PUBLISHER: The Business Research Company | PRODUCT CODE: 1680815
PUBLISHER: The Business Research Company | PRODUCT CODE: 1680815
Acute lymphocytic leukemia (ALL), also known as acute lymphoblastic leukemia, is a rapidly progressing cancer that originates in the bone marrow, where blood cells are produced. It predominantly affects immature white blood cells called lymphocytes, which play a crucial role in the body's immune system.
The primary therapeutic modalities for acute lymphocytic-lymphoblastic leukemia include chemotherapy, targeted therapy, radiation therapy, and stem cell transplantation. Chemotherapy is a systemic treatment that utilizes drugs to destroy or inhibit the growth of rapidly dividing cells, including cancer cells. The diagnostic procedures for ALL involve various tests such as biopsy and bone marrow aspiration, complete blood count (CBC) and differential, assessment for the presence of the Philadelphia chromosome, spinal tap and cerebrospinal fluid (CSF) analysis, and immunophenotyping or phenotyping by flow cytometry. Additionally, molecular diagnostic techniques such as polymerase chain reaction (PCR) are used. Acute lymphocytic-lymphoblastic leukemia can be diagnosed in various cell types, including the Philadelphia chromosome, precursor B-cell ALL, and T-cell ALL. The administration routes for treatment include oral and parenteral, catering to both pediatric and adult age groups.
The acute lymphocytic-lymphoblastic leukemia therapeutics market research report is one of a series of new reports from The Business Research Company that provides acute lymphocytic-lymphoblastic leukemia therapeutics market statistics, including acute lymphocytic-lymphoblastic leukemia therapeutics industry global market size, regional shares, competitors with an acute lymphocytic-lymphoblastic leukemia therapeutics market share, detailed acute lymphocytic-lymphoblastic leukemia therapeutics market segments, market trends and opportunities, and any further data you may need to thrive in the acute lymphocytic-lymphoblastic leukemia therapeutics industry. This acute lymphocytic-lymphoblastic leukemia therapeutics market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The acute lymphocytic-lymphoblastic leukemia therapeutics market size has grown strongly in recent years. It will grow from $2.85 billion in 2024 to $3.02 billion in 2025 at a compound annual growth rate (CAGR) of 5.9%. The growth in the historic period can be attributed to chemotherapy advancements, biological and targeted therapies, pediatric oncology research, improved supportive care, stem cell transplantation.
The acute lymphocytic-lymphoblastic leukemia therapeutics market size is expected to see strong growth in the next few years. It will grow to $3.74 billion in 2029 at a compound annual growth rate (CAGR) of 5.5%. The growth in the forecast period can be attributed to personalized medicine approaches, expanded access to novel agents, global health initiatives, patient advocacy and awareness, regulatory pathway streamlining. Major trends in the forecast period include supportive care innovation, collaborative research efforts, diagnostic innovations, car-t cell therapies, innovations in biologics.
The increasing prevalence of genetic conditions is anticipated to drive the growth of the acute lymphocytic-lymphoblastic leukemia (ALL) therapeutics market in the future. Genetic conditions are medical issues caused by alterations (mutations) in an individual's DNA or genes. Over time, gene mutations can accumulate in cells, and cells with excessive mutations may cease to function normally, proliferate uncontrollably, and become cancerous. Genetic testing is employed therapeutically to identify specific genetic abnormalities in individuals with acute lymphocytic-lymphoblastic leukemia, which can help guide treatment decisions. For instance, in 2023, the Cystic Fibrosis Foundation, a US-based non-profit organization, reported that the total population with cystic fibrosis who did not undergo lung transplantation increased from 31,171 in 2022 to 31,752 in 2023. Thus, the rising prevalence of genetic conditions is fueling the growth of the acute lymphocytic-lymphoblastic leukemia (ALL) therapeutics market.
The growing demand for bone marrow transplantation is expected to boost the growth of the acute lymphocytic-lymphoblastic leukemia therapeutics market in the future. Bone marrow transplantation is a medical procedure that involves replacing damaged or diseased bone marrow with healthy hematopoietic stem cells. This procedure offers several potential advantages in acute lymphocytic-lymphoblastic leukemia, including higher remission rates, reduced symptoms, eradication of minimal residual disease (MRD), and the possibility of a cure. For example, in June 2023, the Health Resources and Services Administration reported that the number of registered bone marrow donors rose from 9,285,029 in 2021 to 9,475,534 in 2022. Consequently, the increasing demand for bone marrow transplantation is propelling the growth of the acute lymphocytic-lymphoblastic leukemia therapeutics market.
Major companies within the acute lymphocytic-lymphoblastic leukemia (ALL) therapeutics market are developing innovative therapies, such as Tecartus (brexucabtagene autoleucel), by utilizing chimeric antigen receptor (CAR) T-cell therapy and obtaining approvals to better address the needs of their current consumers. CAR T-cell therapy is a form of immunotherapy that employs a patient's own T cells to combat cancer. For example, in July 2024, Janssen Research & Development LLC, a US-based pharmaceutical company, received approval from the US Food and Drug Administration (FDA), a federal agency, for its daratumumab and hyaluronidase-fish in combination with bortezomib, lenalidomide, and dexamethasone for the induction and consolidation of multiple myeloma in patients undergoing autologous stem cell transplantation (ASCT).
In February 2024, BioNTech SE, a biotechnology company based in Germany, partnered with Autolus Ltd. This collaboration enables both companies to access manufacturing and commercial infrastructure as well as technology to advance their autologous CAR-T cell therapy program. Autolus Ltd. is a biotechnology company located in the UK.
Major companies operating in the acute lymphocytic-lymphoblastic leukemia therapeutics market report are Pfizer Inc., F. Hoffmann-La Roche Ltd., AbbVie Inc., Novartis AG, Sanofi S.A., Bristol-Myers Squibb Company, GlaxoSmithKline PLC, Takeda Pharmaceutical Company Limited, Gilead Sciences Inc., Amgen Inc., Baxter International Inc., Astellas Pharma Inc., Eisai Co. Ltd., Jazz Pharmaceuticals Inc., Ono Pharmaceutical Co. Ltd., Genmab A/S, Kite Pharma, ADC Therapeutics, Kiadis Pharma, SymBio Pharmaceuticals Limited, Celyad Oncology SA, Precigen Inc., Leadiant Biosciences Inc., Medexus Pharma Inc., Spectrum Pharmaceuticals Inc., OBI Pharma Inc.
North America was the largest region in the acute lymphocytic-lymphoblastic leukemia (ALL) therapeutics market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the acute lymphocytic-lymphoblastic leukemia therapeutics market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa
The countries covered in the acute lymphocytic-lymphoblastic leukemia therapeutics market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain
The acute lymphocytic-lymphoblastic leukemia (ALL) therapeutics market includes revenues earned by entities by providing services such as laboratory testing, molecular diagnostics, chemotherapy administration, targeted therapy, blood and platelet transfusions, and genetic testing. The market value includes the value of related goods sold by the service provider or included within the service offering. The acute lymphocytic/lymphoblastic leukemia (ALL) therapeutics market also includes sales of Arranon (nelarabine), Asparaginase erwinia chrysanthemi, Asparlas (calaspargase pegol-mknl), Besponsa (inotuzumab ozogamicin), and Blincyto (blinatumomab). Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Acute Lymphocytic-Lymphoblastic Leukemia Therapeutics Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on acute lymphocytic-lymphoblastic leukemia therapeutics market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for acute lymphocytic-lymphoblastic leukemia therapeutics ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The acute lymphocytic-lymphoblastic leukemia therapeutics market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.