PUBLISHER: The Business Research Company | PRODUCT CODE: 1760661
PUBLISHER: The Business Research Company | PRODUCT CODE: 1760661
Oral hypoglycemic agents (OHAs) are medications taken orally to help reduce blood glucose (sugar) levels in individuals with type 2 diabetes mellitus. These medications work through different mechanisms, including increasing insulin secretion, enhancing insulin sensitivity, decreasing glucose absorption from the gut, or reducing glucose production by the liver. OHAs are typically prescribed when lifestyle changes, such as diet and exercise, are not enough to control blood sugar levels.
The primary types of oral hypoglycemic agents include sulfonylureas, metformin, thiazolidinediones, alpha-glucosidase inhibitors, and immunotherapy. Sulfonylureas are a class of oral hypoglycemic agents that stimulate the pancreas to release more insulin by targeting beta cells, which helps lower blood glucose levels in individuals with type 2 diabetes. These drugs are available in various forms, such as oral tablets, oral liquids, extended-release formulations, and combination therapy formulations. The patient groups include individuals with type 2 diabetes mellitus, pre-diabetic patients, obese or overweight individuals, and those with multiple comorbidities. They are distributed through various channels like hospital pharmacies, retail pharmacies, online pharmacies, and nursing homes or long-term care facilities. The main end users are hospitals and clinics.
The oral hypoglycemic agents market research report is one of a series of new reports from The Business Research Company that provides oral hypoglycemic agents market statistics, including the oral hypoglycemic agents industry global market size, regional shares, competitors with the oral hypoglycemic agents market share, detailed oral hypoglycemic agents market segments, market trends, and opportunities, and any further data you may need to thrive in the oral hypoglycemic agents industry. This oral hypoglycemic agents market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.
The oral hypoglycemic agents market size has grown strongly in recent years. It will grow from $57.04 billion in 2024 to $60.15 billion in 2025 at a compound annual growth rate (CAGR) of 5.5%. The growth during the historic period can be attributed to factors such as the increasing prevalence of type 2 diabetes, a rising geriatric population, greater awareness of diabetes management, expanded healthcare access in emerging markets, and a preference for oral therapies over injectable ones.
The oral hypoglycemic agents market size is expected to see strong growth in the next few years. It will grow to $73.69 billion in 2029 at a compound annual growth rate (CAGR) of 5.2%. In the forecast period, growth is expected to be driven by a rising demand for combination therapies, supportive government healthcare policies, increased adoption of telemedicine for diabetes care, greater investment in research and development for diabetes treatments, and a stronger focus on personalized treatment approaches. Key trends in this period include the development of novel oral antidiabetic drugs, the creation of fixed-dose combinations, advancements in drug formulation technologies, efforts to reduce drug side effects, and the integration of digital health tools for glucose monitoring.
The increasing prevalence of type 2 diabetes is expected to drive the growth of the oral hypoglycemic agents market. Type 2 diabetes is a chronic metabolic disorder where the body becomes ineffective in using insulin, resulting in high blood glucose levels. The rise in type 2 diabetes is largely due to more sedentary lifestyles, which reduce physical activity and contribute to obesity and insulin resistance. Oral hypoglycemic agents are used to manage type 2 diabetes by lowering blood glucose through mechanisms such as improving insulin sensitivity, stimulating insulin production, or reducing glucose absorption. According to the International Diabetes Federation (IDF), nearly 589 million adults aged 20-79 are living with diabetes worldwide as of April 2025, and this number is projected to rise to 853 million by 2050. This increasing incidence of type 2 diabetes is expected to drive market growth for oral hypoglycemic agents.
Leading companies in the oral hypoglycemic agents market are concentrating on developing advanced therapeutic options, including dipeptidyl peptidase-4 (DPP-4) inhibitors, to enhance blood sugar control for type 2 diabetes patients. DPP-4 inhibitors are medications that increase incretin hormone levels, stimulating insulin production to reduce blood sugar levels. For example, in June 2022, Gan & Lee Pharmaceuticals Co. Ltd., a China-based pharmaceutical company, received approval for Sitagliptin Phosphate tablets, an oral hypoglycemic medication designed to manage type 2 diabetes effectively. This product works by inhibiting the DPP-4 enzyme, helping regulate blood sugar levels, and marks Gan & Lee Pharmaceuticals' entry into the generic drug market, offering a more affordable option for managing type 2 diabetes.
In July 2024, F. Hoffmann-La Roche Ltd., a Swiss pharmaceutical company, acquired Carmot Therapeutics Inc. for \$2.7 billion. This acquisition allows Roche to strengthen its position in the obesity and diabetes treatment market by expanding its portfolio of incretin-based therapies. Carmot Therapeutics Inc., based in the US, specializes in developing incretin-based treatments for obesity, diabetes, and related metabolic conditions.
Major players in the oral hypoglycemic agents market are Pfizer Inc., Janssen Global Services LLC, Merck Sharp & Dohme Corp., Bayer AG, Bristol-Myers Squibb Company, Sanofi S.A., AstraZeneca plc, Novartis AG, GSK plc, Takeda Pharmaceuticals Limited, Eli Lilly and Company, Boehringer Ingelheim Ltd., Novo Nordisk A/S, Astellas Pharma Inc., Laboratoires Servier, Huadong Medicine Co. Ltd., Tonghua Dongbao Pharmaceutical Co. Ltd., Gan & Lee Pharmaceuticals Co. Ltd., Biocon Limited, Wanbang Biopharmaceuticals Co. Ltd.
North America was the largest region in the oral hypoglycemic agents market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in oral hypoglycemic agents report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
The countries covered in the oral hypoglycemic agents market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The oral hypoglycemic agents market consists of sales of DPP-4 inhibitors, alpha-glucosidase inhibitors, biguanides, and thiazolidinediones (TZDs). Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Oral Hypoglycemic Agents Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on oral hypoglycemic agents market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for oral hypoglycemic agents ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The oral hypoglycemic agents market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.