Extracorporeal Membrane Oxygenation Machine Market by Modality, Age, Component, Application, End-User

Description

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[198 Pages Report] The Extracorporeal Membrane Oxygenation Machine Market size was estimated at USD 794.86 million in 2023 and expected to reach USD 832.14 million in 2024, at a CAGR 4.55% to reach USD 1,085.63 million by 2030.

Extracorporeal membrane oxygenation machines are medical devices that provide prolonged cardiac & respiratory support for patients whose hearts and lungs cannot provide adequate gas exchange to sustain life. These machines extract blood from the patient's body, oxygenate it through an artificial lung (the membrane), remove carbon dioxide, and then return it to the patient's bloodstream. This external life support system takes over the function of the heart and lungs, allowing these organs to rest and heal during critical illness. The surging prevalence of cardiovascular and respiratory diseases and technological advancements that improve patient outcomes have increased the adoption of ECMO systems. Additionally, improvements in healthcare infrastructure and increased healthcare spending are contributing to the market expansion. High costs associated with ECMO procedures and a limited number of trained healthcare professionals to operate these machines represent a challenge for market growth. Nevertheless, advancements in ECMO machine design to enhance portability and ease of use in different treatment settings are expected to provide opportunistic scope for the market. Moreover, ECMO integration with other extracorporeal therapies and research activities focused on expanding the indications for ECMO support is expected to boost the market.

KEY MARKET STATISTICS
Base Year [2023]	USD 794.86 million
Estimated Year [2024]	USD 832.14 million
Forecast Year [2030]	USD 1,085.63 million
CAGR (%)	4.55%

Modality: Rising utilization of venoarterial ECMO as it provides both cardiac and respiratory support

Arteriovenous extracorporeal membrane oxygenation (AV ECMO) is an older method of ECMO support that utilizes the patient's arterial and venous blood flow to drive blood through the ECMO circuit. In AV ECMO, blood is drawn from an artery and returned to a vein after oxygenation. This technique relies on the patient's heart to pump blood through the oxygenator. It is less commonly used in modern ECMO therapy due to advancements in technology that prefer other modes for efficiency and safety. Venoarterial extracorporeal membrane oxygenation (VA ECMO) provides both cardiac and respiratory support by withdrawing venous blood, which is then oxygenated outside of the body and infused back into an artery. VA ECMO is used in cases of severe heart failure or cardiac arrest because it bypasses both the heart and the lungs, thus providing full support to these organs. The cannulation is usually done through the large central vessels, such as the femoral or carotid artery and vein. VA ECMO is utilized primarily for respiratory support, where blood is removed from a large vein, oxygenated through the ECMO circuit, and returned to a vein. This mode of ECMO ensures adequate oxygenation when the lungs are severely compromised by conditions including acute respiratory distress syndrome (ARDS) or pneumonia. The typical cannulation sites for VV ECMO include the internal jugular and femoral veins.

Age: Increasing need for ECMO machines in adults owing to respiratory & cardiac disorders

Adult patients who require ECMO therapy suffer from severe respiratory or cardiac conditions that are unresponsive to conventional management. These include conditions such as acute respiratory distress syndrome (ARDS), cardiogenic shock, or pulmonary embolism. Adult ECMO machines are designed to manage larger blood flow with durable components that can withstand extended use. Neonates require ECMO support due to conditions present at birth, such as congenital diaphragmatic hernia or meconium aspiration syndrome. Neonatal ECMO machines are designed to handle the delicate and minimal blood volume of newborns with precise control and gentle flow to minimize the risk of hemolysis or other blood-related complications. The primary distinction for neonatal ECMO machines is the focus on reducing invasiveness and limiting the extracorporeal circuit volume to suit the patient's size. The machines also have smaller cannulae and specialized circuits than those used for older children and adults. Pediatric patients, ranging from infants to older children, may require ECMO due to various respiratory and cardiac failures that are unresponsive to standard treatment. Pediatric ECMO machines must be versatile to accommodate the wide age and size range of patients in this group, with adjustability in flow rates and oxygenator sizes.

Component: Increasing need for durable and biocompatible oxygenators for ECMO machines

Anticoagulation systems are integral to the ECMO setup, preventing blood from clotting as it travels outside the body through the ECMO circuit. Blenders in ECMO machines mix air with pure oxygen, delivering controlled oxygen levels to the patient. Blenders must offer adjustable oxygen concentration ranges to cater to varying patient needs. Cannulae are conduits for blood flow between the patient and the ECMO machine, which come in various sizes and materials tailored to specific patient anatomy and surgical requirements. Heat exchangers regulate the blood temperature during ECMO therapy, crucial for maintaining the patient's core temperature. Monitoring systems are critical for overseeing the patient's vitals and the ECMO machine's performance. The oxygenator is the heart of the ECMO machine, where gas exchange occurs. Manufacturers are currently producing oxygenators that maximize gas exchange efficiency while minimizing blood trauma. The pump propels blood through the ECMO circuit, and centrifugal and roller pumps are the two primary pumps in ECMO machines. Centrifugal pumps are preferred for their lower hemolysis rates, while roller pumps are favored for their simplicity and cost-effectiveness.

Application: Proliferating usage of Extracorporeal Cardiopulmonary Resuscitation (ECPR) as it quickly restores oxygenated blood flow to vital organs

ECMO machines are widely used in cardiac applications as a life-supporting bridge for patients experiencing severe heart failure or during high-risk cardiac procedures. When used this way, the ECMO machine takes over the heart's function to oxygenate the blood and sustain systemic circulation, giving the patient's heart time to rest and recover or be repaired. This is particularly crucial during postcardiotomy cardiogenic shock or cardiac transplantation when the heart may not immediately sustain circulation. Extracorporeal Cardiopulmonary Resuscitation (ECPR) is an emerging technique where ECMO is employed alongside conventional CPR in cases of cardiac arrest, especially when the standard resuscitation efforts do not lead to a return of spontaneous circulation. ECPR can quickly restore oxygenated blood flow to vital organs, thus extending the timeframe for successful resuscitation and reducing the risk of neurological damage due to prolonged oxygen deprivation. It represents a valuable option in environments that facilitate rapid deployment, such as in specialized cardiac centers where time-sensitive interventions can be critical to patient survival. In respiratory applications, ECMO is a pivotal treatment modality for patients experiencing severe and potentially reversible respiratory failure that is not responsive to conventional management, including mechanical ventilation. Conditions including acute respiratory distress syndrome (ARDS), severe pneumonia, or pulmonary embolism may warrant the use of ECMO. The ECMO system allows the lungs to rest while minimizing ventilator-induced lung injury by providing adequate oxygenation and removing carbon dioxide. The ECMO system has played a pivotal role in managing critical respiratory conditions, including during outbreaks of infectious diseases such as the H1N1 influenza and COVID-19.

End-User: Development of advanced ECMO machines to cater to dedicated intensive care units in hospitals

Ambulatory surgical centers (ASCs) are healthcare facilities that provide same-day surgical care, including diagnostic and preventive procedures. The preference for ECMO machines in ASCs is based on the need to provide prompt respiratory or cardiac support for high-risk patients during complex surgeries or in the immediate postoperative period. This includes patients anticipated to require only a brief duration of ECMO support or those with specific needs that can be addressed rapidly without an extended hospital stay. Hospitals serve as the primary end-user segment for ECMO machines due to the comprehensive and varied levels of patient care they provide, including intensive care units where ECMO machines are most commonly utilized. Hospitals mainly use ECMO machines for patients requiring extended cardiac and respiratory support that cannot be adequately delivered through conventional ventilation or medication. Hospitals generally have greater infrastructure and resources to manage complex ECMO cases than ASCs or specialty clinics. Specialty clinics are outpatient facilities that focus on specific healthcare services, which may include providing ECMO treatment. Specialty clinics may employ ECMO machines to provide targeted support for patients with complex but stable cardiac or respiratory conditions that do not require the extensive resources of a hospital setting. The preference for ECMO machines in this setting is for a focused approach to treatment, offering advanced care to patients with specific needs.

Regional Insights

In the Americas region, extracorporeal membrane oxygenation machines have seen significant growth driven by the high incidence rates of cardiovascular and respiratory diseases, a well-established healthcare infrastructure system, and the availability of skilled professionals. Additionally, the region has seen a surge in ECMO utilization due to the COVID-19 pandemic, further fueling market expansion. Increased funding for research and development, coupled with technological advancements, continues to enhance ECMO system capabilities, making them more efficient and user-friendly for critical care adoption. The market landscape for ECMO machines in the EMEA region exhibits steady growth. In Europe, the demand for ECMO support is influenced by rising healthcare expenditures, an aging population, and the prevalence of lifestyle-associated diseases. Major economies are implementing ECMOs due to their advanced healthcare systems and policies that favor adopting medical devices. The Asia-Pacific region shows high-growth prospects for ECMO machines. Economic development, increasing healthcare expenditure, and a growing population base are pivotal forces propelling market growth. Major economies are investing heavily in upgrading their healthcare infrastructure. Moreover, the boosting medical tourism industry in some economies is also opening new avenues for the ECMO machines market.

FPNV Positioning Matrix

The FPNV Positioning Matrix is pivotal in evaluating the Extracorporeal Membrane Oxygenation Machine Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).

Market Share Analysis

The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the Extracorporeal Membrane Oxygenation Machine Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.

Key Company Profiles

The report delves into recent significant developments in the Extracorporeal Membrane Oxygenation Machine Market, highlighting leading vendors and their innovative profiles. These include Abbott Laboratories, Abiomed, Inc., Baxter International Inc., Braile Biomedica, Chalice Medical Ltd., CytoSorbents Corporation, Dragerwerk AG & Co. KGaA, Eurosets S.R.L., Getinge AB, Guangdong Pigeon Medical Apparatus Co.,Ltd., Hengko Technology Co., Ltd., Inspira Technologies OXY B.H.N. Ltd., LivaNova PLC, MC3 Cardiopulmonary, Medtronic PLC, MicroPort Scientific Corporation, Nipro Corporation, Origen Biomedical, Inc., Owgels Group, Senko Medical Instrument Mfg. Co., Ltd., Shenzhen Mindray Biomedical Electronics Co. Ltd., Technimount System, Terumo Corporation, XENIOS AG by Fresenius Medical Care AG & Co. KGaA, and ZOLL Medical Corporation by Asahi Kasei Corporation.

Market Segmentation & Coverage

This research report categorizes the Extracorporeal Membrane Oxygenation Machine Market to forecast the revenues and analyze trends in each of the following sub-markets:

Modality
- Arteriovenous ECMO
- Venoarterial ECMO
- Venovenous ECMO

Age
- Adult
- Neonate
- Pediatric

Component
- Anticoagulation Systems
- Blender
- Cannulae
- Heat Exchanger
- Monitoring Systems
- Oxygenator
- Pump

Application
- Cardiac Application
- Extracorporeal Cardiopulmonary Resuscitation
- Respiratory Application

End-User
- Ambulatory Surgical Centers
- Hospitals
- Specialty Clinics

Region
- Americas
  - Argentina
  - Brazil
  - Canada
  - Mexico
  - United States
    - California
    - Florida
    - Illinois
    - New York
    - Ohio
    - Pennsylvania
    - Texas
- Asia-Pacific
  - Australia
  - China
  - India
  - Indonesia
  - Japan
  - Malaysia
  - Philippines
  - Singapore
  - South Korea
  - Taiwan
  - Thailand
  - Vietnam

Europe, Middle East & Africa
- Denmark
- Egypt
- Finland
- France
- Germany
- Israel
- Italy
- Netherlands
- Nigeria
- Norway
- Poland
- Qatar
- Russia
- Saudi Arabia
- South Africa
- Spain
- Sweden
- Switzerland
- Turkey
- United Arab Emirates
- United Kingdom

The report offers valuable insights on the following aspects:

1. Market Penetration: It presents comprehensive information on the market provided by key players.

2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.

3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.

4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.

5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.

The report addresses key questions such as:

1. What is the market size and forecast of the Extracorporeal Membrane Oxygenation Machine Market?

2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the Extracorporeal Membrane Oxygenation Machine Market?

3. What are the technology trends and regulatory frameworks in the Extracorporeal Membrane Oxygenation Machine Market?

4. What is the market share of the leading vendors in the Extracorporeal Membrane Oxygenation Machine Market?

5. Which modes and strategic moves are suitable for entering the Extracorporeal Membrane Oxygenation Machine Market?

Product Code: MRR-03607F65CC95

1. Preface

1.1. Objectives of the Study
1.2. Market Segmentation & Coverage
1.3. Years Considered for the Study
1.4. Currency & Pricing
1.5. Language
1.6. Stakeholders

2. Research Methodology

2.1. Define: Research Objective
2.2. Determine: Research Design
2.3. Prepare: Research Instrument
2.4. Collect: Data Source
2.5. Analyze: Data Interpretation
2.6. Formulate: Data Verification
2.7. Publish: Research Report
2.8. Repeat: Report Update

3. Executive Summary

4. Market Overview

5. Market Insights

5.1. Market Dynamics
- 5.1.1. Drivers
  - 5.1.1.1. Prevalence of cardiovascular and respiratory diseases
  - 5.1.1.2. Adoption of ECMO for neonatal care and expansion of ECMO centers
- 5.1.2. Restraints
  - 5.1.2.1. Adverse recalls of ECMO machines
- 5.1.3. Opportunities
  - 5.1.3.1. Ongoing advancements in ECMO machines
  - 5.1.3.2. Improving reimbursement scenario for ECMO machines worldwide
- 5.1.4. Challenges
  - 5.1.4.1. Potential complexity associated with the operation and maintenance of ECMO
5.2. Market Segmentation Analysis
- 5.2.1. Modality: Rising utilization of venoarterial ECMO as it provides both cardiac and respiratory support
- 5.2.2. Age: Increasing need for ECMO machines in adults owing to respiratory & cardiac disorders
- 5.2.3. Component: Increasing need for durable and biocompatible oxygenators for ECMO machines
- 5.2.4. Application: Proliferating usage of Extracorporeal Cardiopulmonary Resuscitation (ECPR) as it quickly restores oxygenated blood flow to vital organs
- 5.2.5. End-User: Development of advanced ECMO machines to cater to dedicated intensive care units in hospitals
5.3. Market Trend Analysis
- 5.3.1. Established healthcare infrastructure and focused on specialized research efforts across the Americas
- 5.3.2. Increasing deployment of ECMO machines with rising investment for improving healthcare infrastructure across the APAC region
- 5.3.3. Increasing research activities for evaluating effectiveness, coupled with growing ECMO programs and training in the EMEA region
5.4. Cumulative Impact of High Inflation
5.5. Porter's Five Forces Analysis
- 5.5.1. Threat of New Entrants
- 5.5.2. Threat of Substitutes
- 5.5.3. Bargaining Power of Customers
- 5.5.4. Bargaining Power of Suppliers
- 5.5.5. Industry Rivalry
5.6. Value Chain & Critical Path Analysis
5.7. Regulatory Framework Analysis

6. Extracorporeal Membrane Oxygenation Machine Market, by Modality

6.1. Introduction
6.2. Arteriovenous ECMO
6.3. Venoarterial ECMO
6.4. Venovenous ECMO

7. Extracorporeal Membrane Oxygenation Machine Market, by Age

7.1. Introduction
7.2. Adult
7.3. Neonate
7.4. Pediatric

8. Extracorporeal Membrane Oxygenation Machine Market, by Component

8.1. Introduction
8.2. Anticoagulation Systems
8.3. Blender
8.4. Cannulae
8.5. Heat Exchanger
8.6. Monitoring Systems
8.7. Oxygenator
8.8. Pump

9. Extracorporeal Membrane Oxygenation Machine Market, by Application

9.1. Introduction
9.2. Cardiac Application
9.3. Extracorporeal Cardiopulmonary Resuscitation
9.4. Respiratory Application

10. Extracorporeal Membrane Oxygenation Machine Market, by End-User

10.1. Introduction
10.2. Ambulatory Surgical Centers
10.3. Hospitals
10.4. Specialty Clinics

11. Americas Extracorporeal Membrane Oxygenation Machine Market

11.1. Introduction
11.2. Argentina
11.3. Brazil
11.4. Canada
11.5. Mexico
11.6. United States

12. Asia-Pacific Extracorporeal Membrane Oxygenation Machine Market

12.1. Introduction
12.2. Australia
12.3. China
12.4. India
12.5. Indonesia
12.6. Japan
12.7. Malaysia
12.8. Philippines
12.9. Singapore
12.10. South Korea
12.11. Taiwan
12.12. Thailand
12.13. Vietnam

13. Europe, Middle East & Africa Extracorporeal Membrane Oxygenation Machine Market

13.1. Introduction
13.2. Denmark
13.3. Egypt
13.4. Finland
13.5. France
13.6. Germany
13.7. Israel
13.8. Italy
13.9. Netherlands
13.10. Nigeria
13.11. Norway
13.12. Poland
13.13. Qatar
13.14. Russia
13.15. Saudi Arabia
13.16. South Africa
13.17. Spain
13.18. Sweden
13.19. Switzerland
13.20. Turkey
13.21. United Arab Emirates
13.22. United Kingdom

14. Competitive Landscape

14.1. Market Share Analysis, 2023
14.2. FPNV Positioning Matrix, 2023
14.3. Competitive Scenario Analysis
- 14.3.1. The Government of New South Wales (NSW)'s New Innovative Clinical Trial with Mobile Cardiac Treatment
- 14.3.2. Inspira Technologies Unveils the INSPIRA ART Line of Medical Devices at the World's Largest Extracorporeal Life Support Conference
- 14.3.3. AIIMS-R Starts ECMO Treatment
- 14.3.4. MGM Healthcare Inaugurates Advanced ECMO Care Facility for Children
- 14.3.5. Abbott's Life Support System Receives New FDA Clearances to Help Doctors Treat More Critically Ill Patients
- 14.3.6. First Domestic ECMO Machine to Play Vital Role
- 14.3.7. China Grants Market Approval to Self-Developed ECMO Device for Severe COVID-19 Cases

15. Competitive Portfolio

15.1. Key Company Profiles
15.2. Key Product Portfolio