PUBLISHER: The Business Research Company | PRODUCT CODE: 1947122
PUBLISHER: The Business Research Company | PRODUCT CODE: 1947122
Short-read sequencing, also known as next-generation sequencing (NGS), is a high-throughput DNA sequencing technique that produces short fragments or reads of DNA sequences. It has revolutionized genomics by facilitating the rapid and cost-effective analysis of entire genomes and transcriptomes.
The primary product categories in short-read sequencing comprise instruments, consumables, and services. Short-read sequencing instruments are the platforms or machines employed to generate short DNA fragments for analysis, allowing for the identification of genetic variations, mutations, and gene expression levels. Various technologies, including next-generation sequencing and Sanger sequencing, are utilized in workflows such as pre-sequencing, sequencing, and data analysis. These applications find use in clinical investigation, oncology, reproductive health, consumer genomics, agri genomics, forensics, HLA typing, and immune system monitoring. End users of short-read sequencing encompass academic research, hospitals and clinics, clinical research, and pharmaceutical and biotechnology companies.
Tariffs are impacting the short read sequencing market by increasing costs of imported sequencing instruments, optical components, reagents, flow cells, and data processing hardware. Research institutions and clinical laboratories in North America and Europe are most affected due to dependence on imported high-end sequencing systems, while Asia-Pacific faces pricing pressure on consumables supply. These tariffs are raising operational costs and slowing procurement of new platforms. However, they are also encouraging local manufacturing of sequencing consumables, regional supply chain diversification, and investment in domestic genomics infrastructure.
The short read sequencing market research report is one of a series of new reports from The Business Research Company that provides short read sequencing market statistics, including short read sequencing industry global market size, regional shares, competitors with a short read sequencing market share, detailed short read sequencing market segments, market trends and opportunities, and any further data you may need to thrive in the short read sequencing industry. This short read sequencing market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The short read sequencing market size has grown rapidly in recent years. It will grow from $7.8 billion in 2025 to $9.2 billion in 2026 at a compound annual growth rate (CAGR) of 17.9%. The growth in the historic period can be attributed to expansion of genomics research initiatives, declining cost per genome sequencing, increased use of NGS in academic research, growth of population-scale sequencing studies, wider availability of sequencing instruments.
The short read sequencing market size is expected to see rapid growth in the next few years. It will grow to $17.75 billion in 2030 at a compound annual growth rate (CAGR) of 17.9%. The growth in the forecast period can be attributed to increasing adoption of precision medicine programs, rising demand for oncology and rare disease sequencing, expansion of clinical diagnostics using NGS, growing investments in genomics data infrastructure, increasing use of AI-driven sequence analysis. Major trends in the forecast period include increasing adoption of high-throughput sequencing platforms, rising demand for cost-effective whole genome sequencing, growing integration of advanced bioinformatics pipelines, expansion of clinical and translational genomics applications, enhanced focus on sequencing accuracy and speed.
The increasing adoption of personalized medicine is driving growth in the short-read sequencing market. Personalized medicine customizes medical treatment according to an individual's genetic profile, enabling more precise and effective healthcare interventions. Short-read sequencing is critical for detecting genetic variations that influence drug response, supporting the development of tailored treatment plans. For instance, in February 2024, according to the Personalized Medicine Coalition, a US-based nonprofit organization, the US FDA approved 16 new personalized treatments for rare disease patients in 2023, up from six approvals in 2022. Therefore, the growing adoption of personalized medicine is boosting the short-read sequencing market.
Major companies in the short-read sequencing market are focusing on innovations such as hybrid long-/short-read sequencing assays to enhance analytical capabilities and improve access to complex genomic regions. A hybrid long-/short-read sequencing assay combines the generation of long and short sequencing reads on a single platform, providing higher genomic resolution while remaining compatible with standard high-throughput systems. For instance, in March 2023, Illumina Inc., a US-based provider of DNA sequencing and array-based technologies, launched the Illumina Complete Long Read Prep, Human assay. This product integrates long-read capability into existing short-read sequencing instruments, enabling laboratories to capture comprehensive genomic data without separate long-read systems. It supports low DNA input requirements and maintains high accuracy, improving the analysis of difficult-to-map genomic regions while simplifying workflows.
In March 2023, QIAGEN N.V., a Germany-based provider of sample and assay technologies, including short-read sequencing, formed a partnership with Sophia Genetics SA. This collaboration aims to enhance next-generation sequencing (NGS) capabilities by integrating QIAGEN's QIAseq reagent technology with SOPHiA's DDM (Digital Data Management) platform, facilitating improved tumor analysis and somatic variant detection. Sophia Genetics SA is a Switzerland-based company specializing in medical software.
Major companies operating in the short read sequencing market are F. Hoffmann-La Roche AG, Thermo Fisher Scientific Inc., Illumina Inc., Agilent Technologies Inc., QIAGEN N.V., PerkinElmer Inc., Eurofins Scientific SE, BGI Genomics Co Ltd, MGI Tech Co. Ltd., 10x Genomics Inc., Zymo Research Corporation, Paragon Genomics Inc., Novogene Co. Ltd, Macrogen Inc., Fasteris SA, GenScript Biotech Corporation, Element Biosciences Inc., Singular Genomics Systems Inc., Ultima Genomics Inc., GenapSys Inc.
North America was the largest region in the Short Read Sequencing market in 2025. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the short read sequencing market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
The countries covered in the short read sequencing market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Taiwan, Russia, South Korea, UK, USA, Canada, Italy, Spain
The short-read sequencing market includes revenues earned by entities by providing short-read sequencing services such as sequencing services, bioinformatics, sample processing, sequencing runs, data generation, and analysis. The market value includes the value of related goods sold by the service provider or included within the service offering. The short-read sequencing market also consists of sales-related products such as sequencing instruments, reagents, and consumables. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Short Read Sequencing Market Global Report 2026 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses short read sequencing market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for short read sequencing ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The short read sequencing market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, total addressable market (TAM), market attractiveness score (MAS), competitive landscape, market shares, company scoring matrix, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
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