PUBLISHER: Knowledge Sourcing Intelligence | PRODUCT CODE: 1425117
PUBLISHER: Knowledge Sourcing Intelligence | PRODUCT CODE: 1425117
The atopic dermatitis drugs market is estimated to grow at a CAGR of 8.92% during the forecast period.
One of the most prevalent inflammatory skin disorders is atopic dermatitis (AD). Although it might manifest differently in each person, eczematous and itchy skin lesions are the hallmarks of AD. Asthma, food allergies, and ocular conditions including conjunctivitis are just a few of the comorbidities associated with AD. Topical corticosteroids, calcineurin inhibitors, and injectable biologic drugs are frequently used to treat AD.
Growing prevalence of offspring atopic dermatitis
Patients with the atopic triad experience symptoms as a result of compromised skin, upper respiratory, and lower respiratory tract barrier. There is a greater than 50% likelihood that if one parent has atopic dermatitis, so will their child. Up to 80% of the kids will be impacted if both parents are sick. Genetic changes include loss-of-function mutations in the epidermal protein filaggrin (Filament aggregation protein), which is converted to a natural moisturizing factor. Up to 30% of those with atopic dermatitis have filaggrin mutations, which can also put them at risk for allergic rhinitis, ichthyosis vulgaris, and keratosis pilaris.
Rising incidences of atopic dermatitis
According to the National Library of Medicine, in wealthy nations, 2% to 10% of adults and 10% to 30% of children are affected by atopic dermatitis which highly impacts the atopic dermatitis drugs industry. In recent decades, its incidence has climbed by two to three times. Greater latitudes have a greater prevalence of atopic dermatitis, which may be due to less sun exposure and less humidity. Based on the age of onset, atopic dermatitis is categorized into three subgroups, the most prevalent kind of atopic dermatitis, with around 60% of cases beginning before age 1, is early-onset atopic dermatitis (birth to two years old). 60% of cases are settled by the age of 12. Atopic dermatitis with a late start occurs when symptoms appear after puberty. Senile onset atopic dermatitis is an uncommon subtype that develops in adults beyond the age of 60.
Growth in the usage of medication applied to the skin
Various medications come in a range of strengths and can be applied as creams, gels, or ointments boosting the atopic dermatitis drugs industry. Calcineurin inhibitor-containing lotions or ointments may be an option for patients older than two. Examples include tacrolimus (Protopic) and pimecrolimus (Elidel). The patient must keep out of the direct sun while using these drugs. Additionally, the Food and Drug Administration is obligated to put a black box warning on certain products addressing the potential for lymphoma. This warning has been given because of a small number of cases of lymphoma among users of topical calcineurin inhibitors.
Introduction of new treatments
The severity of the illness, both currently and in the past, as well as comorbidities, have a significant role in AD care. The development of the eczema illness is significantly influenced by the epidermal barrier. Patient education, emollient treatment, and trigger avoidance are all part of the initial care. Emollients can be just as beneficial as topical corticosteroids (TCS) of low potency and have been shown to decrease the incidence of AD. In December 2022, the innovative, patient-tailored monoclonal antibody therapy rocatinlimab demonstrated excellent outcomes in patients with moderate to severe atopic dermatitis throughout the study and for up to 20 weeks after the treatment was terminated. This development is boosting the growth of the atopic dermatitis drug market.
In North America, it is projected that the atopic dermatitis drugs market will grow steadily.
The atopic dermatitis drug market in North America is anticipated to be fueled by the growing prevalence of atopic dermatitis and research initiatives in the region. For instance, a brand-new national skin research network called SkIN Canada (Skin Investigation Network of Canada) was introduced. Research priorities that are significant to patients, carers, and healthcare professionals are being established to influence the research landscape and guarantee its usefulness to patient care. By providing a coordinated multidisciplinary approach to patient management of AD, the integrated care pathways for atopic dermatitis (AD-ICPs) seek to close the gap between current AD treatment evidence-based guidelines and expert opinion based on everyday practice. Moreover, by combining interventions and elements from many guidelines, including quality assurance, and explaining care coordination, ICPs have the potential to improve guideline recommendations.
Atopic Dermatitis Clinical Trials
FDA Approvals for Atopic Dermatitis Drugs Drugs
Market Key Developments