PUBLISHER: The Business Research Company | PRODUCT CODE: 1810918
PUBLISHER: The Business Research Company | PRODUCT CODE: 1810918
In vivo contract research organizations are specialized service providers that perform research and testing using live animals to assess the safety, efficacy, and pharmacological impacts of drug candidates or medical devices prior to human clinical trials. These organizations are essential in preclinical development, offering services such as toxicology, pharmacokinetics, and disease modeling with both rodent and non-rodent models.
The primary types of in vivo contract research organizations are rodent-based and non-rodent-based. Rodent-based research involves preclinical testing using rodents like mice or rats as model organisms to evaluate the safety, efficacy, and biological effects of new drugs or treatments before they reach human trials. Services typically include clinical trial support, preclinical testing, and post-market evaluations. These organizations follow various laboratory standards, including good laboratory practice (GLP) toxicology and non-GLP protocols. Their research spans numerous therapeutic areas such as oncology, cardiovascular diseases, infectious diseases, neurological disorders, and more. They serve a diverse group of end users, including pharmaceutical and biotechnology companies, contract research organizations (CROs), academic and research institutions, as well as government and regulatory agencies.
Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.
The sudden escalation of U.S. tariffs and the consequent trade frictions in spring 2025 are severely impacting the healthcare sector, particularly in the supply of critical medical devices, diagnostic equipment, and pharmaceuticals. Hospitals and healthcare providers are facing higher costs for imported surgical instruments, imaging equipment, and consumables such as syringes and catheters, many of which have limited domestic alternatives. These increased costs are straining healthcare budgets, leading some providers to delay equipment upgrades or pass on expenses to patients. Additionally, tariffs on raw materials and components are disrupting the production of essential drugs and devices, causing supply chain bottlenecks. In response, the industry is diversifying sourcing strategies, boosting local manufacturing where possible, and advocating for tariff exemptions on life-saving medical products.
The in vivo contract research organization market research report is one of a series of new reports from The Business Research Company that provides in vivo contract research organization market statistics, including in vivo contract research organization global market size, regional shares, competitors with in vivo contract research organization market share, detailed in vivo contract research organization market segments, market trends and opportunities, and any further data you may need to thrive in the in vivo contract research organization industry. The in vivo contract research organization market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The in vivo contract research organization market size has grown strongly in recent years. It will grow from $4.82 billion in 2024 to $5.23 billion in 2025 at a compound annual growth rate (CAGR) of 8.5%. The growth during the historic period can be attributed to escalating drug development costs, a rising prevalence of chronic diseases, increased investment in pharmaceutical research and development, the expansion of biotechnology startups, and strong demand for innovative therapeutics.
The in vivo contract research organization market size is expected to see strong growth in the next few years. It will grow to $7.19 billion in 2029 at a compound annual growth rate (CAGR) of 8.3%. The growth projected for the forecast period can be attributed to rising demand for precision medicine, the global expansion of contract research organization service networks, the emergence of personalized therapeutics, an increasing need for translational research, and the growing number of orphan drugs. Key trends expected during this period include advanced imaging techniques for in vivo models, automation in data processing and reporting, the integration of omics technologies, cloud-based collaboration platforms, and developments in biologics biosimilars.
The increasing emphasis on personalized medicine is expected to drive growth in the in vivo contract research organization market moving forward. Personalized medicine customizes treatment and prevention strategies based on an individual's genetic profile, lifestyle, and environment to enhance health outcomes. This growing focus is largely due to the improved accessibility and affordability of genomic sequencing technologies, which allow for more precise identification of genetic mutations. As a result, tailored therapies can be developed that improve patient outcomes and minimize trial-and-error in treatment. The rising attention to personalized medicine fuels demand in the in vivo CRO market because customized preclinical studies using specific animal models are required to assess targeted therapies and their effects on unique genetic profiles. For example, according to the Personalized Medicine Coalition (PMC), a US-based nonprofit organization, the FDA approved 16 new personalized treatments in 2023, compared to six in 2022. Personalized medicines have accounted for more than one-third of all new drug approvals by the FDA for the fourth consecutive year. Thus, the growing focus on personalized medicine is propelling the growth of the in vivo contract research organization market.
Key players in the in vivo contract research organization market are concentrating on innovative initiatives such as advanced therapy incubator programs to accelerate the development of next-generation therapeutics and support early-stage clinical research. These incubator programs provide specialized resources, mentorship, and infrastructure to assist early-stage biotechnology companies in advancing therapies such as gene, cell, and RNA-based treatments. For instance, in April 2025, Charles River Laboratories International Inc., a US-based pharmaceutical company, launched its first advanced therapy incubator program cohort. This program is designed to support early-stage biotech firms developing next-generation therapies by offering access to Charles River's scientific expertise, cutting-edge laboratory facilities, and customized in vivo models. Participants can quickly generate proof-of-concept data and validate therapeutic candidates in a real-world preclinical setting, helping to shorten time-to-clinic and increase the likelihood of regulatory approval. By bridging the gap between academic innovation and clinical development, this initiative plays a vital role in advancing advanced therapies.
In September 2024, PharmaLegacy Laboratories Co. Ltd., a China-based preclinical contract research organization specializing in pharmacology, acquired BTS Research for an undisclosed amount. This acquisition aims to enhance PharmaLegacy's preclinical service capabilities and establish a strategic laboratory presence in North America to better support global biopharmaceutical clients. BTS Research Inc. is a US-based biotech company offering both in vitro and in vivo research programs.
Major players in the in vivo contract research organization market are Thermo Fisher Scientific Inc., IQVIA Inc., Labcorp Drug Development Inc., ICON plc, Pharmaceutical Product Development LLC, Eurofins Scientific SE, WuXi AppTec, Syneos Health Inc., Charles River Laboratories International Inc., Parexel International Corporation, Evotec SE, GemPharmatech Co Ltd., BIOQUAL Inc., Crown Bioscience Inc., PsychoGenics Inc., Janvier Labs SAS, Taconic Bioscience Inc., Xentech SAS, Pronexus Analytical AB, Altogen Labs Inc., and AniLocus Inc.
North America was the largest region in the in vivo contract research organization market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in in vivo contract research organization report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
The countries covered in the in vivo contract research organization market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The in vivo contract research organization market includes revenues earned by entities by providing services such as conducting pharmacokinetic studies, toxicology testing, and efficacy studies, and related services such as animal modeling, biomarker analysis, and data interpretation. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values and are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
In Vivo Contract Research Organization Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on in vivo contract research organization market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for in vivo contract research organization ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The in vivo contract research organization market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.