PUBLISHER: The Business Research Company | PRODUCT CODE: 1826950
PUBLISHER: The Business Research Company | PRODUCT CODE: 1826950
Metastatic urothelial carcinoma is an advanced form of bladder cancer where the cancer has spread beyond the urothelium to distant organs or lymph nodes. Treatment for metastatic urothelial carcinoma involves advanced diagnostic technologies, targeted therapies, and immunotherapies to manage and treat cancer that has spread beyond the bladder or urinary tract.
The primary treatment options for metastatic urothelial carcinoma include chemotherapy, targeted therapy, immunotherapy, radiation therapy, and intravesical therapy. Chemotherapy uses drugs to kill cancer cells or inhibit their growth. Diagnostic methods for detecting this cancer include urine lab tests, cystoscopy, intravenous pyelogram (IVP), and biopsy. Treatments can include medications, lifestyle changes, and other therapies, with administration routes such as oral, parenteral, and others. These treatments are utilized in various settings, including hospitals, oncology clinics, research institutes, and other healthcare facilities.
Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.
The sharp rise in U.S. tariffs and the resulting trade tensions in spring 2025 are having a significant impact on the healthcare sector, especially in the supply of essential medical devices, diagnostic equipment, and pharmaceuticals. Hospitals and healthcare providers are grappling with higher costs for imported surgical tools, imaging systems, and consumables like syringes and catheters, many of which have limited domestic substitutes. These escalating expenses are putting pressure on healthcare budgets, prompting some providers to delay equipment upgrades or pass increased costs on to patients. Furthermore, tariffs on raw materials and components are disrupting the manufacturing of vital drugs and devices, leading to supply chain delays. In response, the industry is adopting diversified sourcing strategies, expanding local production where feasible, and pushing for tariff exemptions on critical medical products.
The metastatic urothelial carcinoma market research report is one of a series of new reports from The Business Research Company that provides metastatic urothelial carcinoma market statistics, including metastatic urothelial carcinoma industry global market size, regional shares, competitors with a metastatic urothelial carcinoma market share, detailed metastatic urothelial carcinoma market segments, market trends and opportunities, and any further data you may need to thrive in the metastatic urothelial carcinoma industry. This metastatic urothelial carcinoma market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The metastatic urothelial carcinoma market size has grown rapidly in recent years. It will grow from $1.18 billion in 2024 to $1.42 billion in 2025 at a compound annual growth rate (CAGR) of 19.9%. The growth in the historic period can be attributed to favorable regulatory environment, rising incidence of smoking-related cancers, emergence of combination therapies, supportive government policies and heightened awareness and early diagnosis.
The metastatic urothelial carcinoma market size is expected to see rapid growth in the next few years. It will grow to $2.91 billion in 2029 at a compound annual growth rate (CAGR) of 19.6%. The growth in the forecast period can be attributed to increased patient advocacy, government programs supporting cancer care, growth of the biopharmaceutical industry, surging application of chemotherapy and rapid urbanization and changes in lifestyle. Major trends in the forecast period include advancements in immunotherapy, integration of artificial intelligence, collaborations between pharma and biotech companies, telemedicine advancements, aba=nd development of next-generation drugs.
The forecast of 19.6% growth over the next five years reflects a modest reduction of 0.2% from the previous estimate for this market. This reduction is primarily due to the impact of tariffs between the US and other countries. Tariff escalations are likely to burden U.S. patients by driving up the cost of antibody-drug conjugates and Fibroblast Growth Factor Receptor(FGFR)-targeted therapies sourced from Japan and Belgium, exacerbating out-of-pocket expenses for late-stage bladder cancer management. The effect will also be felt more widely due to reciprocal tariffs and the negative effect on the global economy and trade due to increased trade tensions and restrictions.
The increasing incidence of bladder cancer is expected to drive the growth of the metastatic urothelial carcinoma market. Bladder cancer is a condition where malignant cells form in the bladder tissues, typically starting in the urothelial cells lining the bladder. The rise in bladder cancer cases is attributed to factors such as smoking, chemical exposure, chronic bladder inflammation, and improvements in detection methods. As metastatic urothelial carcinoma represents an advanced and aggressive stage of bladder cancer, it highlights the critical need for early detection, better treatment options, and increased research, ultimately fostering innovations in the management of bladder cancer and improving patient outcomes. For example, according to a February 2023 report from Cancer Research UK, the number of new bladder cancer cases in the UK is projected to rise from about 9,800 annually between 2023 and 2025 to around 10,700 cases per year by 2038-2040. This growing prevalence of bladder cancer is driving the expansion of the metastatic urothelial carcinoma market.
Regulatory approvals for new treatments are also contributing to the market's growth. Major companies in the metastatic urothelial carcinoma space are obtaining regulatory approvals for drugs, expanding their market reach and reinforcing their position in treating adult patients with locally advanced or metastatic urothelial carcinoma (la/mUC). Regulatory approvals involve the formal authorization granted by governmental bodies for drugs or treatments to be marketed to the public. For example, in April 2023, Merck & Co. Inc., a US-based pharmaceutical company, received FDA approval for KEYTRUDA (pembrolizumab) as a first-line treatment for certain patients with locally advanced or metastatic urothelial cancer. This approval marks a significant step in urothelial cancer treatment, as the combination of KEYTRUDA (pembrolizumab) and enfortumab vedotin became the first anti-PD-1 therapy approved in the U.S. in combination with an antibody-drug conjugate for patients with locally advanced or metastatic urothelial cancer. The combination therapy demonstrated a statistically significant improvement in overall survival (OS) and progression-free survival (PFS) when compared to traditional platinum-based chemotherapy, offering a new option for patients with limited treatment alternatives.
In December 2023, Pfizer Inc., a US-based pharmaceutical company, acquired Seagen Inc. for an undisclosed amount. This acquisition enables Pfizer to enhance its oncology portfolio by integrating Seagen's innovative antibody-drug conjugate (ADC) technology and expanding its ability to develop targeted cancer therapies. This move strengthens Pfizer's leadership in cancer treatment and broadens its oncology product pipeline. Seagen, a US-based biotechnology company, specializes in therapies for metastatic urothelial carcinoma.
Major players in the metastatic urothelial carcinoma market are Pfizer Inc., Johnson & Johnson Services Inc., F. Hoffmann-La Roche Ltd., Merck & Co., Inc., AbbVie Inc., Bayer AG, Bayer Aktiengesellschaft, Bristol-Myers Squibb Company, AstraZeneca PLC, Eli Lilly and Company, Gilead Sciences Inc., Merck KGaA, Astellas Pharma Inc., Genentech Inc., Genentech Inc., Exelixis Inc., EMD Serono, Zymeworks Inc., Mirati Therapeutics Inc., UroGen Pharma Ltd.
North America was the largest region in the metastatic urothelial carcinoma market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in metastatic urothelial carcinoma report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
The countries covered in the metastatic urothelial carcinoma market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The metastatic urothelial carcinoma market consists of revenues earned by entities by providing services such as sales of surgical treatment, combination therapy and supportive care. The market value includes the value of related goods sold by the service provider or included within the service offering. The metastatic urothelial carcinoma market also includes sales of chemotherapy agents, immunotherapy drugs, tyrosine kinase inhibitors, adjuvant treatments, and targeted therapies. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Metastatic Urothelial Carcinoma Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on metastatic urothelial carcinoma market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for metastatic urothelial carcinoma ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The metastatic urothelial carcinoma market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.