PUBLISHER: The Business Research Company | PRODUCT CODE: 1945491
PUBLISHER: The Business Research Company | PRODUCT CODE: 1945491
Long-read sequencing refers to a deoxyribonucleic acid or ribonucleic acid sequencing method that produces relatively long continuous reads of nucleic acids, often ranging from thousands to millions of base pairs, compared to short-read techniques. It allows for more precise genome assembly, identification of structural variations, and analysis of complex genomic regions.
The main product and service categories of long-read sequencing are instruments or platforms, consumables and reagents, and services and software. Instruments or platforms refer to the sequencing devices and hardware used to conduct long-read sequencing. This includes workflows such as pre-sequencing, sequencing, and data analysis, and is supported by technology platforms including single molecule real-time (SMRT) high-fidelity (HiFi) sequencing, nanopore sequencing, synthetic long-read or linked-read, hybrid, and others. It is applied in human genomics and rare-disease diagnostics, oncology and liquid biopsy, metagenomics and microbiome, transcriptomics, agri-genomics and plant or animal breeding, and others, serving end users such as academic and research institutes, hospitals and clinics, pharmaceutical and biotechnology companies, and others.
Tariffs have raised costs of sequencing instruments, flow cells, and specialized consumables used in long-read sequencing. Asia-Pacific suppliers heavily impact global availability, particularly for nanopore and SMRT platforms. These costs have slowed adoption in research institutes. Positively, tariffs are encouraging regional manufacturing, platform innovation, and supply chain diversification.
The long-read sequencing market research report is one of a series of new reports from The Business Research Company that provides long-read sequencing market statistics, including long-read sequencing industry global market size, regional shares, competitors with a long-read sequencing market share, detailed long-read sequencing market segments, market trends and opportunities, and any further data you may need to thrive in the long-read sequencing industry. This long-read sequencing market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The long-read sequencing market size has grown exponentially in recent years. It will grow from $1.15 billion in 2025 to $1.46 billion in 2026 at a compound annual growth rate (CAGR) of 26.8%. The growth in the historic period can be attributed to limitations of short-read sequencing, growth of genomics research, technological breakthroughs in nanopore sequencing, demand for accurate genome assembly, increased funding in life sciences.
The long-read sequencing market size is expected to see exponential growth in the next few years. It will grow to $3.74 billion in 2030 at a compound annual growth rate (CAGR) of 26.5%. The growth in the forecast period can be attributed to clinical adoption of long-read sequencing, declining sequencing costs, integration with AI-based analysis, expansion in oncology diagnostics, growth of population genomics. Major trends in the forecast period include increasing adoption of long-read technologies, improved structural variant detection, growth of hybrid sequencing approaches, expansion of rare disease genomics, rising use in complex genome assembly.
The rising incidence of genetic disorders is anticipated to drive the expansion of the long-read sequencing market in the coming years. Genetic disorders are conditions caused by alterations or mutations in DNA, which can be inherited or occur spontaneously, impacting health, development, or bodily functions. The growing incidence of genetic disorders is attributed to heightened awareness and advances in diagnostic technologies, which allow for earlier and more precise identification of previously undiagnosed conditions. Long-read sequencing supports the management of genetic disorders by delivering highly accurate and comprehensive genomic insights, making it particularly suitable for diagnosing complex and rare conditions. It minimizes diagnostic uncertainty by identifying structural variations and intricate mutations, enhancing personalized treatment and clinical decision-making. For example, in October 2024, the Cystic Fibrosis Trust, a UK-based national charity, reported that the number of people living with cystic fibrosis (CF) in the UK increased from 11,148 in 2022 to 11,318 in 2023. Consequently, the rising incidence of genetic disorders is propelling the growth of the long-read sequencing market.
Leading companies in the long-read sequencing market are focusing on developing innovative solutions such as HiFi reads to improve sequencing accuracy, detect complex genetic variations, and accelerate genomic research. High-fidelity (HiFi) reads are long DNA sequences generated by advanced long-read sequencing technologies, offering both extended read lengths and extremely low error rates. This enables accurate detection of complex genetic variants and structural variations. For instance, in November 2024, Pacific Biosciences of California Inc. launched the Vega system, its first benchtop long-read sequencing platform. The Vega system provides highly accurate HiFi data with 99.9% read accuracy and enables faster, more accessible genomic analysis. This compact, affordable sequencer supports applications such as RNA sequencing, targeted sequencing, and small genome sequencing, bringing advanced genomics capabilities to more laboratories. The system simplifies workflows with onboard computing and user-friendly operation, helping researchers efficiently unlock complex genetic insights.
In March 2024, Clinical Microbiomics A/S, a Denmark-based multi-omics microbiome company, acquired DNASense ApS for an undisclosed sum. With this acquisition, Clinical Microbiomics aims to enhance its long-read sequencing capabilities for metagenomics, industrial, and environmental microbiome applications by incorporating DNASense's advanced long-read DNA and RNA sequencing technologies and high-resolution bioinformatics. DNASense ApS is a Denmark-based contract research organization (CRO) that specializes in long-read sequencing services and analytical workflows for DNA and RNA.
Major companies operating in the long-read sequencing market are Thermo Fisher Scientific Inc., Agilent Technologies Inc., Revvity Inc., Bio-Rad Laboratories Inc., BGI Genomics Co. Ltd., Novogene Co. Ltd., Takara Bio Inc., Oxford Nanopore Technologies plc, Pacific Biosciences of California Inc., New England Biolabs Inc., Roche Sequencing Solutions Inc., The Garvan Institute, Element Biosciences Inc., Eurofins Genomics, CD Genomics, BaseClear B.V, France Genomique, GrandOmics Biosciences Co. Ltd., Future Genomics Technologies B.V., MicrobesNG
North America was the largest region in the long-read sequencing market in 2025. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the long-read sequencing market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
The countries covered in the long-read sequencing market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Taiwan, Russia, South Korea, UK, USA, Canada, Italy, Spain
The long-read sequencing market consists of revenues earned by entities by providing services such as high-throughput DNA sequencing, real-time genome analysis, structural variant detection, and de novo genome assembly. The market value includes the value of related goods sold by the service provider or included within the service offering. The long-read sequencing market also includes sales of library preparation kits, analysis tools, and library and sample prep kits. Values in this market are 'factory gate' values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Long-Read Sequencing Market Global Report 2026 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses long-read sequencing market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for long-read sequencing ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The long-read sequencing market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, total addressable market (TAM), market attractiveness score (MAS), competitive landscape, market shares, company scoring matrix, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
Added Benefits available all on all list-price licence purchases, to be claimed at time of purchase. Customisations within report scope and limited to 20% of content and consultant support time limited to 8 hours.