PUBLISHER: The Business Research Company | PRODUCT CODE: 1760701
PUBLISHER: The Business Research Company | PRODUCT CODE: 1760701
Primary ovarian insufficiency (POI) is a condition in which the ovaries stop functioning properly before the age of 40, leading to reduced estrogen production and irregular or absent menstrual periods. This condition can result in infertility and is often linked to hormonal imbalances, even though some ovarian activity may still be present.
The main treatments for primary ovarian insufficiency include hormone replacement therapy (HRT), calcium and vitamin D supplements, in vitro fertilization (IVF), stem cell therapy, and other options. Hormone replacement therapy (HRT) involves supplementing hormones, typically estrogen and progesterone, to alleviate symptoms caused by hormonal imbalances or deficiencies, particularly during menopause. Diagnostic methods for POI include blood tests, ultrasound imaging, and genetic testing. This condition can affect individuals across different age groups, including those under 20, 20 to 30 years old, 30 to 45 years old, and those over 45. The treatments are used by various end users, such as hospitals, clinics, and specialized fertility centers.
The primary ovarian insufficiency market research report is one of a series of new reports from The Business Research Company that provides primary ovarian insufficiency market statistics, including the primary ovarian insufficiency industry's global market size, regional shares, competitors with the primary ovarian insufficiency market share, detailed primary ovarian insufficiency market segments, market trends and opportunities, and any further data you may need to thrive in the primary ovarian insufficiency market. This primary ovarian insufficiency market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.
The primary ovarian insufficiency market size has grown rapidly in recent years. It will grow from $1.07 billion in 2024 to $1.18 billion in 2025 at a compound annual growth rate (CAGR) of 10.1%. The growth during the historic period can be attributed to factors such as the increasing prevalence of autoimmune disorders, rising stress levels, a higher incidence of genetic mutations, a growing number of women delaying childbirth, and a rising prevalence of endocrine disorders.
The primary ovarian insufficiency market size is expected to see rapid growth in the next few years. It will grow to $1.73 billion in 2029 at a compound annual growth rate (CAGR) of 10.0%. In the forecast period, growth is expected to be driven by the growing use of assisted reproductive technologies, increased adoption of fertility preservation options, a stronger focus on personalized medicine, rising popularity of hormonal therapies, and a greater use of fertility preservation techniques. Key trends during this period include advancements in diagnostic technologies, the integration of genetic testing, innovations in fertility preservation, the development of non-hormonal therapies, and progress in early detection biomarkers.
The increasing prevalence of autoimmune disorders is expected to drive the growth of the primary ovarian insufficiency (POI) market. Autoimmune disorders occur when the immune system mistakenly attacks and damages the body's own healthy cells and tissues. The rise in autoimmune disorders is primarily attributed to genetic predisposition, where individuals inherit certain genes that make them more vulnerable to immune system malfunctions. Primary ovarian insufficiency (POI) can provide insights into autoimmune disorders by showing how hormonal imbalances and immune system dysregulation interact, leading to a heightened risk of autoimmune diseases in affected individuals. For instance, in November 2024, Versorgungsatlas.de, a Germany-based organization, reported that in 2022, out of 73,241,305 insured individuals, 6,304,340 were diagnosed with at least one autoimmune disease, reflecting a prevalence rate of 8.61%. Therefore, the increasing prevalence of autoimmune disorders is contributing to the growth of the primary ovarian insufficiency market.
Leading companies in the primary ovarian insufficiency market are focusing on developing innovative therapies, such as allogenic exosomal therapy, to restore ovarian function and improve fertility outcomes. Allogenic exosomal therapy uses extracellular vesicles, or exosomes, derived from donor stem cells to deliver regenerative signals that promote tissue repair and restore ovarian function in patients with POI. For example, in October 2022, Vitti Labs LLC, a US-based biotechnology company, received approval from the US Food and Drug Administration (FDA) for EV-Pure, a treatment for primary ovarian insufficiency. This therapy leverages the regenerative, immunomodulatory, and anti-inflammatory properties of mesenchymal stromal cell-derived exosomes to restore ovarian function and fertility. It provides an off-the-shelf, cell-free solution that avoids the risks associated with cell-based treatments, such as malignant transformation or immune rejection, while delivering bioactive molecules to promote tissue repair and homeostasis.
In July 2023, EQT Private Capital Asia, a China-based investment company, acquired a 60% stake in Indira IVF Hospital Pvt. Ltd. for \$1.1 billion. This acquisition aims to expand Indira IVF's market leadership in India and Asia, enhance its technological capabilities, and scale operations to take advantage of the rapidly growing fertility services market. Indira IVF Hospital Pvt. Ltd. is a fertility clinic based in India that specializes in the diagnosis and treatment of primary ovarian insufficiency (POI), also known as premature ovarian failure (POF).
Major players in the primary ovarian insufficiency market are Mayo Clinic, Johns Hopkins Medicine, Baptist Health, Ferring Pharmaceuticals A/S, The Kingsley Natural Health Clinic, PreventionGenetics LLC, The Fertility Partnership (TFP) UK, Celmatix Inc., European Society of Human Reproduction and Embryology (ESHRE), Endocrine Society, IVIRMA Global, American Society for Reproductive Medicine (ASRM), TCM Healthcare (UK) Ltd., Bioscience Institute S.p.A., Sparsh Diagnostics Pvt. Ltd., Welling Homeopathy Clinics Pvt. Ltd., Bristol Menopause Clinic, Indira IVF Hospital Private Limited, Lawley Pharmaceuticals Pty. Ltd., OvaScience Inc.
North America was the largest region in the primary ovarian insufficiency market in 2024. The regions covered in primary ovarian insufficiency report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
The countries covered in the primary ovarian insufficiency market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The primary ovarian insufficiency market consists of revenues earned by entities by providing services such as fertility treatments, diagnostic and genetic testing services, osteoporosis management services, and endocrinology consultation services. The market value includes the value of related goods sold by the service provider or included within the service offering. The primary ovarian insufficiency market also consists of sales of products including genetic testing kits, bone health supplements, psychological and supportive care products, testosterone therapy, and antioxidant supplements. Values in this market are 'factory gate' values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Primary Ovarian Insufficiency Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on primary ovarian insufficiency market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for primary ovarian insufficiency ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The primary ovarian insufficiency market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.