U.S. Protein Purification and Isolation Market Size, Share, Trends, Industry Analysis Report By Product (Instruments, Consumables), By Technology, By Application, By End Use

Description

List of Tables

The U.S. Protein Purification and Isolation market size is expected to reach USD 8.66 billion by 2034, according to a new study by Polaris Market Research. The report "U.S. Protein Purification and Isolation Market Share, Size, Trends, Industry Analysis Report By Product (Instruments, Consumables), By Technology, By Application, By End Use; Market Forecast, 2025-2034" gives a detailed insight into current market dynamics and provides analysis on future market growth.

Protein purification and isolation are critical preparative techniques used to separate a specific protein of interest from a complex mixture to enable its functional or structural analysis. The U.S. protein purification and isolation market is growing due to the increasing focus on high-throughput and automated purification systems. These systems are designed to improve process efficiency, reduce manual errors, and enable consistent results in both academic and industrial workflows. The shift toward automation aligns with the growing demand for scalable and reproducible solutions in drug discovery and proteomics, reinforcing the importance of precision and speed in protein analysis.

The rising adoption of membrane-based and affinity chromatography technologies drives the market. These methods offer enhanced selectivity, shorter processing times, and greater adaptability to varying sample types, making them increasingly favorable across diverse applications. The preference for advanced purification matrices and formats continues to grow as researchers aim for higher purity and yield with minimal sample loss. This ongoing innovation in purification media and platforms supports the expanding scope of protein-based research and therapeutic development, further driving the evolution of the U.S. protein purification and isolation landscape.

U.S. Protein Purification and Isolation Market Report Highlights

In terms of product, the consumables segment led revenue generation in 2024, maintaining dominance through essential utilization in all protein purification process stages.

Based on technology, the electrophoresis segment witnesses strong growth potential, valued for its accurate protein characterization capabilities, including size determination and purity assessment.

In terms of application, the protein-protein interaction analysis segment emerged as the leading segment in 2024, reflecting increased research emphasis on deciphering disease-related molecular pathways and cellular processes.

Based on end use, the hospital segment is anticipated to experience the most rapid expansion during the forecast period, fueled by the growing adoption of proteomic solutions in clinical diagnostics and precision medicine applications.

A few key players in the U.S. protein purification and isolation market include Thermo Fisher Scientific, Bio-Rad Laboratories, Agilent Technologies, Promega Corporation, Charles River Laboratories, Revvity Inc., Creative Proteomics, Scripps Laboratories, Aalto Scientific, and Arvys Proteins Inc.

Polaris Market Research has segmented the U.S. protein purification and isolation market report on the basis of product, technology, application, and end use:

By Product Outlook (Revenue, USD Billion, 2020-2034)

Instruments

Consumables

Kits

Reagents

Columns

Magnetic Beads

Resins

Others

By Technology Outlook (Revenue, USD Billion, 2020-2034)

Ultrafiltration

Precipitation

Chromatography

Ion Exchange Chromatography

Affinity Chromatography

Reversed Phase Chromatography

Size Exclusion Chromatography

Hydrophobic Interaction Chromatography

Electrophoresis

Gel Electrophoresis

Isoelectric Focusing

Capillary Electrophoresis

Western Blotting

Others

By Application Outlook (Revenue, USD Billion, 2020-2034)

Drug Screening

Biomarker Discovery

Protein-Protein Interaction Studies

Diagnostics

By End Use Outlook (Revenue, USD Billion, 2020-2034)

Academic and Research Institutes

Hospitals

Pharmaceutical and Biotechnology Companies

CROs

By Regional Outlook (Revenue, USD Billion, 2020-2034)

North America

U.S.

Canada

Europe

Germany

France

Italy

Spain

Russia

Netherlands

Rest of Europe

Asia Pacific

China

India

Japan

South Korea

Indonesia

Malaysia

Vietnam

Australia

Rest of Asia Pacific

Latin America

Argentina

Brazil

Mexico

Rest of Latin America

Middle East & Africa

UAE

Saudi Arabia

Israel

South Africa

Rest of Middle East & Africa

Product Code: PM6199

1. Introduction

1.1. Report Description
- 1.1.1. Objectives of the Study
- 1.1.2. Market Scope
- 1.1.3. Assumptions
1.2. Stakeholders

2. Executive Summary

2.1. Market Highlights

3. Research Methodology

3.1. Overview
- 3.1.1. Data Mining
3.2. Data Sources
- 3.2.1. Primary Sources
- 3.2.2. Secondary Sources

4. U.S. Protein Purification and Isolation Market Insights

4.1. U.S. Protein Purification and Isolation Market - Market Snapshot
4.2. U.S. Protein Purification and Isolation Market Dynamics
- 4.2.1. Drivers and Opportunities
  - 4.2.1.1. Increasing R&D investments
  - 4.2.1.2. Increasing Automation & AI integration
- 4.2.2. Restraints and Challenges
  - 4.2.2.1. High initial capital investment and operational costs
4.3. Porter's Five Forces Analysis
- 4.3.1. Bargaining Power of Suppliers (Moderate)
- 4.3.2. Threats of New Entrants: (Low)
- 4.3.3. Bargaining Power of Buyers (Moderate)
- 4.3.4. Threat of Substitute (Moderate)
- 4.3.5. Rivalry among existing firms (High)
4.4. PESTEL Analysis
4.5. U.S. Protein Purification and Isolation Market Trends
4.6. Value Chain Analysis

5. U.S. Protein Purification and Isolation Market, by Product

5.1. Key Findings
5.2. Introduction
- 5.2.1. U.S. Protein Purification and Isolation Market, by Product, 2020-2034 (USD Billion)
5.3. Instruments
- 5.3.1. U.S. Protein Purification and Isolation Market, by Instruments, 2020-2034 (USD Billion)
5.4. Consumables
- 5.4.1. U.S. Protein Purification and Isolation Market, by Consumables, 2020-2034 (USD Billion)
5.5. Kits
- 5.5.1. U.S. Protein Purification and Isolation Market, by Kits, 2020-2034 (USD Billion)
5.6. Reagents
- 5.6.1. U.S. Protein Purification and Isolation Market, by Reagents, 2020-2034 (USD Billion)
5.7. Columns
- 5.7.1. U.S. Protein Purification and Isolation Market, by Columns, 2020-2034 (USD Billion)
5.8. Magnetic Beads
- 5.8.1. U.S. Protein Purification and Isolation Market, by Magnetic Beads, 2020-2034 (USD Billion)
5.9. Resins
- 5.9.1. U.S. Protein Purification and Isolation Market, by Resins, 2020-2034 (USD Billion)
5.10. Others
- 5.10.1. U.S. Protein Purification and Isolation Market, by Others, 2020-2034 (USD Billion)

6. U.S. Protein Purification and Isolation Market, by Technology

6.1. Key Findings
6.2. Introduction
- 6.2.1. U.S. Protein Purification and Isolation Market, by Technology, 2020-2034 (USD Billion)
6.3. Ultrafiltration
- 6.3.1. U.S. Protein Purification and Isolation Market, by Ultrafiltration, 2020-2034 (USD Billion)
6.4. Precipitation
- 6.4.1. U.S. Protein Purification and Isolation Market, by Precipitation, 2020-2034 (USD Billion)
6.5. Chromatography
- 6.5.1. U.S. Protein Purification and Isolation Market, by Chromatography, 2020-2034 (USD Billion)
6.6. Ion Exchange Chromatography
- 6.6.1. U.S. Protein Purification and Isolation Market, by Ion Exchange Chromatography, 2020-2034 (USD Billion)
- 6.6.2. Affinity Chromatography
  - 6.6.2.1. U.S. Protein Purification and Isolation Market, by Affinity Chromatography, 2020-2034 (USD Billion)
- 6.6.3. Reversed Phase Chromatography
  - 6.6.3.1. U.S. Protein Purification and Isolation Market, by Reversed Phase Chromatography, 2020-2034 (USD Billion)
- 6.6.4. Size Exclusion Chromatography
  - 6.6.4.1. U.S. Protein Purification and Isolation Market, by Size Exclusion Chromatography, 2020-2034 (USD Billion)
- 6.6.5. Hydrophobic Interaction Chromatography
  - 6.6.5.1. U.S. Protein Purification and Isolation Market, by Hydrophobic Interaction Chromatography, 2020-2034 (USD Billion)
6.7. Electrophoresis
- 6.7.1. U.S. Protein Purification and Isolation Market, by Electrophoresis, 2020-2034 (USD Billion)
- 6.7.2. Gel Electrophoresis
  - 6.7.2.1. U.S. Protein Purification and Isolation Market, by Gel Electrophoresis, 2020-2034 (USD Billion)
- 6.7.3. Isoelectric Focusing
  - 6.7.3.1. U.S. Protein Purification and Isolation Market, by Isoelectric Focusing, 2020-2034 (USD Billion)
- 6.7.4. Capillary Electrophoresis
  - 6.7.4.1. U.S. Protein Purification and Isolation Market, by Capillary Electrophoresis, 2020-2034 (USD Billion)
6.8. Western Blotting
- 6.8.1. U.S. Protein Purification and Isolation Market, by Western Blotting, 2020-2034 (USD Billion)
6.9. Others
- 6.9.1. U.S. Protein Purification and Isolation Market, by Others, 2020-2034 (USD Billion)

7. U.S. Protein Purification and Isolation Market, by Application

7.1. Key Findings
7.2. Introduction
- 7.2.1. U.S. Protein Purification and Isolation Market, by Application, 2020-2034 (USD Billion)
7.3. Drug Screening
- 7.3.1. U.S. Protein Purification and Isolation Market, by Drug Screening, 2020-2034 (USD Billion)
7.4. Biomarker Discovery
- 7.4.1. U.S. Protein Purification and Isolation Market, by Biomarker Discovery, 2020-2034 (USD Billion)
7.5. Protein-Protein Interaction Studies
- 7.5.1. U.S. Protein Purification and Isolation Market, by Protein-Protein Interaction Studies, 2020-2034 (USD Billion)
7.6. Diagnostics
- 7.6.1. U.S. Protein Purification and Isolation Market, by Diagnostics, 2020-2034 (USD Billion)

8. U.S. Protein Purification and Isolation Market, by End User

8.1. Key Findings
8.2. Introduction
- 8.2.1. U.S. Protein Purification and Isolation Market, by End User, 2020-2034 (USD Billion)
8.3. Academic and Pharmaceutical and Biotechnology Companies
- 8.3.1. U.S. Protein Purification and Isolation Market, by Academic and Pharmaceutical and Biotechnology Companies, 2020-2034 (USD Billion)
8.4. Hospitals
- 8.4.1. U.S. Protein Purification and Isolation Market, by Hospitals, 2020-2034 (USD Billion)
8.5. Pharmaceutical and Biotechnology Companies
- 8.5.1. U.S. Protein Purification and Isolation Market, by Pharmaceutical and Biotechnology Companies, 2020-2034 (USD Billion)
8.6. Pharmaceutical Companies
- 8.6.1. U.S. Protein Purification and Isolation Market, by Pharmaceutical Companies, 2020-2034 (USD Billion)
8.7. CROs
- 8.7.1. U.S. Protein Purification and Isolation Market, by CROs, 2020-2034 (USD Billion)

9. Competitive Landscape

9.1. Expansion and Acquisition Analysis
- 9.1.1. Expansion
- 9.1.2. Acquisitions
9.2. Partnerships/Collaborations/Agreements/Exhibitions

10. Company Profiles

10.1. Aalto Scientific
- 10.1.1. Company Overview
- 10.1.2. Financial Performance
- 10.1.3. Product Benchmarking
- 10.1.4. Recent Development
10.2. Agilent Technologies
- 10.2.1. Company Overview
- 10.2.2. Financial Performance
- 10.2.3. Product Benchmarking
- 10.2.4. Recent Development
10.3. Arvys Proteins Inc.
- 10.3.1. Company Overview
- 10.3.2. Financial Performance
- 10.3.3. Product Benchmarking
- 10.3.4. Recent Development
10.4. Bio-Rad Laboratories
- 10.4.1. Company Overview
- 10.4.2. Financial Performance
- 10.4.3. Product Benchmarking
- 10.4.4. Recent Development
10.5. Charles River Laboratories
- 10.5.1. Company Overview
- 10.5.2. Financial Performance
- 10.5.3. Product Benchmarking
- 10.5.4. Recent Development
10.6. Creative Proteomics
- 10.6.1. Company Overview
- 10.6.2. Financial Performance
- 10.6.3. Product Benchmarking
- 10.6.4. Recent Development
10.7. Promega Corporation
- 10.7.1. Company Overview
- 10.7.2. Financial Performance
- 10.7.3. Product Benchmarking
- 10.7.4. Recent Development
10.8. Revvity Inc.
- 10.8.1. Company Overview
- 10.8.2. Financial Performance
- 10.8.3. Product Benchmarking
- 10.8.4. Recent Development
10.9. Scripps Laboratories
- 10.9.1. Company Overview
- 10.9.2. Financial Performance
- 10.9.3. Product Benchmarking
- 10.9.4. Recent Development
10.10. Thermo Fisher Scientific Inc.
- 10.10.1. Company Overview
- 10.10.2. Financial Performance
- 10.10.3. Product Benchmarking
- 10.10.4. Recent Development