PUBLISHER: The Business Research Company | PRODUCT CODE: 1760536
PUBLISHER: The Business Research Company | PRODUCT CODE: 1760536
A gastric antisecretory drug is a medication intended to reduce the production of gastric acid in the stomach. These drugs act by inhibiting specific pathways or receptors that stimulate acid secretion, thereby lowering the acidity of stomach contents. By maintaining a more neutral pH in the gastric environment, these drugs help protect the stomach lining and support digestive health.
The primary drug classes of gastric antisecretory drugs include proton pump inhibitors (PPIs), H2 receptor antagonists, antacids, and prostaglandin analogs. Proton pump inhibitors (PPIs) work by irreversibly inhibiting the enzyme H+/K+-ATPase in the gastric parietal cells, thereby effectively reducing acid production. These medications can be administered via oral, intravenous, or topical routes and are distributed through hospital pharmacies, retail pharmacies, online pharmacies, and other channels. They are used to treat conditions such as gastroesophageal reflux disease (GERD), peptic ulcer disease, Zollinger-Ellison syndrome, and related disorders.
The gastric antisecretory drug market research report is one of a series of new reports from The Business Research Company that provides gastric antisecretory drug market statistics, including gastric antisecretory drug industry global market size, regional shares, competitors with a gastric antisecretory drug market share, detailed gastric antisecretory drug market segments, market trends and opportunities, and any further data you may need to thrive in the gastric antisecretory drug industry. This gastric antisecretory drug market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The gastric antisecretory drug market size has grown strongly in recent years. It will grow from $14.87 billion in 2024 to $15.78 billion in 2025 at a compound annual growth rate (CAGR) of 6.2%. The growth during the historic period can be attributed to factors such as rising stress levels and sedentary lifestyles, an increase in Helicobacter pylori infections, supportive government healthcare policies, the rise of medical tourism, and the expansion of e-commerce and online pharmacy platforms.
The gastric antisecretory drug market size is expected to see strong growth in the next few years. It will grow to $19.97 billion in 2029 at a compound annual growth rate (CAGR) of 6.1%. The projected growth during the forecast period is driven by the increasing prevalence of gastrointestinal disorders, a growing geriatric population, rising awareness about digestive health, expanding healthcare infrastructure, and higher consumption of fast and processed foods. Key trends expected in the forecast period include the widespread use of NSAIDs, greater over-the-counter (OTC) availability of antisecretory drugs, technological advancements in drug delivery systems, increased availability of generic alternatives, and progress in combination therapy development.
The growing prevalence of gastrointestinal disorders is expected to drive the expansion of the gastric antisecretory drug market. Gastrointestinal disorders affect the digestive tract, including the stomach, intestines, and related organs, causing symptoms such as pain, bloating, and changes in bowel movements. The increase in these disorders is largely attributed to unhealthy dietary habits, particularly high intake of processed foods and low fiber consumption, which disrupt the gut microbiota and impair digestion. Gastric antisecretory drugs play a crucial role in preventing damage to the gastrointestinal tract caused by excessive stomach acid. By reducing acid production, these drugs help protect the protective lining of the digestive system from irritation or injury. For example, a report published in May 2025 by ScienceDirect, a US-based bibliographic database, revealed that around 23.5 million gastrointestinal endoscopies were performed in 2022. As such, the rising prevalence of gastrointestinal disorders is expected to significantly drive the growth of the gastric antisecretory drug market.
Major companies in the gastric antisecretory drug market are focusing on developing advanced products, such as new antisecretory compounds, to offer longer-lasting relief. These compounds work by reducing or inhibiting the secretion of gastric acid through targeted actions on specific cellular pathways or receptors. For example, in June 2024, Akums Drugs and Pharmaceuticals, an India-based company, launched Rabeprazole + Levosulpiride SR Capsules, a new formulation designed for gastrointestinal patients. This formulation combines rabeprazole sodium, a potent antisecretory agent that inhibits the H+/K+ ATPase in gastric parietal cells, with levosulpiride, which has central antidopaminergic and antiemetic effects. The capsule delivers 40 mg of enteric-coated rabeprazole and 75 mg of sustained-release levosulpiride, providing targeted and prolonged therapeutic action. Its dual mechanism of action addresses both acid suppression and gastrointestinal motility regulation.
In June 2022, Glenmark Pharmaceuticals Inc., an India-based pharmaceutical company, acquired approved Abbreviated New Drug Applications (ANDAs) from Wockhardt Limited for an undisclosed amount. This acquisition enables Glenmark to strengthen its presence in the U.S. market by adding key products such as Famotidine, Cetirizine Hydrochloride, Lansoprazole, and Olopatadine Hydrochloride to its portfolio. Wockhardt Limited is a manufacturer of gastric antisecretory drugs based in India.
Major players in the gastric antisecretory drug market are Pfizer Inc., Bayer AG, AstraZeneca plc, Takeda Pharmaceutical Company Ltd., Sun Pharmaceutical Industries, Dr. Reddy's Laboratories, Chemo Biological, Spansules Pharmatech Pvt. Ltd., Phoenix Biologicals Pvt. Ltd., Centurion Remedies Private Limited, Solitaire Pharmacia Pvt. Ltd., Shreeji Pharma International, Estrellas Life Sciences Private Limited, 3s Corporation, Actiza Pharmaceutical Private Limited, Lark Laboratories, Cytonova Labs International Private Limited, Luckys Pharma Lab Pvt. Ltd., Lexicare Pharma Pvt. Ltd., Mustcure Healthcare LLP.
North America was the largest region in the gastric antisecretory drug market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in gastric antisecretory drug report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
The countries covered in the gastric antisecretory drug market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The gastric antisecretory drug market consists of sales of mucosal protective agents, digestive enzyme supplements, probiotics for gut health, and controlled-release formulations. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Gastric Antisecretory Drug Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on gastric antisecretory drug market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for gastric antisecretory drug ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The gastric antisecretory drug market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.