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
- Figure 55: United Kingdom: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 56: Italy: Natural Killer Cells Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
- Figure 57: Italy: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 58: Spain: Natural Killer Cells Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
- Figure 59: Spain: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 60: Russia: Natural Killer Cells Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
- Figure 61: Russia: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 62: Others: Natural Killer Cells Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
- Figure 63: Others: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 64: Latin America: Natural Killer Cells Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
- Figure 65: Latin America: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 66: Brazil: Natural Killer Cells Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
- Figure 67: Brazil: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 68: Mexico: Natural Killer Cells Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
- Figure 69: Mexico: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 70: Others: Natural Killer Cells Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
- Figure 71: Others: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 72: Middle East and Africa: Natural Killer Cells Therapeutics Market: Sales Value (in Million USD), 2019 & 2024
- Figure 73: Middle East and Africa: Natural Killer Cells Therapeutics Market: Breakup by Country (in %), 2024
- Figure 74: Middle East and Africa: Natural Killer Cells Therapeutics Market Forecast: Sales Value (in Million USD), 2025-2033
- Figure 75: Global: Natural Killer Cells Therapeutics Industry: SWOT Analysis
- Figure 76: Global: Natural Killer Cells Therapeutics Industry: Value Chain Analysis
- Figure 77: Global: Natural Killer Cells Therapeutics Industry: Porter's Five Forces Analysis
List of Tables
- Table 1: Global: Natural Killer Cells Therapeutics Market: Key Industry Highlights, 2024 and 2033
- Table 2: Global: Natural Killer Cells Therapeutics Market Forecast: Breakup by Therapeutics (in Million USD), 2025-2033
- Table 3: Global: Natural Killer Cells Therapeutics Market Forecast: Breakup by Application (in Million USD), 2025-2033
- Table 4: Global: Natural Killer Cells Therapeutics Market Forecast: Breakup by End User (in Million USD), 2025-2033
- Table 5: Global: Natural Killer Cells Therapeutics Market Forecast: Breakup by Region (in Million USD), 2025-2033
- Table 6: Global: Natural Killer Cells Therapeutics Market: Competitive Structure
- Table 7: Global: Natural Killer Cells Therapeutics Market: Key Players
