Picture
SEARCH
What are you looking for?
Need help finding what you are looking for? Contact Us
Compare

PUBLISHER: KuicK Research | PRODUCT CODE: 2021040

Cover Image

PUBLISHER: KuicK Research | PRODUCT CODE: 2021040

Global Targeted Alpha Therapy Market Size, Regulatory Approvals, Proprietary Technologies, Therapeutic Applications & Clinical Trials Insight 2030

PUBLISHED:
PAGES: 120 Pages
DELIVERY TIME: 1-2 business days
SELECT AN OPTION
PDF (Single User License)
USD 3300
PDF (Multi-User License)
USD 5100

Add to Cart

Global Targeted Alpha Therapy Market Size, Regulatory Approvals, Proprietary Technologies, Therapeutic Applications & Clinical Trials Insight 2030 Report findings & Highlights:

  • Global Targeted Alpha Therapy Market Outlook By Region
  • Current Market Overview & Future Growth Avenues
  • Number Of Targeted Alpha Therapy In Clinical Trials: > 30 Drugs
  • Targeted Alpha Therapy Clinical Trials Insight By Company, Indication & Phase
  • Dosage & Pricing insight On Approved Targeted Alpha Therapy
  • Targeted Alpha Therapy Proprietary Technology Platform Insights By Company
  • Targeted Alpha Therapy Applications By Cancer
  • Competitive Landscape

Need For Targeted Alpha Therapies & Why This Report?

Targeted Alpha Therapies represent an innovative technique in cancer treatment that utilizes the high linear energy transfer characteristic of alpha emitting isotopes to specifically target cancerous cells without damaging normal tissue. In contrast to other treatment modalities, Targeted Alpha Therapies provide specificity, efficacy, and the potential to circumvent resistance pathways, thus making them ideal for the treatment of metastatic and drug-resistant cancers. The shortcomings of other radiation emitters and traditional treatments have rendered the development of targeted therapies critical, placing Targeted Alpha Therapies in the spotlight for future cancer therapy techniques.

The global market or targeted alpha therapies is currently experiencing rapid growth due to the advancement of several alpha emitters, such as Actinium-225, Astatine-211, and Lead-212, through various clinical stages in 2026. In addition to this, there are already several therapeutic solutions that showed strong anti-tumor activity in the initial stages of development and can help in dealing with problems related to prostate cancer and hepatocellular carcinoma.

Clinical Trials Insight Included In Report

Clinical development continues to be an important factor behind the expansion of the Targeted Alpha Therapies market. In this report, we discuss various trials at different phases, from Phase I to Phase III, focusing on demographics, dosing regimens, drug combinations, and results. As an example, ALPHAMEDIX02 conducted a Phase II trial for the treatment of gastroenteropancreatic neuroendocrine tumors with 212Pb-DOTAMTATE, which yielded response rates as high as 60% even for patients that had been administered beta-emitting agents previously. Initial trials with Astatine-211 have also proved effective in treating recurrent thyroid malignancies.

Combination therapies are also covered in this report where Targeted Alpha Therapies have been combined with androgen receptor antagonists, chemotherapeutic agents, or immunotherapy to boost antitumor efficacy. With the help of the information provided in this report, it is possible to make an evaluation regarding both scientific and business viability.

Major Companies Driving Targeted Alpha Therapy R&D

The development landscape of targeted alpha therapies comprises of both mature players in the pharmaceutical industry and emerging players. Examples include companies like Actinium Pharmaceuticals, Orano Med, NAYA Therapeutics, and Fusion Pharma that are developing cutting-edge treatments, whereas strategic partnerships, like NAYA's alliance with Alpha Nuclide in China to produce Astatine-211, emphasize the significance of international logistics and scalable manufacturing processes.

There are also merger and acquisition activities that continue to shape the competition environment as seen by the recent acquisition of Fusion Pharmaceuticals by AstraZeneca and the acquisition of RayzeBio by Bristol Myers Squibb. Such mergers and acquisitions represent strategies geared towards gaining access to TAT technology, expanding the pipeline, and ensuring consistent access to isotopes.

Technology Platforms & Strategic Insights Offered

This report offers an insightful analysis of the technologies used in Targeted Alpha Therapies manufacturing, including the platform and processes involved, and the latest innovations in this domain. The study identifies some critical enabling factors such as the process of generating Actinium-225 from a cyclotron and the extraction of Lead-212 through chemistry. The report also captures the trends within the Targeted Alpha Therapy theranostics, real-time imaging, and oncology domains.

Future Outlook For Targeted Alpha Therapy

There is a lot of potential in the targeted alpha therapy industry, and that has been fueled by several successes in the area. As a result of advancements in technology and the broadening scope of Targeted Alpha Therapy applications outside of oncology, it is set to be one of the pillars of precision medicine in the future. By utilizing this report, stakeholders can obtain valuable insights about new opportunities, competitive position, and technology differentiators that are essential for making an informed decision in the ever-changing therapeutic field.

Table of Contents

1. Research Methodology

2. Introduction To Targeted Alpha Therapy

  • 2.1 Overview
  • 2.2 Alpha Radiation vs. Beta & Gamma Radiation In Cancer Therapy

3. Targeted Alpha Therapy - Structure & Mechanism Of Action

  • 3.1 Structure
  • 3.2 Mechanism Of Action

4. Targeted Alpha Therapy Applications By Cancer

  • 4.1 Hematological Malignancies
  • 4.2 Solid Tumors

5. Global Targeted Alpha Therapy Market Insight

  • 5.1 Current Market Scenario
  • 5.2 Future Growth Avenues

6. Targeted Alpha Therapy Market Insight By Region

  • 6.1 US
  • 6.2 Europe
  • 6.3 China
  • 6.4 Japan
  • 6.5 Australia

7. Global Targeted Alpha Therapy Clinical Trials Overview

  • 7.1 By Phase
  • 7.2 By Company
  • 7.3 By Indication

8. Targeted Alpha Therapy Clinical Trials Insight By Company, Indication & Phase

  • 8.1 Preclinical
  • 8.2 Phase I
  • 8.3 Phase I/II
  • 8.4 Phase II
  • 8.5 Phase II/III
  • 8.6 Phase III

9. Marketed Targeted Alpha Therapy Clinical Insight By Company, Country & Indication

10. Xofigo - 1st Approved Targeted Alpha Therapy

  • 10.1 Overview & Patent Insight
  • 10.2 Pricing & Dosing

11. Targeted Alpha Therapy - Proprietary Technology Platform By Company

12. Global Targeted Alpha Therapy Market Dynamics

  • 12.1 Drivers & Opportunities
  • 12.2 Challenges & Restraints

13. Competitive Landscape

  • 13.1 Actinium Pharma
  • 13.2 AdvanCell
  • 13.3 Ariceum Therapeutics
  • 13.4 Bayer
  • 13.5 Fusion Pharma
  • 13.6 Orano Med
  • 13.7 Perspective Therapeutics
  • 13.8 RadioMedix
  • 13.9 RayzeBio
  • 13.10 Telix Pharmaceuticals

List of Figures

  • Figure 3-1: Targeted Alpha Therapy - Structure
  • Figure 3-2: Targeted Alpha Therapy - Mechanism Of Action
  • Figure 4-1: LIN-AC225-AML02 Phase 1/2 (NCT03867682) Study - Initiation & Completion Year
  • Figure 4-2: RG1121028 Phase 1 (NCT04579523) Study - Initiation & Completion Year
  • Figure 4-3: 225Ac-DOTA-daratumumab Phase 1 (NCT05363111) Study - Initiation & Completion Year
  • Figure 4-4: PAnTHA Phase 1 (NCT06217822) Study - Initiation & Completion Year
  • Figure 4-5: 2022-502623-22-00 Phase 1 (NCT06052306) Study - Initiation & Completion Year
  • Figure 4-6: TheraPb Phase I/II (NCT05720130) Study - Initiation & Completion Year
  • Figure 4-7: VMT-a-NET-T101 Phase I/II (NCT05636618) Study - Initiation & Completion Year
  • Figure 4-8: ALPHAMEDIX02 Phase II (NCT05153772) Study - Initiation & Completion Year
  • Figure 5-1: Factors Influencing Future Market of Targeted Alpha Therapies
  • Figure 5-2: Global - Targeted Alpha Therapy Market Opportunity (US$ Million), 2026 & 2030
  • Figure 7-1: Global - - Number Of Targeted Alpha Therapy Clinical Pipeline By Phase, 2026
  • Figure 7-2: Global - - Number Of Targeted Alpha Therapy Clinical Pipeline By Company, 2026
  • Figure 7-3: Global - - Number Of Targeted Alpha Therapy Clinical Pipeline By Indication, 2026
  • Figure 11-1: Fusion Pharma - Fast-Clear(TM) Linker Technology
  • Figure 11-2: AdvanCell - Proprietary 212Pb Production Technology
  • Figure 11-3: Cellectar Biosciences - Phospholipid Ether (PLE) Platform Technology
  • Figure 11-4: Perspective Therapeutics - Proprietary Technology & Pb-212 Isotope Generator VMT-a-NET
  • Figure 12 1: Global Targeted Alpha Therapy Market - Drivers & Opportunities
  • Figure 12 2: Global Targeted Alpha Therapy Market - Challenges & Restraints

List of Tables

  • Table 2-1: Alpha Radiation vs. Beta & Gamma Radiation In Cancer Therapy
  • Table 8-1: Targeted Alpha Therapies In Preclinical Stage, 2026
  • Table 8-2: Targeted Alpha Therapies In Phase I, 2026
  • Table 8-3: Targeted Alpha Therapies In Phase I/II, 2026
  • Table 8-4: Targeted Alpha Therapies In Phase II, 2026
  • Table 8-5: Targeted Alpha Therapies In Phase II/III, 2026
  • Table 8-6: Targeted Alpha Therapies In Phase III, 2026
  • Table 9-1: Marketed Targeted Alpha Therapies, 2026
  • Table 10-1: Xofigo - Decay Correction Factor
Have a question?
Picture

Jeroen Van Heghe

Manager - EMEA

+32-2-535-7543

Picture

Christine Sirois

Manager - Americas

+1-860-674-8796

Questions? Please give us a call or visit the contact form.
Hi, how can we help?
Contact us!