Biosimilar Contract Manufacturing Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Product, By Technology, By Application, By Region and Competition, 2020-2030F

Description

Global Biosimilar Contract Manufacturing Market was valued at USD 9.37 billion in 2024 and is expected to reach USD 23.54 billion by 2030 with a CAGR of 16.59% during the forecast period. The global market for Biosimilar Contract Manufacturing is experiencing significant growth, driven by the growing prevalence of various chronic diseases. Additionally, increasing availability of cancer biosimilars with lowered prices and affordable treatment, along with the growing adoption of cost-effective healthcare systems across the globe, have increased the demand for biosimilar contract manufacturing. Additionally, the growing geriatric population across the globe, susceptible to different kinds of chronic diseases, is further expected to increase the demand for biosimilar contract manufacturing.

Market Overview
Forecast Period	2026-2030
Market Size 2024	USD 9.37 Billion
Market Size 2030	USD 23.54 Billion
CAGR 2025-2030	16.59%
Fastest Growing Segment	Oncology
Largest Market	North America

Key Market Drivers

Patent Expiry of Biologics Encouraging Biosimilar Development

The expiration of patents on many blockbusters biologic drugs has created a significant opportunity for biosimilar development, directly driving the demand for contract manufacturing organizations (CMOs) that specialize in biosimilar production. Biologics such as trastuzumab, bevacizumab, and adalimumab have either lost or are nearing the expiration of their exclusivity periods in multiple regions including the U.S., Europe, and parts of Asia. This opens the door for biosimilar manufacturers to introduce more cost-effective alternatives.

CMOs play a pivotal role in facilitating this transition by providing the infrastructure, expertise, and regulatory guidance required to bring these complex products to market efficiently. According to the U.S. Food and Drug Administration (FDA), as of 2024, over 40 biosimilars have been approved in the United States, a marked increase compared to just 11 approvals five years earlier. The European Medicines Agency (EMA) also reports steady growth in biosimilar approvals since its first authorization in 2006, reflecting a regulatory climate conducive to biosimilar uptake. The challenge of producing biologics-due to their complexity, the need for sterile environments, and sophisticated analytical testing-makes contract manufacturing a strategic choice for many biosimilar developers. Rather than investing in costly facilities and process development, pharmaceutical companies are increasingly outsourcing CMOs that already possess these capabilities, thus speeding up time-to-market and reducing capital expenditure.

Key Market Challenges

High Complexity and Cost of Biosimilar Manufacturing

Despite their economic appeal, biosimilars are biologically complex molecules that require sophisticated manufacturing infrastructure, highly skilled personnel, and rigorous quality control systems. Developing biosimilars involves extensive comparative analytical studies and process validation steps to ensure therapeutic equivalence to the original biologic, which significantly increases development time and cost. Even with outsourcing to CMOs, the cost of manufacturing biosimilars can be prohibitively high, particularly for smaller biotech firms or those targeting niche therapeutic areas. Governments such as the U.S. FDA and EMA require a comprehensive dossier of quality, safety, and efficacy data before approving a biosimilar, further increasing regulatory and financial burdens.

Moreover, CMOs must make substantial upfront investments in specialized bioreactors, cell culture facilities, and cleanroom environments to accommodate biosimilar projects. These capital-intensive requirements limit the number of CMOs equipped to handle large-scale biosimilar contracts, creating a bottleneck in supply and potentially slowing market growth.

Key Market Trends

Rise of Single-Use Bioprocessing Technologies in Biosimilar Manufacturing

One of the most prominent trends reshaping the biosimilar contract manufacturing landscape is the widespread adoption of single-use bioprocessing technologies. Single-use systems-comprising disposable bioreactors, mixing systems, and filtration units-offer significant advantages over traditional stainless-steel equipment, including reduced contamination risk, lower cleaning validation costs, and faster turnaround times between batches.

These benefits are particularly relevant in the biosimilar space, where cost efficiency and speed to market are critical. CMOs are increasingly incorporating single-use technologies to enhance their operational flexibility and meet the unique production needs of multiple clients simultaneously. According to the U.S. Department of Commerce, biopharmaceutical manufacturers who adopt single-use systems report a 30-50% reduction in production costs, making this approach especially attractive for biosimilar developers operating on tight margins.

Furthermore, these technologies support small and medium-sized batches, aligning well with the growing trend of personalized medicine and targeted biosimilars. The ability to quickly scale up or down based on demand also makes contract manufacturing more agile and responsive to fluctuating market needs.

Key Market Players

Catalent, Inc.
Boehringer Ingelheim GmbH
Alcami Corporation, Inc.
Almac Group
Lonza Group AG
Biocon Limited
Avid Bioservice, Inc.
Rentschler Biopharma SE
Fujifilm Kyowa Kirin Biologics Co., Ltd.
WuXi Biologics, Inc.

Report Scope:

In this report, the Global Biosimilar Contract Manufacturing Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

Biosimilar Contract Manufacturing Market, By Product:

Recombinant Non-glycosylated Proteins
Recombinant Glycosylated Proteins

Biosimilar Contract Manufacturing Market, By Technology:

Mammalian
Non-Mammalian

Biosimilar Contract Manufacturing Market, By Application:

Oncology
Blood Disorders
Growth Hormonal Deficiency
Chronic & Autoimmune Disorders
Rheumatoid Arthritis
Others

Biosimilar Contract Manufacturing Market, By Region:

North America
- United States
- Mexico
- Canada
Europe
- France
- Germany
- United Kingdom
- Italy
- Spain
Asia-Pacific
- China
- India
- South Korea
- Japan
- Australia
South America
- Brazil
- Argentina
- Colombia
Middle East and Africa
- South Africa
- Saudi Arabia
- UAE

Competitive Landscape

Company Profiles: Detailed analysis of the major companies presents in the Global Biosimilar Contract Manufacturing Market.

Available Customizations:

Global Biosimilar Contract Manufacturing Market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

1. Service Overview

1.1. Market Definition
1.2. Scope of the Market
- 1.2.1. Markets Covered
- 1.2.2. Years Considered for Study
- 1.2.3. Key Market Segmentations

2. Research Methodology

2.1. Objective of the Study
2.2. Baseline Methodology
2.3. Key Industry Partners
2.4. Major Association and Secondary Sources
2.5. Forecasting Methodology
2.6. Data Triangulation & Validation
2.7. Assumptions and Limitations

3. Executive Summary

3.1. Overview of the Market
3.2. Overview of Key Market Segmentations
3.3. Overview of Key Market Players
3.4. Overview of Key Regions/Countries
3.5. Overview of Market Drivers, Challenges, Trends

4. Voice of Customer

5. Global Biosimilar Contract Manufacturing Market Outlook

5.1. Market Size & Forecast
- 5.1.1. By Value
5.2. Market Share & Forecast
- 5.2.1. By Product (Recombinant Non-glycosylated Proteins, Recombinant Glycosylated Proteins)
- 5.2.2. By Technology (Mammalian, Non-Mammalian)
- 5.2.3. By Application (Oncology, Blood Disorders, Growth Hormonal Deficiency, Chronic & Autoimmune Disorders, Rheumatoid Arthritis, Others)
- 5.2.4. By Region
- 5.2.5. By Company (2024)
5.3. Market Map
- 5.3.1. By Product
- 5.3.2. By Technology
- 5.3.3. By Application
- 5.3.4. By Region

6. North America Biosimilar Contract Manufacturing Market Outlook

6.1. Market Size & Forecast
- 6.1.1. By Value
6.2. Market Share & Forecast
- 6.2.1. By Product
- 6.2.2. By Technology
- 6.2.3. By Application
- 6.2.4. By Country
6.3. North America: Country Analysis
- 6.3.1. United States Biosimilar Contract Manufacturing Market Outlook
  - 6.3.1.1. Market Size & Forecast
    - 6.3.1.1.1. By Value
  - 6.3.1.2. Market Share & Forecast
    - 6.3.1.2.1. By Product
    - 6.3.1.2.2. By Technology
    - 6.3.1.2.3. By Application
- 6.3.2. Canada Biosimilar Contract Manufacturing Market Outlook
  - 6.3.2.1. Market Size & Forecast
    - 6.3.2.1.1. By Value
  - 6.3.2.2. Market Share & Forecast
    - 6.3.2.2.1. By Product
    - 6.3.2.2.2. By Technology
    - 6.3.2.2.3. By Application
- 6.3.3. Mexico Biosimilar Contract Manufacturing Market Outlook
  - 6.3.3.1. Market Size & Forecast
    - 6.3.3.1.1. By Value
  - 6.3.3.2. Market Share & Forecast
    - 6.3.3.2.1. By Product
    - 6.3.3.2.2. By Technology
    - 6.3.3.2.3. By Application

7. Europe Biosimilar Contract Manufacturing Market Outlook

7.1. Market Size & Forecast
- 7.1.1. By Value
7.2. Market Share & Forecast
- 7.2.1. By Product
- 7.2.2. By Technology
- 7.2.3. By Application
- 7.2.4. By Country
7.3. Europe: Country Analysis
- 7.3.1. France Biosimilar Contract Manufacturing Market Outlook
  - 7.3.1.1. Market Size & Forecast
    - 7.3.1.1.1. By Value
  - 7.3.1.2. Market Share & Forecast
    - 7.3.1.2.1. By Product
    - 7.3.1.2.2. By Technology
    - 7.3.1.2.3. By Application
- 7.3.2. Germany Biosimilar Contract Manufacturing Market Outlook
  - 7.3.2.1. Market Size & Forecast
    - 7.3.2.1.1. By Value
  - 7.3.2.2. Market Share & Forecast
    - 7.3.2.2.1. By Product
    - 7.3.2.2.2. By Technology
    - 7.3.2.2.3. By Application
- 7.3.3. United Kingdom Biosimilar Contract Manufacturing Market Outlook
  - 7.3.3.1. Market Size & Forecast
    - 7.3.3.1.1. By Value
  - 7.3.3.2. Market Share & Forecast
    - 7.3.3.2.1. By Product
    - 7.3.3.2.2. By Technology
    - 7.3.3.2.3. By Application
- 7.3.4. Italy Biosimilar Contract Manufacturing Market Outlook
  - 7.3.4.1. Market Size & Forecast
    - 7.3.4.1.1. By Value
  - 7.3.4.2. Market Share & Forecast
    - 7.3.4.2.1. By Product
    - 7.3.4.2.2. By Technology
    - 7.3.4.2.3. By Application
- 7.3.5. Spain Biosimilar Contract Manufacturing Market Outlook
  - 7.3.5.1. Market Size & Forecast
    - 7.3.5.1.1. By Value
  - 7.3.5.2. Market Share & Forecast
    - 7.3.5.2.1. By Product
    - 7.3.5.2.2. By Technology
    - 7.3.5.2.3. By Application

8. Asia-Pacific Biosimilar Contract Manufacturing Market Outlook

8.1. Market Size & Forecast
- 8.1.1. By Value
8.2. Market Share & Forecast
- 8.2.1. By Product
- 8.2.2. By Technology
- 8.2.3. By Application
- 8.2.4. By Country
8.3. Asia-Pacific: Country Analysis
- 8.3.1. China Biosimilar Contract Manufacturing Market Outlook
  - 8.3.1.1. Market Size & Forecast
    - 8.3.1.1.1. By Value
  - 8.3.1.2. Market Share & Forecast
    - 8.3.1.2.1. By Product
    - 8.3.1.2.2. By Technology
    - 8.3.1.2.3. By Application
- 8.3.2. India Biosimilar Contract Manufacturing Market Outlook
  - 8.3.2.1. Market Size & Forecast
    - 8.3.2.1.1. By Value
  - 8.3.2.2. Market Share & Forecast
    - 8.3.2.2.1. By Product
    - 8.3.2.2.2. By Technology
    - 8.3.2.2.3. By Application
- 8.3.3. Japan Biosimilar Contract Manufacturing Market Outlook
  - 8.3.3.1. Market Size & Forecast
    - 8.3.3.1.1. By Value
  - 8.3.3.2. Market Share & Forecast
    - 8.3.3.2.1. By Product
    - 8.3.3.2.2. By Technology
    - 8.3.3.2.3. By Application
- 8.3.4. South Korea Biosimilar Contract Manufacturing Market Outlook
  - 8.3.4.1. Market Size & Forecast
    - 8.3.4.1.1. By Value
  - 8.3.4.2. Market Share & Forecast
    - 8.3.4.2.1. By Product
    - 8.3.4.2.2. By Technology
    - 8.3.4.2.3. By Application
- 8.3.5. Australia Biosimilar Contract Manufacturing Market Outlook
  - 8.3.5.1. Market Size & Forecast
    - 8.3.5.1.1. By Value
  - 8.3.5.2. Market Share & Forecast
    - 8.3.5.2.1. By Product
    - 8.3.5.2.2. By Technology
    - 8.3.5.2.3. By Application

9. South America Biosimilar Contract Manufacturing Market Outlook

9.1. Market Size & Forecast
- 9.1.1. By Value
9.2. Market Share & Forecast
- 9.2.1. By Product
- 9.2.2. By Technology
- 9.2.3. By Application
- 9.2.4. By Country
9.3. South America: Country Analysis
- 9.3.1. Brazil Biosimilar Contract Manufacturing Market Outlook
  - 9.3.1.1. Market Size & Forecast
    - 9.3.1.1.1. By Value
  - 9.3.1.2. Market Share & Forecast
    - 9.3.1.2.1. By Product
    - 9.3.1.2.2. By Technology
    - 9.3.1.2.3. By Application
- 9.3.2. Argentina Biosimilar Contract Manufacturing Market Outlook
  - 9.3.2.1. Market Size & Forecast
    - 9.3.2.1.1. By Value
  - 9.3.2.2. Market Share & Forecast
    - 9.3.2.2.1. By Product
    - 9.3.2.2.2. By Technology
    - 9.3.2.2.3. By Application
- 9.3.3. Colombia Biosimilar Contract Manufacturing Market Outlook
  - 9.3.3.1. Market Size & Forecast
    - 9.3.3.1.1. By Value
  - 9.3.3.2. Market Share & Forecast
    - 9.3.3.2.1. By Product
    - 9.3.3.2.2. By Technology
    - 9.3.3.2.3. By Application

10. Middle East and Africa Biosimilar Contract Manufacturing Market Outlook

10.1. Market Size & Forecast
- 10.1.1. By Value
10.2. Market Share & Forecast
- 10.2.1. By Product
- 10.2.2. By Technology
- 10.2.3. By Application
- 10.2.4. By Country
10.3. MEA: Country Analysis
- 10.3.1. South Africa Biosimilar Contract Manufacturing Market Outlook
  - 10.3.1.1. Market Size & Forecast
    - 10.3.1.1.1. By Value
  - 10.3.1.2. Market Share & Forecast
    - 10.3.1.2.1. By Product
    - 10.3.1.2.2. By Technology
    - 10.3.1.2.3. By Application
- 10.3.2. Saudi Arabia Biosimilar Contract Manufacturing Market Outlook
  - 10.3.2.1. Market Size & Forecast
    - 10.3.2.1.1. By Value
  - 10.3.2.2. Market Share & Forecast
    - 10.3.2.2.1. By Product
    - 10.3.2.2.2. By Technology
    - 10.3.2.2.3. By Application
- 10.3.3. UAE Biosimilar Contract Manufacturing Market Outlook
  - 10.3.3.1. Market Size & Forecast
    - 10.3.3.1.1. By Value
  - 10.3.3.2. Market Share & Forecast
    - 10.3.3.2.1. By Product
    - 10.3.3.2.2. By Technology
    - 10.3.3.2.3. By Application

11. Market Dynamics

11.1. Drivers
11.2. Challenges

12. Market Trends & Developments

12.1. Merger & Acquisition (If Any)
12.2. Product Launches (If Any)
12.3. Recent Developments

13. Porters Five Forces Analysis

13.1. Competition in the Industry
13.2. Potential of New Entrants
13.3. Power of Suppliers
13.4. Power of Customers
13.5. Threat of Substitute Products/Services

14. Competitive Landscape

14.1. Catalent, Inc.
- 14.1.1. Business Overview
- 14.1.2. Company Snapshot
- 14.1.3. Products & Services
- 14.1.4. Financials (As Reported)
- 14.1.5. Recent Developments
- 14.1.6. Key Personnel Details
- 14.1.7. SWOT Analysis
14.2. Boehringer Ingelheim GmbH
14.3. Alcami Corporation, Inc.
14.4. Almac Group
14.5. Lonza Group AG
14.6. Biocon Limited
14.7. Avid Bioservice, Inc.
14.8. Rentschler Biopharma SE
14.9. Fujifilm Kyowa Kirin Biologics Co., Ltd.