PUBLISHER: The Business Research Company | PRODUCT CODE: 1957508
PUBLISHER: The Business Research Company | PRODUCT CODE: 1957508
Non-alcoholic steatohepatitis (NASH) treatment involves approaches such as maintaining a healthy diet, controlling blood sugar, and promoting weight and fat loss. NASH is a liver disease where individuals, who consume little or no alcohol, develop fatty livers, leading to liver cell damage and inflammation. If untreated, this can progress to cirrhosis.
The main drugs used in NASH treatment include vitamin E, pioglitazone, ocaliva, elafibranor, selonsertib, cenicriviroc, obeticholic acid, and others. Vitamin E is a fat-soluble nutrient that helps reduce oxidative stress in liver cells, reducing liver damage and inflammation, while pioglitazone works to improve insulin sensitivity and manage high blood sugar levels, often linked to type 2 diabetes. Diagnostic tests such as blood tests, liver biopsies, and imaging procedures are used to monitor the condition, with treatment distributed through hospital pharmacies, retail pharmacies, and specialty pharmacies.
Tariffs have influenced the non-alcoholic steatohepatitis treatment market by affecting the cost and availability of imported active pharmaceutical ingredients (APIs) and advanced diagnostic equipment. This has increased production costs for drugs like pioglitazone and obeticholic acid, particularly impacting Asia-Pacific suppliers and distributors. Hospital pharmacies and specialty drug segments are most affected, while some domestic manufacturers benefit from protective tariffs by gaining a competitive advantage in local markets.
The non-alcoholic steatohepatitis treatment market research report is one of a series of new reports from The Business Research Company that provides non-alcoholic steatohepatitis treatment market statistics, including non-alcoholic steatohepatitis treatment industry global market size, regional shares, competitors with a non-alcoholic steatohepatitis treatment market share, detailed non-alcoholic steatohepatitis treatment market segments, market trends and opportunities, and any further data you may need to thrive in the non-alcoholic steatohepatitis treatment industry. This non-alcoholic steatohepatitis treatment market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The non-alcoholic steatohepatitis treatment market size has grown exponentially in recent years. It will grow from $3.57 billion in 2025 to $4.98 billion in 2026 at a compound annual growth rate (CAGR) of 39.6%. The growth in the historic period can be attributed to rising prevalence of obesity, increasing incidence of type 2 diabetes, high consumption of processed foods, lack of awareness about liver health, limited treatment options for early-stage nash.
The non-alcoholic steatohepatitis treatment market size is expected to see exponential growth in the next few years. It will grow to $18.97 billion in 2030 at a compound annual growth rate (CAGR) of 39.7%. The growth in the forecast period can be attributed to advancements in precision medicine, development of novel nash drugs, adoption of digital health monitoring tools, government initiatives for liver disease prevention, increasing investment in liver disease research. Major trends in the forecast period include personalized lifestyle & diet management, non-invasive diagnostic advancements, fatty liver disease awareness programs, home-based liver health monitoring, novel pharmacological agents development.
The increasing prevalence of insulin resistance has driven the growth of the non-alcoholic steatohepatitis (NASH) treatment market. Insulin resistance occurs when cells in muscles, fat, and the liver do not respond effectively to insulin, resulting in high blood sugar levels. It is commonly linked to an unhealthy lifestyle, excessive sugar intake, and genetic factors. The rise in insulin resistance has been associated with an increase in diabetes and other liver-related issues, conditions that are often treated with NASH therapies. For example, in July 2025, PubMed, a U.S.-based biomedical literature database, reported a significant increase in the prevalence of obesity, abdominal obesity, severe obesity, and insulin resistance, with rates rising from 34.9% to 41.4%, 62.5% to 67.0%, 5.2% to 11.5%, and 22.5% to 30.2%, respectively. Consequently, the growing prevalence of insulin resistance due to liver and diabetes-related diseases is expected to propel the NASH treatment market.
Major companies in the non-alcoholic steatohepatitis (NASH) treatment market are focusing on innovative products like endogenous hormones to expand their customer bases, increase sales, and drive revenue growth. Endogenous hormones are naturally occurring substances in the body that regulate various physiological functions. For example, in September 2023, 89bio Inc., a U.S.-based biotechnology company, announced that the U.S. Food and Drug Administration (FDA) granted Breakthrough Therapy Designation (BTD) for Pegozafermin in individuals diagnosed with NASH. Pegozafermin is an engineered glycoPEGylated analog of fibroblast growth factor 21 (FGF21). This innovative product is being developed for NASH and severe hypertriglyceridemia (SHTG). The use of glycoPEGylated technology in Pegozafermin gives it an extended half-life while preserving its potency, enhancing its ability to modulate key factors such as triglyceride reduction, glycemic control, steatosis, inflammation, and fibrosis.
In September 2023, Kriya Therapeutics, a U.S.-based biotechnology company focused on gene therapy for metabolic and neurodegenerative diseases, acquired Tramontane Therapeutics for an undisclosed amount. This acquisition enhances Kriya's NASH treatment pipeline by adding a one-time gene therapy program targeting Fibroblast Growth Factor 21 (FGF21), further strengthening its capabilities in metabolic-liver disease therapeutics. Tramontane Therapeutics, a Spain-based biotechnology company, specializes in gene therapy programs for metabolic and neurodegenerative diseases, and its lead candidate for NASH utilizes AAV-mediated FGF21 expression.
Major companies operating in the non-alcoholic steatohepatitis treatment market are AstraZeneca PLC, Galmed Pharmaceuticals Ltd., Genfit S.A., Zydus Cadila Healthcare Limited, Bristol-Myers Squibb Company, Gilead Sciences Inc., Novo Nordisk A/S, Inventiva Pharma SA, NGM Biopharmaceuticals Inc., Galectin Therapeutics Inc., Madrigal Pharmaceuticals Corporation, Intercept Pharmaceuticals Inc., Cirius Therapeutics Inc., Viking Therapeutics Inc., Eli Lilly and Company, Terns Pharmaceuticals Inc., AbbVie Inc., Johnson & Johnson Private Limited, Sanofi S.A., F. Hoffmann-La Roche Ltd., C.H. Boehringer Sohn AG & Co. KG
North America was the largest region in the non-alcoholic steatohepatitis treatment market share in 2025. The regions covered in the non-alcoholic steatohepatitis treatment market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
The countries covered in the non-alcoholic steatohepatitis treatment market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Taiwan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The non-alcoholic steatohepatitis treatment market includes revenues earned by entities by providing services such as liver related ?medical diagnosis and tests, fatty liver management and treatment, abdominal ultrasound. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Non-Alcoholic Steatohepatitis Treatment Market Global Report 2026 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses non-alcoholic steatohepatitis treatment market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for non-alcoholic steatohepatitis treatment ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The non-alcoholic steatohepatitis treatment market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, total addressable market (TAM), market attractiveness score (MAS), competitive landscape, market shares, company scoring matrix, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
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