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PUBLISHER: Mellalta Meets LLP | PRODUCT CODE: 1634495

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PUBLISHER: Mellalta Meets LLP | PRODUCT CODE: 1634495

Genitourinary tract cancer | Primary Research (KOL's Insight) | Market Intelligence | Epidemiology & Market Forecast-2035

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A broad category of tumors, genitourinary (GU) malignancies have a variety of cellular causes, biological traits, and therapeutic strategies. The most typical histological subtypes of carcinomas include those in the kidney, bladder, prostate, and testis. Metastatic GU malignancies have a wide range of prognoses and treatments, which highlights the wide range of biological diversity within this group. For instance, surgically removing the primary tumor and any metastatic foci may be curative in cases of renal cell cancer, but chemotherapy is typically effective in cases of testicular germ cell cancer, even when there are numerous metastases. Long-lasting disease remission can occasionally be brought on by immunotherapy with IL-2 in metastatic renal cell carcinoma, while hormone therapy can manage prostate cancer for many years without curing it. Importantly, not all GU cancers can be treated with these methods.

Description

A broad category of tumors, genitourinary (GU) malignancies have a variety of cellular causes, biological traits, and therapeutic strategies. The most typical histological subtypes of carcinomas include those in the kidney, bladder, prostate, and testis. Metastatic GU malignancies have a wide range of prognoses and treatments, which highlights the wide range of biological diversity within this group. For instance, surgically removing the primary tumor and any metastatic foci may be curative in cases of renal cell cancer, but chemotherapy is typically effective in cases of testicular germ cell cancer, even when there are numerous metastases. Long-lasting disease remission can occasionally be brought on by immunotherapy with IL-2 in metastatic renal cell carcinoma, while hormone therapy can manage prostate cancer for many years without curing it. Importantly, not all GU cancers can be treated with these methods.

Genitourinary tract cancer (Epidemiology)

Each year, approximately 275,000 people are diagnosed with bladder cancer worldwide, and 108,000 people pass away from the condition. 90% of bladder cancers diagnosed in developed nations are TCC. The majority of bladder cancers are squamous cell carcinomas in developing nations, particularly in the Middle East and Africa, and the majority of these cancers are secondary to schistosome infection. The most prevalent type of urinary tract cancer in China is thought to be urothelial carcinoma. In endemic schistosomiasis regions of Africa, particularly in Sudan and Egypt, where CSC accounts for two-thirds to three-quarters of all bladder malignancies, SCC is most prevalent. While the situation has remained unchanged in other regions of Africa, recent studies from Egypt have shown that this trend has reversed as a result of improved schistosomiasis control in the region. Egypt's transition to TCC, which has a stronger association with smoking, is thought to be influenced by rising smoking rates.

Genitourinary tract cancer -Current Market Size & Forecast Trends

The genitourinary tract cancer market is projected to experience steady growth, with the global genitourinary drugs market estimated at USD 29.39 billion in 2023 and expected to reach approximately USD 33.15 billion by 2034, reflecting a compound annual growth rate (CAGR) of 1.1% during this period. The market is driven by increasing prevalence of genitourinary cancers, including prostate, bladder, and cervical cancers, alongside advancements in treatment options such as targeted therapies and immunotherapies. Notably, the prostate cancer segment held a significant revenue share, accounting for about 28.3% of the market in 2022, while the bladder cancer market alone was valued at around USD 3.9 billion in 2023, projected to reach USD 5.4 billion by 2034 at a CAGR of 3.09%. North America is expected to dominate the market due to its advanced healthcare infrastructure and high prevalence of genitourinary diseases, while the Asia-Pacific region is anticipated to witness the fastest growth due to increasing awareness and healthcare access. Overall, the genitourinary tract cancer market is well-positioned for continued expansion through 2035 as new therapies and diagnostic technologies emerge.

Cancers of the reproductive tract and the urinary system can both be classified as genitourinary cancers. Cancers of the urinary system, including those of the bladder, kidney, and adrenal gland, as well as the reproductive tract, including those of the penile, prostate, and testicles, also come in same category. Testicular, penile, and adrenal cancers are the least frequent types of genitourinary cancers, while prostate, bladder, and kidney cancers are the most common. Genitourinary cancers may be treated with radiation, surgery, or chemotherapy alone or in combination, depending on the stage and specific circumstances. Numerous cancers, including genitourinary malignancies, are being treated with immunotherapy, and this field is developing quickly. Based on preclinical data and a growing body of clinical data, a particularly promising strategy is the combination of radiotherapy (RT) and immunotherapy to enhance the local efficacy of RT to eradicate tumors as well as to enable better and more durable systemic responses with immunotherapy agents.

Report Highlights

Genitourinary tract cancer - Current Market Trends

Genitourinary tract cancer - Current & Forecasted Cases across the G8 Countries

Genitourinary tract cancer - Market Opportunities and Sales Potential for Agents

Genitourinary tract cancer - Patient-based Market Forecast to 2035

Genitourinary tract cancer - Untapped Business Opportunities

Genitourinary tract cancer - Product Positioning Vis-a-vis Competitors' Products

Genitourinary tract cancer - KOLs Insight

Table of Content

1. Genitourinary tract cancer Background

  • 1.1. Genitourinary tract cancer Definition
  • 1.2. Signs and Symptoms
  • 1.3. Pathogenesis
  • 1.4. Clinical Manifestation
  • 1.5. Genitourinary tract cancer biomarkers
  • 1.6. Diagnosis

2. Epidemiology Estimated and Forecast to 2035

  • 2.1. Epidemiology Research Method & Data Sources Used
  • 2.2. United States
    • 2.2.1. Incident Cases of Genitourinary tract cancer
    • 2.2.2. Diagnosed and treatable cases of Genitourinary tract cancer by line of therapies (LOT)
  • 2.3. United Kingdom
    • 2.3.1. Incident Cases of Genitourinary tract cancer
    • 2.3.2. Diagnosed and treatable cases of Genitourinary tract cancer by line of therapies (LOT)
  • 2.4. Spain
    • 2.4.1. Incident Cases of Genitourinary tract cancer
    • 2.4.2. Diagnosed and treatable cases of Genitourinary tract cancer by line of therapies (LOT)
  • 2.5. Germany
    • 2.5.1. Incident Cases of Genitourinary tract cancer
    • 2.5.2. Diagnosed and treatable cases of Genitourinary tract cancer by line of therapies (LOT)
  • 2.6. France
    • 2.6.1. Incident Cases of Genitourinary tract cancer
    • 2.6.2. Diagnosed and treatable cases of Genitourinary tract cancer by line of therapies (LOT)
  • 2.7. Italy
    • 2.7.1. Incident Cases of Genitourinary tract cancer
    • 2.7.2. Diagnosed and treatable cases of Genitourinary tract cancer by line of therapies (LOT)
  • 2.8. Japan
    • 2.8.1. Incident Cases of Genitourinary tract cancer
    • 2.8.2. Diagnosed and treatable cases of Genitourinary tract cancer by line of therapies (LOT)
  • 2.9. China
    • 2.9.1. Incident Cases of Genitourinary tract cancer
    • 2.9.2. Diagnosed and treatable cases of Genitourinary tract cancer by line of therapies (LOT)
  • 2.10. Current Unmet Needs in Genitourinary tract cancer

3. Current Treatment Paradigm

  • 3.1. Treatment/Prevention guidelines
  • 3.2. Regulatory Approvals/Indication and Current Benchmarks

4. KOLs Insight (US, EU, JP, CH)

  • 4.1. Unmet Needs
  • 4.2. Analysis of the progress in terms of approvals & current pipeline
  • 4.3. Impact on the treatment algorithm and product positioning
  • 4.4. Relevance of new targets/platforms/ Therapy Uptake Share %
  • 4.5. Physicians Preferences for the new pharmacological agents

5. What's New in 2024/2025

6. Future Treatment Paradigm

  • 6.1. Genitourinary tract cancer Competitor Landscape and Approvals Anticipated
  • 6.2. Future Treatment Algorithms and Competitor Positioning
  • 6.3. Key Data Summary for Emerging Treatment

7. Late Phase Therapies Strategic Considerations in Genitourinary tract cancer

8. Total Market Forecast

  • 8.1. Key Summary Findings
    • 8.1.1. G8 total Market for Genitourinary tract cancer 2022-2035 (USD Million)
    • 8.1.2. G8 total Market for Genitourinary tract cancer by Therapies 2022-2035 (USD Million)

9. Market Forecast by Country

  • 9.1. United States
    • 9.1.1. United States Market for Genitourinary tract cancer 2022-2035 (USD Million)
    • 9.1.2. United States Market for Genitourinary tract cancer by Therapies 2022-2035 (USD Million)
  • 9.2. Germany
    • 9.2.1. Germany Market for Genitourinary tract cancer 2022-2035 (USD Million)
    • 9.2.2. Germany Market for Genitourinary tract cancer by Therapies 2022-2035 (USD Million)
  • 9.3. France
    • 9.3.1. France Market for Genitourinary tract cancer 2022-2035 (USD Million)
    • 9.3.2. France Market for Genitourinary tract cancer by Therapies 2022-2035 (USD Million)
  • 9.4. Italy
    • 9.4.1. Italy Market for Genitourinary tract cancer 2022-2035 (USD Million)
    • 9.4.2. Italy Market for Genitourinary tract cancer by Therapies 2022-2035 (USD Million)
  • 9.5. Spain
    • 9.5.1. Spain Market for Genitourinary tract cancer 2022-2035 (USD Million)
    • 9.5.2. Spain Market for Genitourinary tract cancer by Therapies 2022-2035 (USD Million)
  • 9.6. United Kingdom
    • 9.6.1. United Kingdom Market for Genitourinary tract cancer 2022-2035 (USD Million)
    • 9.6.2. United Kingdom Market for Genitourinary tract cancer by Therapies 2022-2035 (USD Million)
  • 9.7. Japan
    • 9.7.1. Japan Market for Genitourinary tract cancer 2022-2035 (USD Million)
    • 9.7.2. Japan Market for Genitourinary tract cancer by Therapies 2022-2035 (USD Million)
  • 9.8. China
    • 9.8.1. China Market for Genitourinary tract cancer 2022-2035 (USD Million)
    • 9.8.2. China Market for Genitourinary tract cancer by Therapies 2022-2035 (USD Million)

10. Market Drivers and Barriers

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Jeroen Van Heghe

Manager - EMEA

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Christine Sirois

Manager - Americas

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