Peptide Synthesis Market by Product, Technology, End User

Description

List of Tables

[186 Pages Report] The Peptide Synthesis Market size was estimated at USD 636.71 million in 2023 and expected to reach USD 683.44 million in 2024, at a CAGR 7.84% to reach USD 1,080.42 million by 2030.

Peptide synthesis is a complex and advanced chemical process that entails the formation of peptides, which are short chains of amino acids linked by peptide bonds. These peptides play several critical roles in various biological systems, including signaling, regulation of cellular processes, and maintaining structural components. The technique involves adding amino acids to a growing polypeptide chain stepwise while protecting specific functional groups and ensuring high fidelity throughout the process. There is a higher demand for peptide therapeutics due to their increased applications, and pharmaceutical research activities and funding are on the rise across various economies. Moreover, the cosmetics industry is experiencing a growing need for bioactive peptides, contributing to increased peptide synthesis adoption. The lack of standardized rules and regulations for peptide design and difficulties in peptide production hinders its usage. However, the introduction of advanced peptide synthesizers and technologies developed for peptide design and the potential utilization of peptides in nutraceuticals and food preservation is expected to boost their synthesis in the future.

KEY MARKET STATISTICS
Base Year [2023]	USD 636.71 million
Estimated Year [2024]	USD 683.44 million
Forecast Year [2030]	USD 1,080.42 million
CAGR (%)	7.84%

Product: Growing usage of reagents for forming peptide bonds during synthesis

Equipment used in peptide synthesis includes automated synthesizers that streamline the process by controlling temperature, mixing, filtration, and other parameters. Solid-phase peptide synthesizers are widely used in end-user sectors due to their ease of operation and rapid cycle times. Other essential equipment includes high-performance liquid chromatography (HPLC) systems for the purification and analysis of synthesized peptides, mass spectrometers for determining molecular weight, and lyophilizers for drying and long-term storage of peptides. Reagents constitute the building blocks required for forming peptide bonds during synthesis. Common reagents include amino acids (protected or unprotected), coupling agents, amino acids, and other products. Services encompass expertise provided by companies specializing in custom peptide synthesis to cater to specific research needs. These organizations offer end-to-end solutions covering peptide design consultation, synthesis optimization using various strategies such as solid-phase, solution-phase, or hybrid methods, post-synthesis processing including purification, characterization, and modification, and quality assurance through analytical techniques such as HPLC, mass spectrometry, and amino acid analysis. Outsourcing peptide synthesis services enables researchers to access resources and experience in developing complex peptides with high yields and purity.

Technology: Rising potential of hybris & recombinant technology as it offers high peptide yield and purity

Hybrid & recombinant technology brings together the benefits of organic synthesis and biotechnological processes, offering high peptide yield and purity. It provides the flexibility to manufacture complex and long-chain peptides, which can be quite challenging for chemical synthesis methods. By modifying gene sequences, researchers can synthesize specific peptides with desired properties. Solid-phase peptide synthesis (SPPS) is the most prevalent technology in peptide synthesis, offering industrial-scale production of short to middle-length peptides. Being an efficient and straightforward approach, it is preferred for synthesizing peptides with clear functional properties. Solution-phase synthesis is the traditional method of peptide synthesis involving the dissolving of amino acids in a solvent. Large-scale manufacturing of smaller peptides as it is time-consuming and less efficient for longer peptides. The process is incredibly useful for the synthesis of cyclic peptides, where the product requires a subsequent cyclization step.

End-User: Expanding usage of peptide synthesis by pharmaceutical & biopharmaceutical companies for drug discovery

In academic and research institutes, peptide synthesis is employed to generate custom peptides that serve as essential tools for understanding biological mechanisms and investigating molecular interactions. These synthesized peptides are widely used to develop novel therapeutic agents, drug screening assays, and diagnostic applications involving biomarkers. Contract development & manufacturing organizations (CDMOs) and contract research organizations (CROs) provide specialized services related to the design, synthesis, purification, and characterization of peptides for clients in the pharmaceutical and biotechnology sectors. By leveraging advanced synthetic methodologies such as solid-phase peptide synthesis and solution-phase peptide synthesis techniques, these organizations can deliver high-quality custom peptides suited to their client's specific requirements. For pharmaceutical and biotechnology companies, peptide synthesis is integral to drug discovery pipelines as it drives advancements in therapeutic areas, including oncology, immunotherapy, metabolic disorders, infectious diseases, inflammation, pain management, and cardiovascular medicine, among others. Utilizing sophisticated computational methods such as structure-based drug design alongside well-established experimental practices enables these companies to develop more potent and selective bioactive molecules by minimizing unwanted side effects or toxicities.

Regional Insights

Peptide synthesis is a crucial technique in the field of biochemistry and pharmaceutical research across the Americas. In North America, the United States holds a dominant position in peptide synthesis usage due to its well-established biopharmaceutical industry, extensive research infrastructure, and considerable investment in life sciences. In South America, countries such as Brazil and Mexico are witnessing increased adoption of peptide synthesis technologies due to expanding biotechnology sectors and governmental support towards research initiatives. The Asia-Pacific peptide synthesis market's robust growth can be attributed to increased R&D investments by governments and private entities, surging demand for novel therapeutic solutions, expanding pharmaceutical & biotechnology industries' footprint within the region, and a thriving CRO landscape. The peptide synthesis market in the EMEA region is experiencing significant growth, driven by technological advancements in synthesizers, increased funding for research and development activities, and a growing demand for synthetic peptides in pharmaceuticals, biotechnology, and other industries. The market has witnessed an influx of new players and collaborations among existing participants to develop innovative technologies for peptide synthesis.

FPNV Positioning Matrix

The FPNV Positioning Matrix is pivotal in evaluating the Peptide Synthesis Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).

Market Share Analysis

The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the Peptide Synthesis Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.

Key Company Profiles

The report delves into recent significant developments in the Peptide Synthesis Market, highlighting leading vendors and their innovative profiles. These include 2B Scientific Limited, AAPPTec, ABclonal, Inc., Advanced ChemTech, Almac Group Limited, AmbioPharm Inc., AnaSpec Inc., Bachem AG, Biocon Limited, Biosynth Ltd., Biotage, CEM Corporation, CPC Scientific Inc., Creative Diagnostics, Creative Peptides, CSBio, Enamine Ltd., GenScript Biotech Corporation, Gyros Protein Technologies AB, Hybio Pharmaceutical Co., Ltd., JPT Peptide Technologies GmbH by TheraCode GmbH, Kaneka Corporation, LifeTein LLC, Merck KGaA, New England BioGroup, LLC, Novo Nordisk A/S, PolyPeptide Group AG, Thermo Fisher Scientific Inc., and USV Private Limited.

Market Segmentation & Coverage

This research report categorizes the Peptide Synthesis Market to forecast the revenues and analyze trends in each of the following sub-markets:

Product
- Equipment
  - Chromatography Equipment
  - Lyophilizers
  - Peptide Synthesizers

Reagents
- Amino Acids
- Base Resins
- Peptide Coupling Reagents
- Peptide Labeling Reagents

Services

Technology
- Hybrid & Recombinant Technology
- Solid-Phase Peptide Synthesis
- Solution-Phase Synthesis

End User
- Academic & Research Institutes
- Contract Development & Manufacturing Organization/Contract Research Organization
- Pharmaceutical & Biotechnology Companies

Region
- Americas
  - Argentina
  - Brazil
  - Canada
  - Mexico
  - United States
    - California
    - Florida
    - Illinois
    - New York
    - Ohio
    - Pennsylvania
    - Texas
- Asia-Pacific
  - Australia
  - China
  - India
  - Indonesia
  - Japan
  - Malaysia
  - Philippines
  - Singapore
  - South Korea
  - Taiwan
  - Thailand
  - Vietnam

Europe, Middle East & Africa
- Denmark
- Egypt
- Finland
- France
- Germany
- Israel
- Italy
- Netherlands
- Nigeria
- Norway
- Poland
- Qatar
- Russia
- Saudi Arabia
- South Africa
- Spain
- Sweden
- Switzerland
- Turkey
- United Arab Emirates
- United Kingdom

The report offers valuable insights on the following aspects:

1. Market Penetration: It presents comprehensive information on the market provided by key players.

2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.

3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.

4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.

5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.

The report addresses key questions such as:

1. What is the market size and forecast of the Peptide Synthesis Market?

2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the Peptide Synthesis Market?

3. What are the technology trends and regulatory frameworks in the Peptide Synthesis Market?

4. What is the market share of the leading vendors in the Peptide Synthesis Market?

5. Which modes and strategic moves are suitable for entering the Peptide Synthesis Market?

Product Code: MRR-431388EE3B9B

1. Preface

1.1. Objectives of the Study
1.2. Market Segmentation & Coverage
1.3. Years Considered for the Study
1.4. Currency & Pricing
1.5. Language
1.6. Stakeholders

2. Research Methodology

2.1. Define: Research Objective
2.2. Determine: Research Design
2.3. Prepare: Research Instrument
2.4. Collect: Data Source
2.5. Analyze: Data Interpretation
2.6. Formulate: Data Verification
2.7. Publish: Research Report
2.8. Repeat: Report Update

3. Executive Summary

4. Market Overview

5. Market Insights

5.1. Market Dynamics
- 5.1.1. Drivers
  - 5.1.1.1. Higher need and applications of peptide therapeutics
  - 5.1.1.2. Increase in pharmaceutical research activities and funding across economies
  - 5.1.1.3. Growing demand for bioactive peptides from the cosmetics industry
- 5.1.2. Restraints
  - 5.1.2.1. Lack of standard peptide design rules and regulations
- 5.1.3. Opportunities
  - 5.1.3.1. Development of advanced peptide synthesizers and technologies for peptide design
  - 5.1.3.2. Emerging applications of peptides in nutraceuticals and food preservation
- 5.1.4. Challenges
  - 5.1.4.1. Difficulty in development of peptides and instability of the peptides
5.2. Market Segmentation Analysis
- 5.2.1. Product: Growing usage of reagents for forming peptide bonds during synthesis
- 5.2.2. Technology: Rising potential of hybris & recombinant technology as it offers high peptide yield and purity
- 5.2.3. End-User: Expanding usage of peptide synthesis by pharmaceutical & biopharmaceutical companies for drug discovery
5.3. Market Disruption Analysis
5.4. Porter's Five Forces Analysis
- 5.4.1. Threat of New Entrants
- 5.4.2. Threat of Substitutes
- 5.4.3. Bargaining Power of Customers
- 5.4.4. Bargaining Power of Suppliers
- 5.4.5. Industry Rivalry
5.5. Value Chain & Critical Path Analysis
5.6. Pricing Analysis
5.7. Technology Analysis
5.8. Patent Analysis
5.9. Trade Analysis
5.10. Regulatory Framework Analysis

6. Peptide Synthesis Market, by Product

6.1. Introduction
6.2. Equipment
6.3. Reagents
6.4. Services

7. Peptide Synthesis Market, by Technology

7.1. Introduction
7.2. Hybrid & Recombinant Technology
7.3. Solid-Phase Peptide Synthesis
7.4. Solution-Phase Synthesis

8. Peptide Synthesis Market, by End User

8.1. Introduction
8.2. Academic & Research Institutes
8.3. Contract Development & Manufacturing Organization/Contract Research Organization
8.4. Pharmaceutical & Biotechnology Companies

9. Americas Peptide Synthesis Market

9.1. Introduction
9.2. Argentina
9.3. Brazil
9.4. Canada
9.5. Mexico
9.6. United States

10. Asia-Pacific Peptide Synthesis Market

10.1. Introduction
10.2. Australia
10.3. China
10.4. India
10.5. Indonesia
10.6. Japan
10.7. Malaysia
10.8. Philippines
10.9. Singapore
10.10. South Korea
10.11. Taiwan
10.12. Thailand
10.13. Vietnam

11. Europe, Middle East & Africa Peptide Synthesis Market

11.1. Introduction
11.2. Denmark
11.3. Egypt
11.4. Finland
11.5. France
11.6. Germany
11.7. Israel
11.8. Italy
11.9. Netherlands
11.10. Nigeria
11.11. Norway
11.12. Poland
11.13. Qatar
11.14. Russia
11.15. Saudi Arabia
11.16. South Africa
11.17. Spain
11.18. Sweden
11.19. Switzerland
11.20. Turkey
11.21. United Arab Emirates
11.22. United Kingdom

12. Competitive Landscape

12.1. Market Share Analysis, 2023
12.2. FPNV Positioning Matrix, 2023
12.3. Competitive Scenario Analysis
- 12.3.1. Biosynth Extends Peptide Synthesis Offering With Pepceuticals Acquisition
- 12.3.2. GenScript Expands Peptide Production Capabilities to Include Neoantigen Peptides and APIs
- 12.3.3. Mesa Labs Acquires Belyntic's Peptide Purification Business
12.4. Strategy Analysis & Recommendation

13. Competitive Portfolio

13.1. Key Company Profiles
13.2. Key Product Portfolio