Digital PCR & Real-Time PCR Market by Type, Product Type, Application, End-User

Description

List of Tables

[194 Pages Report] The Digital PCR & Real-Time PCR Market size was estimated at USD 8.24 billion in 2023 and expected to reach USD 8.87 billion in 2024, at a CAGR 7.98% to reach USD 14.11 billion by 2030.

Digital PCR (dPCR) and real-time PCR, often referred to as quantitative PCR (qPCR), are two pivotal techniques bodied under the broader field of polymerase chain reaction (PCR) science. Digital PCR (dPCR) is an advanced molecular biology technique for the absolute quantification of nucleic acids, which includes subdividing the sample into many individual, smaller reactions that contain either zero or one template molecule. Real-Time PCR, known as quantitative PCR (qPCR), differs from standard PCR by enabling the detection of the accumulation of amplification product reaction as it occurs in real-time. These techniques are in high demand owing to their heightened precision and sensitivity for detecting low-level pathogens and rare genetic sequences. The surge in the need for early and precise diagnosis and an uptick in genetic disorders and infectious diseases has led to the growth of the digital PCR & real-time PCR market. Further, the COVID-19 pandemic particularly highlighted the critical role of PCR-based diagnostics in managing infectious outbreaks. Despite its growth, the digital PCR & real-time PCR market contend with limitations, including the variability in the size and shape of droplets, which affect the robustness of the method and the need for specialized expertise in developing economies. However, growing investments by industry participants in R&D and the emergence of droplet digital PCR (ddPCR) technology for exquisite precision and sensitivity promise future prospects for the digital PCR & real-time PCR market growth.

KEY MARKET STATISTICS
Base Year [2023]	USD 8.24 billion
Estimated Year [2024]	USD 8.87 billion
Forecast Year [2030]	USD 14.11 billion
CAGR (%)	7.98%

Type: Higher preferences for qPCR for high throughput and a broader dynamic range

Digital PCR allows absolute quantification of nucleic acids by partitioning the sample into thousands of separate reactions, with each containing zero, one, or a few template molecules. Post PCR, the number of partitions containing amplified DNA is counted, providing direct and precise quantification without the need for standard curves or reference samples. Real-time PCR, often referred to as quantitative PCR or qPCR, is a technology widely used in molecular biology to amplify and simultaneously quantify a targeted DNA molecule. A key feature of qPCR is the use of fluorescent dyes or probes, which bind to the DNA and allow quantification as the reaction progresses.

Product Type: Growing demand for application-specific kits that address the needs of specialized end-users

Within the digital PCR & real-time PCR market, instruments are the vital products that enable researchers to amplify DNA and RNA for various applications. Sample partitioning systems are used to divide the sample into thousands of separate, small droplets. Whereas, thermal cyclers are deployed to amplify segments of the sample via the polymerase chain reaction, and plate sealers are used to seal PCR plates to minimize sample evaporation during amplification. Reagents and consumables represent a critical segment of digital PCR & real-time PCR technologies, encompassing all necessary chemicals and disposable materials used in these workflows. This includes a variety of enzymes, primers, buffers, and master mixes tailored for dPCR and qPCR applications. The quality of these reagents directly impacts the accuracy, sensitivity, and repeatability of dPCR and qPCR techniques. Likewise, the consumables, such as PCR tubes, plates, and seals, are designed to ensure compatibility with different dPCR and qPCR instruments while preventing cross-contamination and sample loss and are essential for the day-to-day operation of any laboratory engaged in molecular testing. The digital PCR & real-time PCR market is complemented by an array of services that cater to customers' diverse needs, from development, validation, and sample testing. Outsourcing dPCR and qPCR services minimizes upfront costs of laboratory setup for end-users while facilitating the development of customized solutions from authorized and expert service providers.

Application: Higher potential in forensics for paternity testing and the detection of low-level DNA in crime scene investigations

In the realm of clinical research, both digital PCR (dPCR) and real-time PCR (qPCR) serve critical roles in advancing our understanding and treatment of diseases. These techniques are particularly adopted for their high precision and ability, making them valuable for detecting rare mutations, copy number variations, and monitoring minimal residual disease. Further, their rapid and reliable quantification of gene expression helps with disease stratification, monitoring treatment efficacy, and validating biomarkers for disease progression and therapeutic response. Forensic laboratories rely heavily on the specificity and sensitivity of qPCR for DNA profiling, detecting minute traces of genetic material, and quantifying DNA prior to sequencing. The advent of dPCR and qPCR has further refined forensic analysis, enhancing the detection of low-level pathogens and analysis of mixed DNA samples. At research institutes, dPCR and qPCR are indispensable tools for genomic research, functional genomics, and molecular biology studies. These techniques are crucial for validating findings from next-generation sequencing, studying gene-editing outcomes, and probing the dynamics of viral infections and microbial quantification.

End-User: Significant applications of dPCR & qPCR in the personalized drug development he

Digital PCR and real-time PCR methods are pivotal in academic research for their high precision and accuracy in quantitative gene expression analysis, validation of sequencing results, and single-cell analysis. The granularity of data provided by dPCR is especially valuable for detecting rare alleles and understanding variations at the single-molecule level in scientific studies, while qPCR's rapid real-time data capabilities allow for swift experimental iterations and educational applications. In the agriculture and life sciences sector, digital PCR and real-time PCR are indispensable tools for genetic trait analysis, genetically modified organism (GMO) detection, and pathogen identification. dPCR offers unparalleled sensitivity in quantifying DNA alterations that underpin trait selection in crop improvement programs, while qPCR is widely used for its versatility and rapid throughput in monitoring disease outbreaks in plants and livestock, ensuring agricultural productivity and biosecurity. CROs and CDMOs utilize digital and real-time PCR techniques to offer specialized services, such as biomarker discovery, clinical trial support, and quality control for drug development. Hospitals and diagnostic laboratories rely on the rapid and accurate diagnostics afforded by real-time PCR to detect infectious diseases, genetic disorders, and cancer biomarkers. In the clinical environment, the ease of integration and rapid turnaround time of qPCR are critical for patient management decisions. Digital PCR and real-time PCR are essential in pharmaceutical and biopharmaceutical research and development for drug target validation, pharmacogenomics, and quality control during manufacturing processes. The fine resolution of dPCR is particularly beneficial in the precise quantitation of low-abundance targets and in assessing minor variations in gene expression that may influence drug efficacy and safety. qPCR's adaptability streamlines the pharmaceutical pipeline by offering a robust method for high-throughput screening and validation in drug discovery and development.

Regional Insights

In the Americas, the digital PCR & real-time PCR market is showing robust growth, attributed to the region's strong biotechnology and pharmaceutical sectors, active government investments in healthcare research, and the wide adoption of technologically advanced diagnostic methods. The European market for digital PCR & real-time PCR is witnessing steady growth owing to the need for advanced capabilities to counter the increasing prevalence of infectious diseases, genetic disorders, and various types of cancer. Advanced healthcare infrastructure and significant investments in R&D activities in the biotechnology sector underpin the market expansion in the region. The growth in the Middle East and Africa is propelled by improving healthcare facilities, economic development, and increased access to innovative diagnostic technologies. The Asia-Pacific is emerging as the fastest-growing regional market for dPCR and qPCR technologies. The growth is largely fueled by the expanding biomedical industry in countries such as China, Japan, India, South Korea, and Australia. The region's large population base presents a significant demand for advanced diagnostic methods including dPCR and qPCR. Increased government expenditure on healthcare and the rising prevalence of chronic diseases are further catalyzing the market growth in the region.

FPNV Positioning Matrix

The FPNV Positioning Matrix is pivotal in evaluating the Digital PCR & Real-Time PCR Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).

Market Share Analysis

The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the Digital PCR & Real-Time PCR Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.

Key Company Profiles

The report delves into recent significant developments in the Digital PCR & Real-Time PCR Market, highlighting leading vendors and their innovative profiles. These include Abbott Laboratories, Inc., Agilent Technologies, Inc., Analytik Jena GmbH+Co. KG, Azure Biosystems Inc., Becton, Dickinson and Company, Bio-Rad Laboratories, Inc., Biocompare by CompareNetworks, Inc., BIOMERIEUX S.A., Bioneer Corporation, Danaher Corporation, ELITech Group, Enzo Life Sciences, Inc., Eppendorf SE, Etcon Analytical and Environmental Systems & Services Ltd., Explorea s.r.o, F. Hoffmann-La Roche AG, Global Engage Sdn. Bhd., Hangzhou Longgene Scientific Instruments Co., Ltd., Heal Force Bio-Meditech Holdings Limited, Integrated DNA Technologies, Inc., LABGENE Scientific SA, Merck KGaA, Meridian Bioscience, Inc., Promega Corporation, QIAGEN N.V., Quidel Corporation, R-Biopharm AG, RainSure Scientific, Roche Diagnostics Corporation, Solis BioDyne OU, STANDARD BIOTOOLS INC., Takara Bio USA, Inc., Thermo Fisher Scientific Inc., and Zymo Research Corp.

Market Segmentation & Coverage

This research report categorizes the Digital PCR & Real-Time PCR Market to forecast the revenues and analyze trends in each of the following sub-markets:

Type
- dPCR
- qPCR

Product Type
- Instruments
- Reagents & Consumables
- Services

Application
- Clinical Research
- Forensic Labs
- Research Institutes

End-User
- Academic & Research Institutes
- Agriculture & Lifescience
- CROs & CDMOs
- Hospitals & Diagnostic Laboratories
- Pharmaceutical & Biopharmaceutical Companies

Region
- Americas
  - Argentina
  - Brazil
  - Canada
  - Mexico
  - United States
    - California
    - Florida
    - Illinois
    - New York
    - Ohio
    - Pennsylvania
    - Texas
- Asia-Pacific
  - Australia
  - China
  - India
  - Indonesia
  - Japan
  - Malaysia
  - Philippines
  - Singapore
  - South Korea
  - Taiwan
  - Thailand
  - Vietnam

Europe, Middle East & Africa
- Denmark
- Egypt
- Finland
- France
- Germany
- Israel
- Italy
- Netherlands
- Nigeria
- Norway
- Poland
- Qatar
- Russia
- Saudi Arabia
- South Africa
- Spain
- Sweden
- Switzerland
- Turkey
- United Arab Emirates
- United Kingdom

The report offers valuable insights on the following aspects:

1. Market Penetration: It presents comprehensive information on the market provided by key players.

2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.

3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.

4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.

5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.

The report addresses key questions such as:

1. What is the market size and forecast of the Digital PCR & Real-Time PCR Market?

2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the Digital PCR & Real-Time PCR Market?

3. What are the technology trends and regulatory frameworks in the Digital PCR & Real-Time PCR Market?

4. What is the market share of the leading vendors in the Digital PCR & Real-Time PCR Market?

5. Which modes and strategic moves are suitable for entering the Digital PCR & Real-Time PCR Market?

Product Code: MRR-8760467AA4C1

1. Preface

1.1. Objectives of the Study
1.2. Market Segmentation & Coverage
1.3. Years Considered for the Study
1.4. Currency & Pricing
1.5. Language
1.6. Stakeholders

2. Research Methodology

2.1. Define: Research Objective
2.2. Determine: Research Design
2.3. Prepare: Research Instrument
2.4. Collect: Data Source
2.5. Analyze: Data Interpretation
2.6. Formulate: Data Verification
2.7. Publish: Research Report
2.8. Repeat: Report Update

3. Executive Summary

4. Market Overview

5. Market Insights

5.1. Market Dynamics
- 5.1.1. Drivers
  - 5.1.1.1. Benefits of dPCR & qPCR for clinical virology diagnostics
  - 5.1.1.2. Increasing incidences of genetic and infectious diseases
  - 5.1.1.3. Applications of dPCR & qPCR in authenticate plant-derived products
- 5.1.2. Restraints
  - 5.1.2.1. Stringent regulatory guidelines regarding dPCR & qPCR techniques
- 5.1.3. Opportunities
  - 5.1.3.1. Emergence of droplet digital PCR (ddPCR) technology
  - 5.1.3.2. Emerging applications of dPCR & qPCR in biomarker discovery
- 5.1.4. Challenges
  - 5.1.4.1. Limitations associated with dPCR & qPCR techniques
5.2. Market Segmentation Analysis
- 5.2.1. Type: Higher preferences for qPCR for high throughput and a broader dynamic range
- 5.2.2. Product Type: Growing demand for application-specific kits that address the needs of specialized end-users
- 5.2.3. Application: Higher potential in forensics for paternity testing and the detection of low-level DNA in crime scene investigations
- 5.2.4. End-User: Significant applications of dPCR & qPCR in the personalized drug development he
5.3. Market Disruption Analysis
5.4. Porter's Five Forces Analysis
- 5.4.1. Threat of New Entrants
- 5.4.2. Threat of Substitutes
- 5.4.3. Bargaining Power of Customers
- 5.4.4. Bargaining Power of Suppliers
- 5.4.5. Industry Rivalry
5.5. Value Chain & Critical Path Analysis
5.6. Pricing Analysis
5.7. Technology Analysis
5.8. Patent Analysis
5.9. Trade Analysis
5.10. Regulatory Framework Analysis

6. Digital PCR & Real-Time PCR Market, by Type

6.1. Introduction
6.2. dPCR
6.3. qPCR

7. Digital PCR & Real-Time PCR Market, by Product Type

7.1. Introduction
7.2. Instruments
7.3. Reagents & Consumables
7.4. Services

8. Digital PCR & Real-Time PCR Market, by Application

8.1. Introduction
8.2. Clinical Research
8.3. Forensic Labs
8.4. Research Institutes

9. Digital PCR & Real-Time PCR Market, by End-User

9.1. Introduction
9.2. Academic & Research Institutes
9.3. Agriculture & Lifescience
9.4. CROs & CDMOs
9.5. Hospitals & Diagnostic Laboratories
9.6. Pharmaceutical & Biopharmaceutical Companies

10. Americas Digital PCR & Real-Time PCR Market

10.1. Introduction
10.2. Argentina
10.3. Brazil
10.4. Canada
10.5. Mexico
10.6. United States

11. Asia-Pacific Digital PCR & Real-Time PCR Market

11.1. Introduction
11.2. Australia
11.3. China
11.4. India
11.5. Indonesia
11.6. Japan
11.7. Malaysia
11.8. Philippines
11.9. Singapore
11.10. South Korea
11.11. Taiwan
11.12. Thailand
11.13. Vietnam

12. Europe, Middle East & Africa Digital PCR & Real-Time PCR Market

12.1. Introduction
12.2. Denmark
12.3. Egypt
12.4. Finland
12.5. France
12.6. Germany
12.7. Israel
12.8. Italy
12.9. Netherlands
12.10. Nigeria
12.11. Norway
12.12. Poland
12.13. Qatar
12.14. Russia
12.15. Saudi Arabia
12.16. South Africa
12.17. Spain
12.18. Sweden
12.19. Switzerland
12.20. Turkey
12.21. United Arab Emirates
12.22. United Kingdom

13. Competitive Landscape

13.1. Market Share Analysis, 2023
13.2. FPNV Positioning Matrix, 2023
13.3. Competitive Scenario Analysis
- 13.3.1. Roche Launches Next-Generation qPCR System to Advance Clinical Needs in Molecular Diagnostics and Address Public Health Challenges
- 13.3.2. QIAGEN Launches New QIAcuity Digital PCR Kits and Updated Software to Expand Use by Biopharma and Food Safety Customers
- 13.3.3. Seegene and Werfen Partner on Syndromic qPCR Assays Development
13.4. Strategy Analysis & Recommendation

14. Competitive Portfolio

14.1. Key Company Profiles
14.2. Key Product Portfolio