Dental Bone Graft Substitute Market - Global Industry Size, Share, Trends, Opportunity, and Forecast Segmented By Type, By Material, By Mechanism, By Product, By Application, By End User, By Region & Competition, 2021-2031F

Description

The Global Dental Bone Graft Substitute Market is projected to experience substantial growth, expanding from USD 908.28 Million in 2025 to USD 1416.68 Million by 2031 at a CAGR of 7.69%. These specialized biomaterials function as scaffolds to facilitate natural bone regeneration, playing a critical role in restorative treatments such as dental implant placement and periodontal therapy to correct bone defects. This expansion is primarily driven by the rising global demand for tooth replacement solutions and the growing prevalence of periodontal diseases in an aging population. Underscoring the scale of this clinical need, the European Federation of Periodontology reported in 2024 that the treatment of preventable oral conditions, including periodontitis and caries, accounted for roughly 5% of global healthcare expenditures, highlighting the significant burden requiring effective restorative interventions.

Market Overview
Forecast Period	2027-2031
Market Size 2025	USD 908.28 Million
Market Size 2031	USD 1416.68 Million
CAGR 2026-2031	7.69%
Fastest Growing Segment	Allograft
Largest Market	Europe

However, despite strong demand, the market faces a major restraint due to the high cost of regenerative procedures and the frequent lack of comprehensive reimbursement policies. In many regions, insurance providers do not fully cover these advanced treatments, leading to substantial out-of-pocket expenses that limit patient access, particularly in emerging economies. As a result, affordability issues prevent the widespread adoption of premium bone graft substitutes among lower-income demographics. This economic barrier hampers market potential in cost-sensitive areas, restricting the reach of advanced grafting therapies to primarily affluent patient segments.

Market Driver

A primary catalyst for the bone graft substitute market is the surging global demand for dental implant procedures, which has established a direct dependency between implant adoption and the need for bone regeneration materials. Since adequate bone volume is essential for implant stability, the prevalence of ridge deficiencies necessitates the concurrent use of bone grafts, making them integral to modern restorative dentistry. This trend is reflected in the financial success of key industry players; for instance, Straumann Group's 'Full Year 2024 Annual Report', released in February 2025, reported revenues of CHF 2.5 billion with 13.7% organic growth, driven largely by its robust implantology business. Furthermore, the American Dental Association noted in 2025 that U.S. consumer dental spending rose by 4% through August, indicating sustained patient investment in restorative oral healthcare.

The second critical driver is the expanding geriatric population and the associated rise in edentulism and severe periodontal conditions. Aging naturally leads to alveolar bone resorption and increased susceptibility to oral diseases that compromise jaw structure, thereby fueling the necessity for reconstructive bone therapy. Severe periodontitis remains a pervasive global health challenge; the World Health Organization's 'Oral Health' fact sheet from March 2025 estimated that over 1 billion cases of severe periodontal disease exist worldwide. This vast scale of pathology highlights the urgent need for regenerative interventions, ensuring that as the global population ages and faces complex oral health issues, the reliance on effective bone graft substitutes for rehabilitation will continue to intensify.

Market Challenge

The most significant impediment to the growth of the Global Dental Bone Graft Substitute Market is the prohibitive cost of regenerative procedures coupled with the absence of adequate reimbursement frameworks. Many insurance providers classify advanced bone grafting as an elective or cosmetic service rather than a medical necessity, forcing patients to shoulder significant out-of-pocket costs. This financial burden severely restricts market penetration, as a large portion of the patient population is compelled to choose less expensive, non-restorative alternatives or delay treatment indefinitely. Consequently, the adoption of bone graft substitutes is often limited to wealthier demographics, preventing the market from realizing its full volume potential in emerging and cost-sensitive economies.

This economic barrier leads to a quantifiable decrease in patient engagement with professional dental services, creating a bottleneck for specialized care. According to the American Dental Association in 2024, dental care presented the highest cost barriers compared to other health services, contributing to a utilization rate where only 40% of working-age adults visited a dentist. This statistic underscores a direct link between high costs and low service uptake; when patients are unable to afford basic access to dental professionals due to financial constraints, the downstream demand for sophisticated, high-cost procedures like bone grafting is inevitably throttled, thereby stalling overall market expansion.

Market Trends

A major trend reshaping the market is the convergence of digital workflow and guided bone regeneration technologies, which are enhancing clinical precision and outcomes. By integrating cone-beam computed tomography (CBCT) and intraoral scanning, clinicians can leverage software-driven tools to calculate exact bone volume requirements and fabricate custom surgical guides, significantly improving the predictability of complex ridge augmentations. The rapid adoption of this technology is evidenced by industry performance; Straumann Group's 'Annual Report 2024', published in February 2025, highlighted double-digit revenue growth in its digital solutions business globally. This expansion confirms that digitized interconnectivity is becoming a standard component of routine implant and regenerative procedures.

Concurrently, there is an accelerated shift toward the use of synthetic and xenograft materials, which are displacing traditional autogenous bone harvesting as the preferred standard for augmentation. This transition is driven by the clinical goal of minimizing patient morbidity associated with secondary surgical sites and the availability of high-quality, off-the-shelf biomaterials that offer effective osteoconductive scaffolds. The commercial impact of this preference is clear in financial results; Henry Schein's 'Fourth Quarter and Full Year 2024 Financial Results' from February 2025 reported that their Global Specialty Products segment, encompassing biomaterials, achieved sales of $1.4 billion-an 8.7% increase from the prior year. This growth highlights the sustained momentum in the consumption of these convenient reconstructive materials over autografts.

Key Market Players

Dentsply Sirona Inc.
ZimVie Inc.
Medtronic plc
Institut Straumann AG
Geistlich Pharma AG
BioHorizons Inc.
NovaBone Products, LLC
Botiss Biomaterials GmbH
LifeNet Health, Inc.
RTI Surgical Holdings, Inc.

Report Scope

In this report, the Global Dental Bone Graft Substitute Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

Dental Bone Graft Substitute Market, By Type

Allograft
Xenograft
Autograft
Synthetic Bone Graft
Others

Dental Bone Graft Substitute Market, By Material

Human Cell Source
Collagen
Animal Source
Others

Dental Bone Graft Substitute Market, By Mechanism

Osteoconduction
Osteoinduction
Osteopromotion
Osteogenesis

Dental Bone Graft Substitute Market, By Product

Bio OSS
Grafton
Osteograf

Dental Bone Graft Substitute Market, By Application

Socket Preservation
Ridge Augmentation
Periodontal Defect Regeneration
Implant Bone Regeneration
Sinus Lift

Dental Bone Graft Substitute Market, By End User

Hospitals & Clinics
Dental Laboratories
Others

Dental Bone Graft Substitute Market, By Region

North America
- United States
- Canada
- Mexico
Europe
- France
- United Kingdom
- Italy
- Germany
- Spain
Asia Pacific
- China
- India
- Japan
- Australia
- South Korea
South America
- Brazil
- Argentina
- Colombia
Middle East & Africa
- South Africa
- Saudi Arabia
- UAE

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the Global Dental Bone Graft Substitute Market.

Available Customizations:

Global Dental Bone Graft Substitute Market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

1. Product Overview

1.1. Market Definition
1.2. Scope of the Market
- 1.2.1. Markets Covered
- 1.2.2. Years Considered for Study
- 1.2.3. Key Market Segmentations

2. Research Methodology

2.1. Objective of the Study
2.2. Baseline Methodology
2.3. Key Industry Partners
2.4. Major Association and Secondary Sources
2.5. Forecasting Methodology
2.6. Data Triangulation & Validation
2.7. Assumptions and Limitations

3. Executive Summary

3.1. Overview of the Market
3.2. Overview of Key Market Segmentations
3.3. Overview of Key Market Players
3.4. Overview of Key Regions/Countries
3.5. Overview of Market Drivers, Challenges, Trends

4. Voice of Customer

5. Global Dental Bone Graft Substitute Market Outlook

5.1. Market Size & Forecast
- 5.1.1. By Value
5.2. Market Share & Forecast
- 5.2.1. By Type (Allograft, Xenograft, Autograft, Synthetic Bone Graft, Others)
- 5.2.2. By Material (Human Cell Source, Collagen, Animal Source, Others)
- 5.2.3. By Mechanism (Osteoconduction, Osteoinduction, Osteopromotion, Osteogenesis)
- 5.2.4. By Product (Bio OSS, Grafton, Osteograf)
- 5.2.5. By Application (Socket Preservation, Ridge Augmentation, Periodontal Defect Regeneration, Implant Bone Regeneration, Sinus Lift)
- 5.2.6. By End User (Hospitals & Clinics, Dental Laboratories, Others)
- 5.2.7. By Region
- 5.2.8. By Company (2025)
5.3. Market Map

6. North America Dental Bone Graft Substitute Market Outlook

6.1. Market Size & Forecast
- 6.1.1. By Value
6.2. Market Share & Forecast
- 6.2.1. By Type
- 6.2.2. By Material
- 6.2.3. By Mechanism
- 6.2.4. By Product
- 6.2.5. By Application
- 6.2.6. By End User
- 6.2.7. By Country
6.3. North America: Country Analysis
- 6.3.1. United States Dental Bone Graft Substitute Market Outlook
  - 6.3.1.1. Market Size & Forecast
    - 6.3.1.1.1. By Value
  - 6.3.1.2. Market Share & Forecast
    - 6.3.1.2.1. By Type
    - 6.3.1.2.2. By Material
    - 6.3.1.2.3. By Mechanism
    - 6.3.1.2.4. By Product
    - 6.3.1.2.5. By Application
    - 6.3.1.2.6. By End User
- 6.3.2. Canada Dental Bone Graft Substitute Market Outlook
  - 6.3.2.1. Market Size & Forecast
    - 6.3.2.1.1. By Value
  - 6.3.2.2. Market Share & Forecast
    - 6.3.2.2.1. By Type
    - 6.3.2.2.2. By Material
    - 6.3.2.2.3. By Mechanism
    - 6.3.2.2.4. By Product
    - 6.3.2.2.5. By Application
    - 6.3.2.2.6. By End User
- 6.3.3. Mexico Dental Bone Graft Substitute Market Outlook
  - 6.3.3.1. Market Size & Forecast
    - 6.3.3.1.1. By Value
  - 6.3.3.2. Market Share & Forecast
    - 6.3.3.2.1. By Type
    - 6.3.3.2.2. By Material
    - 6.3.3.2.3. By Mechanism
    - 6.3.3.2.4. By Product
    - 6.3.3.2.5. By Application
    - 6.3.3.2.6. By End User

7. Europe Dental Bone Graft Substitute Market Outlook

7.1. Market Size & Forecast
- 7.1.1. By Value
7.2. Market Share & Forecast
- 7.2.1. By Type
- 7.2.2. By Material
- 7.2.3. By Mechanism
- 7.2.4. By Product
- 7.2.5. By Application
- 7.2.6. By End User
- 7.2.7. By Country
7.3. Europe: Country Analysis
- 7.3.1. Germany Dental Bone Graft Substitute Market Outlook
  - 7.3.1.1. Market Size & Forecast
    - 7.3.1.1.1. By Value
  - 7.3.1.2. Market Share & Forecast
    - 7.3.1.2.1. By Type
    - 7.3.1.2.2. By Material
    - 7.3.1.2.3. By Mechanism
    - 7.3.1.2.4. By Product
    - 7.3.1.2.5. By Application
    - 7.3.1.2.6. By End User
- 7.3.2. France Dental Bone Graft Substitute Market Outlook
  - 7.3.2.1. Market Size & Forecast
    - 7.3.2.1.1. By Value
  - 7.3.2.2. Market Share & Forecast
    - 7.3.2.2.1. By Type
    - 7.3.2.2.2. By Material
    - 7.3.2.2.3. By Mechanism
    - 7.3.2.2.4. By Product
    - 7.3.2.2.5. By Application
    - 7.3.2.2.6. By End User
- 7.3.3. United Kingdom Dental Bone Graft Substitute Market Outlook
  - 7.3.3.1. Market Size & Forecast
    - 7.3.3.1.1. By Value
  - 7.3.3.2. Market Share & Forecast
    - 7.3.3.2.1. By Type
    - 7.3.3.2.2. By Material
    - 7.3.3.2.3. By Mechanism
    - 7.3.3.2.4. By Product
    - 7.3.3.2.5. By Application
    - 7.3.3.2.6. By End User
- 7.3.4. Italy Dental Bone Graft Substitute Market Outlook
  - 7.3.4.1. Market Size & Forecast
    - 7.3.4.1.1. By Value
  - 7.3.4.2. Market Share & Forecast
    - 7.3.4.2.1. By Type
    - 7.3.4.2.2. By Material
    - 7.3.4.2.3. By Mechanism
    - 7.3.4.2.4. By Product
    - 7.3.4.2.5. By Application
    - 7.3.4.2.6. By End User
- 7.3.5. Spain Dental Bone Graft Substitute Market Outlook
  - 7.3.5.1. Market Size & Forecast
    - 7.3.5.1.1. By Value
  - 7.3.5.2. Market Share & Forecast
    - 7.3.5.2.1. By Type
    - 7.3.5.2.2. By Material
    - 7.3.5.2.3. By Mechanism
    - 7.3.5.2.4. By Product
    - 7.3.5.2.5. By Application
    - 7.3.5.2.6. By End User

8. Asia Pacific Dental Bone Graft Substitute Market Outlook

8.1. Market Size & Forecast
- 8.1.1. By Value
8.2. Market Share & Forecast
- 8.2.1. By Type
- 8.2.2. By Material
- 8.2.3. By Mechanism
- 8.2.4. By Product
- 8.2.5. By Application
- 8.2.6. By End User
- 8.2.7. By Country
8.3. Asia Pacific: Country Analysis
- 8.3.1. China Dental Bone Graft Substitute Market Outlook
  - 8.3.1.1. Market Size & Forecast
    - 8.3.1.1.1. By Value
  - 8.3.1.2. Market Share & Forecast
    - 8.3.1.2.1. By Type
    - 8.3.1.2.2. By Material
    - 8.3.1.2.3. By Mechanism
    - 8.3.1.2.4. By Product
    - 8.3.1.2.5. By Application
    - 8.3.1.2.6. By End User
- 8.3.2. India Dental Bone Graft Substitute Market Outlook
  - 8.3.2.1. Market Size & Forecast
    - 8.3.2.1.1. By Value
  - 8.3.2.2. Market Share & Forecast
    - 8.3.2.2.1. By Type
    - 8.3.2.2.2. By Material
    - 8.3.2.2.3. By Mechanism
    - 8.3.2.2.4. By Product
    - 8.3.2.2.5. By Application
    - 8.3.2.2.6. By End User
- 8.3.3. Japan Dental Bone Graft Substitute Market Outlook
  - 8.3.3.1. Market Size & Forecast
    - 8.3.3.1.1. By Value
  - 8.3.3.2. Market Share & Forecast
    - 8.3.3.2.1. By Type
    - 8.3.3.2.2. By Material
    - 8.3.3.2.3. By Mechanism
    - 8.3.3.2.4. By Product
    - 8.3.3.2.5. By Application
    - 8.3.3.2.6. By End User
- 8.3.4. South Korea Dental Bone Graft Substitute Market Outlook
  - 8.3.4.1. Market Size & Forecast
    - 8.3.4.1.1. By Value
  - 8.3.4.2. Market Share & Forecast
    - 8.3.4.2.1. By Type
    - 8.3.4.2.2. By Material
    - 8.3.4.2.3. By Mechanism
    - 8.3.4.2.4. By Product
    - 8.3.4.2.5. By Application
    - 8.3.4.2.6. By End User
- 8.3.5. Australia Dental Bone Graft Substitute Market Outlook
  - 8.3.5.1. Market Size & Forecast
    - 8.3.5.1.1. By Value
  - 8.3.5.2. Market Share & Forecast
    - 8.3.5.2.1. By Type
    - 8.3.5.2.2. By Material
    - 8.3.5.2.3. By Mechanism
    - 8.3.5.2.4. By Product
    - 8.3.5.2.5. By Application
    - 8.3.5.2.6. By End User

9. Middle East & Africa Dental Bone Graft Substitute Market Outlook

9.1. Market Size & Forecast
- 9.1.1. By Value
9.2. Market Share & Forecast
- 9.2.1. By Type
- 9.2.2. By Material
- 9.2.3. By Mechanism
- 9.2.4. By Product
- 9.2.5. By Application
- 9.2.6. By End User
- 9.2.7. By Country
9.3. Middle East & Africa: Country Analysis
- 9.3.1. Saudi Arabia Dental Bone Graft Substitute Market Outlook
  - 9.3.1.1. Market Size & Forecast
    - 9.3.1.1.1. By Value
  - 9.3.1.2. Market Share & Forecast
    - 9.3.1.2.1. By Type
    - 9.3.1.2.2. By Material
    - 9.3.1.2.3. By Mechanism
    - 9.3.1.2.4. By Product
    - 9.3.1.2.5. By Application
    - 9.3.1.2.6. By End User
- 9.3.2. UAE Dental Bone Graft Substitute Market Outlook
  - 9.3.2.1. Market Size & Forecast
    - 9.3.2.1.1. By Value
  - 9.3.2.2. Market Share & Forecast
    - 9.3.2.2.1. By Type
    - 9.3.2.2.2. By Material
    - 9.3.2.2.3. By Mechanism
    - 9.3.2.2.4. By Product
    - 9.3.2.2.5. By Application
    - 9.3.2.2.6. By End User
- 9.3.3. South Africa Dental Bone Graft Substitute Market Outlook
  - 9.3.3.1. Market Size & Forecast
    - 9.3.3.1.1. By Value
  - 9.3.3.2. Market Share & Forecast
    - 9.3.3.2.1. By Type
    - 9.3.3.2.2. By Material
    - 9.3.3.2.3. By Mechanism
    - 9.3.3.2.4. By Product
    - 9.3.3.2.5. By Application
    - 9.3.3.2.6. By End User

10. South America Dental Bone Graft Substitute Market Outlook

10.1. Market Size & Forecast
- 10.1.1. By Value
10.2. Market Share & Forecast
- 10.2.1. By Type
- 10.2.2. By Material
- 10.2.3. By Mechanism
- 10.2.4. By Product
- 10.2.5. By Application
- 10.2.6. By End User
- 10.2.7. By Country
10.3. South America: Country Analysis
- 10.3.1. Brazil Dental Bone Graft Substitute Market Outlook
  - 10.3.1.1. Market Size & Forecast
    - 10.3.1.1.1. By Value
  - 10.3.1.2. Market Share & Forecast
    - 10.3.1.2.1. By Type
    - 10.3.1.2.2. By Material
    - 10.3.1.2.3. By Mechanism
    - 10.3.1.2.4. By Product
    - 10.3.1.2.5. By Application
    - 10.3.1.2.6. By End User
- 10.3.2. Colombia Dental Bone Graft Substitute Market Outlook
  - 10.3.2.1. Market Size & Forecast
    - 10.3.2.1.1. By Value
  - 10.3.2.2. Market Share & Forecast
    - 10.3.2.2.1. By Type
    - 10.3.2.2.2. By Material
    - 10.3.2.2.3. By Mechanism
    - 10.3.2.2.4. By Product
    - 10.3.2.2.5. By Application
    - 10.3.2.2.6. By End User
- 10.3.3. Argentina Dental Bone Graft Substitute Market Outlook
  - 10.3.3.1. Market Size & Forecast
    - 10.3.3.1.1. By Value
  - 10.3.3.2. Market Share & Forecast
    - 10.3.3.2.1. By Type
    - 10.3.3.2.2. By Material
    - 10.3.3.2.3. By Mechanism
    - 10.3.3.2.4. By Product
    - 10.3.3.2.5. By Application
    - 10.3.3.2.6. By End User

11. Market Dynamics

11.1. Drivers
11.2. Challenges

12. Market Trends & Developments

12.1. Merger & Acquisition (If Any)
12.2. Product Launches (If Any)
12.3. Recent Developments

13. Global Dental Bone Graft Substitute Market: SWOT Analysis

14. Porter's Five Forces Analysis

14.1. Competition in the Industry
14.2. Potential of New Entrants
14.3. Power of Suppliers
14.4. Power of Customers
14.5. Threat of Substitute Products

15. Competitive Landscape

15.1. Dentsply Sirona Inc.
- 15.1.1. Business Overview
- 15.1.2. Products & Services
- 15.1.3. Recent Developments
- 15.1.4. Key Personnel
- 15.1.5. SWOT Analysis
15.2. ZimVie Inc.
15.3. Medtronic plc
15.4. Institut Straumann AG
15.5. Geistlich Pharma AG
15.6. BioHorizons Inc.
15.7. NovaBone Products, LLC
15.8. Botiss Biomaterials GmbH
15.9. LifeNet Health, Inc.
15.10. RTI Surgical Holdings, Inc.