PUBLISHER: The Business Research Company | PRODUCT CODE: 1955383
PUBLISHER: The Business Research Company | PRODUCT CODE: 1955383
Gene synthesis involves the chemical construction of a DNA (deoxyribonucleic acid) strand by sequentially assembling nucleotides base by base. This technique is applied across a wide range of uses, including the creation of recombinant DNA molecules, protein engineering, gene therapy, and synthetic biology.
The main methods of gene synthesis include solid-phase synthesis, chip-based synthesis, and PCR-based enzyme synthesis. Solid-phase synthesis refers to a process in which the target molecule is chemically attached to an insoluble support while reagents are added in the solution phase. This approach supports various gene synthesis services such as antibody DNA synthesis, viral DNA synthesis, and others, which are used in applications including gene and cell therapy development, vaccine development, disease diagnosis, and others. Gene synthesis is utilized by end users such as biotechnology and pharmaceutical companies, academic and government research institutes, and contract research organizations.
Tariffs have affected the gene synthesis market by increasing the cost of imported reagents, enzymes, and synthesis equipment, leading to higher production costs for biotechnology and pharmaceutical companies. The solid-phase synthesis and PCR-based enzyme synthesis segments are most impacted, particularly in North America and Europe, where imports from Asia are significant. Despite these challenges, tariffs have encouraged local manufacturing and supply chain diversification, potentially boosting domestic production capabilities and innovation within the market.
The gene synthesis market research report is one of a series of new reports from The Business Research Company that provides gene synthesis market statistics, including gene synthesis industry global market size, regional shares, competitors with a gene synthesis market share, detailed gene synthesis market segments, market trends and opportunities, and any further data you may need to thrive in the gene synthesis industry. This gene synthesis market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The gene synthesis market size has grown exponentially in recent years. It will grow from $3.95 billion in 2025 to $4.76 billion in 2026 at a compound annual growth rate (CAGR) of 20.7%. The growth in the historic period can be attributed to advancements in recombinant dna technology, increased r&d in pharmaceuticals, adoption of automated synthesis platforms, growth of academic research institutes, rising demand for gene editing tools.
The gene synthesis market size is expected to see exponential growth in the next few years. It will grow to $10.44 billion in 2030 at a compound annual growth rate (CAGR) of 21.7%. The growth in the forecast period can be attributed to rise in gene and cell therapy development, increasing investment in synthetic biology, growing vaccine development initiatives, expansion of contract research organizations, increasing use of viral dna synthesis in diagnostics. Major trends in the forecast period include expansion of synthetic biology applications, growth of personalized gene therapies, increased demand for high-fidelity dna synthesis, advancements in enzyme-based synthesis techniques, rising academic and government research initiatives.
The increasing demand for biofuels is anticipated to drive the expansion of the gene synthesis market in the coming years. Biofuels are renewable energy sources produced from organic materials such as plant matter or animal waste and are used as alternatives to conventional fossil fuels. Gene synthesis plays a vital role in biofuel production by enabling the engineering of microorganisms with optimized metabolic pathways that improve the conversion efficiency of organic feedstocks into biofuels. For example, in June 2023, according to the International Energy Agency, a France-based intergovernmental organization, biofuel demand in advanced economies is projected to increase by 6%, or approximately 5,700 million liters, between 2022 and 2024, with the majority of this growth occurring in the United States and Europe. As a result, the rising demand for biofuels is contributing to the growth of the gene synthesis market.
Major companies operating in the gene synthesis market are concentrating on the development of advanced platforms, such as silicon-based DNA synthesis technologies, to enable faster turnaround times and strengthen their competitive position. Silicon-based DNA synthesis platforms use silicon wafers to miniaturize and streamline the chemical reactions required for DNA assembly, allowing high-throughput and rapid gene synthesis. For instance, in November 2023, Twist Bioscience Corporation, a US-based biotechnology company, introduced Twist Express Genes, a rapid gene synthesis service offering turnaround times of five to seven business days. This service leverages a silicon-based DNA synthesis platform to meet customer demand for accelerated delivery. Twist Express Genes is designed to serve both industrial and academic researchers who purchase DNA externally or synthesize genes in-house, providing a flexible and efficient gene production solution while ensuring high quality and sequence accuracy.
In January 2023, Moderna Inc., a US-based biotechnology company, acquired OriCiro Genomics for an undisclosed amount. Through this acquisition, Moderna aims to strengthen its mRNA manufacturing capabilities and accelerate the development of its therapeutic and vaccine pipeline. OriCiro Genomics is a Japan-based biotechnology company specializing in synthetic biology and DNA synthesis technologies.
Major companies operating in the gene synthesis market are Genscript Biotech Corporation, Twist Bioscience Corp., ProteoGenix Inc., Biomatik Corporation, ProMab Biotechnologies Inc., Thermo Fisher Scientific Inc., Integrated DNA Technologies Inc., OriGene Technologies Inc., GenScript Corp., Merck KGaA, Codex DNA Inc., Genewiz Inc., Eurofins Genomics LLC, BioCat GmbH, Bioneer Pacific Co. Ltd., Bio Basic Inc., Beijing SBS Genetech Co. Ltd, Creative Biogene Inc, Exonbio LLC., Trenzyme GmbH, Polygen GmbH, MACROGEN CO. LTD., Synbio Technologies LLC
North America was the largest region in the gene synthesis market in 2025. Asia-Pacific is expected to be the fastest-growing region in the global gene synthesis market report during the forecast period. The regions covered in the gene synthesis market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
The countries covered in the gene synthesis market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Taiwan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The gene synthesis market includes revenues earned by entities by providing custom gene synthesis services, selling pre-made DNA constructs, genetic engineering, vaccine development, antibody discovery, protein engineering, licensing technology, forming partnerships, and collaborating on research projects. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Gene Synthesis Market Global Report 2026 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses gene synthesis market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for gene synthesis ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The gene synthesis market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, total addressable market (TAM), market attractiveness score (MAS), competitive landscape, market shares, company scoring matrix, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
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