PUBLISHER: The Business Research Company | PRODUCT CODE: 1825976
PUBLISHER: The Business Research Company | PRODUCT CODE: 1825976
Advanced liver cancer, or hepatocellular carcinoma (HCC) in its later stages, refers to liver cancer that has either spread beyond the liver or grown large enough to significantly impair liver function. At this stage, the cancer may have invaded nearby blood vessels, lymph nodes, or other distant organs, complicating treatment. Common symptoms include jaundice, abdominal pain, weight loss, and fatigue.
Key diagnostic methods for advanced liver cancer include imaging tests, biopsies, genomic tests, and others. Imaging tests play a vital role in diagnosing, staging, and monitoring hepatocellular carcinoma (HCC) by offering detailed images of the liver and surrounding organs. These tests encompass a variety of technologies such as fluorescent in situ hybridization, next-generation sequencing, fluoroimmunoassay, comparative genomic hybridization, immunohistochemistry, and more. They are distributed through different channels, including direct tenders, retail sales, and others. These tests are used in several areas, including screening, diagnostics, prognostics, and research, and are employed by various end users, such as hospitals, cancer research centers, academic institutions, diagnostic centers, and ambulatory surgical centers.
Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.
The sharp rise in U.S. tariffs and the resulting trade tensions in spring 2025 are having a significant impact on the healthcare sector, especially in the supply of essential medical devices, diagnostic equipment, and pharmaceuticals. Hospitals and healthcare providers are grappling with higher costs for imported surgical tools, imaging systems, and consumables like syringes and catheters, many of which have limited domestic substitutes. These escalating expenses are putting pressure on healthcare budgets, prompting some providers to delay equipment upgrades or pass increased costs on to patients. Furthermore, tariffs on raw materials and components are disrupting the manufacturing of vital drugs and devices, leading to supply chain delays. In response, the industry is adopting diversified sourcing strategies, expanding local production where feasible, and pushing for tariff exemptions on critical medical products.
The advanced liver cancer market research report is one of a series of new reports from The Business Research Company that provides advanced liver cancer market statistics including the advanced liver cancer industry global market size regional shares competitors with the advanced liver cancer market share detailed advanced liver cancer market segments market trends and opportunities and any further data you may need to thrive in the advanced liver cancer industry. This advanced liver cancer market research report delivers a complete perspective of everything you need with an in-depth analysis of the current and future scenarios of the industry.
The advanced liver cancer market size has grown rapidly in recent years. It will grow from $1.89 billion in 2024 to $2.16 billion in 2025 at a compound annual growth rate (CAGR) of 14.5%. The growth in the historic period can be attributed to increasing awareness towards liver cancer, increasing patient pool, growing demand for targeted therapies, expanding healthcare infrastructure, and growing demand for minimally invasive treatments.
The advanced liver cancer market size is expected to see rapid growth in the next few years. It will grow to $3.74 billion in 2029 at a compound annual growth rate (CAGR) of 14.7%. The growth in the forecast period can be attributed to the growing incidence of liver cancer, incremental healthcare spending, increasing prevalence of genetic conditions, increasing adoption of precision medicine, and increasing adoption of screening and diagnostic tests. Major trends in the forecast period include the integration of artificial intelligence in treatment, the development of innovative drugs and treatment, expanding research and development activities, the development in targeted therapeutics, and growing demand for personalized medicine.
The forecast of 14.7% growth over the next five years reflects a slight reduction of 0.2% from the previous projection. This reduction is primarily due to the impact of tariffs between the US and other countries. Tariff barriers are expected to hamper the U.S. market by increasing the cost of transarterial chemoembolization (TACE) microspheres and tyrosine kinase inhibitors sourced from France and South Korea, thereby reducing treatment efficacy and elevating hepatology department expenses. The effect will also be felt more widely due to reciprocal tariffs and the negative effect on the global economy and trade due to increased trade tensions and restrictions.
The increasing prevalence of chronic hepatitis infections is expected to drive the growth of the advanced liver cancer market in the future. Chronic hepatitis infections are persistent viral infections lasting over six months, which can cause liver damage, cirrhosis, or even liver cancer. The rise in these infections is influenced by factors such as insufficient screening and vaccination programs, as well as delayed treatment access. Hepatitis B (HBV) and hepatitis C (HCV) chronic infections are primary causes of liver cirrhosis and hepatocellular carcinoma (HCC), the most common type of liver cancer. Over time, these viral infections lead to liver inflammation, damage, and ultimately cancer. As the incidence of these infections remains high, more individuals are at risk of developing advanced liver cancer. For example, in April 2024, the World Health Organization (WHO) reported that, in 2022, chronic hepatitis B affected 254 million people globally, with 1.2 million new cases diagnosed each year. As a result, the growing prevalence of long-term hepatitis infections is contributing to the expansion of the advanced liver cancer market.
Leading companies in the advanced liver cancer market are focusing on the development of innovative treatments, such as human monoclonal antibodies, to enhance treatment effectiveness and reduce side effects, ultimately improving patient outcomes. A human monoclonal antibody is a laboratory-made molecule that mimics the immune system's ability to fight harmful pathogens or cancer cells. It works by targeting specific antigens on the surface of these harmful entities, triggering an immune response. For example, in October 2022, AstraZeneca, a pharmaceutical company based in the US, announced that the U.S. Food and Drug Administration (FDA) had approved Imjudo (tremelimumab) in combination with Imfinzi (durvalumab) for treating adult patients with unresectable hepatocellular carcinoma (HCC), the most common type of liver cancer. This approval followed the results of the HIMALAYA Phase III trial, which showed that the combination therapy reduced the risk of death by 22% compared to sorafenib. Additionally, about 31% of patients treated with the combination were alive after three years, compared to 20% of those treated with sorafenib. The treatment regimen, known as STRIDE, consists of a single dose of Imjudo followed by regular doses of Imfinzi every four weeks, offering a new therapeutic option for patients with limited treatment alternatives.
In March 2023, the University of Southern California (USC), a private research university based in the US, partnered with Auransa Inc. to further clinical trials for a new targeted treatment for liver cancer. This collaboration combines their expertise to enhance treatment effectiveness for liver cancer and other solid tumors. Auransa Inc., a pharmaceutical company based in the US, specializes in treating advanced liver cancers.
Major players in the advanced liver cancer market are Pfizer Inc., F. Hoffmann-La Roche AG, Merck Co. Inc., Bayer AG, Sanofi S.A., Bristol-Myers Squibb Company, AstraZeneca plc, Novartis AG, Eli Lilly and Company, Stryker Corporation, Agilent Technologies Inc., Eisai Co. Ltd., Jiangsu Hengrui Pharmaceutical Co. Ltd, Exelixis Inc., Sirtex Medical Limited, Eureka Therapeutics, Abbisko Therapeutics Co. Ltd., Binhui Biopharmaceutical Co. Ltd., Tempest Therapeutics Inc., Auransa Inc., Mina Alpha Limited, Jennerex Inc.
North America was the largest region in the advanced liver cancer market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in advanced liver cancer report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
The countries covered in the advanced liver cancer market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The advanced liver cancer market consists of revenues earned by entities that provide services such as diagnostic services, surgical services, patient support and management. The market value includes the value of related goods sold by the service provider or included within the service offering. The advanced liver cancer market also includes sales of biopsy tools, computed tomography (CT) scans, liver function tests kit, and supportive care products. Values in this market are 'factory gate' values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Advanced Liver Cancer Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on advanced liver cancer market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for advanced liver cancer ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The advanced liver cancer market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.