Downstream Processing Global Market Report 2024

Description

“Downstream Processing Global Market Report 2024 ” from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on downstream processing market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

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Where is the largest and fastest growing market for downstream processing? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? “The downstream processing market global report ” from The Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

Scope

Markets Covered:

1) By Product: Centrifuges; Dryers; Chromatography Systems; Filters; Evaporators; Other Products
2) By Technique: Purification Techniques; Solid-Liquid Separation; Clarification Or Concentration
3) By Application: Monoclonal Antibody Production; Vaccine Production; Insulin Production; Immunoglobulin Production; Erythropoietin Production; Other Applications
Companies Mentioned: Sartorius AG; General Electric Company; Merck KGaA; Thermo Fisher Scientific Inc.; Danaher Corporation
Countries: Australia; Brazil; China; France; Germany; India; Indonesia; Japan; Russia; South Korea; UK; USA; Canada; Italy; Spain
Regions: Asia-Pacific; Western Europe; Eastern Europe; North America; South America; Middle East; Africa
Time series: Five years historic and ten years forecast.
Data: Ratios of market size and growth to related markets, GDP proportions, expenditure per capita,
Data segmentations: country and regional historic and forecast data, market share of competitors, market segments.
Sourcing and Referencing: Data and analysis throughout the report is sourced using end notes.
Delivery format: PDF, Word and Excel Data Dashboard.

Executive Summary

Downstream processing involves the retrieval and purification of a drug substance (DS) derived from natural sources such as animal or bacterial cells. It delineates the sequence of steps essential to generate a pure and uniform protein product from biological components such as cells, tissue culture fluid, or plant tissues.

Key products utilized in downstream processing encompass centrifuges, dryers, chromatography systems, filters, evaporators, and others. Various techniques are applied, including purification methods, solid-liquid separation, and clarification or concentration. Centrifuges are devices that leverage centrifugal force to separate materials based on different densities, eliminate moisture, or replicate the effects of gravity. They find applications in diverse areas such as monoclonal antibody production, vaccine production, insulin production, immunoglobulin production, erythropoietin production, and more.

The downstream processing market research report is one of a series of new reports from The Business Research Company that provides downstream processing market statistics, including downstream processing industry global market size, regional shares, competitors with a downstream processing market share, detailed downstream processing market segments, market trends and opportunities, and any further data you may need to thrive in the downstream processing industry. This downstream processing market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The downstream processing market size has grown rapidly in recent years. It will grow from $27.19 billion in 2023 to $31.07 billion in 2024 at a compound annual growth rate (CAGR) of 14.3%. The historical period's growth can be ascribed to the growth of biopharmaceutical investments, the enforcement of strict regulatory standards, the global expansion of biopharmaceutical production, and the escalating prevalence of chronic diseases.

The downstream processing market is poised for rapid expansion in the coming years, reaching $51.09 billion by 2028 with a compound annual growth rate (CAGR) of 13.2%. This projected growth in the forecast period is attributed to the increasing demand for biopharmaceuticals, a heightened focus on sustainable and eco-friendly processing, growing collaborations and partnerships, the sustained adoption of continuous bioprocessing, and an escalating demand for personalized medicines. Key trends anticipated in the forecast period include the integration of digitalization and Industry 4.0, technological advancements, the utilization of single-use systems, the expansion of the biopharmaceutical industry, and the widespread adoption of continuous processing.

The anticipated increase in healthcare expenditure is poised to be a driving force for the future expansion of the downstream processing market. Healthcare expenditure encompasses all spending related to health services, family planning activities, nutrition initiatives, and emergency aid specifically allocated for health-related purposes. This heightened expenditure is expected to bolster the sales of downstream processing, a pivotal component in extracting drug substances (DS) from natural sources such as bacterial or animal cells and subsequently purifying the drug substance. According to the 2021-2030 National Health Expenditure (NHE) report by the Centers for Medicare & Medicaid Services in the United States, as of March 2022, the annual increase in national health spending is projected to average 5.1% between 2021 and 2030, reaching an approximate total of $6.8 trillion by 2030. Over the same period, Medicare expenditures are expected to grow at a 7.2% annual rate, while Medicaid spending is projected to increase at a 5.6% annual rate. Thus, the escalating healthcare expenditure significantly contributes to the downstream processing market's growth.

The anticipated growth in the biopharmaceutical sector is expected to drive the future expansion of the downstream processing market. The biopharmaceutical sector, a segment of the pharmaceutical industry specializing in the development, manufacturing, and commercialization of drugs and therapies derived from biological sources, is set to increase the demand for downstream processing (DSP). DSP is a crucial stage in the biopharmaceutical manufacturing process, responsible for isolating, purifying, and concentrating the desired drug substance from the complex mixture obtained after upstream processing. For instance, in June 2023, the European Federation of Pharmaceutical Industries and Associations (EFPIA), a European trade association representing the pharmaceutical industry, reported that the total pharmaceutical production in Europe amounted to $384,200 million (€340,000 million) in 2022, reflecting an increase of approximately 4.95% from $366,267 million (€323,950 million) in 2021. Therefore, the rising demand in the biopharmaceutical sector is a key driver for the downstream processing market's growth.

A prominent trend gaining traction is the emphasis on product innovations. Leading companies in the market are dedicated to developing new technological solutions as part of their strategy to solidify their market presence. For example, in September 2022, Tosoh Bioscience LLC, a global chemical and specialty materials company based in the United States, introduced the Octave BIO Multi-Column Chromatography (MCC) system. This innovative system serves as a comprehensive solution for downstream process intensification, specifically designed for advanced biomolecule purification processes. Its modular design allows flexibility to accommodate diverse requirements, offering advantages such as resin and buffer cost savings.

A key focus of major companies in the downstream processing market is on pioneering solutions, including the implementation of flow cells to drive revenue growth. A flow cell is a specialized container designed for the continuous flow of liquid samples. For instance, in October 2023, SCHOTT AG, a Germany-based technology group specializing in specialty glass and glass-ceramics, launched ViewCell. This new component aims to facilitate safe and continuous process control, optimizing downstream operations in the biopharmaceutical industry. The flexibility provided by the viewcell flow cell is expected to enhance the efficiency of downstream processes in the biopharmaceutical industry.

In January 2023, Astea Bio separations, a UK-based provider of bioseparation and purification technologies, completed the acquisition of Delta Precision Ltd. for an undisclosed amount. This acquisition positions Astea Bio separations to strengthen its existing portfolio of bioprocessing resins, reusable columns, and prepacked single-use columns by incorporating a wide range of high-performance chromatography columns for biomanufacturing. Delta Precision Ltd., a UK-based manufacturer of advanced chromatography columns, produces products for various applications, including protein purification, vaccine production, and drug development.

Major companies operating in the downstream processing market report are Sartorius AG, General Electric Company, Merck KGaA, Thermo Fisher Scientific Inc., Danaher Corporation, Repligen Corporation, Minnesota Mining and Manufacturing Company, Lonza Group Ltd., Eppendorf AG, Corning Corporation, Ferner PLC, Ashai Kasei Corporation, Finesse Solutions Inc., MilliporeSigma, Illumina Inc., Pall Corporation, Bio-Rad Laboratories, Charles River Laboratories International Inc., Waters Corporation, Becton Dickinson and Company (BD), Entegris Inc., Novasep, Avantor Sciences, Tecan Group, Agilent Technologies, Bracco S.p.A., Boehringer Ingelheim International GmbH, Eisai Co. Ltd., Novo Nordisk A/S, Ahlstrom-Munksjo Oyj, Grifols S.A., GenScript Biotech Corporation

North America was the largest region in the downstream processing market in 2023. Asia-Pacific is expected to be the fastest-growing region in the global downstream processing market report during the forecast period. The regions covered in the downstream processing market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

The countries covered in the downstream processing market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain

The downstream processing market consists of revenues earned by entities by providing downstream processing services such as cell separation, filtration, product recovery, extraction of products, and more. The market value includes the value of related goods sold by the service provider or included within the service offering. The Downstream processing market also includes sales of small-scale fermenters, pilot-scale fermenters, centrifuges, and membrane filtration systems which are used in providing downstream processing services. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Product Code: r11686

1. Executive Summary

2. Downstream Processing Market Characteristics

3. Downstream Processing Market Trends And Strategies

4. Downstream Processing Market - Macro Economic Scenario

4.1. Impact Of High Inflation On the Market
4.2. Ukraine-Russia War Impact On the Market
4.3. COVID-19 Impact On the Market

5. Global Downstream Processing Market Size and Growth

5.1. Global Downstream Processing Market Drivers and Restraints
- 5.1.1. Drivers Of The Market
- 5.1.2. Restraints Of The Market
5.2. Global Downstream Processing Historic Market Size and Growth, 2018 - 2023, Value ($ Billion)
5.3. Global Downstream Processing Forecast Market Size and Growth, 2023 - 2028, 2033F, Value ($ Billion)

6. Downstream Processing Market Segmentation

6.1. Global Downstream Processing Market, Segmentation By Product, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
Centrifuges
Dryers
Chromatography Systems
Filters
Evaporators
Other Products
6.2. Global Downstream Processing Market, Segmentation By Technique, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
Purification Techniques
Solid-Liquid Separation
Clarification Or Concentration
6.3. Global Downstream Processing Market, Segmentation By Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
Monoclonal Antibody Production
Vaccine Production
Insulin Production
Immunoglobulin Production
Erythropoietin Production
Other Applications

7. Downstream Processing Market Regional And Country Analysis

7.1. Global Downstream Processing Market, Split By Region, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
7.2. Global Downstream Processing Market, Split By Country, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

8. Asia-Pacific Downstream Processing Market

8.1. Asia-Pacific Downstream Processing Market Overview
Region Information, Impact Of COVID-19, Market Information, Background Information, Government Initiatives, Regulations, Regulatory Bodies, Major Associations, Taxes Levied, Corporate Tax Structure, Investments, Major Companies
8.2. Asia-Pacific Downstream Processing Market, Segmentation By Product, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
8.3. Asia-Pacific Downstream Processing Market, Segmentation By Technique, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
8.4. Asia-Pacific Downstream Processing Market, Segmentation By Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

9. China Downstream Processing Market

9.1. China Downstream Processing Market Overview
9.2. China Downstream Processing Market, Segmentation By Product, Historic and Forecast, 2018-2023, 2023-2028F, 2033F,$ Billion
9.3. China Downstream Processing Market, Segmentation By Technique, Historic and Forecast, 2018-2023, 2023-2028F, 2033F,$ Billion
9.4. China Downstream Processing Market, Segmentation By Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F,$ Billion

10. India Downstream Processing Market

10.1. India Downstream Processing Market, Segmentation By Product, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
10.2. India Downstream Processing Market, Segmentation By Technique, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
10.3. India Downstream Processing Market, Segmentation By Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

11. Japan Downstream Processing Market

11.1. Japan Downstream Processing Market Overview
11.2. Japan Downstream Processing Market, Segmentation By Product, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
11.3. Japan Downstream Processing Market, Segmentation By Technique, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
11.4. Japan Downstream Processing Market, Segmentation By Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

12. Australia Downstream Processing Market

12.1. Australia Downstream Processing Market, Segmentation By Product, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
12.2. Australia Downstream Processing Market, Segmentation By Technique, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
12.3. Australia Downstream Processing Market, Segmentation By Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

13. Indonesia Downstream Processing Market

13.1. Indonesia Downstream Processing Market, Segmentation By Product, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
13.2. Indonesia Downstream Processing Market, Segmentation By Technique, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
13.3. Indonesia Downstream Processing Market, Segmentation By Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

14. South Korea Downstream Processing Market

14.1. South Korea Downstream Processing Market Overview
14.2. South Korea Downstream Processing Market, Segmentation By Product, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
14.3. South Korea Downstream Processing Market, Segmentation By Technique, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
14.4. South Korea Downstream Processing Market, Segmentation By Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

15. Western Europe Downstream Processing Market

15.1. Western Europe Downstream Processing Market Overview
15.2. Western Europe Downstream Processing Market, Segmentation By Product, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
15.3. Western Europe Downstream Processing Market, Segmentation By Technique, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
15.4. Western Europe Downstream Processing Market, Segmentation By Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

16. UK Downstream Processing Market

16.1. UK Downstream Processing Market, Segmentation By Product, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
16.2. UK Downstream Processing Market, Segmentation By Technique, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
16.3. UK Downstream Processing Market, Segmentation By Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

17. Germany Downstream Processing Market

17.1. Germany Downstream Processing Market, Segmentation By Product, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
17.2. Germany Downstream Processing Market, Segmentation By Technique, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
17.3. Germany Downstream Processing Market, Segmentation By Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

18. France Downstream Processing Market

18.1. France Downstream Processing Market, Segmentation By Product, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
18.2. France Downstream Processing Market, Segmentation By Technique, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
18.3. France Downstream Processing Market, Segmentation By Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

19. Italy Downstream Processing Market

19.1. Italy Downstream Processing Market, Segmentation By Product, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
19.2. Italy Downstream Processing Market, Segmentation By Technique, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
19.3. Italy Downstream Processing Market, Segmentation By Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

20. Spain Downstream Processing Market

20.1. Spain Downstream Processing Market, Segmentation By Product, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
20.2. Spain Downstream Processing Market, Segmentation By Technique, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
20.3. Spain Downstream Processing Market, Segmentation By Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

21. Eastern Europe Downstream Processing Market

21.1. Eastern Europe Downstream Processing Market Overview
21.2. Eastern Europe Downstream Processing Market, Segmentation By Product, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
21.3. Eastern Europe Downstream Processing Market, Segmentation By Technique, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
21.4. Eastern Europe Downstream Processing Market, Segmentation By Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

22. Russia Downstream Processing Market

22.1. Russia Downstream Processing Market, Segmentation By Product, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
22.2. Russia Downstream Processing Market, Segmentation By Technique, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
22.3. Russia Downstream Processing Market, Segmentation By Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

23. North America Downstream Processing Market

23.1. North America Downstream Processing Market Overview
23.2. North America Downstream Processing Market, Segmentation By Product, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
23.3. North America Downstream Processing Market, Segmentation By Technique, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
23.4. North America Downstream Processing Market, Segmentation By Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

24. USA Downstream Processing Market

24.1. USA Downstream Processing Market Overview
24.2. USA Downstream Processing Market, Segmentation By Product, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
24.3. USA Downstream Processing Market, Segmentation By Technique, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
24.4. USA Downstream Processing Market, Segmentation By Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

25. Canada Downstream Processing Market

25.1. Canada Downstream Processing Market Overview
25.2. Canada Downstream Processing Market, Segmentation By Product, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
25.3. Canada Downstream Processing Market, Segmentation By Technique, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
25.4. Canada Downstream Processing Market, Segmentation By Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

26. South America Downstream Processing Market

26.1. South America Downstream Processing Market Overview
26.2. South America Downstream Processing Market, Segmentation By Product, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
26.3. South America Downstream Processing Market, Segmentation By Technique, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
26.4. South America Downstream Processing Market, Segmentation By Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

27. Brazil Downstream Processing Market

27.1. Brazil Downstream Processing Market, Segmentation By Product, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
27.2. Brazil Downstream Processing Market, Segmentation By Technique, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
27.3. Brazil Downstream Processing Market, Segmentation By Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

28. Middle East Downstream Processing Market

28.1. Middle East Downstream Processing Market Overview
28.2. Middle East Downstream Processing Market, Segmentation By Product, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
28.3. Middle East Downstream Processing Market, Segmentation By Technique, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
28.4. Middle East Downstream Processing Market, Segmentation By Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

29. Africa Downstream Processing Market

29.1. Africa Downstream Processing Market Overview
29.2. Africa Downstream Processing Market, Segmentation By Product, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
29.3. Africa Downstream Processing Market, Segmentation By Technique, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion
29.4. Africa Downstream Processing Market, Segmentation By Application, Historic and Forecast, 2018-2023, 2023-2028F, 2033F, $ Billion

30. Downstream Processing Market Competitive Landscape And Company Profiles

30.1. Downstream Processing Market Competitive Landscape
30.2. Downstream Processing Market Company Profiles
- 30.2.1. Sartorius AG
  - 30.2.1.1. Overview
  - 30.2.1.2. Products and Services
  - 30.2.1.3. Strategy
  - 30.2.1.4. Financial Performance
- 30.2.2. General Electric Company
  - 30.2.2.1. Overview
  - 30.2.2.2. Products and Services
  - 30.2.2.3. Strategy
  - 30.2.2.4. Financial Performance
- 30.2.3. Merck KGaA
  - 30.2.3.1. Overview
  - 30.2.3.2. Products and Services
  - 30.2.3.3. Strategy
  - 30.2.3.4. Financial Performance
- 30.2.4. Thermo Fisher Scientific Inc.
  - 30.2.4.1. Overview
  - 30.2.4.2. Products and Services
  - 30.2.4.3. Strategy
  - 30.2.4.4. Financial Performance
- 30.2.5. Danaher Corporation
  - 30.2.5.1. Overview
  - 30.2.5.2. Products and Services
  - 30.2.5.3. Strategy
  - 30.2.5.4. Financial Performance

31. Global Downstream Processing Market Competitive Benchmarking

32. Global Downstream Processing Market Competitive Dashboard

33. Key Mergers And Acquisitions In The Downstream Processing Market

34. Downstream Processing Market Future Outlook and Potential Analysis

34.1 Downstream Processing Market In 2028 - Countries Offering Most New Opportunities
34.2 Downstream Processing Market In 2028 - Segments Offering Most New Opportunities
34.3 Downstream Processing Market In 2028 - Growth Strategies
- 34.3.1 Market Trend Based Strategies
- 34.3.2 Competitor Strategies

35. Appendix

35.1. Abbreviations
35.2. Currencies
35.3. Historic And Forecast Inflation Rates
35.4. Research Inquiries
35.5. The Business Research Company
35.6. Copyright And Disclaimer