Ulcerative Colitis Global Market Report 2025

Ulcerative colitis, classified as a chronic inflammatory bowel disease (IBD), is identified as an autoimmune disorder wherein the immune system targets the healthy tissue of the large intestine, leading to inflammation in the superficial layer of the large intestine. Symptoms associated with ulcerative colitis encompass diarrhea, weight loss, abdominal cramping, anemia, and the presence of blood or pus in bowel movements.

The primary categories of drugs used to address ulcerative colitis include anti-inflammatory drugs, anti-TNF biologics, immunosuppressants, calcineurin inhibitors, and others. Anti-inflammatory drugs are substances or medications designed to diminish inflammation (characterized by redness, swelling, and pain) in the body. These drugs are prescribed for various manifestations of the disease, such as ulcerative proctitis, proctosigmoiditis, left-sided colitis, pancolitis or universal colitis, and fulminant colitis. They are available in different molecule types, including biologics and small molecules, which can be administered either orally or through injections. The utilization of these drugs extends across various end-users, including hospital pharmacies, retail pharmacies, drug stores, and other healthcare providers.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The sharp rise in U.S. tariffs and the resulting trade tensions in spring 2025 are having a significant impact on the healthcare sector, especially in the supply of essential medical devices, diagnostic equipment, and pharmaceuticals. Hospitals and healthcare providers are grappling with higher costs for imported surgical tools, imaging systems, and consumables like syringes and catheters, many of which have limited domestic substitutes. These escalating expenses are putting pressure on healthcare budgets, prompting some providers to delay equipment upgrades or pass increased costs on to patients. Furthermore, tariffs on raw materials and components are disrupting the manufacturing of vital drugs and devices, leading to supply chain delays. In response, the industry is adopting diversified sourcing strategies, expanding local production where feasible, and pushing for tariff exemptions on critical medical products.

The ulcerative colitis market research report is one of a series of new reports from The Business Research Company that provides ulcerative colitis market statistics, including ulcerative colitis industry global market size, regional shares, competitors with an ulcerative colitis market share, detailed ulcerative colitis market segments, market trends and opportunities, and any further data you may need to thrive in the ulcerative colitis industry. This ulcerative colitis market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.

The ulcerative colitis market size has grown strongly in recent years. It will grow from $7.39 billion in 2024 to $7.87 billion in 2025 at a compound annual growth rate (CAGR) of 6.4%. The growth in the historic period can be attributed to prevalence of ulcerative colitis, innovations in drug development, biologics and targeted therapies, improved treatment guidelines, patient advocacy and support groups.

The ulcerative colitis market size is expected to see strong growth in the next few years. It will grow to $10.31 billion in 2029 at a compound annual growth rate (CAGR) of 7.0%. The growth in the forecast period can be attributed to advancements in telemedicine, focus on early intervention, biosimilars market growth, research in gut microbiome, emergence of novel therapies. Major trends in the forecast period include patient-centric approaches, global collaborations in research, integration of digital health solutions, innovations in drug delivery, topical and localized therapies.

The forecast of 7.0% growth over the next five years reflects a slight reduction of 0.1% from the previous projection. This reduction is primarily due to the impact of tariffs between the US and other countries. The imposition of tariffs may disrupt U.S. medical supply chains by increasing costs for biologic therapies imported from South Korea and Germany, potentially leading to higher infusion costs and delayed remission induction. The effect will also be felt more widely due to reciprocal tariffs and the negative effect on the global economy and trade due to increased trade tensions and restrictions.

The anticipated growth in the ulcerative colitis market is expected to be driven by the increasing expenditure on healthcare. Healthcare expenditure encompasses all spending related to health services, family planning, nutrition activities, and emergency assistance, excluding costs for drinking water and sanitation. Elevated healthcare spending can benefit individuals affected by ulcerative colitis by enhancing access to medical care and therapies. Given the significant hospitalization costs associated with ulcerative colitis, higher healthcare expenditures can potentially reduce mortality rates and overall healthcare expenses. As of March 2022, the Centers for Medicare & Medicaid Services, a department of the US-based Department of Health and Human Services, projected an annual average increase of 5.1% in national health spending from 2021 to 2030, reaching an estimated $6.8 trillion by 2030. Over the same period, Medicare expenditures are expected to grow at a 7.2% annual rate, while Medicaid spending is forecasted to increase at a 5.6% annual rate. Consequently, the upward trajectory in healthcare expenditures is a key driver of the ulcerative colitis market's growth.

The rising prevalence and incidence of ulcerative colitis are anticipated to contribute to the expansion of the ulcerative colitis market in the near future. Ulcerative colitis, a chronic inflammatory bowel disease primarily affecting the colon and rectum, manifests with ulcers and inflammation in the lining of the large intestine, leading to various symptoms and complications. The increasing incidence and prevalence of ulcerative colitis serve as catalysts, fostering innovation, expansion, and a focus on improving patient outcomes. For example, as of January 2022, Crohn's & Colitis Australia, a non-profit organization based in Australia, projects that the country will have between 100,000 and 160,000 patients with Crohn's disease and ulcerative colitis by 2022. Hence, the growing prevalence and incidence of ulcerative colitis are significant drivers of the ulcerative colitis market.

Technological advancements represent a prominent trend gaining traction in the ulcerative colitis market, with companies in the field embracing new technologies to maintain their market positions. An example of this is seen in March 2023, when Clario ERT Inc., a US-based healthcare research and technology firm, partnered with GI Reviewers LLC and RSIP Vision, a software company based in Israel, to introduce a groundbreaking AI technology-based rating system. This system aims to enhance the efficiency and consistency of scoring for inflammatory bowel diseases (IBD), including ulcerative colitis (UC) and Crohn's disease. The innovative AI technology is designed to improve the repeatability of colonoscopy video scoring, streamline workflow by reducing the time required for human expert readers to score, and ultimately enhance recruitment while lowering clinical trial expenses. The algorithm's performance, measured by the Kappa metric technology, was demonstrated to be equivalent to that of human reviewers. The algorithm underwent training on hundreds of films from various sites and devices, evaluating over 100,000 photos, all assessed by an expert gastroenterologist.

Major companies in the ulcerative colitis market are adopting a strategic partnership approach, collaborating to jointly develop and market pharmaceuticals that are currently in the developmental phase. Strategic partnerships involve companies leveraging each other's strengths and resources for mutual benefits and success. For example, in October 2023, Sanofi S.A., a France-based healthcare and pharmaceutical company, announced a partnership with Teva Pharmaceuticals to collaborate on the development and marketing of the asset TEV'574. This asset is presently undergoing Phase 2b clinical studies for the treatment of Crohn's disease and ulcerative colitis, two forms of inflammatory bowel disease. Under this collaboration agreement, Teva will receive an upfront payment of €469 million ($500 million) and up to €940 million ($1 billion) in milestones related to development and commercialization. Sanofi will lead the development of the Phase 3 program, and both companies will equally share worldwide development costs and net earnings and losses in key markets. Sanofi will oversee product commercialization in North America, Japan, other Asian regions, and globally, while Teva will take charge in Europe, Israel, and several other countries. Teva Pharmaceuticals is a US-based subsidiary of Teva Pharmaceutical Industries Ltd., an Israeli pharmaceutical company.

In March 2022, Pfizer Inc., a US-based biopharmaceutical company, completed the acquisition of Arena Pharmaceuticals Inc. for approximately $6.7 billion. This strategic acquisition aims to expand Pfizer's existing inflammation and immunology pipeline portfolio of drugs into its inflammation and immunology therapeutic area, contributing to the goal of generating breakthroughs to improve the lives of individuals dealing with immuno-inflammatory disorders. Arena Pharmaceuticals Inc., a US-based biopharmaceutical company, is the developer of Etrasimod, a highly selective, once-daily oral sphingosine 1-phosphate (S1P) receptor modulator used in the treatment of ulcerative colitis, Crohn's disease, and other related conditions.

Major companies operating in the ulcerative colitis market include AbbVie Inc., AstraZeneca plc, Bausch Health Companies Inc., Eli Lilly and Co., Johnson & Johnson, Index Pharmaceuticals Holdings AB, GlaxoSmithKline plc, Merck & Co. Inc., Novartis AG, Pfizer Inc., Sanofi S.A., Allergan plc, Bayer AG, BioLineRx Ltd., Celgene Corporation, Bristol Myers Squib Company, Takeda Pharmaceutical Company Limited, Genentech Inc., UCB S.A., Protagonist Therapeutics, Shire plc, Prometheus Laboratories Inc., Cosmo Pharmaceuticals, Dr. Falk Pharma GmbH, Tillotts Pharma AG, Ferring Pharmaceuticals Inc., Salix Pharmaceuticals Inc.

North America was the largest region in the ulcerative colitis market in 2024. The regions covered in the ulcerative colitis market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

The countries covered in the ulcerative colitis market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain

The ulcerative colitis market consists of sales of aminosalicylates and corticosteroids. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Ulcerative Colitis Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on ulcerative colitis market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

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Where is the largest and fastest growing market for ulcerative colitis ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The ulcerative colitis market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

• The market characteristics section of the report defines and explains the market.
• The market size section gives the market size ($b) covering both the historic growth of the market, and forecasting its development.
• The forecasts are made after considering the major factors currently impacting the market. These include:

The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.

• Market segmentations break down the market into sub markets.
• The regional and country breakdowns section gives an analysis of the market in each geography and the size of the market by geography and compares their historic and forecast growth.
• The competitive landscape chapter gives a description of the competitive nature of the market, market shares, and a description of the leading companies. Key financial deals which have shaped the market in recent years are identified.
• The trends and strategies section analyses the shape of the market as it emerges from the crisis and suggests how companies can grow as the market recovers.

Scope

• Markets Covered:1) By Drug Type: Anti-Inflammatory Drugs; Anti-TNF Biologics; Immunosuppressant; Calcineurin Inhibitors; Other Drug Types
• 2) By Disease Type: Ulcerative Proctitis; Proctosigmoiditis; Left-sided Colitis; Pancolitis or Universal Colitis; Fulminant Colitis
• 3) By Molecule Type: Biologics; Small Molecules
• 4) By Route of Administration: Oral; Injectables
• 5) By End-User: Hospital Pharmacies; Retail Pharmacies; Drug Store; Other End-User
• Subsegments:
• 1) By Anti-Inflammatory Drugs: Aminosalicylates; Corticosteroids
• 2) By Anti-TNF Biologics: Infliximab; Adalimumab; Golimumab
• 3) By Immunosuppressant: Azathioprine; Mercaptopurine
• 4) By Calcineurin Inhibitors: Tacrolimus; Cyclosporine
• 5) By Other Drug Types: JAK Inhibitors; Monoclonal Antibodies; Other Novel Therapies
• Companies Mentioned: AbbVie Inc.; AstraZeneca plc; Bausch Health Companies Inc.; Eli Lilly and Co.; Johnson & Johnson; Index Pharmaceuticals Holdings AB; GlaxoSmithKline plc; Merck & Co. Inc.; Novartis AG; Pfizer Inc.; Sanofi S.A.; Allergan plc; Bayer AG; BioLineRx Ltd.; Celgene Corporation; Bristol Myers Squib Company; Takeda Pharmaceutical Company Limited; Genentech Inc.; UCB S.A.; Protagonist Therapeutics; Shire plc; Prometheus Laboratories Inc.; Cosmo Pharmaceuticals; Dr. Falk Pharma GmbH; Tillotts Pharma AG; Ferring Pharmaceuticals Inc.; Salix Pharmaceuticals Inc.
• Countries: Australia; Brazil; China; France; Germany; India; Indonesia; Japan; Russia; South Korea; UK; USA; Canada; Italy; Spain.
• Regions: Asia-Pacific; Western Europe; Eastern Europe; North America; South America; Middle East; Africa
• Time Series: Five years historic and ten years forecast.
• Data: Ratios of market size and growth to related markets, GDP proportions, expenditure per capita,
• Data Segmentations: country and regional historic and forecast data, market share of competitors, market segments.
• Sourcing and Referencing: Data and analysis throughout the report is sourced using end notes.
• Delivery Format: PDF, Word and Excel Data Dashboard.