ACE Inhibitors Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Type, By Drug, By Dosage Form, By Application, By End user, By Region and Competition, 2020-2030F

Description

The Global ACE Inhibitors Market, valued at USD 6.94 Billion in 2024, is projected to experience a CAGR of 5.75% to reach USD 9.71 Billion by 2030. Angiotensin-converting enzyme (ACE) inhibitors constitute a class of pharmaceutical agents primarily utilized to relax blood vessels and reduce blood pressure, thereby managing conditions such as hypertension, heart failure, and chronic kidney disease. The market for these inhibitors is principally driven by the rising global prevalence of cardiovascular diseases and hypertension, alongside an expanding aging population.

Market Overview
Forecast Period	2026-2030
Market Size 2024	USD 6.94 Billion
Market Size 2030	USD 9.71 Billion
CAGR 2025-2030	5.75%
Fastest Growing Segment	Oral Tablets
Largest Market	North America

Key Market Drivers

The increasing global burden of cardiovascular diseases represents a fundamental driver for the ACE inhibitors market. The widespread prevalence of conditions such as hypertension and heart failure necessitates effective and accessible therapeutic options. These illnesses not only reduce quality of life but also place substantial strain on healthcare systems worldwide. According to the "Global, regional, and national burden of cardiovascular diseases and risk factors in 204 countries and territories, 1990-2023" published in JACC, in September 2025, the number of prevalent cases of cardiovascular disease reached 626 million globally in 2023, underscoring the vast and growing patient population requiring management for these conditions. This elevated disease burden directly fuels the demand for ACE inhibitors, which are cornerstone treatments for various cardiovascular ailments, driving sustained market expansion.

Key Market Challenges

The potential for adverse effects associated with angiotensin-converting enzyme (ACE) inhibitors presents a significant impediment to market expansion. These side effects, including persistent cough, hyperkalemia, and rare angioedema, frequently lead to patient non-adherence or complete discontinuation of therapy. Such reactions directly diminish the patient base that continues to utilize ACE inhibitor treatments. According to research published in *Frontiers in Cardiovascular Medicine* in 2023, approximately 23.0% of patients prescribed ACE inhibitors were non-persistent with their treatment. This substantial rate of non-persistence, often influenced by the challenges of managing adverse drug reactions, directly limits the therapeutic lifespan of ACE inhibitors for individual patients.

Key Market Trends

The growing adoption of fixed-dose combination therapies represents a pivotal trend in the Global ACE Inhibitors Market. These single-pill combinations enhance patient adherence by simplifying complex treatment regimens, which is crucial for managing chronic conditions like hypertension and heart failure. Such formulations improve therapeutic outcomes by ensuring consistent medication intake. For instance, according to a study published in *J Clin Hypertens (Greenwich)* in August 2025, patients receiving angiotensin-converting enzyme inhibitor or angiotensin receptor blocker combination therapies exhibited the highest adherence rate at 79.18% in 2022-2023, compared to other antihypertensive drug classes. This improvement in adherence directly contributes to better disease control and sustained demand for ACE inhibitor-inclusive fixed-dose combinations.

Key Market Players

Pfizer Inc
Novartis AG
Johnson & Johnson
Merck KGaA
Sanofi S.A
Bayer AG
United Therapeutics Corporation
Teva Pharmaceutical Industry
Bristol-Myers Squibb
Takeda Pharmaceuticals Company

Report Scope:

In this report, the Global ACE Inhibitors Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

ACE Inhibitors Market, By Type:

Sulfhydryl-containing Agents
Dicarboxylate-containing Agents.
Phosphonate-containing Agents

ACE Inhibitors Market, By Drug:

Ramipril
Enalapril
Benazepril
Fosinopril
Captopril
Moexipril
Others

ACE Inhibitors Market, By Dosage Form:

Oral Tablets
Oral Solutions

ACE Inhibitors Market, By Application:

Heart Failure
Chronic Kidney Disease
Hypertension
Diabetes
Heart Attack
Others

ACE Inhibitors Market, By End user:

Hospitals
Online Drug Stores
Others

ACE Inhibitors Market, By Region:

North America
- United States
- Canada
- Mexico
Europe
- France
- United Kingdom
- Italy
- Germany
- Spain
Asia Pacific
- China
- India
- Japan
- Australia
- South Korea
South America
- Brazil
- Argentina
- Colombia
Middle East & Africa
- South Africa
- Saudi Arabia
- UAE

Competitive Landscape

Company Profiles: Detailed analysis of the major companies presents in the Global ACE Inhibitors Market.

Available Customizations:

Global ACE Inhibitors Market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

1. Product Overview

1.1. Market Definition
1.2. Scope of the Market
- 1.2.1. Markets Covered
- 1.2.2. Years Considered for Study
- 1.2.3. Key Market Segmentations

2. Research Methodology

2.1. Objective of the Study
2.2. Baseline Methodology
2.3. Key Industry Partners
2.4. Major Association and Secondary Sources
2.5. Forecasting Methodology
2.6. Data Triangulation & Validation
2.7. Assumptions and Limitations

3. Executive Summary

3.1. Overview of the Market
3.2. Overview of Key Market Segmentations
3.3. Overview of Key Market Players
3.4. Overview of Key Regions/Countries
3.5. Overview of Market Drivers, Challenges, Trends

4. Voice of Customer

5. Global ACE Inhibitors Market Outlook

5.1. Market Size & Forecast
- 5.1.1. By Value
5.2. Market Share & Forecast
- 5.2.1. By Type (Sulfhydryl-containing Agents, Dicarboxylate-containing Agents., Phosphonate-containing Agents)
- 5.2.2. By Drug (Ramipril, Enalapril, Benazepril, Fosinopril, Captopril, Moexipril, Others)
- 5.2.3. By Dosage Form (Oral Tablets, Oral Solutions)
- 5.2.4. By Application (Heart Failure, Chronic Kidney Disease, Hypertension, Diabetes, Heart Attack, Others)
- 5.2.5. By End user (Hospitals, Online Drug Stores, Others)
- 5.2.6. By Region
- 5.2.7. By Company (2024)
5.3. Market Map

6. North America ACE Inhibitors Market Outlook

6.1. Market Size & Forecast
- 6.1.1. By Value
6.2. Market Share & Forecast
- 6.2.1. By Type
- 6.2.2. By Drug
- 6.2.3. By Dosage Form
- 6.2.4. By Application
- 6.2.5. By End user
- 6.2.6. By Country
6.3. North America: Country Analysis
- 6.3.1. United States ACE Inhibitors Market Outlook
  - 6.3.1.1. Market Size & Forecast
    - 6.3.1.1.1. By Value
  - 6.3.1.2. Market Share & Forecast
    - 6.3.1.2.1. By Type
    - 6.3.1.2.2. By Drug
    - 6.3.1.2.3. By Dosage Form
    - 6.3.1.2.4. By Application
    - 6.3.1.2.5. By End user
- 6.3.2. Canada ACE Inhibitors Market Outlook
  - 6.3.2.1. Market Size & Forecast
    - 6.3.2.1.1. By Value
  - 6.3.2.2. Market Share & Forecast
    - 6.3.2.2.1. By Type
    - 6.3.2.2.2. By Drug
    - 6.3.2.2.3. By Dosage Form
    - 6.3.2.2.4. By Application
    - 6.3.2.2.5. By End user
- 6.3.3. Mexico ACE Inhibitors Market Outlook
  - 6.3.3.1. Market Size & Forecast
    - 6.3.3.1.1. By Value
  - 6.3.3.2. Market Share & Forecast
    - 6.3.3.2.1. By Type
    - 6.3.3.2.2. By Drug
    - 6.3.3.2.3. By Dosage Form
    - 6.3.3.2.4. By Application
    - 6.3.3.2.5. By End user

7. Europe ACE Inhibitors Market Outlook

7.1. Market Size & Forecast
- 7.1.1. By Value
7.2. Market Share & Forecast
- 7.2.1. By Type
- 7.2.2. By Drug
- 7.2.3. By Dosage Form
- 7.2.4. By Application
- 7.2.5. By End user
- 7.2.6. By Country
7.3. Europe: Country Analysis
- 7.3.1. Germany ACE Inhibitors Market Outlook
  - 7.3.1.1. Market Size & Forecast
    - 7.3.1.1.1. By Value
  - 7.3.1.2. Market Share & Forecast
    - 7.3.1.2.1. By Type
    - 7.3.1.2.2. By Drug
    - 7.3.1.2.3. By Dosage Form
    - 7.3.1.2.4. By Application
    - 7.3.1.2.5. By End user
- 7.3.2. France ACE Inhibitors Market Outlook
  - 7.3.2.1. Market Size & Forecast
    - 7.3.2.1.1. By Value
  - 7.3.2.2. Market Share & Forecast
    - 7.3.2.2.1. By Type
    - 7.3.2.2.2. By Drug
    - 7.3.2.2.3. By Dosage Form
    - 7.3.2.2.4. By Application
    - 7.3.2.2.5. By End user
- 7.3.3. United Kingdom ACE Inhibitors Market Outlook
  - 7.3.3.1. Market Size & Forecast
    - 7.3.3.1.1. By Value
  - 7.3.3.2. Market Share & Forecast
    - 7.3.3.2.1. By Type
    - 7.3.3.2.2. By Drug
    - 7.3.3.2.3. By Dosage Form
    - 7.3.3.2.4. By Application
    - 7.3.3.2.5. By End user
- 7.3.4. Italy ACE Inhibitors Market Outlook
  - 7.3.4.1. Market Size & Forecast
    - 7.3.4.1.1. By Value
  - 7.3.4.2. Market Share & Forecast
    - 7.3.4.2.1. By Type
    - 7.3.4.2.2. By Drug
    - 7.3.4.2.3. By Dosage Form
    - 7.3.4.2.4. By Application
    - 7.3.4.2.5. By End user
- 7.3.5. Spain ACE Inhibitors Market Outlook
  - 7.3.5.1. Market Size & Forecast
    - 7.3.5.1.1. By Value
  - 7.3.5.2. Market Share & Forecast
    - 7.3.5.2.1. By Type
    - 7.3.5.2.2. By Drug
    - 7.3.5.2.3. By Dosage Form
    - 7.3.5.2.4. By Application
    - 7.3.5.2.5. By End user

8. Asia Pacific ACE Inhibitors Market Outlook

8.1. Market Size & Forecast
- 8.1.1. By Value
8.2. Market Share & Forecast
- 8.2.1. By Type
- 8.2.2. By Drug
- 8.2.3. By Dosage Form
- 8.2.4. By Application
- 8.2.5. By End user
- 8.2.6. By Country
8.3. Asia Pacific: Country Analysis
- 8.3.1. China ACE Inhibitors Market Outlook
  - 8.3.1.1. Market Size & Forecast
    - 8.3.1.1.1. By Value
  - 8.3.1.2. Market Share & Forecast
    - 8.3.1.2.1. By Type
    - 8.3.1.2.2. By Drug
    - 8.3.1.2.3. By Dosage Form
    - 8.3.1.2.4. By Application
    - 8.3.1.2.5. By End user
- 8.3.2. India ACE Inhibitors Market Outlook
  - 8.3.2.1. Market Size & Forecast
    - 8.3.2.1.1. By Value
  - 8.3.2.2. Market Share & Forecast
    - 8.3.2.2.1. By Type
    - 8.3.2.2.2. By Drug
    - 8.3.2.2.3. By Dosage Form
    - 8.3.2.2.4. By Application
    - 8.3.2.2.5. By End user
- 8.3.3. Japan ACE Inhibitors Market Outlook
  - 8.3.3.1. Market Size & Forecast
    - 8.3.3.1.1. By Value
  - 8.3.3.2. Market Share & Forecast
    - 8.3.3.2.1. By Type
    - 8.3.3.2.2. By Drug
    - 8.3.3.2.3. By Dosage Form
    - 8.3.3.2.4. By Application
    - 8.3.3.2.5. By End user
- 8.3.4. South Korea ACE Inhibitors Market Outlook
  - 8.3.4.1. Market Size & Forecast
    - 8.3.4.1.1. By Value
  - 8.3.4.2. Market Share & Forecast
    - 8.3.4.2.1. By Type
    - 8.3.4.2.2. By Drug
    - 8.3.4.2.3. By Dosage Form
    - 8.3.4.2.4. By Application
    - 8.3.4.2.5. By End user
- 8.3.5. Australia ACE Inhibitors Market Outlook
  - 8.3.5.1. Market Size & Forecast
    - 8.3.5.1.1. By Value
  - 8.3.5.2. Market Share & Forecast
    - 8.3.5.2.1. By Type
    - 8.3.5.2.2. By Drug
    - 8.3.5.2.3. By Dosage Form
    - 8.3.5.2.4. By Application
    - 8.3.5.2.5. By End user

9. Middle East & Africa ACE Inhibitors Market Outlook

9.1. Market Size & Forecast
- 9.1.1. By Value
9.2. Market Share & Forecast
- 9.2.1. By Type
- 9.2.2. By Drug
- 9.2.3. By Dosage Form
- 9.2.4. By Application
- 9.2.5. By End user
- 9.2.6. By Country
9.3. Middle East & Africa: Country Analysis
- 9.3.1. Saudi Arabia ACE Inhibitors Market Outlook
  - 9.3.1.1. Market Size & Forecast
    - 9.3.1.1.1. By Value
  - 9.3.1.2. Market Share & Forecast
    - 9.3.1.2.1. By Type
    - 9.3.1.2.2. By Drug
    - 9.3.1.2.3. By Dosage Form
    - 9.3.1.2.4. By Application
    - 9.3.1.2.5. By End user
- 9.3.2. UAE ACE Inhibitors Market Outlook
  - 9.3.2.1. Market Size & Forecast
    - 9.3.2.1.1. By Value
  - 9.3.2.2. Market Share & Forecast
    - 9.3.2.2.1. By Type
    - 9.3.2.2.2. By Drug
    - 9.3.2.2.3. By Dosage Form
    - 9.3.2.2.4. By Application
    - 9.3.2.2.5. By End user
- 9.3.3. South Africa ACE Inhibitors Market Outlook
  - 9.3.3.1. Market Size & Forecast
    - 9.3.3.1.1. By Value
  - 9.3.3.2. Market Share & Forecast
    - 9.3.3.2.1. By Type
    - 9.3.3.2.2. By Drug
    - 9.3.3.2.3. By Dosage Form
    - 9.3.3.2.4. By Application
    - 9.3.3.2.5. By End user

10. South America ACE Inhibitors Market Outlook

10.1. Market Size & Forecast
- 10.1.1. By Value
10.2. Market Share & Forecast
- 10.2.1. By Type
- 10.2.2. By Drug
- 10.2.3. By Dosage Form
- 10.2.4. By Application
- 10.2.5. By End user
- 10.2.6. By Country
10.3. South America: Country Analysis
- 10.3.1. Brazil ACE Inhibitors Market Outlook
  - 10.3.1.1. Market Size & Forecast
    - 10.3.1.1.1. By Value
  - 10.3.1.2. Market Share & Forecast
    - 10.3.1.2.1. By Type
    - 10.3.1.2.2. By Drug
    - 10.3.1.2.3. By Dosage Form
    - 10.3.1.2.4. By Application
    - 10.3.1.2.5. By End user
- 10.3.2. Colombia ACE Inhibitors Market Outlook
  - 10.3.2.1. Market Size & Forecast
    - 10.3.2.1.1. By Value
  - 10.3.2.2. Market Share & Forecast
    - 10.3.2.2.1. By Type
    - 10.3.2.2.2. By Drug
    - 10.3.2.2.3. By Dosage Form
    - 10.3.2.2.4. By Application
    - 10.3.2.2.5. By End user
- 10.3.3. Argentina ACE Inhibitors Market Outlook
  - 10.3.3.1. Market Size & Forecast
    - 10.3.3.1.1. By Value
  - 10.3.3.2. Market Share & Forecast
    - 10.3.3.2.1. By Type
    - 10.3.3.2.2. By Drug
    - 10.3.3.2.3. By Dosage Form
    - 10.3.3.2.4. By Application
    - 10.3.3.2.5. By End user

11. Market Dynamics

11.1. Drivers
11.2. Challenges

12. Market Trends & Developments

12.1. Merger & Acquisition (If Any)
12.2. Product Launches (If Any)
12.3. Recent Developments

13. Global ACE Inhibitors Market: SWOT Analysis

14. Porter's Five Forces Analysis

14.1. Competition in the Industry
14.2. Potential of New Entrants
14.3. Power of Suppliers
14.4. Power of Customers
14.5. Threat of Substitute Products

15. Competitive Landscape

15.1. Pfizer Inc
- 15.1.1. Business Overview
- 15.1.2. Products & Services
- 15.1.3. Recent Developments
- 15.1.4. Key Personnel
- 15.1.5. SWOT Analysis
15.2. Novartis AG
15.3. Johnson & Johnson
15.4. Merck KGaA
15.5. Sanofi S.A
15.6. Bayer AG
15.7. United Therapeutics Corporation
15.8. Teva Pharmaceutical Industry
15.9. Bristol-Myers Squibb
15.10. Takeda Pharmaceuticals Company