PUBLISHER: The Insight Partners | PRODUCT CODE: 1871423
PUBLISHER: The Insight Partners | PRODUCT CODE: 1871423
The North America microelectrode array in vitro market was valued at approximately US$ 8.44 million in 2023 and is projected to grow to US$ 11.94 million by 2031, reflecting a compound annual growth rate (CAGR) of 4.4% during this period.
Increasing Demand in Neuroscience Research
The rising demand for microelectrode arrays (MEAs) in neuroscience research is a significant driver of the North American market. These arrays are essential for testing new pharmaceuticals on neuronal cultures, allowing researchers to evaluate the impact of drugs on neural activity and develop targeted therapies. In vitro models are utilized to study a range of neurological and neuropsychiatric disorders, including Alzheimer's disease, Parkinson's disease, epilepsy, and various neurodevelopmental conditions. The growing prevalence of these disorders has led to an increased need for microelectrode array systems, which facilitate the examination of cellular and molecular changes associated with these diseases and their effects on neural functions.
By employing microelectrode arrays in in vitro cell models, researchers can measure neural activity and assess how drug compounds can modulate this activity, restore normal network function, or counteract disease-related abnormalities. This capability is crucial for identifying promising drug candidates early in the development process. As neuroscience research continues to expand, companies like Axion BioSystems, Multi Channel Systems, and MaxWell Biosystems are innovating and launching new products to meet this demand. For example, in April 2024, Axion BioSystems introduced the Maestro Volt, a cost-effective benchtop microelectrode array system designed for academic laboratories with lower throughput requirements. This 6-well device is suitable for both neurological and cardiovascular research, featuring user-friendly controls and high-quality standards associated with the Maestro brand.
North America Market Overview
Investors are increasingly interested in companies that manufacture high-throughput microelectrode arrays for in vitro research, which are essential for research institutions, pharmaceutical companies, and the biotechnology sector. Innovations in CMOS-based microelectrode arrays, stem cell research, neuroprosthetics, and in vitro toxicology testing are propelling the demand for these technologies. Notably, in June 2020, the Georgia State University Research Foundation received US$ 197.56 million from the US National Science Foundation to develop microelectrode array sensors for SARS-CoV-2 and other RNA viruses, showcasing the potential of these technologies to address global health challenges.
The US Environmental Protection Agency has also recognized microelectrode arrays as valuable tools for conducting in vitro toxicity tests, particularly for assessing developmental neurotoxicity, which poses significant challenges in the approval of new chemicals and drugs. Such regulatory support has led to increased use of microelectrode arrays for high-throughput screening in drug discovery and disease modeling, as researchers seek reliable platforms for real-time monitoring of cellular and tissue activity.
The adoption of microelectrode arrays in innovative in vitro models, such as organoids, has spurred the development of advanced technologies, including 3D microelectrode array technology and high-density CMOS-based microelectrode arrays. For instance, in January 2023, BMSEED, a US-based provider of microelectrode array technologies, filed a patent application for its 2D stretchable microelectrode array (sMEA) that has been enhanced into a 3D version, allowing for electrophysiological measurements from brain organoids and 3D tissue cultures, particularly in Alzheimer's research. This 3D-sMEA technology features adjustable pockets with embedded electrodes that conform to organoids, enabling researchers to capture neural signals from approximately 80% of the surface area of intact organoids.
Market Segmentation
The North America microelectrode array in vitro market is segmented by product, application, and country. In terms of product, the market is divided into classical MEA, multiwell-MEA, and CMOS-MEA, with the multiwell-MEA segment holding the largest market share in 2023. Regarding application, the market is categorized into cardiomyocytes, nerve, and others, with the cardiomyocytes segment also leading in market share. By country, the market is segmented into the US, Canada, and Mexico, with the US dominating the market in 2023.
Key Players
Leading companies in the North America microelectrode array in vitro market include Tucker Davis Technologies, SCREEN Holdings Co., Ltd., Plexon Inc., MaxWell Biosystems AG, Harvard Bioscience Inc., Axion BioSystems Inc., 3Brain AG, NeuroNexus Technologies Inc., MicroElectrodeDevices, Blackrock Microsystems, Inc., NMI Technologietransfer GmbH, and BMSEED. These companies are at the forefront of developing innovative solutions to meet the growing demands of neuroscience and related fields.