ALLOGENEIC CELL THERAPY MARKET: OVERVIEW
As per Roots Analysis, the global allogenic cell therapy market is estimated to grow from USD 0.98 billion in the current year to USD 2.74 billion by 2035, at a CAGR of 5.9% during the forecast period, till 2035.
The market sizing and opportunity analysis has been segmented across the following parameters:
Type of Cell Therapy
- Stem Cell
- Virus-Specific T-Cell
- Regulatory T-Cell
Source of Cell
- Bone Marrow / Matrix
- Adipose Tissue
- Peripheral Blood
- Umbilical Cord
- Placenta
- Others
Target Indication
- Infectious Diseases
- Chronic Heart Failure
- Crohn's Disease
- Ischemic Stroke
- Hematological Cancer
- Bone Diseases
- Critical Limb Ischemia
- Graft versus Host Disease
- Duchenne Muscular Dystrophy
- Epidermolysis Bullosa
- Diabetic Foot Ulcer
- Others
Therapeutic Area
- Post-Transplant Infections
- Cardiovascular Disorders
- Autoimmune / Inflammatory Disorders
- Cerebrovascular Disorders
- Oncological Disorders
- Musculoskeletal Disorders
- Neurological Disorders
- Genetic Disorders
- Others
Key Geographical Regions
- North America
- Europe
- Asia-Pacific and Rest of the World
ALLOGENEIC CELL THERAPY MARKET: GROWTH AND TRENDS
Cell therapy refers to the administration of engineered cells into a patient's body in order to replace the damaged tissues or to modulate the cell functioning through direct interaction or expression of factors. Depending on its source, cell therapies can either be autologous (derived from the patient's own body) or allogeneic (derived from a healthy donor).
Allogenic cell therapy, often referred to as "off-the-shelf" cell therapy, is a form of regenerative medicine that involves the use of cells from a donor, rather than the patient themselves. These cells can be derived from various sources, such as bone marrow, umbilical cord blood, or induced pluripotent stem cells (iPSCs). Unlike autologous cell therapy, where a patient's own cells are used, allogenic cell therapy provides several distinct advantages. One of the key applications of allogeneic cell therapy is in the treatment of various diseases, such as cancer, autoimmune disorders, and degenerative conditions. In fact, according to the Alliance for Regenerative Medicine, the number of clinical trials being conducted for allogeneic cell-based cancer therapies increased by 30% over the past five years. Further, it is worth mentioning that these cells can be genetically modified to enhance their therapeutic properties, making them more effective at targeting and destroying disease cells or promoting tissue repair.
ALLOGENEIC CELL THERAPY MARKET: KEY INSIGHTS
The report delves into the current state of the allogeneic cell therapy market and identifies potential growth opportunities within the industry. Some key findings from the report include:
- Over 480 allogeneic cell therapies are either approved or being investigated in research studies by more than 190 players; the market landscape features the presence of both established players and new entrants.
- The majority of the clinical-stage allogeneic cell therapies are being evaluated in phase II trials; these therapies are being derived from different sources of cells and target multiple disease indications.

- More than 365 clinical trials (with over 18,000 enrolled patients) are currently underway to investigate allogeneic cell therapies across different geographies.
- The rising interest of stakeholders in this domain is reflected in the wide array of partnerships established by allogeneic cell therapy developers with various international and indigenous partners.
- Having realized the opportunity in this segment, several investors have invested around USD 8.8 billion (across 120 funding instances), in the past five years; the maximum amount was invested through venture capital rounds.
- Various KOLs affiliated to academic / medical / commercial organizations are evaluating the efficiency of allogeneic cell therapies in different disease indications.
- Driven by the rising incidence of chronic diseases and growing demand for novel allogeneic cell therapies, this market is anticipated to grow at a CAGR of 5.9%, till 2035.

- The projected future opportunity for allogeneic cell therapies is likely to be well distributed across different types of target indications, therapeutic areas and key geographical regions.
ALLOGENEIC CELL THERAPY MARKET: KEY SEGMENTS
Regulatory T-Cell Therapies is the Fastest Growing Segment of the Allogeneic Cell Therapy Market
Based on the type of cell therapy, the global market for allogeneic cell therapy is segmented into stem cell, virus-specific T cell and regulatory T-cell therapies. Currently, the majority share of the allogeneic cell therapy market is captured by stem cell therapies. It is worth mentioning that the regulatory T-cell therapies segment is likely to grow at a higher CAGR (~ 23%) in the coming years.
By Source of Cell, Bone Marrow / Matrix Segment Dominates the Global Allogeneic Cell Therapy Market
Based on the source of cells, the market is segmented into bone marrow / matrix, adipose tissue, peripheral blood, umbilical cord, placenta and others. Currently, the market is dominated by bone marrow / matrix-derived allogenic cell therapies, capturing the highest proportion of the allogeneic cell therapy market. It is worth highlighting that the global allogeneic cell therapy market for the adipose tissue-derived therapies segment is likely to grow at a relatively higher CAGR.
Infectious Diseases Segment is Likely to Hold the Largest Share of the Allogeneic Cell Therapy Market During the Forecast Period
Based on the target indication, the market is segmented into infectious diseases, chronic heart failure, Crohn's disease, ischemic stroke, hematological cancer, bone disease, critical limb ischemia, graft versus host disease, Duchenne muscular dystrophy, epidermolysis bullosa, diabetic foot ulcer and others. At present, the infectious diseases segment holds the majority share of the global allogeneic cell therapy market. Notably, epidermolysis bullosa target indication segment is likely to grow at a relatively higher CAGR.
By Therapeutic Area, Allogeneic Cell Therapies for Post-Transplant Infections are Likely to Dominate the Market During the Forecast Period
Based on the therapeutic area, the global market for allogeneic cell therapy is distributed across post-transplant infections, cardiovascular disorders, autoimmune / inflammatory disorders, cerebrovascular disorders, oncological disorders, musculoskeletal disorders, neurological disorders, genetic disorders and others. Currently, allogeneic cell therapies for post-transplant infections and cardiovascular disorders dominate the overall market. However, the market for cell therapies used in autoimmune / inflammatory disorders is likely to grow at a relatively higher CAGR.
North America Accounts for the Largest Share of the Market
Based on the key geographical regions, the market is segmented into North America, Europe, and Asia-Pacific and Rest of the World. In the current scenario, North America is likely to capture the largest market share.
Example Players in the Allogeneic Cell Therapy Market
- Artiva Biotherapeutics
- Allogene Therapeutics
- Atara Biotherapeutics
- Cellenkos
- Cell2Cure
- Celularity
- Cellular Biomedicine Group
- CHABiotech
- CRISPR Therapeutics
- Fate Therapeutics
- Fundamenta Therapeutics
- GC Cell
- Hope Biosciences
- Immunity Bio
- Mesoblast
- Nanjing Bioheng Biotech
- Orca Bio
- Pluristem Therapeutics
- Poseida Therapeutics
- Stemedica Cell Technologies
ALLOGENEIC CELL THERAPY MARKET: RESEARCH COVERAGE
- Market Sizing and Opportunity Analysis: The report features an in-depth analysis of the global allogeneic cell therapy market, focusing on key market segments, including [A] type of cell therapy, [B] source of cell, [C] target indication, [D] therapeutic area and [E] key geographical regions.
- Allogeneic Cell Therapies Market Landscape: A comprehensive evaluation of allogeneic cell therapies, based on several relevant parameters, such as [A] year of establishment, [B] company size, [C] location of headquarters, [D] phase of development, [E] route of administration, [F] type of cell therapy, [G] source of cell, [H] dosing frequency, [I] type of therapy, [J] target patient segment, [K] target indication and [L] therapeutic area.
- Partnerships and Collaborations: An insightful analysis of the deals inked by stakeholders in allogeneic cell therapy domain, based on several parameters, such as [A] year of partnership, [B] type of partnership, [C] type of cell therapy, [D] therapeutic area, [E] type of partner, [F] most active players and [G] geographical distribution of partnership activity.
- Funding and Investment Analysis: An in-depth analysis of the fundings raised by companies engaged in this domain, based on relevant parameters, such as [A] year of investment, [B] amount invested, [C] type of funding, [D] type of investor, [E] type of therapy, [F] geographical distribution and [G] most active players.
- Clinical Trial Analysis: An insightful analysis of clinical trials related to allogeneic cell therapies, based on several parameters, such as [A] trial registration year, [B] trial status, [C] trial phase, [D] study design, [E] type of sponsor, [F] geography and [G] most active industry and non-industry players.
- Key Opinion Leaders (KOLs]: An in-depth analysis that emphasizes the key opinion leaders investigating clinical trials related to allogeneic cell therapies, considering various parameters, such as [A] type of KOL, [B] qualification, [C] type of organization, [D] affiliated organization, [E] geographical location of KOLs and [F] target disease indication.
KEY QUESTIONS ANSWERED IN THIS REPORT
- How many companies are currently engaged in this market?
- Which are the leading companies in this market?
- What factors are likely to influence the evolution of this market?
- What is the current and future market size?
- What is the CAGR of this market?
- How is the current and future market opportunity likely to be distributed across key market segments?
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