Base Editing Market by Component, Type, Technique, Application, End-use

List of Tables

[181 Pages Report] The Base Editing Market size was estimated at USD 277.65 million in 2023 and expected to reach USD 319.93 million in 2024, at a CAGR 16.01% to reach USD 785.47 million by 2030.

Global Base Editing Market

KEY MARKET STATISTICS
Base Year [2023]	USD 277.65 million
Estimated Year [2024]	USD 319.93 million
Forecast Year [2030]	USD 785.47 million
CAGR (%)	16.01%

Base Editing is a form of precision genome editing technique that enables the direct, irreversible conversion of one DNA base pair into another at a specific location in the genome without requiring a double-stranded DNA break or a donor DNA template. This innovative approach uses a fusion protein consisting of a catalytically disabled CRISPR-Cas9 linked to a base deaminase enzyme. By targeting the desired genomic loci with guide RNA, base editors can induce point mutations by chemically modifying the DNA bases, leading to a base pair substitution after DNA replication. This technique offers potential applications in therapeutic gene editing, research on disease genetics, and the development of new agricultural products. This market includes the development and sales of base editing tools, services, consumables, and various applications in therapeutic development, agriculture, and biotechnology research. The applications of base editing are vast and varied. In the therapeutic space, base editing is used to correct single-point mutations that cause genetic diseases. Base editing can develop crops with beneficial traits such as disease resistance or increased yield in agriculture. For research and development, it is an invaluable tool for understanding gene function and creating models of human disease. The market scope for base editing includes pharmaceutical companies developing gene therapies, agricultural biotechnology firms, and academic and research institutions. Key factors influencing the growth of base editing include rising government funding and growing focus on genomic studies, expanding the application of genomics in the pharmaceutical sector, and increasing prevalence of rare diseases. Additionally, strategic collaborations among biotech firms and research organizations fuel market expansion. However, the base editing market faces several limitations and challenges, such as issues associated with ethics and safety and stringent regulations regarding base editing. On the other hand, the expanding application of base editing in the agricultural sector and increasing preference for personalized medicine worldwide present opportunities for expanding base editing.

Regional Insights

In North America, the United States and Canada are at the forefront of base editing research and applications, with the presence of major biotechnology companies, heavy investments in gene editing technologies, and a favorable regulatory environment contributing to the rapid adoption of base editing. Partnerships between academic institutions and biotech firms are fueling innovation, with an emphasis on therapeutic applications to treat genetic disorders. South America has shown an increased interest in base editing, particularly in the areas of agriculture and crop improvement. Countries such as Brazil and Argentina are investing in biotechnology to bolster their vast agricultural sectors, using base editing to enhance crop resilience and productivity. The APAC region is experiencing substantial growth in the base editing market due to the rise in genetic research and increased investments in biotechnology. Countries such as China and Japan are at the forefront, with China leading in research output and patented technologies. China, in particular, has made headlines with significant advancements in gene editing and is actively implementing base editing in clinical research. Japan is notable for its precise regulatory framework, which balances innovation with ethical considerations. Europe boasts a strong pharmaceutical industry and a robust research environment, which propels the adoption of base editing technology. With the European Union's active support for gene editing research through various funding initiatives, several European countries are making notable contributions to the field. The Middle East has seen increased investment in healthcare innovation, particularly in nations such as Saudi Arabia and the United Arab Emirates, where base editing is emerging as a tool for medical research and potential treatments. In Africa, while the technology is still developing, it has the prospect of addressing critical challenges in healthcare and agriculture. Capacity building through international partnerships and educational initiatives is essential for the expansion of base editing in the region.

FPNV Positioning Matrix

The FPNV Positioning Matrix is pivotal in evaluating the Base Editing Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).

Market Share Analysis

The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the Base Editing Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.

Key Company Profiles

The report delves into recent significant developments in the Base Editing Market, highlighting leading vendors and their innovative profiles. These include Addgene, Inc., Beam Therapeutics, Beijing Qi Biodesign Biotechnology Company Limited, Bio Palette Co., Ltd., Creative Biogene, DH Life Sciences, LLC, Editas Medicine, Inc., ElevateBio, LLC, GenScript Biotech Corporation, Intellia Therapeutics, Inc., KromaTiD Inc., Pairwise Plants Services, ProQR Therapeutics N.V., QIAGEN GmbH, Revvity, Inc., Sangamo Therapeutics, Inc., Synthego Corporation, Tecan Group, and TriLink BioTechnologies by Maravai LifeSciences.

Market Segmentation & Coverage

This research report categorizes the Base Editing Market to forecast the revenues and analyze trends in each of the following sub-markets:

Component
- Consumables
  - Base Editing Libraries
  - Kits & Reagents
  - Plasmids
- Services
  - Cell Line Engineering
  - gRNA Design
Type
- DNA Base Editing
- RNA Base Editing
Technique
- CRISPR-Cas9
- TALE Nucleases
- Zinc-Finger Nucleases
Application
- Human Therapeutics
- Livestock
- Plant Breeding
End-use
- Academic & Research Institutes
- Contract Research Organizations
- Pharmaceutical & Biotechnology Companies
Region
- Americas
  - Argentina
  - Brazil
  - Canada
  - Mexico
  - United States
    - California
    - Florida
    - Illinois
    - New York
    - Ohio
    - Pennsylvania
    - Texas
- Asia-Pacific
  - Australia
  - China
  - India
  - Indonesia
  - Japan
  - Malaysia
  - Philippines
  - Singapore
  - South Korea
  - Taiwan
  - Thailand
  - Vietnam
- Europe, Middle East & Africa
  - Denmark
  - Egypt
  - Finland
  - France
  - Germany
  - Israel
  - Italy
  - Netherlands
  - Nigeria
  - Norway
  - Poland
  - Qatar
  - Russia
  - Saudi Arabia
  - South Africa
  - Spain
  - Sweden
  - Switzerland
  - Turkey
  - United Arab Emirates
  - United Kingdom

The report offers valuable insights on the following aspects:

1. Market Penetration: It presents comprehensive information on the market provided by key players.

2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.

3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.

4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.

5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.

The report addresses key questions such as:

1. What is the market size and forecast of the Base Editing Market?

2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the Base Editing Market?

3. What are the technology trends and regulatory frameworks in the Base Editing Market?

4. What is the market share of the leading vendors in the Base Editing Market?

5. Which modes and strategic moves are suitable for entering the Base Editing Market?

Product Code: MRR-F3183FD145E3

1. Preface

1.1. Objectives of the Study
1.2. Market Segmentation & Coverage
1.3. Years Considered for the Study
1.4. Currency & Pricing
1.5. Language
1.6. Limitations
1.7. Assumptions
1.8. Stakeholders

2. Research Methodology

2.1. Define: Research Objective
2.2. Determine: Research Design
2.3. Prepare: Research Instrument
2.4. Collect: Data Source
2.5. Analyze: Data Interpretation
2.6. Formulate: Data Verification
2.7. Publish: Research Report
2.8. Repeat: Report Update

3. Executive Summary

4. Market Overview

4.1. Introduction
4.2. Base Editing Market, by Region

5. Market Insights

5.1. Market Dynamics
- 5.1.1. Drivers
  - 5.1.1.1. Rising government funding and growing focus on genomic studies
  - 5.1.1.2. Expanding the application of genomics in pharmaceutical sector
  - 5.1.1.3. Increasing prevalence of rare diseases
- 5.1.2. Restraints
  - 5.1.2.1. Issues associated with ethics and safety
- 5.1.3. Opportunities
  - 5.1.3.1. Expanding application of base editing in the agricultural sector
  - 5.1.3.2. Increasing preference for personalized medicine worldwide
- 5.1.4. Challenges
  - 5.1.4.1. Stringent regulations regarding base editing
5.2. Market Segmentation Analysis
- 5.2.1. Component: Increasing preference for base editing services for external services
- 5.2.2. Type: Expanding usage of DNA base editing for high precision
- 5.2.3. Application: Growing application of base editing for drug discovery & development
- 5.2.4. End-use: Growing adoption of base editing in academic & research institutes
5.3. Market Trend Analysis
5.4. Cumulative Impact of High Inflation
5.5. Porter's Five Forces Analysis
- 5.5.1. Threat of New Entrants
- 5.5.2. Threat of Substitutes
- 5.5.3. Bargaining Power of Customers
- 5.5.4. Bargaining Power of Suppliers
- 5.5.5. Industry Rivalry
5.6. Value Chain & Critical Path Analysis
5.7. Regulatory Framework

6. Base Editing Market, by Component

6.1. Introduction
6.2. Consumables
- 6.3.1. Base Editing Libraries
- 6.3.2. Kits & Reagents
- 6.3.3. Plasmids
6.3. Services
- 6.4.1. Cell Line Engineering
- 6.4.2. gRNA Design

7. Base Editing Market, by Type

7.1. Introduction
7.2. DNA Base Editing
7.3. RNA Base Editing

8. Base Editing Market, by Technique

8.1. Introduction
8.2. CRISPR-Cas9
8.3. TALE Nucleases
8.4. Zinc-Finger Nucleases

9. Base Editing Market, by Application

9.1. Introduction
9.2. Human Therapeutics
9.3. Livestock
9.4. Plant Breeding

10. Base Editing Market, by End-use

10.1. Introduction
10.2. Academic & Research Institutes
10.3. Contract Research Organizations
10.4. Pharmaceutical & Biotechnology Companies

11. Americas Base Editing Market

11.1. Introduction
11.2. Argentina
11.3. Brazil
11.4. Canada
11.5. Mexico
11.6. United States

12. Asia-Pacific Base Editing Market

12.1. Introduction
12.2. Australia
12.3. China
12.4. India
12.5. Indonesia
12.6. Japan
12.7. Malaysia
12.8. Philippines
12.9. Singapore
12.10. South Korea
12.11. Taiwan
12.12. Thailand
12.13. Vietnam

13. Europe, Middle East & Africa Base Editing Market

13.1. Introduction
13.2. Denmark
13.3. Egypt
13.4. Finland
13.5. France
13.6. Germany
13.7. Israel
13.8. Italy
13.9. Netherlands
13.10. Nigeria
13.11. Norway
13.12. Poland
13.13. Qatar
13.14. Russia
13.15. Saudi Arabia
13.16. South Africa
13.17. Spain
13.18. Sweden
13.19. Switzerland
13.20. Turkey
13.21. United Arab Emirates
13.22. United Kingdom

14. Competitive Landscape

14.1. FPNV Positioning Matrix
14.2. Market Share Analysis, By Key Player
14.3. Competitive Scenario Analysis, By Key Player
- 14.3.1. Merger & Acquisition
  - 14.3.1.1. Beam Announces Agreement for Lilly to Acquire Beam's Opt-In Rights to Verve Therapeutics' Base Editing Programs for Cardiovascular Disease
- 14.3.2. Agreement, Collaboration, & Partnership
  - 14.3.2.1. Pfizer and Beam Enter Exclusive Multi-Target Research Collaboration to Advance Novel In Vivo Base Editing Programs for a Range of Rare Diseases
- 14.3.3. New Product Launch & Enhancement
  - 14.3.3.1. Revvity Expands Access to Base Editing Technology With Aim to Accelerate Discovery to Cure
  - 14.3.3.2. Researchers develop new base editing tools using AI-predicted protein structure clustering

15. Competitive Portfolio

15.1. Key Company Profiles
- 15.1.1. Addgene, Inc.
- 15.1.2. Beam Therapeutics
- 15.1.3. Beijing Qi Biodesign Biotechnology Company Limited
- 15.1.4. Bio Palette Co., Ltd.
- 15.1.5. Creative Biogene
- 15.1.6. DH Life Sciences, LLC
- 15.1.7. Editas Medicine, Inc.
- 15.1.8. ElevateBio, LLC
- 15.1.9. GenScript Biotech Corporation
- 15.1.10. Intellia Therapeutics, Inc.
- 15.1.11. KromaTiD Inc.
- 15.1.12. Pairwise Plants Services
- 15.1.13. ProQR Therapeutics N.V.
- 15.1.14. QIAGEN GmbH
- 15.1.15. Revvity, Inc.
- 15.1.16. Sangamo Therapeutics, Inc.
- 15.1.17. Synthego Corporation
- 15.1.18. Tecan Group
- 15.1.19. TriLink BioTechnologies by Maravai LifeSciences
15.2. Key Product Portfolio

16. Appendix

16.1. Discussion Guide
16.2. License & Pricing