Nucleic Acid Isolation and Purification Market: Overview
As per Roots Analysis, the nucleic acid isolation and purification market is estimated to grow from USD 5.41 billion in the current year to USD 10.52 billion by 2035, at a CAGR of 6.9% during the forecast period, till 2035.
Nucleic Acid Isolation and Purification Market: Growth and Trends
The nucleic acid isolation and purification market is experiencing rapid growth globally, fueled by the increasing adoption of next-generation sequencing technologies, and heightened interest of players in molecular biology. Further, the rising research and development investments aimed at the discovery and development of RNA therapeutics are also contributing to market growth. Furthermore, the rising prevalence of chronic diseases is contributing to the higher demand for nucleic acid isolation and purification products. According to a report by the Centers for Disease Control and Prevention, more than 90% of adults aged 65 and older suffer from at least one chronic condition. In addition, data from the World Health Organization indicates that roughly 75% of deaths worldwide are attributed to chronic diseases.
The market is also propelled by the growing need for personalized medicine, which relies heavily on patient-specific genetic profiling. In addition, this genetic profiling necessitates efficient extraction of circulating free DNA, miRNA, and exosomes from various sample types. Additionally, advancements in technology and automation in extraction methods are further driving market expansion. Techniques such as magnetic-based purification and microfluidic systems considerably reduce processing times and lessen errors. Many companies in the market are actively engaging in initiatives, including the introduction of innovative products and forming partnerships and collaborations to create advanced purification solutions. As an increasing number of industry players concentrate on developing groundbreaking drug discovery and diagnostic solutions from a diverse range of sample types, it is anticipated that the nucleic acid isolation and purification sector will see a robust compound annual growth rate in the future.
Growth Drivers: Strategic Enablers of Market Expansion
The rise in demand for clinical-grade NGS has increased the necessity for high-quality nucleic acid extraction, especially in oncology processes and liquid biopsy applications. National genomics initiatives and a boost in research and development funding in molecular biology enhance sample throughput and facilitate multi-omics research. The automation of workflows, the use of high-throughput platforms, advancements in synthetic biology, and the application of CRISPR are also speeding up the adoption by enhancing efficiency and reproducibility.
Market Challenges: Critical Barriers Impeding Progress
While the global nucleic acid purification market is experiencing substantial growth, there are certain restraints that can hinder the growth of this industry. The expensive nature of instruments, reagents, and kits restricts availability, particularly for smaller laboratories and emerging markets. Further, cin the supply chain for resins and silica, combined with limited access in developing areas, obstructs expansion. Further, stringent regulations, variability in samples, a shortage of skilled workers, and waste disposal mandates also introduce operational challenges in the nucleic acid purification domain.
Nucleic Acid Isolation and Purification Market: Key Insights
The report delves into the current state of the nucleic acid isolation and purification market and identifies potential growth opportunities within industry. Some key findings from the report include:
- At present, ~370 companies are engaged in offering nucleic acid isolation and purification products across the globe; notably, close to 45% of such companies are based in Asia-Pacific region.

- ~35% of the nucleic acid isolation and purification providers are offering instruments for extraction of DNA / RNA from a variety of sample types, including whole blood cells, cell-free samples, cultured cells and FFPE tissues.
- The growing incidence of infectious diseases coupled with rising adoption of automation, drives the market for nucleic acid isolation and purification, positioning it for steady growth in the foreseeable future.
- Given the advancements in molecular diagnostics and genomics research, the market for nucleic acid isolation and purification is anticipated to grow at an annualized rate (CAGR) of 6.9% till 2035.
- Currently, product types that can be used for nucleic acid extraction from whole blood cells occupy majority share of the market; further, the extraction is primarily intended for applied and infectious disease testing purposes.
- At present, majority of the nucleic acid isolation and purification market is captured by academic end users; notably, North America captures the largest share of the market.
- The US nucleic acid isolation and purification market, driven by rising prevalence of chronic disorders and interest in molecular diagnostics is anticipated to grow at a CAGR of 6.8% by 2035.

- The nucleic acid isolation and purification market is likely to grow at an annualized rate (CAGR) of ~6.9%, till 2035; majority of the market share (~30%) is expected to be captured by the US.
- Given the rising interest in molecular diagnostics, along with the rising R&D expenditure and technological advancements, the nucleic acid isolation and purification industry is well-positioned for future growth.
Nucleic Acid Purification Market
The market sizing and opportunity analysis has been segmented across the following parameters:
By Type of Product
- Kits
- Reagents
- Instruments
By Type of Nucleic Acid
By Type of Solution
By Type of Purification Method
- Magnetic based
- Column based
- Reagent based
- Others
By Type of Sample
- Whole Blood Cells
- Cultured Cells
- Bacteria
- Mammalian Cells
- Yeast
- FFPE
- Brain and Kidney
- Tissues
- Other Tissues
- Plasma
- Urine
- Other Cell free Samples
- Saliva
- Others
By Type of Process
- Upstream Processing
- Downstream Processing
- PCR
- dPCR
- NGS
By Type of Application
- Oncology Research
- Oncology Testing
- Applied Testing
- Human Identification (HID)
- Infectious Disease Testing
- Microbiome Testing
- Other Applications
By End User
- Biopharma
- CDMO
- CRO
- CMO
- Academia
- Research Labs
- Cancer Centers
- University Hospitals
- Core Labs
- Government Labs
- Pathogen Reference Labs
By Geographical Regions
- North America
- US
- Canada
- Europe
- Germany
- France
- Italy
- UK
- Switzerland
- Rest of Europe
- Asia-Pacific and Rest of the World
- China
- Japan
- South Korea
- India
- Australia
- Rest of Asia-Pacific
- Middle East and North Africa
- Saudi Arabia
- United Arab Emirates
- Rest of Middle East & North Africa
- Latin America
- Brazil
- Argentina
- Rest of Latin America
Nucleic Acid Isolation and Purification Market: Key Segments
Kits Account for the Largest Nucleic Acid Isolation and Purification Market Share
According to the nucleic acid isolation and purification market analysis, the kits segment represents approximately 65% of the market share. This increase is attributed to their cost-effectiveness and easy accessibility in comparison to instruments, which involve considerable initial expenses and ongoing maintenance fees. Further, the kits segment is expected to experience a higher compound annual growth rate (CAGR) in the future, driven by their growing use in various diagnostic applications, including infectious disease testing, oncology testing, and microbiome testing among others.
Magnetic Purification Segment Hold the Highest Share in the Future
As per the forecast for the nucleic acid isolation and purification market, the segment focusing on magnetic purification solutions leads the market because this method provides automation compatibility, rapid processing, efficiency, and high purity levels. The nucleic acid extraction solutions utilizing magnetic purification are expected to experience a significant growth rate over the next decade due to their advantages and versatility across various sample types.
North America Dominates the Market by Securing Highest Share
North America holds over 40% of the market share for nucleic acid isolation and purification. Key factors driving the region's dominance in this field include increasing healthcare spending in the US, advanced infrastructure, an extensive network of laboratories, and a rising incidence of infectious diseases and genetic conditions.
Primary Research Overview
Discussions with multiple stakeholders in this domain influenced the opinions and insights presented in this study. The market report includes transcripts of the following other third-party discussions:
- Senior Vice President, Small Company in the US
- Head of Sales, Small Company in Germany
- Business Development Manager, Mid-sized Company in the US
- Business Development Executive, Mid-sized Company in Spain
- Business Development Manager, Mid-sized Company in Spain
- Business Manager, Small Company in Germany
- Assistant Manager, Mid-sized Company in India
- Marketing Manager, Small Company in the US
- Product Manager, Small Company in Netherlands
- Sales Representative, Mid-sized Company in China
Example Players in Nucleic Acid Purification Market
- Bio-Rad
- Danaher
- Macherey-Nagel
- Merck KgaA
- Norgen Biotek
- Perkin Elmer
- Promega
- Qiagen
- Roche
- Thermo Fisher Scientific
Nucleic Acid Purification Market: Research Coverage
- Market Sizing and Opportunity Analysis: The report features an in-depth analysis of the nucleic acid purification market, focusing on key market segments, including [A] type of product, [B] type of nucleic acid, [C] type of solution, [D] type of purification method, [E] type of sample, [F] type of process, [G] type of application, [H] end user and [I] geographical regions, and [J] leading players.
- Market Landscape: A detailed overview of the overall nucleic acid isolation and purification product providers market landscape, along with information on several relevant parameters, such as [A] year of establishment, [B] company size, [C] location of headquarters, [D] type of product, [E] type of nucleic acid, [F] type of sample, [G] type of solution, [H] type of purification method, [I] type of process, [J] end user and [K] type of application.
- Company Profiles: In-depth profiles of prominent players North America, Europe and Asia-Pacific that are engaged in offering nucleic acid isolation and purification products based on [A] year of establishment, [B] location of headquarters, [C] product portfolio, [D] recent developments and [E] an informed future outlook.
- Market Impact Analysis: An in-depth analysis of the factors that can impact the growth of the global nucleic acid purification market. It also features identification and analysis of [A] key drivers, [B] potential restraints, [C] emerging opportunities, and [D] existing challenges.
Key Questions Answered in this Report
- Which are the leading companies in nucleic acid purification market?
- Which region dominates the nucleic acid purification market?
- What are the key trends observed in the nucleic acid purification market?
- What factors are likely to influence the evolution of this market?
- What are the primary challenges faced by nucleic acid purification?
- What is the current and future market size?
- What is the CAGR of this market?
- How is the current and future market opportunity likely to be distributed across key market segments?
Reasons to Buy this Report
- The report provides a comprehensive market analysis, offering detailed revenue projections of the overall market and its specific sub-segments. This information is valuable to both established market leaders and emerging entrants.
- The report offers stakeholders a comprehensive overview of the market, including key drivers, barriers, opportunities, and challenges. This information empowers stakeholders to stay abreast of market trends and make data-driven decisions to capitalize on growth prospects.
- The report can aid businesses in identifying future opportunities in any sector. It also helps in understanding if those opportunities are worth pursuing.
- The report helps in identifying customer demand by understanding the needs, preferences, and behavior of the target audience in order to tailor products or services effectively.
- The report equips new entrants with requisite information regarding a particular market to help them build successful business strategies.
- The report allows for more effective communication with the audience and in building strong business relations.
Additional Benefits
- Complementary PPT Insights Pack
- Complimentary Excel Data Packs for all Analytical Modules in the Report
- 15% Free Content Customization
- Detailed Report Walkthrough Session with Research Team
- Free Updated report if the report is 6-12 months old or older