Human Insulin Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Indication, By Brand, By Route of Administration, By Type, By Onset Time, By Products, By Region & Competition, 2021-2031F

Description

The Global Human Insulin Market is projected to expand from USD 24.81 Billion in 2025 to USD 38.31 Billion by 2031, reflecting a compound annual growth rate of 7.51%. This sector covers the commercial environment for biosynthetic peptide hormones that are structurally identical to endogenous insulin, serving as a critical regulation method for blood glucose in patients with diabetes mellitus. The market's upward trajectory is largely fueled by the intensifying global prevalence of diabetes, exacerbated by urbanization, aging populations, and increasing obesity rates which demand consistent therapeutic management. As reported by the International Diabetes Federation in 2024, roughly 589 million adults worldwide were living with diabetes, highlighting an immense patient population requiring effective medical solutions.

Market Overview
Forecast Period	2027-2031
Market Size 2025	USD 24.81 Billion
Market Size 2031	USD 38.31 Billion
CAGR 2026-2031	7.51%
Fastest Growing Segment	Biosimilar
Largest Market	North America

A significant challenge hindering market expansion is the substantial cost associated with manufacturing and distribution, which restricts product affordability in developing nations. These financial obstacles frequently compromise patient adherence and limit market penetration in the very regions experiencing the most rapid rise in disease prevalence. Consequently, strict pricing constraints combined with insufficient reimbursement structures in these areas create a major bottleneck for widespread insulin adoption, thereby curbing potential revenue growth.

Market Driver

Technological advancements in insulin delivery systems are transforming patient care by transitioning preferences from conventional vials and syringes to automated, minimally invasive devices. Innovations including smart insulin pens, tubeless pumps, and closed-loop systems linked with continuous glucose monitors significantly improve glycemic control and treatment adherence. This evolution is driven by the growing demand for advanced platforms that provide precise dosing while minimizing lifestyle disruptions. For example, Insulet Corporation reported in its Third Quarter 2024 Financial Results in November 2024 that revenue for its Omnipod insulin management system rose by approximately 26% year-over-year, supported by robust adoption in both type 1 and type 2 diabetes sectors, demonstrating how these technologies fuel market growth by addressing therapeutic needs.

Simultaneously, the rising adoption of cost-effective biosimilars is altering the competitive landscape by removing economic barriers to access. As patents for major insulin analogs expire, the launch of high-quality biosimilar alternatives provides significant savings for patients and healthcare systems, especially in emerging markets where affordability is paramount. This trend accelerates volume uptake and broadens the treated patient base, as evidenced by Biocon Limited's October 2024 Consolidated Financial Results for Q2 FY25, which showed a 19% year-over-year revenue increase in its biosimilars business on a like-for-like basis. Furthermore, with the International Diabetes Federation estimating global diabetes-related health expenditure to exceed USD 1 trillion in 2024, the urgent need for cost-efficient solutions continues to drive market expansion and sustainable healthcare spending.

Market Challenge

The substantial expense associated with manufacturing and distribution constitutes a major structural impediment to the growth of the Global Human Insulin Market, especially within developing economies. The production of biosynthetic peptide hormones necessitates rigorous quality control and complex, capital-intensive biotechnology facilities, establishing a high baseline cost for the finished product. Additionally, the logistical requirement to maintain a strict cold chain during distribution imposes significant overhead, further increasing the price for end users. In areas with lower average incomes and limited healthcare infrastructure, these cumulative costs make the therapy economically out of reach for a vast segment of the population, effectively limiting market penetration.

This economic disparity severely constrains market potential because the regions with the highest demand growth are often the most financially restricted. According to the International Diabetes Federation, more than 75 percent of adults with diabetes resided in low- and middle-income countries in 2024. This statistic highlights the scale of the difficulty, as the overwhelming majority of the potential patient pool lives in areas where current pricing structures are prohibitive. As a result, the market encounters a significant bottleneck where revenue growth is suppressed by the inability of the primary growth demographic to afford essential treatment.

Market Trends

The introduction of once-weekly basal insulin formulations is fundamentally shifting the treatment paradigm by alleviating the burden associated with daily injection schedules. Pharmaceutical developers are focusing on ultra-long-acting analogs capable of maintaining stable glycemic control for seven days, aiming to reduce injection fatigue and enhance long-term adherence among patients with type 2 diabetes. This innovation addresses lifestyle constraints through chemical structural advancements rather than just device improvements. For instance, Eli Lilly and Company reported in September 2024 from the QWINT-2 phase 3 trial that their once-weekly insulin efsitora alfa achieved non-inferiority to daily insulin degludec, lowering A1C levels by 1.34% compared to 1.26% in insulin-naive adults.

In parallel, the development of non-invasive and oral insulin delivery systems continues to draw substantial investment as companies seek to eliminate the need for subcutaneous administration. This trend involves persistent clinical research into encapsulated oral formulations engineered to survive gastric degradation, providing a needle-free option that could significantly broaden early insulin acceptance. Despite past clinical challenges, pursuit of this technology remains vigorous due to its potential to improve patient convenience and overcome psychological barriers to injectable therapies. Highlighting this ongoing effort, Oramed Pharmaceuticals announced in February 2024 its plans to restart a Phase 3 trial for its oral insulin candidate, ORMD-0801, targeting a specific patient subpopulation that showed significant responsiveness in earlier data analyses.

Key Market Players

Novo Nordisk A/S
Eli Lilly and Company
Sanofi S.A.
Biocon Limited
Wockhardt Limited
Julphar
Tonghua Dongbao Pharmaceutical Co., Ltd.
B. Braun Melsungen AG
Pfizer Inc.
Ypsomed AG

Report Scope

In this report, the Global Human Insulin Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

Human Insulin Market, By Indication

Type I Diabetes
Type II Diabetes

Human Insulin Market, By Brand

Lantus
Humulin R
Novolin R
Humulin N
Exubera
Afrezza
Novolin N

Human Insulin Market, By Route of Administration

Subcutaneous
Transdermal
Nasal
Intravenous
Oral
Others

Human Insulin Market, By Type

Basal
Bolus
Pre-mixed
Biosimilar
Traditional

Human Insulin Market, By Onset Time

Rapid acting
Short-acting
Intermediate acting
Long acting
Pre-Mixed
Inhaled
Ultra-long Acting

Human Insulin Market, By Products

Insulin Pens
Insulin Pumps
Infusion System
Injections

Human Insulin Market, By Region

North America
- United States
- Canada
- Mexico
Europe
- France
- United Kingdom
- Italy
- Germany
- Spain
Asia Pacific
- China
- India
- Japan
- Australia
- South Korea
South America
- Brazil
- Argentina
- Colombia
Middle East & Africa
- South Africa
- Saudi Arabia
- UAE

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the Global Human Insulin Market.

Available Customizations:

Global Human Insulin Market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

1. Product Overview

1.1. Market Definition
1.2. Scope of the Market
- 1.2.1. Markets Covered
- 1.2.2. Years Considered for Study
- 1.2.3. Key Market Segmentations

2. Research Methodology

2.1. Objective of the Study
2.2. Baseline Methodology
2.3. Key Industry Partners
2.4. Major Association and Secondary Sources
2.5. Forecasting Methodology
2.6. Data Triangulation & Validation
2.7. Assumptions and Limitations

3. Executive Summary

3.1. Overview of the Market
3.2. Overview of Key Market Segmentations
3.3. Overview of Key Market Players
3.4. Overview of Key Regions/Countries
3.5. Overview of Market Drivers, Challenges, Trends

4. Voice of Customer

5. Global Human Insulin Market Outlook

5.1. Market Size & Forecast
- 5.1.1. By Value
5.2. Market Share & Forecast
- 5.2.1. By Indication (Type I Diabetes, Type II Diabetes)
- 5.2.2. By Brand (Lantus, Humulin R, Novolin R, Humulin N, Exubera, Afrezza, Novolin N)
- 5.2.3. By Route of Administration (Subcutaneous, Transdermal, Nasal, Intravenous, Oral, Others)
- 5.2.4. By Type (Basal, Bolus, Pre-mixed, Biosimilar, Traditional)
- 5.2.5. By Onset Time (Rapid acting, Short-acting, Intermediate acting, Long acting, Pre-Mixed, Inhaled, Ultra-long Acting)
- 5.2.6. By Products (Insulin Pens, Insulin Pumps, Infusion System, Injections)
- 5.2.7. By Region
- 5.2.8. By Company (2025)
5.3. Market Map

6. North America Human Insulin Market Outlook

6.1. Market Size & Forecast
- 6.1.1. By Value
6.2. Market Share & Forecast
- 6.2.1. By Indication
- 6.2.2. By Brand
- 6.2.3. By Route of Administration
- 6.2.4. By Type
- 6.2.5. By Onset Time
- 6.2.6. By Products
- 6.2.7. By Country
6.3. North America: Country Analysis
- 6.3.1. United States Human Insulin Market Outlook
  - 6.3.1.1. Market Size & Forecast
    - 6.3.1.1.1. By Value
  - 6.3.1.2. Market Share & Forecast
    - 6.3.1.2.1. By Indication
    - 6.3.1.2.2. By Brand
    - 6.3.1.2.3. By Route of Administration
    - 6.3.1.2.4. By Type
    - 6.3.1.2.5. By Onset Time
    - 6.3.1.2.6. By Products
- 6.3.2. Canada Human Insulin Market Outlook
  - 6.3.2.1. Market Size & Forecast
    - 6.3.2.1.1. By Value
  - 6.3.2.2. Market Share & Forecast
    - 6.3.2.2.1. By Indication
    - 6.3.2.2.2. By Brand
    - 6.3.2.2.3. By Route of Administration
    - 6.3.2.2.4. By Type
    - 6.3.2.2.5. By Onset Time
    - 6.3.2.2.6. By Products
- 6.3.3. Mexico Human Insulin Market Outlook
  - 6.3.3.1. Market Size & Forecast
    - 6.3.3.1.1. By Value
  - 6.3.3.2. Market Share & Forecast
    - 6.3.3.2.1. By Indication
    - 6.3.3.2.2. By Brand
    - 6.3.3.2.3. By Route of Administration
    - 6.3.3.2.4. By Type
    - 6.3.3.2.5. By Onset Time
    - 6.3.3.2.6. By Products

7. Europe Human Insulin Market Outlook

7.1. Market Size & Forecast
- 7.1.1. By Value
7.2. Market Share & Forecast
- 7.2.1. By Indication
- 7.2.2. By Brand
- 7.2.3. By Route of Administration
- 7.2.4. By Type
- 7.2.5. By Onset Time
- 7.2.6. By Products
- 7.2.7. By Country
7.3. Europe: Country Analysis
- 7.3.1. Germany Human Insulin Market Outlook
  - 7.3.1.1. Market Size & Forecast
    - 7.3.1.1.1. By Value
  - 7.3.1.2. Market Share & Forecast
    - 7.3.1.2.1. By Indication
    - 7.3.1.2.2. By Brand
    - 7.3.1.2.3. By Route of Administration
    - 7.3.1.2.4. By Type
    - 7.3.1.2.5. By Onset Time
    - 7.3.1.2.6. By Products
- 7.3.2. France Human Insulin Market Outlook
  - 7.3.2.1. Market Size & Forecast
    - 7.3.2.1.1. By Value
  - 7.3.2.2. Market Share & Forecast
    - 7.3.2.2.1. By Indication
    - 7.3.2.2.2. By Brand
    - 7.3.2.2.3. By Route of Administration
    - 7.3.2.2.4. By Type
    - 7.3.2.2.5. By Onset Time
    - 7.3.2.2.6. By Products
- 7.3.3. United Kingdom Human Insulin Market Outlook
  - 7.3.3.1. Market Size & Forecast
    - 7.3.3.1.1. By Value
  - 7.3.3.2. Market Share & Forecast
    - 7.3.3.2.1. By Indication
    - 7.3.3.2.2. By Brand
    - 7.3.3.2.3. By Route of Administration
    - 7.3.3.2.4. By Type
    - 7.3.3.2.5. By Onset Time
    - 7.3.3.2.6. By Products
- 7.3.4. Italy Human Insulin Market Outlook
  - 7.3.4.1. Market Size & Forecast
    - 7.3.4.1.1. By Value
  - 7.3.4.2. Market Share & Forecast
    - 7.3.4.2.1. By Indication
    - 7.3.4.2.2. By Brand
    - 7.3.4.2.3. By Route of Administration
    - 7.3.4.2.4. By Type
    - 7.3.4.2.5. By Onset Time
    - 7.3.4.2.6. By Products
- 7.3.5. Spain Human Insulin Market Outlook
  - 7.3.5.1. Market Size & Forecast
    - 7.3.5.1.1. By Value
  - 7.3.5.2. Market Share & Forecast
    - 7.3.5.2.1. By Indication
    - 7.3.5.2.2. By Brand
    - 7.3.5.2.3. By Route of Administration
    - 7.3.5.2.4. By Type
    - 7.3.5.2.5. By Onset Time
    - 7.3.5.2.6. By Products

8. Asia Pacific Human Insulin Market Outlook

8.1. Market Size & Forecast
- 8.1.1. By Value
8.2. Market Share & Forecast
- 8.2.1. By Indication
- 8.2.2. By Brand
- 8.2.3. By Route of Administration
- 8.2.4. By Type
- 8.2.5. By Onset Time
- 8.2.6. By Products
- 8.2.7. By Country
8.3. Asia Pacific: Country Analysis
- 8.3.1. China Human Insulin Market Outlook
  - 8.3.1.1. Market Size & Forecast
    - 8.3.1.1.1. By Value
  - 8.3.1.2. Market Share & Forecast
    - 8.3.1.2.1. By Indication
    - 8.3.1.2.2. By Brand
    - 8.3.1.2.3. By Route of Administration
    - 8.3.1.2.4. By Type
    - 8.3.1.2.5. By Onset Time
    - 8.3.1.2.6. By Products
- 8.3.2. India Human Insulin Market Outlook
  - 8.3.2.1. Market Size & Forecast
    - 8.3.2.1.1. By Value
  - 8.3.2.2. Market Share & Forecast
    - 8.3.2.2.1. By Indication
    - 8.3.2.2.2. By Brand
    - 8.3.2.2.3. By Route of Administration
    - 8.3.2.2.4. By Type
    - 8.3.2.2.5. By Onset Time
    - 8.3.2.2.6. By Products
- 8.3.3. Japan Human Insulin Market Outlook
  - 8.3.3.1. Market Size & Forecast
    - 8.3.3.1.1. By Value
  - 8.3.3.2. Market Share & Forecast
    - 8.3.3.2.1. By Indication
    - 8.3.3.2.2. By Brand
    - 8.3.3.2.3. By Route of Administration
    - 8.3.3.2.4. By Type
    - 8.3.3.2.5. By Onset Time
    - 8.3.3.2.6. By Products
- 8.3.4. South Korea Human Insulin Market Outlook
  - 8.3.4.1. Market Size & Forecast
    - 8.3.4.1.1. By Value
  - 8.3.4.2. Market Share & Forecast
    - 8.3.4.2.1. By Indication
    - 8.3.4.2.2. By Brand
    - 8.3.4.2.3. By Route of Administration
    - 8.3.4.2.4. By Type
    - 8.3.4.2.5. By Onset Time
    - 8.3.4.2.6. By Products
- 8.3.5. Australia Human Insulin Market Outlook
  - 8.3.5.1. Market Size & Forecast
    - 8.3.5.1.1. By Value
  - 8.3.5.2. Market Share & Forecast
    - 8.3.5.2.1. By Indication
    - 8.3.5.2.2. By Brand
    - 8.3.5.2.3. By Route of Administration
    - 8.3.5.2.4. By Type
    - 8.3.5.2.5. By Onset Time
    - 8.3.5.2.6. By Products

9. Middle East & Africa Human Insulin Market Outlook

9.1. Market Size & Forecast
- 9.1.1. By Value
9.2. Market Share & Forecast
- 9.2.1. By Indication
- 9.2.2. By Brand
- 9.2.3. By Route of Administration
- 9.2.4. By Type
- 9.2.5. By Onset Time
- 9.2.6. By Products
- 9.2.7. By Country
9.3. Middle East & Africa: Country Analysis
- 9.3.1. Saudi Arabia Human Insulin Market Outlook
  - 9.3.1.1. Market Size & Forecast
    - 9.3.1.1.1. By Value
  - 9.3.1.2. Market Share & Forecast
    - 9.3.1.2.1. By Indication
    - 9.3.1.2.2. By Brand
    - 9.3.1.2.3. By Route of Administration
    - 9.3.1.2.4. By Type
    - 9.3.1.2.5. By Onset Time
    - 9.3.1.2.6. By Products
- 9.3.2. UAE Human Insulin Market Outlook
  - 9.3.2.1. Market Size & Forecast
    - 9.3.2.1.1. By Value
  - 9.3.2.2. Market Share & Forecast
    - 9.3.2.2.1. By Indication
    - 9.3.2.2.2. By Brand
    - 9.3.2.2.3. By Route of Administration
    - 9.3.2.2.4. By Type
    - 9.3.2.2.5. By Onset Time
    - 9.3.2.2.6. By Products
- 9.3.3. South Africa Human Insulin Market Outlook
  - 9.3.3.1. Market Size & Forecast
    - 9.3.3.1.1. By Value
  - 9.3.3.2. Market Share & Forecast
    - 9.3.3.2.1. By Indication
    - 9.3.3.2.2. By Brand
    - 9.3.3.2.3. By Route of Administration
    - 9.3.3.2.4. By Type
    - 9.3.3.2.5. By Onset Time
    - 9.3.3.2.6. By Products

10. South America Human Insulin Market Outlook

10.1. Market Size & Forecast
- 10.1.1. By Value
10.2. Market Share & Forecast
- 10.2.1. By Indication
- 10.2.2. By Brand
- 10.2.3. By Route of Administration
- 10.2.4. By Type
- 10.2.5. By Onset Time
- 10.2.6. By Products
- 10.2.7. By Country
10.3. South America: Country Analysis
- 10.3.1. Brazil Human Insulin Market Outlook
  - 10.3.1.1. Market Size & Forecast
    - 10.3.1.1.1. By Value
  - 10.3.1.2. Market Share & Forecast
    - 10.3.1.2.1. By Indication
    - 10.3.1.2.2. By Brand
    - 10.3.1.2.3. By Route of Administration
    - 10.3.1.2.4. By Type
    - 10.3.1.2.5. By Onset Time
    - 10.3.1.2.6. By Products
- 10.3.2. Colombia Human Insulin Market Outlook
  - 10.3.2.1. Market Size & Forecast
    - 10.3.2.1.1. By Value
  - 10.3.2.2. Market Share & Forecast
    - 10.3.2.2.1. By Indication
    - 10.3.2.2.2. By Brand
    - 10.3.2.2.3. By Route of Administration
    - 10.3.2.2.4. By Type
    - 10.3.2.2.5. By Onset Time
    - 10.3.2.2.6. By Products
- 10.3.3. Argentina Human Insulin Market Outlook
  - 10.3.3.1. Market Size & Forecast
    - 10.3.3.1.1. By Value
  - 10.3.3.2. Market Share & Forecast
    - 10.3.3.2.1. By Indication
    - 10.3.3.2.2. By Brand
    - 10.3.3.2.3. By Route of Administration
    - 10.3.3.2.4. By Type
    - 10.3.3.2.5. By Onset Time
    - 10.3.3.2.6. By Products

11. Market Dynamics

11.1. Drivers
11.2. Challenges

12. Market Trends & Developments

12.1. Merger & Acquisition (If Any)
12.2. Product Launches (If Any)
12.3. Recent Developments

13. Global Human Insulin Market: SWOT Analysis

14. Porter's Five Forces Analysis

14.1. Competition in the Industry
14.2. Potential of New Entrants
14.3. Power of Suppliers
14.4. Power of Customers
14.5. Threat of Substitute Products

15. Competitive Landscape

15.1. Novo Nordisk A/S
- 15.1.1. Business Overview
- 15.1.2. Products & Services
- 15.1.3. Recent Developments
- 15.1.4. Key Personnel
- 15.1.5. SWOT Analysis
15.2. Eli Lilly and Company
15.3. Sanofi S.A.
15.4. Biocon Limited
15.5. Wockhardt Limited
15.6. Julphar
15.7. Tonghua Dongbao Pharmaceutical Co., Ltd.
15.8. B. Braun Melsungen AG
15.9. Pfizer Inc.
15.10. Ypsomed AG