PUBLISHER: The Business Research Company | PRODUCT CODE: 1810968
PUBLISHER: The Business Research Company | PRODUCT CODE: 1810968
An mRNA therapeutics CDMO, or messenger ribonucleic acid therapeutics contract development and manufacturing organization, is a specialized third-party provider that offers comprehensive support for the research, development, and scalable production of mRNA-based therapeutic agents under contractual agreements with pharmaceutical or biotechnology companies. These organizations are vital in accelerating time-to-market, ensuring regulatory compliance, and providing flexible manufacturing capacity for mRNA therapeutic pipelines.
The primary types of services offered by mRNA therapeutics CDMOs include development services, manufacturing services, and laboratory services. Development services encompass end-to-end support for the design, optimization, and scale-up of mRNA-based therapeutics, including synthesis, formulation, analytical development, and process development tailored to the specific needs of each client. These therapeutics are applied to treat indications such as infectious diseases, metabolic and genetic disorders, and cardiovascular and cerebrovascular conditions. Applications include viral vaccines, protein replacement therapies, and cancer immunotherapies, and the end users of these services include pharmaceutical companies, biotechnology firms, academic institutions, and research organizations.
Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.
The sudden escalation of U.S. tariffs and the consequent trade frictions in spring 2025 are severely impacting the pharmaceutical companies contend with tariffs on APIs, glass vials, and lab equipment inputs with few alternative sources. Generic drug makers, operating on razor-thin margins, are especially vulnerable, with some reducing production of low-profit medicines. Biotech firms face delays in clinical trials due to tariff-related shortages of specialized reagents. In response, the industry is expanding API production in India and Europe, increasing inventory stockpiles, and pushing for trade exemptions for essential medicines.
The mRNA therapeutics CDMO market research report is one of a series of new reports from The Business Research Company that provides mRNA therapeutics CDMO market statistics, including mRNA therapeutics CDMO industry global market size, regional shares, competitors with a mRNA therapeutics CDMO market share, detailed mRNA therapeutics CDMO market segments, market trends and opportunities, and any further data you may need to thrive in the mRNA therapeutics CDMO industry. This mRNA therapeutics CDMO market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The mRNA therapeutics CDMO market size has grown rapidly in recent years. It will grow from $4.24 billion in 2024 to $4.74 billion in 2025 at a compound annual growth rate (CAGR) of 12.0%. The growth during the historic period can be attributed to the increasing demand for rapid vaccine development, rising public and private funding for mRNA research, a growing incidence of infectious diseases, expanding pharmaceutical outsourcing practices, and an intensified global focus on pandemic preparedness.
The mRNA therapeutics CDMO market size is expected to see rapid growth in the next few years. It will grow to $7.40 billion in 2029 at a compound annual growth rate (CAGR) of 11.8%. The growth in the forecast period can be attributed to the accelerating focus on personalized medicine, rising demand for rapid response platforms against emerging diseases, increasing healthcare expenditure in developing regions, growing government incentives for domestic manufacturing, and heightened interest in applying mRNA technologies to non-infectious diseases. Major trends during this period include advancements in lipid nanoparticle delivery technologies, increased automation in manufacturing processes, broader adoption of modular and continuous manufacturing platforms, improvements in cold chain logistics infrastructure, and the rising integration of artificial intelligence for process optimization.
The increasing burden of chronic and infectious diseases is expected to drive the growth of the mRNA therapeutics CDMO market in the coming years. Chronic and infectious diseases include long-term health conditions such as diabetes, cardiovascular diseases, and asthma, as well as infections caused by pathogens like viruses, bacteria, and parasites that can be transmitted among individuals. This rise is primarily attributed to aging populations, which are more vulnerable to both chronic illnesses and infections. mRNA therapeutics CDMOs support efforts to combat these conditions by offering comprehensive development and manufacturing services that accelerate the delivery of targeted, personalized mRNA treatments. For example, in April 2024, Allergy UK, a UK-based national charity, reported that more than 21 million people in the UK were affected by allergies, making them the most commonly reported chronic condition in 2022. Projections suggest that by 2026, half of Europe's population will experience at least one allergy. Consequently, the growing burden of chronic and infectious diseases is contributing to the expansion of the mRNA therapeutics CDMO market.
Leading companies in the mRNA therapeutics CDMO market are concentrating on innovative developments such as in situ nanomedicine vaccines to enhance the precision and effectiveness of mRNA-based treatments through targeted immune responses. An in situ nanomedicine vaccine represents a next-generation mRNA therapeutic that facilitates the internal generation of nanomedicines within the patient's body. This enables highly targeted delivery and custom immune activation through engineered transgene expression. For instance, in January 2025, Esphera SynBio Inc., a biotechnology company based in Canada, launched a new initiative backed by the CQDM Quantum Leap program. The project seeks to improve first-generation lipid nanoparticle/mRNA vaccines by introducing proprietary transgene designs that enable in vivo production of immunostimulatory nanomedicines. This strategy enhances antigen targeting and allows for customized immune responses, representing a potential breakthrough in vaccine development.
In September 2024, Agilent Technologies Inc., a US-based medical equipment company, acquired BIOVECTRA for $0.925 billion. The acquisition is intended to strengthen Agilent's CDMO capabilities in emerging therapeutic areas, particularly mRNA-based treatments, by incorporating BIOVECTRA's specialized knowledge in biologics and advanced pharmaceutical manufacturing. BIOVECTRA is a Canada-based contract development and manufacturing organization focused on mRNA therapeutics and related modalities.
Major players in the mRNA therapeutics CDMO market are Sanofi SA, Thermo Fisher Scientific Inc., Boehringer Ingelheim, Danaher Corporation, Merck KGaA, FUJIFILM Holdings Corporation, Evonik Industries AG, BioNTech SE, AGC Biologics GmbH, Eurofins Scientific SA, Samsung Biologics Co. Ltd., Wuxi Biologics, Recipharm AB, EMERGENT BioSolutions Inc., Genscript Biotech, Novo Holdings AS, Ginkgo Bioworks Holdings Inc., Corden Pharma Corp., CureVac SE, TriLink BioTechnologies LLC, Biocina Pty Ltd., Aldevron LLC, Synbio Technologies LLC, etherna manufacturing, Bio-Synthesis Inc., Biomay AG, and RiboPro.
North America was the largest region in the mRNA therapeutics CDMO market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in mRNA therapeutics CDMO report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
The countries covered in the mRNA therapeutics CDMO market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The mRNA therapeutics CDMO market consists of revenues earned by entities by providing services such as supply chain management, cold chain logistics, quality assurance auditing, clinical trial material preparation, batch release testing, serialization, and packaging. The market value includes the value of related goods sold by the service provider or included within the service offering. The mRNA therapeutics CDMO market also includes sales of products such as lipid excipients, nucleotide reagents, capping analogs, custom RNA oligonucleotides, and modified nucleosides. Values in this market are 'factory gate' values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
mRNA Therapeutics CDMO Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on mrna therapeutics cdmo market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for mrna therapeutics cdmo ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The mrna therapeutics cdmo market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.