PUBLISHER: The Business Research Company | PRODUCT CODE: 1826999
PUBLISHER: The Business Research Company | PRODUCT CODE: 1826999
Tay-Sachs disease treatment encompasses therapeutic approaches aimed at managing or potentially curing this rare genetic disorder caused by a deficiency of the enzyme hexosaminidase A (Hex-A). Current treatment efforts include experimental gene therapy, substrate reduction therapy, and supportive care to alleviate symptoms and improve the quality of life for affected individuals.
The primary treatment options for Tay-Sachs disease include medication, respiratory care, and physical therapy. Medication involves prescribed drugs designed to relieve symptoms, slow disease progression, and enhance patient comfort by addressing pain, seizures, muscle stiffness, and related complications. These treatments are administered through various modes, including injectable, oral, and other methods, and are utilized in hospitals, homecare settings, and specialty clinics.
Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.
The sharp rise in U.S. tariffs and the resulting trade tensions in spring 2025 are having a significant impact on the healthcare sector, especially in the supply of essential medical devices, diagnostic equipment, and pharmaceuticals. Hospitals and healthcare providers are grappling with higher costs for imported surgical tools, imaging systems, and consumables like syringes and catheters, many of which have limited domestic substitutes. These escalating expenses are putting pressure on healthcare budgets, prompting some providers to delay equipment upgrades or pass increased costs on to patients. Furthermore, tariffs on raw materials and components are disrupting the manufacturing of vital drugs and devices, leading to supply chain delays. In response, the industry is adopting diversified sourcing strategies, expanding local production where feasible, and pushing for tariff exemptions on critical medical products.
The tay-sachs disease treatment market research report is one of a series of new reports from The Business Research Company that provides tay-sachs disease treatment market statistics, including the tay-sachs disease treatment industry's global market size, regional shares, competitors with a tay-sachs disease treatment market share, detailed tay-sachs disease treatment market segments, market trends and opportunities, and any further data you may need to thrive in the tay-sachs disease treatment industry. This tay-sachs disease treatment market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.
The tay-sachs disease treatment market size has grown strongly in recent years. It will grow from $2.28 billion in 2024 to $2.45 billion in 2025 at a compound annual growth rate (CAGR) of 7.2%. The growth in the historic period can be attributed to increase in genetic screening, increase focus on rare diseases, rise in demand for quality healthcare, rise in cases of tay-sachs disease, and rise in chronic condition cases.
The tay-sachs disease treatment market size is expected to see strong growth in the next few years. It will grow to $3.23 billion in 2029 at a compound annual growth rate (CAGR) of 7.2%. The growth in the forecast period can be attributed to rising prevalence of lysosomal storage disorders, growing awareness initiatives, expansion of genetic testing services, growing demand for symptomatic treatments, and rising prevalence of genetic diseases. Major trends in the forecast period include advancements in gene therapy, cost-effective next-generation sequencing, automated cloning platforms, developments in drug delivery systems, integration of AI and machine learning, and adoption of telemedicine solutions.
The forecast of 7.2% growth over the next five years reflects a slight reduction of 0.1% from the previous projection. This reduction is primarily due to the impact of tariffs between the US and other countries. The imposition of tariffs may disrupt rare disease management by increasing costs for enzyme replacement therapies and genetic testing kits imported from France and the UK, potentially compromising early intervention and increasing pediatric neurology expenses. The effect will also be felt more widely due to reciprocal tariffs and the negative effect on the global economy and trade due to increased trade tensions and restrictions.
The increasing prevalence of genetic diseases is expected to drive advancements in the Tay-Sachs disease treatment market. Genetic diseases result from abnormalities in an individual's DNA, either inherited or caused by spontaneous mutations. The rise in these conditions is attributed to improved diagnostics, heightened awareness, environmental factors, and higher mutation rates associated with delayed parenthood and lifestyle changes. The growing occurrence of genetic diseases underscores the need for advancements in Tay-Sachs disease treatment, fueling research in gene therapy, enzyme replacement, and early diagnostics. For example, in February 2022, Genomics England, a UK-based government organization, reported that over 7,000 recognized rare diseases affect approximately 1 in 17 people (3.5 million) in the UK. Consequently, the rising prevalence of genetic diseases is expected to drive the Tay-Sachs disease treatment market forward.
Leading companies in the Tay-Sachs disease treatment market are focusing on innovative therapies, including clinical trials, to explore potential treatments such as gene therapy, enzyme replacement, and small-molecule drugs for improved patient outcomes. Clinical trials are research studies that assess the safety, effectiveness, and potential side effects of medical treatments, drugs, or procedures in humans. For instance, in July 2024, IntraBio Inc., a US-based biopharmaceutical company, announced that it had received US Food and Drug Administration (FDA) approval for its Investigational New Drug (IND) Application to conduct a clinical trial (IB1001-202) for IB1001, targeting GM2 Gangliosidosis (Tay-Sachs and Sandhoff Disease). The trial is being conducted in the U.S., UK, Germany, and Spain to address these fatal neurodegenerative disorders, which currently have no approved treatments. IntraBio's chairman emphasized the urgent need to develop effective therapies for these debilitating conditions.
In June 2023, New Hope Research Foundation Inc., a US-based non-profit research organization, partnered with Forge Biologics Inc. to advance its innovative gene therapy, NHR01, into Phase I/II clinical trials for patients with Tay-Sachs disease and GM2 gangliosidosis. Forge Biologics, a US-based biotechnology company, specializes in gene therapy contract manufacturing and clinical-stage therapeutics.
Major players in the tay-sachs disease treatment market are Pfizer Inc., Sanofi S.A., Novartis AG, Takeda Pharmaceutical Company Limited, Regeneron Pharmaceuticals Inc., Biogen Inc., Vertex Pharmaceuticals Incorporated, BioMarin Pharmaceutical Inc., Sarepta Therapeutics Inc., Ultragenyx Pharmaceutical Inc., Amicus Therapeutics Inc., Spark Therapeutics Inc., Rocket Pharmaceuticals Inc., RegenxBio Inc., Forge Biologics Inc., Passage Bio Inc., Protalix BioTherapeutics Inc., Orchard Therapeutics plc, Affinia Therapeutics Inc., IntraBio Inc., and Taysha Gene Therapies Inc.
North America was the largest region in the tay-sachs disease treatment market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in tay-sachs disease treatment report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
The countries covered in the tay-sachs disease treatment market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The tay-sachs disease treatment market consists of revenues earned by providing services such as respiratory care, physical therapy, genetic counseling, and home care services. The market value includes the value of related goods sold by the service provider or included within the service offering. The tay-sachs disease treatment market includes sales of anticonvulsants, gene therapy products, supportive care products, and diagnostic tools. Values in this market are 'factory gate' values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Tay-Sachs Disease Treatment Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on tay-sachs disease treatment market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for tay-sachs disease treatment ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The tay-sachs disease treatment market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.