United States Endobronchial Ultrasound Biopsy Market Report by Product, Application, End Use, States and Company Analysis, 2025-2033

United States Endobronchial Ultrasound Biopsy Market Size and Forecast 2025-2033

United States Endobronchial ultrasound biopsy Market is expected to reach US$ 356.2 billion by 2033 from US$ 246.82 billion in 2024, with a CAGR of 4.16% from 2025 to 2033. The market for endobronchial ultrasound (EBUS) biopsies in the US is expected to grow gradually due to rising lung disease cases, expanding demand for minimally invasive diagnostics, and developments in imaging-guided biopsy technologies.

United States Endobronchial ultrasound biopsy Industry Overview

The market for endobronchial ultrasound (EBUS) biopsies in the US has grown in importance as the need for less invasive diagnostic procedures keeps growing. A vital tool for pulmonologists and oncologists, EBUS biopsy is a method for obtaining lymph node samples and detecting lung disorders. Adoption is being fueled by the need for precise, secure, and minimally intrusive diagnostic techniques because lung cancer is one of the nation's most serious health issues. For biopsies, traditional surgical techniques may entail greater risks, lengthier recovery times, and higher expenses. On the other hand, EBUS biopsy is a preferred option for patients and healthcare professionals alike due to its real-time imaging, accurate sample, and less patient discomfort.

In order to diagnose and assess the severity of respiratory disorders, including chronic obstructive pulmonary disease (COPD), tuberculosis, and lung and bronchus cancer, endobronchial ultrasound biopsy is used to take tissue or fluid samples from the lungs and surrounding lymph nodes without the need for traditional surgery. For example, according to the American Lung Association's 2024 statistics, 11.7 million Americans, or 4.6% of the adult population, were diagnosed with COPD in 2022. This means that a sizable patient base might need a diagnosis. In a similar vein, the 2022 update from the Australian Bureau of Statistics shows that persons 65 and older had a far higher chance of being diagnosed with COPD, with about one in fourteen (7.0%) receiving a diagnosis. Thus, the market for endobronchial ultrasonography biopsies may be driven by the increasing incidence of respiratory conditions.

One of the main factors driving the use of EBUS in diagnosis and staging is the rising incidence of lung cancer. It is anticipated that the growing number of lung cancer cases will fuel market expansion. The American Cancer Society (ACS) Cancer Statistics 2024, for example, projects that 2 million new instances of cancer would be detected in the US in 2024, up from 1.9 million in 2023. Lung and bronchus cancer are predicted to account for 234.5 thousand of the total cancer cases in 2024. Compared to conventional surgical biopsies, EBUS provides a less intrusive method of obtaining tissue samples. Therefore, since endobronchial ultrasonography biopsy is a minimally invasive treatment that can be carried out with local anesthetic and moderate sedation, the increasing number of lung cancer cases in the area is anticipated to drive the demand for this operation.

Additionally, in 2023, the United States spent USD 148 million on research and development for COPD, USD 595 million for tuberculosis, and USD 504 million for lung cancer, according to the Condition and Disease Categories (RCDC) May 2024 update. Thus, it is anticipated that the nation's strong investment in respiratory disease research will spur the creation of novel EBUS biopsy instruments, which will further support market expansion throughout the course of the projection period.

Key Factors Driving the United States Endobronchial ultrasound biopsy Market Growth

Rising Prevalence of Lung Diseases

The increasing prevalence of lung cancer, chronic obstructive pulmonary disease (COPD), and other respiratory illnesses in the United States is a significant driver of EBUS biopsy adoption. As these conditions often require accurate diagnosis and staging, healthcare providers are increasingly relying on EBUS biopsy to obtain precise tissue samples while minimizing risks associated with invasive surgeries. Early detection and accurate staging are critical for determining treatment pathways, particularly in lung cancer cases where outcomes depend on timely intervention. EBUS biopsy's ability to combine imaging with real-time tissue sampling makes it a preferred diagnostic tool. The growing patient population with respiratory disorders, combined with rising awareness of the benefits of minimally invasive diagnostics, is contributing to strong market demand.

Advancements in Diagnostic Technologies

Technological progress in imaging and biopsy tools has significantly boosted the reliability and accuracy of EBUS biopsy procedures. Enhanced ultrasound probes, better visualization systems, and refined biopsy needles now allow pulmonologists to reach and sample hard-to-access lymph nodes with greater precision. These advancements reduce the chances of diagnostic errors while improving patient safety and comfort. Additionally, integration of digital technologies, such as AI-assisted imaging and cloud-based diagnostic platforms, is streamlining workflows and enabling faster, more accurate analysis. Such innovations are not only improving clinical outcomes but also making EBUS procedures more appealing to healthcare providers who aim to deliver better patient care. As diagnostic technologies continue to evolve, the role of EBUS biopsy in routine clinical practice is expected to strengthen further.

Increasing Preference for Minimally Invasive Procedures

The broader healthcare shift toward minimally invasive diagnostic and treatment solutions is also fueling the adoption of EBUS biopsy in the United States. Patients and healthcare systems increasingly prioritize procedures that reduce recovery time, lower complication risks, and provide cost-effective outcomes. EBUS biopsy aligns with these needs by offering a safe, outpatient-friendly alternative to surgical biopsies, such as mediastinoscopy. Its ability to deliver accurate results with fewer complications has made it the standard of care for many diagnostic pathways. Additionally, supportive reimbursement frameworks for minimally invasive diagnostics are encouraging hospitals and clinics to integrate EBUS systems. As this trend continues, the demand for EBUS biopsy is expected to grow as part of the evolving patient-centered healthcare landscape.

Challenges in the United States Endobronchial ultrasound biopsy Market

High Cost of Equipment and Procedures

One of the key challenges facing the EBUS biopsy market in the U.S. is the high cost associated with equipment procurement, maintenance, and the procedure itself. Advanced imaging systems, biopsy needles, and supporting devices require significant investment by hospitals and clinics. For smaller healthcare facilities, these costs can be prohibitive, limiting widespread adoption. Additionally, although reimbursement policies support minimally invasive diagnostics, variations in coverage and out-of-pocket expenses for patients may restrict access. This financial barrier could slow down market penetration, particularly in regions with limited healthcare resources. Balancing affordability with the need for cutting-edge technology remains a major challenge for manufacturers and providers alike.

Requirement for Skilled Operators

Another challenge is the need for highly trained and skilled operators to perform EBUS biopsies effectively. The procedure requires precision, technical expertise, and familiarity with advanced imaging systems to ensure accurate tissue sampling and avoid complications. A shortage of trained pulmonologists and endoscopists with specialized EBUS expertise can limit the availability of the procedure, particularly outside major urban centers. Training programs are being developed to address this gap, but the learning curve remains steep for many healthcare professionals. Without sufficient operator proficiency, diagnostic accuracy and patient safety could be compromised, hindering the broader adoption of EBUS biopsy across the United States.

United States Endobronchial ultrasound biopsy Market Overview by States

Regional demand for EBUS biopsy in the U.S. is concentrated in states like California, Texas, New York, and Florida, where, strong healthcare infrastructure and high prevalence of lung diseases support market expansion. The following provides a market overview by States:

California Endobronchial ultrasound biopsy Market

California plays a leading role in the adoption of EBUS biopsy, supported by its advanced healthcare ecosystem and high concentration of specialized hospitals and research institutions. The state's large patient population and rising incidence of lung-related diseases create strong demand for minimally invasive diagnostic procedures. Academic centers and medical device innovators in California are also contributing to technological advancements and clinical research, further strengthening adoption. With supportive healthcare policies and reimbursement structures, providers across California are well-positioned to integrate EBUS biopsy into their diagnostic pathways. Additionally, the state's focus on innovation in medical technologies has encouraged collaborations between healthcare providers and manufacturers, making California a key hub for growth in the U.S. EBUS biopsy market.

Texas Endobronchial ultrasound biopsy Market

Texas is emerging as a significant market for EBUS biopsy due to its expanding healthcare sector and growing burden of respiratory diseases. Major cities such as Houston, Dallas, and Austin house world-class hospitals and cancer centers that are increasingly adopting EBUS systems to enhance diagnostic capabilities. The state's large and diverse population supports demand for advanced diagnostic tools, particularly in lung cancer detection and staging. Additionally, Texas' investment in healthcare infrastructure and strong presence of medical training centers are helping to expand physician expertise in EBUS procedures. Business-friendly policies and a focus on healthcare innovation further contribute to the market's growth. With rising adoption and expanding capabilities, Texas continues to strengthen its position in the U.S. EBUS biopsy market.

New York Endobronchial ultrasound biopsy Market

New York represents a dynamic market for EBUS biopsy, supported by its concentration of premier healthcare facilities, research institutions, and a high prevalence of respiratory illnesses. Hospitals and specialty clinics across New York City and other regions are integrating EBUS biopsy as part of their diagnostic protocols, particularly in oncology and pulmonology. The state benefits from strong academic-industry collaborations that foster innovation and adoption of advanced diagnostic technologies. Additionally, New York's robust reimbursement systems and patient-centered care initiatives make minimally invasive procedures more accessible. The presence of leading cancer treatment centers further enhances demand for precise diagnostic tools like EBUS biopsy. With these advantages, New York is expected to remain a key contributor to the U.S. EBUS biopsy market's growth.

Florida Endobronchial ultrasound biopsy Market

Florida has become an important market for EBUS biopsy, driven by its growing elderly population and high incidence of lung and respiratory conditions. Major metropolitan areas such as Miami, Orlando, and Tampa are seeing rising adoption of minimally invasive diagnostic solutions, including EBUS biopsy. The state's large network of hospitals and specialty clinics is increasingly turning to these technologies to improve diagnostic accuracy and patient outcomes. Florida also benefits from supportive healthcare policies and investments in advanced medical infrastructure. Moreover, the state's reputation as a hub for medical innovation and clinical trials further supports adoption. With an aging population and rising demand for patient-friendly diagnostic methods, Florida is poised to play a significant role in the expansion of the U.S. EBUS biopsy market.

Market Segmentations

Product

• EBUS Scopes
• EBUS Needles
• Ultrasound Processors and Imaging Systems
• Accessories

Application

• Cancer Diagnostic
• Infection Diagnostic
• Others

End Use

• Hospitals
• Ambulatory Surgical Centers (ASCs)
• Specialty Clinics

States

• California
• Texas
• New York
• Florida
• Illinois
• Pennsylvania
• Ohio
• Georgia
• New Jersey
• Washington
• North Carolina
• Massachusetts
• Virginia
• Michigan
• Maryland
• Colorado
• Tennessee
• Indiana
• Arizona
• Minnesota
• Wisconsin
• Missouri
• Connecticut
• South Carolina
• Oregon
• Louisiana
• Alabama
• Kentucky
• Rest of United States

All the Key players have been covered

• Overviews
• Key Person
• Recent Developments
• SWOT Analysis
• Revenue Analysis

Company Analysis:

• GE Healthcare
• Siemens Healthcare Private Limited
• Koninklijke Philips N.V.
• Boston Scientific Corporation
• Olympus Corporation
• Cook Group Incorporated
• FUJIFILM Holdings Corporation
• Medi-Globe Technologies GmbH