PUBLISHER: Polaris Market Research | PRODUCT CODE: 1786887
PUBLISHER: Polaris Market Research | PRODUCT CODE: 1786887
The next generation sequencing sample preparation market size is expected to reach USD 16.57 billion by 2034, according to a new study by Polaris Market Research. The report "Next Generation Sequencing Sample Preparation Market Share, Size, Trends, Industry Analysis Report By Product & Service (Instruments, Consumables, Services), By Workflow, By Application, By End Use, By Region; Market Forecast, 2025-2034" gives a detailed insight into current market dynamics and provides analysis on future market growth.
Next generation sequencing (NGS) sample preparation is a critical step in the sequencing workflow that involves processing DNA or RNA samples to make them compatible with high-throughput sequencing platforms. The preparation usually begins with nucleic acid extraction, where DNA or RNA is isolated from biological samples such as blood, tissue, or cells. The extracted material is then quantified and assessed for purity using spectrophotometry or fluorometry. For RNA sequencing (RNA-seq), an additional step of converting RNA into complementary DNA (cDNA) is required. The DNA or cDNA is then fragmented into smaller pieces, either enzymatically or mechanically, to facilitate sequencing.
Next generation sequencing sample preparation is used across various applications, including whole genome sequencing, targeted DNA RNA sequencing, transcriptomics, epigenetics, and metagenomics. In clinical diagnostics, it enables the identification of genetic mutations linked to diseases, while in cancer research, it helps characterize tumor genomes. In infectious disease studies, NGS aids in pathogen detection and outbreak surveillance.
Advancements in library preparation kits and automated systems have streamlined the process, reducing hands-on time and improving reproducibility. NGS sample preparation is the foundation for generating high-quality sequencing data, enabling breakthroughs in genomics, personalized medicine, and biotechnology.
In terms of product & service, the consumables segment accounted for a major market share in 2024. Researchers and laboratories across clinical, academic, and pharmaceutical sectors heavily relied on reagents, kits, and other disposable materials due to the high frequency of sample preparation workflows.
Based on workflow, the library preparation & amplification segment held the largest share of the next generation sequencing (NGS) sample preparation market in 2024 due to its crucial role in enabling accurate and high-throughput sequencing.
In terms of application, the oncology segment held the largest market share in 2024 due to the ability of next generation sequencing sample preparation to uncover somatic mutations, identify tumor-specific biomarkers, and guide targeted therapies.
Based on end use, the pharma & biotech entities segment accounted for a major market share in 2024. These organizations drove substantial demand for sequencing sample preparation due to their extensive use of NGS technologies in drug discovery, biomarker identification, and companion diagnostics.
A few global key players in the NGS sample preparation market include Agilent Technologies, Inc.; BGI Genomics; Bio-Rad Laboratories, Inc.; Danaher Corporation; Eurofins Scientific; F. Hoffmann-La Roche Ltd; Illumina, Inc.; PerkinElmer Inc.; QIAGEN; and Thermo Fisher Scientific Inc.
Polaris Market Research has segmented the next generation sequencing sample preparation market report on the basis of product & service, workflow, application, end use, and region:
By Product & Service Outlook (Revenue, USD Billion, 2020-2034)
Instruments
Consumables
Services
By Workflow Outlook (Revenue, USD Billion, 2020-2034)
Nucleic Acid Extraction
Library Preparation & Amplification
Target Enrichment
Library Quantification/QC
By Application Outlook (Revenue, USD Billion, 2020-2034)
Oncology
Clinical Investigation
Reproductive Health
HLA Typing/Immune System Monitoring
Metagenomics, Epidemiology & Drug Development
Agrigenomics & Forensics
Consumer Genomics
By End Use Outlook (Revenue, USD Billion, 2020-2034)
Academic Research
Clinical Research
Hospitals & Clinics
Pharma & Biotech Entities
Other
By Regional Outlook (Revenue, USD Billion, 2020-2034)
North America
US
Canada
Europe
Germany
France
UK
Italy
Spain
Netherlands
Russia
Rest of Europe
Asia Pacific
China
Japan
India
Malaysia
South Korea
Indonesia
Australia
Vietnam
Rest of Asia Pacific
Middle East & Africa
Saudi Arabia
UAE
Israel
South Africa
Rest of Middle East & Africa
Latin America
Mexico
Brazil
Argentina
Rest of Latin America