Calcifediol Supplements Market - Forecasts from 2025 to 2030

The Calcifediol Supplements Market is expected to grow at a CAGR of 9.21%, reaching a market size of US$2,189.3 million in 2030 from US$1,409.4 million in 2025.

Calcifediol is an active form of Vitamin D found in the bloodstream, also known as 25-hydroxyvitamin D3. It is produced by the liver by hydroxylation of Vitamin D3 that we get from sunlight or diet. It is used to measure the Vitamin D level in the body.

Calcifediol supplements are a more advanced and powerful type of vitamin D supplement. It has been clinically demonstrated to increase vitamin D levels three times quicker and more efficiently than other methods. Calcifediol monohydrate (25-Hydroxyvitamin D3) is a vitamin D3 analogue created by hydroxylation of vitamin D3 (cholecalciferol) using the enzyme cholecalciferol 25-hydroxylase.

The increasing Vitamin D deficiency worldwide and the aging population are driving the market growth for its supplements. Calcifediol is a better alternative than other forms of Vitamin D supplements as it is absorbed more quickly and increases Vitamin D levels by 3 times in the body, thus leading to an increase in its demand. Moreover, its usage in treating secondary hyperparathyroidism, managing hypocalcemia, and preventing osteoporosis would help in increasing the calcifediol supplements market growth.

Calcifediol supplement market drivers

• Rising Vitamin D deficiency would drive the market growth for calcifediol supplements

Globally, there is an increase in the number of people with Vitamin D deficiency. At the same time, the number of geriatric populations is on the rise worldwide. These factors are creating demand for Vitamin D supplements. Calcifediol is a superior alternative to other vitamin D supplements. It offers an effective solution for addressing vitamin D deficiency, providing a faster and more efficient method to raise vitamin D levels than traditional vitamin D3 supplements.

As per a study done by the National Center of Biotechnology Information, there are 76.6% of participants had serum 25-hydroxyvitamin D deficiency below 75 nmol/l, showing a higher prevalence of deficiency of vitamin D. Globally, approximately 30-45% of people have vitamin D deficiency, making it around 1 billion people.

Calcifediol supplement market geographical outlook

• North America would be the largest market shareholder for calcifediol supplements in the forecast period

Region-wise, the global market is segmented into Asia-Pacific, North America, South America, Europe, Middle East and Africa. North America would hold the largest market share for Calcifediol supplements in the forecast period.

North America is experiencing a demographic shift towards the older population. In the United States of America, there are around 77 million people aged above 65, according to the U.S. Census Bureau Project. In Canada, the aging population is increasing, too. Vitamin D deficiency in the aging population, coupled with deficiency in a great number of adults, would significantly increase the demand for calcifediol supplements in the North American region. Though all the regions are facing the issue of vitamin D deficiency, North America, particularly the United States of America, would have the highest growth in the calcifediol supplement market as there are increasing trends among people for dietary supplements and the prevalence of advanced healthcare infrastructure coupled with significant innovations and the advancement in the health sector.

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Report Coverage:

• Historical data & forecasts from 2022 to 2030
• Growth Opportunities, Challenges, Supply Chain Outlook, Regulatory Framework, Customer Behaviour, and Trend Analysis
• Competitive Positioning, Strategies, and Market Share Analysis
• Revenue Growth and Forecast Assessment of segments and regions including countries
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The calcifediol supplement market is segmented and analyzed as given below:

By Type

• Immediate-release calcifediol
• Extended-release calcifediol

By Application

• Vitamin D Deficiency
• Osteoporosis
• Secondary hyperparathyroidism
• Others

By Geography

• North America
• United States
• Canada
• Mexico
• South America
• Brazil
• Argentina
• Others
• Europe
• UK
• Germany
• France
• Italy
• Others
• Middle East and Africa
• Saudi Arabia
• Israel
• Others
• Asia Pacific
• Japan
• China
• India
• South Korea
• Indonesia
• Thailand
• Others