PUBLISHER: Polaris Market Research | PRODUCT CODE: 1786877
PUBLISHER: Polaris Market Research | PRODUCT CODE: 1786877
U.S. Next-Generation Sequencing Library Preparation Market Size, Share, Trends, Industry Analysis Report By Sequencing Type (Targeted Genome Sequencing, Whole Genome Sequencing), By Product, By Application, By End Use - Market Forecast, 2025-2034
The U.S. next-generation sequencing library preparation market size is expected to reach USD 2,167.71 million by 2034, according to a new study by Polaris Market Research. The report "U.S. Next-Generation Sequencing Library Preparation Market Share, Size, Trends, Industry Analysis Report By Sequencing Type (Targeted Genome Sequencing, Whole Genome Sequencing), By Product, By Application, By End Use; Market Forecast, 2025-2034" gives a detailed insight into current market dynamics and provides analysis on future market growth.
Next-generation sequencing library preparation is a crucial step in the sequencing workflow, involving the conversion of DNA or RNA samples into a format compatible with high-throughput sequencing platforms. The process includes fragmenting the nucleic acids, attaching specialized adapter sequences, and amplifying the material to generate a sequencing-ready library. The quality of library preparation directly impacts the accuracy and efficiency of sequencing.
Next-generation sequencing library preparation is widely used across genomics research, clinical diagnostics, and biotechnology. In whole-genome sequencing (WGS), it enables comprehensive analysis of an organism's DNA, aiding in genetic variant detection and evolutionary studies.
U.S. Next-Generation Sequencing Library Preparation Market Report Highlights
In terms of sequencing type, the targeted genome sequencing segment accounted for 63.37% of revenue market share in 2024. Clinical researchers and diagnostic laboratories favored this approach due to its cost-effectiveness, high accuracy, and efficiency in identifying specific genetic variants associated with inherited diseases and cancers.
The whole genome sequencing segment, based on sequencing type, is projected to hold a substantial share in the coming years, owing to advancements in sequencing technologies and declining costs.
Based on product, the reagents & consumables segment dominated the market share in 2024 due to recurring demand for library preparation kits, enzymes, adapters, and amplification reagents used in every sequencing run.
In terms of application, the drug & biomarker discovery segment held the largest revenue share in 2024 due to the crucial role of next-generation sequencing library preparation in precision medicine and pharmaceutical research.
Based on end use, the academic and research institutions segment accounted for 37.83% of revenue market share in 2024 due to strong federal and private funding for genomics research and large-scale sequencing projects.
A few key players in the U.S. next-generation sequencing library preparation market include Agilent Technologies, Inc.; BD; F. Hoffmann-La Roche AG, Inc.; Illumina, Inc.; New England Biolabs Inc.; Oxford Nanopore Technologies; Pacific Biosciences of California, Inc.; QIAGEN N.V.; Revvity, Inc.; Thermo Fisher Scientific Inc.; and Twist Bioscience.
Polaris Market Research has segmented the U.S. next-generation sequencing library preparation market report on the basis of sequencing type, product, application, and end use:
By Sequencing Type Outlook (Revenue, USD Million, 2020-2034)
Targeted Genome Sequencing
Whole Genome Sequencing
Whole Exome Sequencing
Other
By Product Outlook (Revenue, USD Million, 2020-2034)
Reagents & Consumables
DNA Library Preparation Kits
RNA Library Preparation Kits
Other
Instruments
By Application Outlook (Revenue, USD Million, 2020-2034)
Drug & Biomarker Discovery
Disease Diagnostics
Cancer Diagnostics
Reproductive Health Diagnostics
Infectious Disease Diagnostics
Other
Others
By End Use Outlook (Revenue, USD Million, 2020-2034)
Hospitals and Clinics
Academic and Research Institutions
Pharmaceutical and Biotechnology Companies
Others
Table of Contents
1. Introduction
- 1.1. Report Description
- 1.1.1. Objectives of the Study
- 1.1.2. Market Scope
- 1.1.3. Assumptions
- 1.2. Stakeholders
2. Executive Summary
- 2.1. Market Highlights
3. Research Methodology
- 3.1. Overview
- 3.1.1. Data Mining
- 3.2. Data Source
- 3.2.1. Primary Source
- 3.2.2. Secondary Source
4. U.S. Next-Generation Sequencing Library Preparation Market Insights
- 4.1. U.S. Next-Generation Sequencing Library Preparation Market - Market Snapshot
- 4.2. U.S. Next-Generation Sequencing Library Preparation Market Dynamics
- 4.2.1. Drivers and Opportunities
- 4.2.1.1. Technological Innovations Enhancing Library Preparation Processes
- 4.2.1.2. Expansion of Applications in Personalized Medicine and Drug Discovery
- 4.2.2. Restraints and Challenges
- 4.2.2.1. High Costs of Library Preparation Kits
- 4.2.1. Drivers and Opportunities
- 4.3. Porter's Five Forces Analysis
- 4.3.1. Bargaining Power of Suppliers (Moderate)
- 4.3.2. Threats of New Entrants: (Low)
- 4.3.3. Bargaining Power of Buyers (Moderate)
- 4.3.4. Threat of Substitute (Moderate)
- 4.3.5. Rivalry among existing firms (High)
- 4.4. PESTEL Analysis
- 4.5. U.S. Next-Generation Sequencing Library Preparation Market Trends
- 4.6. Value Chain Analysis
5. U.S. Next-Generation Sequencing Library Preparation Market, by Sequencing Type
- 5.1. Key Findings
- 5.2. Introduction
- 5.2.1. U.S. Next-Generation Sequencing Library Preparation Market, by Sequencing Type, 2020-2034 (USD Million)
- 5.3. Targeted Genome Sequencing
- 5.3.1. U.S. Next-Generation Sequencing Library Preparation Market, by Targeted Genome Sequencing, by Region, 2020-2034 (USD Million)
- 5.4. Whole Genome Sequencing
- 5.4.1. U.S. Next-Generation Sequencing Library Preparation Market, by Whole Genome Sequencing, by Region, 2020-2034 (USD Million)
- 5.4.2. Whole Exome Sequencing
- 5.4.2.1. U.S. Next-Generation Sequencing Library Preparation Market, by Whole Exome Sequencing, by Region, 2020-2034 (USD Million)
- 5.4.3. Others
- 5.4.3.1. U.S. Next-Generation Sequencing Library Preparation Market, by Others, by Region, 2020-2034 (USD Million)
6. U.S. Next-Generation Sequencing Library Preparation Market, by Product
- 6.1. Key Findings
- 6.2. Introduction
- 6.2.1. U.S. Next-Generation Sequencing Library Preparation Market, by Product, 2020-2034 (USD Million)
- 6.3. Reagents & Consumables
- 6.3.1. U.S. Next-Generation Sequencing Library Preparation Market, by Reagents & Consumables, by Region, 2020-2034 (USD Million)
- 6.3.2. DNA Library Preparation Kits
- 6.3.2.1. U.S. Next-Generation Sequencing Library Preparation Market, by DNA Library Preparation Kits, by Region, 2020-2034 (USD Million)
- 6.3.3. RNA Library Preparation Kits
- 6.3.3.1. U.S. Next-Generation Sequencing Library Preparation Market, by RNA Library Preparation Kits, by Region, 2020-2034 (USD Million)
- 6.3.4. Others
- 6.3.4.1. U.S. Next-Generation Sequencing Library Preparation Market, by Others, by Region, 2020-2034 (USD Million)
- 6.4. Instruments
- 6.4.1. U.S. Next-Generation Sequencing Library Preparation Market, by Instruments, by Region, 2020-2034 (USD Million)
7. U.S. Next-Generation Sequencing Library Preparation Market, by Application
- 7.1. Key Findings
- 7.2. Introduction
- 7.2.1. U.S. Next-Generation Sequencing Library Preparation Market, by Application, 2020-2034 (USD Million)
- 7.3. Drug & Biomarker Discovery
- 7.3.1. U.S. Next-Generation Sequencing Library Preparation Market, by Drug & Biomarker Discovery, by Region, 2020-2034 (USD Million)
- 7.4. Disease Diagnostics
- 7.4.1. U.S. Next-Generation Sequencing Library Preparation Market, by Disease Diagnostics, by Region, 2020-2034 (USD Million)
- 7.4.2. Cancer Diagnostics
- 7.4.2.1. U.S. Next-Generation Sequencing Library Preparation Market, by Cancer Diagnostics, by Region, 2020-2034 (USD Million)
- 7.4.3. Reproductive Health Diagnostics
- 7.4.3.1. U.S. Next-Generation Sequencing Library Preparation Market, by Reproductive Health Diagnostics, by Region, 2020-2034 (USD Million)
- 7.4.4. Infectious Disease Diagnostics
- 7.4.4.1. U.S. Next-Generation Sequencing Library Preparation Market, by Infectious Disease Diagnostics, by Region, 2020-2034 (USD Million)
- 7.4.5. Others
- 7.4.5.1. U.S. Next-Generation Sequencing Library Preparation Market, by Others, by Region, 2020-2034 (USD Million)
- 7.5. Others
- 7.5.1. U.S. Next-Generation Sequencing Library Preparation Market, by Others, by Region, 2020-2034 (USD Million)
8. U.S. Next-Generation Sequencing Library Preparation Market, by End Use
- 8.1. Key Findings
- 8.2. Introduction
- 8.2.1. U.S. Next-Generation Sequencing Library Preparation Market, by End Use, 2020-2034 (USD Million)
- 8.3. Hospitals and Clinics
- 8.3.1. U.S. Next-Generation Sequencing Library Preparation Market, by Hospitals and Clinics, by Region, 2020-2034 (USD Million)
- 8.4. Academic & Research Institutes
- 8.4.1. U.S. Next-Generation Sequencing Library Preparation Market, by Academic & Research Institutes, by Region, 2020-2034 (USD Million)
- 8.5. Pharmaceutical and Biotechnology Companies
- 8.5.1. U.S. Next-Generation Sequencing Library Preparation Market, by Pharmaceutical and Biotechnology Companies, by Region, 2020-2034 (USD Million)
- 8.6. Others
- 8.6.1. U.S. Next-Generation Sequencing Library Preparation Market, by Others, by Region, 2020-2034 (USD Million)
9. Competitive Landscape
- 9.1. Expansion and Acquisition Analysis
- 9.1.1. Expansion
- 9.1.2. Acquisitions
- 9.2. Partnerships/Collaborations/Agreements/Exhibitions
10. Company Profiles
- 10.1. Agilent Technologies, Inc.
- 10.1.1. Company Overview
- 10.1.2. Financial Performance
- 10.1.3. Product Benchmarking
- 10.1.4. Recent Development
- 10.2. BD
- 10.2.1. Company Overview
- 10.2.2. Financial Performance
- 10.2.3. Product Benchmarking
- 10.2.4. Recent Development
- 10.3. F. Hoffmann-La Roche AG, Inc.
- 10.3.1. Company Overview
- 10.3.2. Financial Performance
- 10.3.3. Product Benchmarking
- 10.3.4. Recent Development
- 10.4. Illumina, Inc.
- 10.4.1. Company Overview
- 10.4.2. Financial Performance
- 10.4.3. Product Benchmarking
- 10.4.4. Recent Development
- 10.5. New England Biolabs Inc.
- 10.5.1. Company Overview
- 10.5.2. Financial Performance
- 10.5.3. Product Benchmarking
- 10.5.4. Recent Development
- 10.6. Oxford Nanopore Technologies
- 10.6.1. Company Overview
- 10.6.2. Financial Performance
- 10.6.3. Product Benchmarking
- 10.6.4. Recent Development
- 10.7. Pacific Biosciences of California, Inc.
- 10.7.1. Company Overview
- 10.7.2. Financial Performance
- 10.7.3. Product Benchmarking
- 10.7.4. Recent Development
- 10.8. QIAGEN N.V.
- 10.8.1. Company Overview
- 10.8.2. Financial Performance
- 10.8.3. Product Benchmarking
- 10.8.4. Recent Development
- 10.9. Revvity, Inc.
- 10.9.1. Company Overview
- 10.9.2. Financial Performance
- 10.9.3. Product Benchmarking
- 10.9.4. Recent Development
- 10.10. Twist Bioscience
- 10.10.1. Company Overview
- 10.10.2. Financial Performance
- 10.10.3. Product Benchmarking
- 10.10.4. Recent Development
- 10.11. Thermo Fisher Scientific Inc.
- 10.11.1. Company Overview
- 10.11.2. Financial Performance
- 10.11.3. Product Benchmarking
- 10.11.4. Recent Development
List of Tables:
- Table 1 U.S. Next-Generation Sequencing Library Preparation Market, by Sequencing Type, 2020-2034 (USD Million)
- Table 2 U.S. Next-Generation Sequencing Library Preparation Market, by Product, 2020-2034 (USD Million)
- Table 3 U.S. Next-Generation Sequencing Library Preparation Market, by Application, 2020-2034 (USD Million)
- Table 4 U.S. Next-Generation Sequencing Library Preparation Market, by End Use, 2020-2034 (USD Million)
List of Figures:
- Figure 1. U.S. Next-Generation Sequencing Library Preparation Market, 2020-2034 (USD Million)
- Figure 2. Integrated Ecosystem
- Figure 3. Research Methodology: Top-Down & Bottom-Up Price
- Figure 4. Market by Geography
- Figure 5. Porter's Five Forces
- Figure 6. Market by Sequencing Type
- Figure 7. U.S. Next-Generation Sequencing Library Preparation Market, by Sequencing Type, 2024 & 2034 (USD Million)
- Figure 8. Market by Product
- Figure 9. U.S. Next-Generation Sequencing Library Preparation Market, by Product, 2024 & 2034 (USD Million)
- Figure 10. Market by Application
- Figure 11. U.S. Next-Generation Sequencing Library Preparation Market, by Application, 2024 & 2034 (USD Million)
- Figure 12. Market by End Use
- Figure 13. U.S. Next-Generation Sequencing Library Preparation Market, by End Use, 2024 & 2034 (USD Million)
