PUBLISHER: The Business Research Company | PRODUCT CODE: 1955448
PUBLISHER: The Business Research Company | PRODUCT CODE: 1955448
Human serum albumin is a protein present in human blood plasma that plays a vital role in maintaining oncotic pressure, which regulates the movement of water between blood vessels and body tissues. It also transports hormones, fatty acids, and other compounds, buffers pH, and binds various drugs, making it essential for numerous physiological functions.
The main types of human serum albumin preparations are recombinant human serum albumin and plasma-derived human serum albumin. Recombinant human serum albumin is a lab-produced version made using genetically modified cells, such as yeast or bacteria. These preparations are available in different formulations, including injection solutions and lyophilized powder, and are distributed through various channels such as direct sales, online pharmacies, third-party distributors, and hospital pharmacies. They are used in applications such as volume expansion, drug delivery systems, nutritional support, and diagnostic agents, serving end users including hospitals, research laboratories, pharmaceutical companies, and blood banks.
Tariffs have affected the human serum albumin market by increasing costs of imported plasma, recombinant HSA, and advanced formulation equipment. Segments such as recombinant HSA and plasma-derived HSA solutions are most impacted, particularly in North America, Europe, and Asia-Pacific regions where imports are significant. This has led to higher production and procurement costs. On the positive side, tariffs have encouraged local manufacturing, investment in recombinant technology, and development of cost-optimized HSA formulations.
The human serum albumin market research report is one of a series of new reports from The Business Research Company that provides human serum albumin market statistics, including human serum albumin industry global market size, regional shares, competitors with a human serum albumin market share, detailed human serum albumin market segments, market trends and opportunities, and any further data you may need to thrive in the human serum albumin industry. This human serum albumin market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The human serum albumin market size has grown strongly in recent years. It will grow from $5.79 billion in 2025 to $6.21 billion in 2026 at a compound annual growth rate (CAGR) of 7.3%. The growth in the historic period can be attributed to limited availability of recombinant hsa, reliance on plasma-derived hsa, growing hospital and clinical demand, increasing use in diagnostic and therapeutic applications, adoption of standard injection solutions.
The human serum albumin market size is expected to see strong growth in the next few years. It will grow to $8.16 billion in 2030 at a compound annual growth rate (CAGR) of 7.0%. The growth in the forecast period can be attributed to development of yeast, bacterial, and plant-based recombinant hsa, rising demand for fatty acid-free formulations, expansion of drug delivery and nutrition enhancement applications, increasing investment in research laboratories, growth in hospital and blood bank procurement. Major trends in the forecast period include rising demand for plasma-derived and recombinant human serum albumin, growth in use of hsa in volume expanders and drug delivery systems, increasing adoption of lyophilized powder and injection solutions, expansion of hospital and research laboratory applications, focus on fatty acid-free and specialty hsa preparations.
The rising occurrence of liver diseases is anticipated to drive the expansion of the human serum albumin market in the coming years. Liver diseases encompass a range of conditions that impair liver function, such as hepatitis, fatty liver disease, cirrhosis, and liver cancer. The increase in these conditions is largely attributed to the growing prevalence of obesity, as excess abdominal fat contributes to non-alcoholic fatty liver disease (NAFLD), leading to fat buildup, inflammation, and possible liver failure. Human serum albumin supports the management of liver disease by restoring blood volume, reducing fluid retention, safeguarding kidney function, and improving outcomes in complications like ascites and hepatorenal syndrome. For example, in December 2024, a report from the Office for Health Improvement and Disparities, a UK government agency, revealed that premature deaths from alcoholic liver disease rose by 3.6% in 2023, reaching 5,984 cases compared to 5,776 in 2022. Consequently, the growing prevalence of liver diseases is fueling the demand for human serum albumin.
Leading companies in the human serum albumin market are concentrating on creating advanced solutions, such as animal-free recombinant excipients, to improve product safety, scalability, and adherence to regulatory standards in biomanufacturing. An animal-free recombinant excipient is a biologically engineered inactive substance developed using recombinant DNA technology without animal or human-derived components, ensuring high purity and safety in pharmaceutical and biomanufacturing processes. For instance, in April 2025, InVitri Inc., a US-based provider of recombinant proteins and excipients, introduced Optibumin 25, the first recombinant 25% human serum albumin designed for closed-system biomanufacturing. This product is optimized for downstream processing, formulation, and cryopreservation workflows, and is available in 100 mL single-use bags. With its animal-origin-free and chemically defined composition, it delivers high purity, consistency, and reduced contamination risks. It is GMP-ready, scalable to commercial production levels, and provides a stable, sterile solution that integrates seamlessly into applications such as viral vector manufacturing, stem cell preservation, vaccine formulation, and regenerative medicine.
In June 2024, Proliant Health and Biologicals, a US-based manufacturer, collaborated with Dyadic International Inc. to bring animal-free recombinant human serum albumin to market. Through this partnership, Proliant and Dyadic aim to accelerate production and availability of scalable, non-animal-derived albumin for diagnostics, cell culture, nutrition, and therapeutic uses by combining Proliant's expertise in purified-protein manufacturing and commercial distribution with Dyadic's C1 microbial expression platform. This collaboration seeks to strengthen supply-chain resilience, reduce dependence on plasma-derived materials, and meet regulatory and customer requirements for GMP-grade recombinant proteins. Dyadic International Inc. is a US biotechnology company specializing in large-scale microbial production platforms, including the C1 system, for manufacturing recombinant proteins and other biologics.
Major companies operating in the human serum albumin market are Thermo Fisher Scientific Inc., Takeda Pharmaceutical Company Limited, Merck KGaA, CSL Behring (CSL), Baxter International Inc., Grifols SA, Sartorius AG, Octapharma AG, Kedrion Biopharma, Shanghai RAAS Blood Products Co Ltd., Biotest Aktiengesellschaft, LFB Group, Hualan Biological Engineering Inc., Taibang Biologic Group, Kamada Ltd., InVitria Inc., Reliance Life Sciences, Bio Products Laboratory, Mitsubishi Tanabe Pharma, Sichuan Yuanda Shuyang Pharmaceutical Co Ltd.
North America was the largest region in the human serum albumin market in 2025. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the human serum albumin market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
The countries covered in the human serum albumin market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Taiwan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The human serum albumin market consists of sales of human serum albumin injection, plasma-derived albumin, albumin-based drug delivery systems, and albumin solutions for cell culture and diagnostics. Values in this market are 'factory gate' values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Human Serum Albumin Market Global Report 2026 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses human serum albumin market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for human serum albumin ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The human serum albumin market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, total addressable market (TAM), market attractiveness score (MAS), competitive landscape, market shares, company scoring matrix, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
Added Benefits available all on all list-price licence purchases, to be claimed at time of purchase. Customisations within report scope and limited to 20% of content and consultant support time limited to 8 hours.