PUBLISHER: The Business Research Company | PRODUCT CODE: 1855912
 
				PUBLISHER: The Business Research Company | PRODUCT CODE: 1855912
A library preparation (prep) system is a laboratory platform or workflow designed to process nucleic acids for sequencing or other genomic applications. It includes steps such as fragmentation, adapter ligation, amplification, and purification to convert raw biological samples into sequence-ready libraries. The system ensures high-quality, consistent, and efficient sample preparation, enabling accurate and reproducible downstream sequencing and analysis.
The primary product types of library preparation (prep) systems are manual and automated library prep systems. Manual library prep systems are hand-operated kits and protocols used to prepare DNA or RNA samples for sequencing, requiring direct human handling rather than automation. These systems support technologies such as next-generation sequencing (NGS), Sanger sequencing, and microarrays, and are applied across workflow stages including sample preparation, library preparation, quality control, and data analysis. Key applications include whole genome sequencing, targeted sequencing, RNA sequencing, exome sequencing, and metagenomics, serving academic and research institutes, pharmaceutical and biotechnology companies, clinical laboratories, and diagnostic laboratories.
Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.
The fast surge in U.S. tariffs and the trade tensions that followed in spring 2025 are heavily affecting the medical equipment sector, particularly for imported imaging machine components, surgical-grade stainless steel, and plastic disposables. Hospitals and clinics resist price hikes, pressuring manufacturers' margins. Regulatory hurdles compound the problem, as tariff-related supplier changes often require re-certification of devices, delaying time-to-market. Companies are mitigating risks by dual-sourcing critical parts, expanding domestic production of commoditized items, and accelerating R&D in cost-efficient materials.
The library preparation (prep) system market research report is one of a series of new reports from The Business Research Company that provides library preparation (prep) system market statistics, including the library preparation (prep) system industry global market size, regional shares, competitors with the library preparation (prep) system market share, detailed library preparation (prep) system market segments, market trends, and opportunities, and any further data you may need to thrive in the library preparation (prep) system industry. This library preparation (prep) system market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.
The library preparation (prep) system market size has grown rapidly in recent years. It will grow from $1.22 billion in 2024 to $1.37 billion in 2025 at a compound annual growth rate (CAGR) of 12.0%. The growth in the historic period can be linked to increasing demand for genomic sequencing, wider adoption of next-generation sequencing, growing awareness of genetic disorders, expansion of molecular diagnostics research, and rising government funding for genomics.
The library preparation (prep) system market size is expected to see rapid growth in the next few years. It will grow to $2.12 billion in 2029 at a compound annual growth rate (CAGR) of 11.6%. The growth in the forecast period can be linked to higher demand for precision therapeutics, increased investment in biopharmaceutical research, expansion of clinical genomics, and growing need for early disease detection. Key trends during the forecast period include innovations in library preparation kits, development of automated prep systems, emergence of high-throughput sequencing solutions, and integration of bioinformatics tools with prep systems.
The increasing adoption of personalized medicine is expected to drive the growth of the library preparation (prep) system market in the coming years. Personalized medicine is a medical approach that tailors treatment and prevention strategies based on an individual's unique genetic profile, lifestyle, and environment. This shift toward personalized medicine is largely due to advancements in genomics, which enable precise identification of genetic variations and the development of treatments that are specifically tailored to individuals. Library preparation (prep) systems play a crucial role in personalized medicine by enabling the accurate preparation of DNA and RNA samples, making them essential for precise genomic analysis. These systems streamline complex workflows, reduce errors, and accelerate the development of targeted therapies, ultimately improving patient-specific treatment outcomes. For example, in February 2024, the Personalized Medicine Coalition (PMC) reported that the FDA approved 26 new personalized medicines in 2023, a notable increase from 12 in 2022. As a result, the growing adoption of personalized medicine is driving the expansion of the library preparation (prep) system market.
Companies in the library preparation (prep) system market are focusing on developing advanced products, such as multimodal library preparation kits, to increase efficiency, enhance research capabilities, and minimize manual effort and sample material requirements. Multimodal library preparation kits are integrated solutions that allow for the simultaneous processing of both DNA and RNA from a single sample, enabling comprehensive genomic and transcriptomic analysis. For instance, in May 2024, Qiagen N.V., a Netherlands-based biotechnology company, introduced the QIAseq Multimodal DNA or RNA library kit. This innovative next-generation sequencing (NGS) kit is the first of its kind designed to prepare both DNA and RNA libraries from a single sample. The solution facilitates seamless preparation for whole genome sequencing (WGS) and whole transcriptome sequencing (WTS), featuring automated workflow integration and optimized chemistry to enable simultaneous DNA and RNA processing. This significantly reduces turnaround times and minimizes the use of sample material without requiring operator intervention.
In December 2023, PerkinElmer Inc., a US-based biotechnology firm, acquired Covaris LLC to enhance its NGS sample preparation capabilities. Through this acquisition, PerkinElmer aims to expand its NGS portfolio by adding Covaris' library prep systems and AFA instruments, improving its ability to provide high-quality, automated sample preparation solutions. Covaris LLC is a US-based biotechnology company that specializes in library preparation systems for next-generation sequencing.
Major players in the library preparation (prep) system market are F. Hoffmann-La Roche AG, Thermo Fisher Scientific Inc., Siemens Healthineers AG, Agilent Technologies Inc., Illumina Inc., Bio-Rad Laboratories Inc., QIAGEN N.V., Tecan Group Ltd., GenScript Biotech Corporation, Promega Corporation, Takara Bio Inc., Oxford Nanopore Technologies Limited, Pacific Biosciences of California Inc., New England Biolabs Inc., Singleron Biotechnologies Co. Ltd., Bionano Genomics Inc., Automata Technologies Ltd., Zymo Research Corporation, Dolomite Bio Limited, Micronit Microtechnologies B.V., Opentrons Labworks Inc., and EpigenDx Inc.
North America was the largest region in the library preparation (prep) system market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in library preparation (prep) system report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
The countries covered in the library preparation (prep) system market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The library preparation (prep) system market consists of revenues earned by entities by providing services such as nucleic acid extraction, library construction, sequencing-ready library generation, and workflow automation support. The market value includes the value of related goods sold by the service provider or included within the service offering. The library prep system market also includes sales of quality control (QC) tools for library prep, single-cell library preparation kits, adapter ligation kits, automation-ready library preparation kits, methylation library preparation kits, and whole-genome amplification kits. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).
The revenues for a specified geography are consumption values and are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Library Preparation (Prep) System Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on library preparation (prep) system market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for library preparation (prep) system ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The library preparation (prep) system market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.
 
                 
                 
                