PUBLISHER: Visiongain | PRODUCT CODE: 1809419
PUBLISHER: Visiongain | PRODUCT CODE: 1809419
The global Geographic Atrophy market is projected to grow at a CAGR of 13.1% by 2035.
The Geographic Atrophy Market Report 2025-2035 (Including Impact of U.S. Trade Tariffs): This report will prove invaluable to leading firms striving for new revenue pockets if they wish to better understand the industry and its underlying dynamics. It will be useful for companies that would like to expand into different industries or to expand their existing operations in a new region.
Growing Prevalence of Geographic Atrophy
Geographic atrophy (GA) is closely linked with ageing, predominantly affecting people aged 60 and above. As a result, population ageing stands out as one of the strongest drivers of future demand. A 2024 Journal of the American Medical Association (JAMA) study projects that global cases of age-related macular degeneration will rise from 196 million today to 288 million by 2040.
As prevalence rises, the need for effective therapies is intensifying. Biopharmaceutical companies are responding by advancing treatments designed with greater durability, improved safety, and enhanced usability for elderly patients. Uptake of recently approved drugs such as pegcetacoplan and avacincaptad pegol has already been strong across high-income regions, where ageing populations are expanding fastest. Beyond clinical impact, the demographic shift also represents a commercial imperative: drug makers must adapt by designing accessible therapies and building patient support programmes to serve a growing, vulnerable population segment.
Limited Efficacy of Current Therapies is Hindering the Market Growth
The therapeutic impact of currently approved complement inhibitors for geographic atrophy (GA) remains the subject of ongoing debate. While these drugs have demonstrated the ability to slow lesion growth, the effect is modest and does not consistently translate into meaningful improvements in functional vision. Results from the pivotal OAKS and DERBY Phase 3 trials showed average reductions in GA lesion enlargement of around 16-22% over one to two years, with clearer separation from sham groups emerging over time. However, improvements in key functional outcomes, such as best-corrected visual acuity, were not reliably achieved.
Safety concerns further complicate adoption. Post-marketing surveillance and registry data have reported clusters of intraocular inflammation and other retinal inflammatory events in treated patients, prompting tighter monitoring requirements and more selective patient eligibility. Coupled with the ongoing burden of frequent intravitreal injections, these factors have dampened enthusiasm for broad use.
In practice, current therapies provide meaningful yet limited benefits, with uptake largely confined to carefully chosen patient populations. For the wider retinal community, stronger long-term data on safety and functional outcomes remain essential before these treatments can achieve mainstream adoption.
What would be the Impact of US Trade Tariffs on the Global Geographic Atrophy Market ?
U.S. trade tariffs have the potential to indirectly influence the global market for geographic atrophy (GA) therapies by raising production costs for treatments and their delivery devices. While finished biopharmaceuticals such as GA drugs are often exempt from high tariffs due to their medical necessity, the upstream components essential to their manufacture-such as sterile fill-finish equipment, specialised glass vials, and injection devices-are frequently sourced from tariff-affected countries. Any increase in costs for these inputs drives up overall production expenses, which can, in turn, translate into higher treatment prices. Given that GA therapies already carry premium price points, even marginal cost increases risk complicating payer negotiations, restricting patient access, and slowing adoption in cost-sensitive healthcare systems.
The implications extend well beyond the U.S. Pharmaceutical companies typically operate integrated supply chains spanning multiple regions, and while large multinationals with diversified sourcing can absorb or offset tariff risks, smaller biotech firms dependent on single-source suppliers may face significant margin pressures. For these companies, partnerships with larger players may become a necessity. Over time, persistent tariffs could prompt more investment in localised manufacturing and supplier diversification, reshaping competitive dynamics and altering how quickly GA therapies can scale globally.
In response, companies may fast-track investments in domestic production sites or shift parts of their supply chains to tariff-neutral regions to mitigate exposure. This restructuring could elevate the role of emerging markets such as Asia Pacific and Latin America as alternative manufacturing hubs. However, such transitions demand considerable capital and time, potentially slowing innovation or delaying the availability of new therapies in the short term. In the longer run, the interaction between tariffs, localisation, and global demand is likely to redefine how GA treatments are priced, distributed, and adopted worldwide.
What Questions Should You Ask before Buying a Market Research Report?
You need to discover how this will impact the geographic atrophy market today, and over the next 10 years:
Segments Covered in the Report
In addition to the revenue predictions for the overall world market and segments, you will also find revenue forecasts for five regional and 19 leading national markets:
The report also includes profiles and for some of the leading companies in the Geographic Atrophy Market, 2025 to 2035, with a focus on this segment of these companies' operations.
Overall world revenue for Geographic Atrophy Market, 2025 to 2035 in terms of value the market will surpass US$7,400.0 million in 2025, our work calculates. We predict strong revenue growth through to 2035. Our work identifies which organizations hold the greatest potential. Discover their capabilities, progress, and commercial prospects, helping you stay ahead.